Published in Proc Natl Acad Sci U S A on June 01, 1978
Identification of a set of genes expressed during the G0/G1 transition of cultured mouse cells. EMBO J (1985) 6.31
Dual control of cell growth by somatomedins and platelet-derived growth factor. Proc Natl Acad Sci U S A (1979) 4.32
Sequential expression of protooncogenes during lectin-stimulated mitogenesis of normal human lymphocytes. Proc Natl Acad Sci U S A (1986) 3.19
Induction of c-sis mRNA and activity similar to platelet-derived growth factor by transforming growth factor beta: a proposed model for indirect mitogenesis involving autocrine activity. Proc Natl Acad Sci U S A (1986) 3.04
Specific binding to cultured cells of 125I-labeled type beta transforming growth factor from human platelets. Proc Natl Acad Sci U S A (1984) 3.01
Etiology and pathogenesis of uterine leiomyomas: a review. Environ Health Perspect (2003) 2.98
Mammalian growth-associated H1 histone kinase: a homolog of cdc2+/CDC28 protein kinases controlling mitotic entry in yeast and frog cells. Mol Cell Biol (1989) 2.75
Synthesis of labile, serum-dependent protein in early G1 controls animal cell growth. Proc Natl Acad Sci U S A (1979) 2.28
Mechanisms of pulmonary fibrosis. Spontaneous release of the alveolar macrophage-derived growth factor in the interstitial lung disorders. J Clin Invest (1983) 2.27
Platelet-derived growth factor-induced alterations in vinculin and actin distribution in BALB/c-3T3 cells. J Cell Biol (1985) 2.26
Platelet-derived growth factor-modulated proteins: constitutive synthesis by a transformed cell line. Proc Natl Acad Sci U S A (1981) 1.90
Modulation of alveolar macrophage-driven fibroblast proliferation by alternative macrophage mediators. J Clin Invest (1986) 1.82
Transcriptional regulation of two serum-induced RNAs in mouse fibroblasts: equivalence of one species to B2 repetitive elements. Mol Cell Biol (1985) 1.73
Repression of p27kip1 synthesis by platelet-derived growth factor in BALB/c 3T3 cells. Mol Cell Biol (1996) 1.66
Transforming growth factor beta 1 inhibition of p34cdc2 phosphorylation and histone H1 kinase activity is associated with G1/S-phase growth arrest. Mol Cell Biol (1991) 1.66
Role of fibronectin as a growth factor for fibroblasts. J Cell Biol (1983) 1.64
Synthesis and secretion of platelet-derived growth factor by human breast cancer cell lines. Proc Natl Acad Sci U S A (1987) 1.61
The exosome complex establishes a barricade to erythroid maturation. Blood (2014) 1.48
Alveolar macrophages release an insulin-like growth factor I-type molecule. J Clin Invest (1988) 1.46
Obliterative bronchiolitis after lung transplantation: a fibroproliferative disorder associated with platelet-derived growth factor. Proc Natl Acad Sci U S A (1992) 1.36
Platelet-derived growth factor binds specifically to receptors on vascular smooth muscle cells and the binding becomes nondissociable. Proc Natl Acad Sci U S A (1982) 1.34
Growth-dependent synthesis of c-myc-encoded proteins: early stimulation by serum factors in synchronized mouse 3T3 cells. Mol Cell Biol (1985) 1.34
Cellular ras activity is required for passage through multiple points of the G0/G1 phase in BALB/c 3T3 cells. Mol Cell Biol (1994) 1.33
Post-transcriptional control of the onset of DNA synthesis by an insulin-like growth factor. Mol Cell Biol (1984) 1.31
Platelet-derived growth factor-modulated translatable mRNAs. Mol Cell Biol (1983) 1.30
Inhibition of the mitogenic effects of plasma by a monoclonal antibody to somatomedin C. Proc Natl Acad Sci U S A (1984) 1.30
Transcriptional induction of the murine c-rel gene with serum and phorbol-12-myristate-13-acetate in fibroblasts. Mol Cell Biol (1989) 1.22
Roles of the simian virus 40 tumor antigens in transformation of Chinese hamster lung cells: studies with simian virus 40 double mutants. J Virol (1979) 1.20
Activin A: an autocrine inhibitor of initiation of DNA synthesis in rat hepatocytes. J Clin Invest (1993) 1.18
Modulation of the epidermal growth factor receptor by platelet-derived growth factor and choleragen: effects on mitogenesis. Proc Natl Acad Sci U S A (1982) 1.16
Identification of a BALB/c-3T3 cell protein modulated by platelet-derived growth factor. Mol Cell Biol (1983) 1.14
Acute lung injury. Pathogenesis of intraalveolar fibrosis. J Clin Invest (1991) 1.13
Role of serum components in density-dependent inhibition of growth of cells in culture. Platelet-derived growth factor is the major serum determinant of saturation density. J Cell Biol (1980) 1.11
The platelet-derived growth factor alpha-receptor is encoded by a growth-arrest-specific (gas) gene. Proc Natl Acad Sci U S A (1996) 1.11
Sequential addition of platelet factor and plasma to BALB/c 3T3 fibroblast cultures stimulates somatomedin-C binding early in cell cycle. Proc Natl Acad Sci U S A (1980) 1.10
Multiple kinase arrest points in the G1 phase of nontransformed mammalian cells are absent in transformed cells. Proc Natl Acad Sci U S A (1992) 1.09
Persistence of the mitogenic response to platelet-derived growth factor (competence) does not reflect a long-term interaction between the growth factor and the target cell. J Cell Biol (1983) 1.05
Growth of normal human glial cells in a defined medium containing platelet-derived growth factor. Proc Natl Acad Sci U S A (1980) 1.03
Active proliferation of Rous sarcoma virus-infected, but not normal, chicken heart mesenchymal cells in culture medium of physiological composition. Proc Natl Acad Sci U S A (1980) 1.03
Repression of platelet-derived growth factor beta-receptor expression by mitogenic growth factors and transforming oncogenes in murine 3T3 fibroblasts. Mol Cell Biol (1995) 1.01
Analysis of cyclin D3-cdk4 complexes in fibroblasts expressing and lacking p27(kip1) and p21(cip1). Mol Cell Biol (2000) 0.98
Regulation of insulin-like growth factor I gene expression in the human macrophage-like cell line U937. J Clin Invest (1990) 0.92
Insulin-like growth factor II mediates epidermal growth factor-induced mitogenesis in cervical cancer cells. Proc Natl Acad Sci U S A (1995) 0.87
Phospholipid turnover during cell-cycle traverse in synchronous Chinese-hamster ovary cells. Mitogenesis without phosphoinositide breakdown. Biochem J (1988) 0.86
Colony-stimulating factor (CSF) controls proliferation of CSF-dependent cells by acting during the G1 phase of the cell cycle. Proc Natl Acad Sci U S A (1984) 0.84
Basic fibroblast growth factor expression is regulated by corticotropin in the human fetal adrenal: a model for adrenal growth regulation. Proc Natl Acad Sci U S A (1991) 0.83
Mode of fibroblast growth enhancement by human interleukin-1. J Cell Biol (1988) 0.83
Partial purification and characterization of a growth factor present in goat's colostrum. Similarities with platelet-derived growth factor. Biochem J (1984) 0.83
Aproliferin--a human plasma protein that induces the irreversible loss of proliferative potential associated with terminal differentiation. Am J Pathol (1986) 0.83
Ras proteins are essential and selective for the action of insulin-like growth factor 1 late in the G1 phase of the cell cycle in BALB/c murine fibroblasts. Proc Natl Acad Sci U S A (1992) 0.81
Origin of platelet-derived growth factor in megakaryocytes in guinea pigs. J Clin Invest (1980) 0.81
Platelet-derived growth factor stimulates synthesis of 1,2-diacylglycerol from monoacylglycerol in Balb/c 3T3 cells. Biochem J (1989) 0.81
Analysis of the genes involved in the insulin transmembrane mitogenic signal in Chinese hamster ovary cells, CHO-K1, utilizing insulin-independent mutants. Proc Natl Acad Sci U S A (1991) 0.80
Regulation of the g1/s transition in hepatocytes: involvement of the cyclin-dependent kinase cdk1 in the DNA replication. Int J Hepatol (2012) 0.79
Control of differentiation in BC3H1 muscle cells. Environ Health Perspect (1989) 0.78
p27Kip1 inhibits the cell cycle through non-canonical G1/S phase-specific gatekeeper mechanism. Cell Cycle (2015) 0.77
Unraveling Growth Factor Signaling and Cell Cycle Progression in Individual Fibroblasts. J Biol Chem (2016) 0.75
Platelet-derived growth factor (PDGF)-AB-mediated phosphorylation of PDGF beta receptors. Biochem J (1994) 0.75
The initiation of cell division in a contact-inhibited mammalian cell line. J Cell Physiol (1965) 12.07
A platelet-dependent serum factor that stimulates the proliferation of arterial smooth muscle cells in vitro. Proc Natl Acad Sci U S A (1974) 9.94
A restriction point for control of normal animal cell proliferation. Proc Natl Acad Sci U S A (1974) 8.74
"Contact inhibition" of cell division in 3T3 cells. Proc Natl Acad Sci U S A (1968) 7.42
Induction of DNA synthesis in BALB/c 3T3 cells by serum components: reevaluation of the commitment process. Proc Natl Acad Sci U S A (1977) 5.20
Do cells cycle? Proc Natl Acad Sci U S A (1973) 5.20
Platelets as a source of fibroblast growth-promoting activity. Exp Cell Res (1974) 4.68
Platelet factors stimulate fibroblasts and smooth muscle cells quiescent in plasma serum to proliferate. J Cell Biol (1976) 3.48
Inhibition of ribonucleoside diphosphate reductase by hydroxyurea. Cancer Res (1968) 2.67
Continuous protein synthesis is required to maintain the probability of entry into S phase. Cell (1977) 2.63
Radioimmunoassay of a human serum growth factor for Balb/c-3T3 cells: derivation from platelets. Proc Natl Acad Sci U S A (1977) 2.61
Isolation of a cationic polypeptide from human serum that stimulates proliferation of 3T3 cells. Proc Natl Acad Sci U S A (1975) 2.58
Conditions limiting multiplication of fibroblastic and epithelial cells in dense cultures. Nature (1973) 2.52
Regulation of fibroblast cell cycle by serum. Nature (1976) 2.02
Hydroxyurea does not prevent synchronized G1 chinese hamster cells from entering the DNA synthetic period. Biochem Biophys Res Commun (1976) 1.50
Verbal conditioning of middle and lower socioeconomic class schizophrenics. J Abnorm Psychol (1977) 1.42
Effects of withdrawal of a mitogenic stimulus on progression of fibroblasts into S phase: differences between serum and purified multiplication-stimulating activity. J Cell Physiol (1977) 0.97
Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor. Cell (1983) 17.87
Simian sarcoma virus onc gene, v-sis, is derived from the gene (or genes) encoding a platelet-derived growth factor. Science (1983) 9.06
Molecular cloning of gene sequences regulated by platelet-derived growth factor. Cell (1983) 9.03
Direct transformation of 3T3 cells by Abelson murine leukaemia virus. Nature (1975) 5.97
Induction of DNA synthesis in BALB/c 3T3 cells by serum components: reevaluation of the commitment process. Proc Natl Acad Sci U S A (1977) 5.20
Expression of the c-fos gene and of an fos-related gene is stimulated by platelet-derived growth factor. Science (1984) 4.87
Purification of human platelet-derived growth factor. Proc Natl Acad Sci U S A (1979) 4.78
Functional role for c-myc in mitogenic response to platelet-derived growth factor. Nature (1984) 4.56
Dual control of cell growth by somatomedins and platelet-derived growth factor. Proc Natl Acad Sci U S A (1979) 4.32
Sonic hedgehog--regulated oligodendrocyte lineage genes encoding bHLH proteins in the mammalian central nervous system. Neuron (2000) 4.17
Cloning and expression of JE, a gene inducible by platelet-derived growth factor and whose product has cytokine-like properties. Proc Natl Acad Sci U S A (1988) 3.83
In vitro transformation of lymphoid cells by Abelson murine leukemia virus. Proc Natl Acad Sci U S A (1975) 3.47
Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis. Proc Natl Acad Sci U S A (2001) 3.29
Separation of sarcoma virus-specific and leukemia virus-specific genetic sequences of Moloney sarcoma virus. Proc Natl Acad Sci U S A (1975) 3.28
Platelet-derived growth factor and the regulation of the mammalian fibroblast cell cycle. Biochim Biophys Acta (1979) 3.26
Structural and immunological similarities between simian sarcoma virus gene product(s) and human platelet-derived growth factor. Nature (1983) 3.01
Platelet-derived growth factor and double-stranded ribonucleic acids stimulate expression of the same genes in 3T3 cells. Cell (1985) 2.82
Platelet-derived growth factor induces rapid and sustained tyrosine phosphorylation of phospholipase C-gamma in quiescent BALB/c 3T3 cells. Mol Cell Biol (1989) 2.78
Radioimmunoassay of a human serum growth factor for Balb/c-3T3 cells: derivation from platelets. Proc Natl Acad Sci U S A (1977) 2.61
Isolation of a cationic polypeptide from human serum that stimulates proliferation of 3T3 cells. Proc Natl Acad Sci U S A (1975) 2.58
Induction of cell division in medium lacking serum growth factor by SV40. Virology (1971) 2.48
Isoleucine and valine metabolism in Escherichia coli. XXII. A pleiotropic mutation affecting induction of isomeroreductase activity. J Bacteriol (1973) 2.31
The platelet-derived growth factor-inducible KC gene encodes a secretory protein related to platelet alpha-granule proteins. J Biol Chem (1989) 2.29
Platelet-derived growth factor-induced alterations in vinculin and actin distribution in BALB/c-3T3 cells. J Cell Biol (1985) 2.26
Impact of chronic transfusion on incidence of pain and acute chest syndrome during the Stroke Prevention Trial (STOP) in sickle-cell anemia. J Pediatr (2001) 2.24
Platelet alpha granules contain a growth factor for fibroblasts. Blood (1979) 2.18
Role of platelet-derived growth factor in wound healing: synergistic effects with other growth factors. Proc Natl Acad Sci U S A (1987) 2.17
Epidermal growth factor (EGF) and somatomedin C regulate G1 progression in competent BALB/c-3T3 cells. Exp Cell Res (1982) 2.13
Human platelet-derived growth factor (PDGF): purification of PDGF-I and PDGF-II and separation of their reduced subunits. Proc Natl Acad Sci U S A (1981) 2.08
Isoleucine and valine metabolism in Escherichia coli. XX. Multiple forms of acetohydroxy acid synthetase. Biochem Biophys Res Commun (1972) 2.07
Induction of p21WAF1/CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: role of activated STAT3 signaling. Oncogene (2000) 2.06
Growth factors in wound healing. Single and synergistic effects on partial thickness porcine skin wounds. J Clin Invest (1989) 2.04
Simian sarcoma virus--transformed cells secrete a mitogen identical to platelet-derived growth factor. Science (1984) 1.97
Regulation of the cell cycle machinery by oncogenic ras. Oncogene (1996) 1.92
Platelet-derived growth factor-modulated proteins: constitutive synthesis by a transformed cell line. Proc Natl Acad Sci U S A (1981) 1.90
The molecular biology of platelet-derived growth factor. Cell (1983) 1.88
Insulin and obesity in the Zucker genetically obese rat "fatty". Endocrinology (1972) 1.88
Transforming viruses directly reduce the cellular growth requirement for a platelet derived growth factor. J Cell Physiol (1978) 1.79
Isoleucine and valine metabolism in Escherichia coli. XXI. Mutations affecting derepression and valine resistance. J Bacteriol (1973) 1.75
Constitutional 1p36 deletion in a child with neuroblastoma. Am J Hum Genet (1993) 1.75
Adhesion to fibronectin via beta1 integrins regulates p27kip1 levels and contributes to cell adhesion mediated drug resistance (CAM-DR). Oncogene (2000) 1.75
Expression of PDGF and PDGF receptors in human astrocytoma operation specimens supports the existence of an autocrine loop. Int J Cancer (1995) 1.69
Induction of erythroid leukaemia by Harvey and Kirsten sarcoma viruses. Nature (1975) 1.68
Repression of p27kip1 synthesis by platelet-derived growth factor in BALB/c 3T3 cells. Mol Cell Biol (1996) 1.66
Hedgehog-dependent oligodendrocyte lineage specification in the telencephalon. Development (2001) 1.62
Synthesis and secretion of platelet-derived growth factor by human breast cancer cell lines. Proc Natl Acad Sci U S A (1987) 1.61
Platelet-derived growth factor receptor alpha-subunit gene (Pdgfra) is deleted in the mouse patch (Ph) mutation. Proc Natl Acad Sci U S A (1991) 1.61
Regulation of c-myc and c-fos mRNA levels by polyomavirus: distinct roles for the capsid protein VP1 and the viral early proteins. Proc Natl Acad Sci U S A (1987) 1.58
Dissociation of cell division stimulating capacity for Balb-c-3T3 from the insulin-like activity in human serum. Nature (1974) 1.55
Expression of androgen and progesterone receptors in primary human meningiomas. J Neurosurg (1993) 1.54
Serum-inducible genes. Adv Cancer Res (1989) 1.53
A new platelet-derived growth factor-regulated genomic element which binds a serine/threonine phosphoprotein mediates induction of the slow immediate-early gene MCP-1. Mol Cell Biol (1995) 1.49
Growth inhibition and modulation of kinase pathways of small cell lung cancer cell lines by the novel tyrosine kinase inhibitor STI 571. Oncogene (2000) 1.47
Expression of angiogenic growth factor genes in primary human astrocytomas may contribute to their growth and progression. Cancer Res (1991) 1.46
Elevated expression of monocyte chemoattractant protein 1 by vascular smooth muscle cells in hypercholesterolemic primates. Proc Natl Acad Sci U S A (1992) 1.42
Neurotrophic protein S100 beta stimulates glial cell proliferation. Proc Natl Acad Sci U S A (1991) 1.40
Effect of pseudotype on Abelson virus and Kirsten sarcoma virus-induced leukemia. J Exp Med (1978) 1.40
Intracranial inhibition of platelet-derived growth factor-mediated glioblastoma cell growth by an orally active kinase inhibitor of the 2-phenylaminopyrimidine class. Cancer Res (2000) 1.39
Abelson virus-transformed lymphocytes: null cells that modulate H-2. Cell (1977) 1.37
The tumor promoter 12-O-tetradecanoyl-phorbol-13-acetate enhances the proliferative response of Balb/c-3T3 cells to hormonal growth factors. J Cell Physiol (1979) 1.37
Platelet-derived growth factor A chain is maternally encoded in Xenopus embryos. Science (1988) 1.37
Epidermal growth factor (EGF) is required only during the traverse of early G1 in PDGF stimulated density-arrested BALB/c-3T3 cells. Exp Cell Res (1983) 1.36
Regulation of cytoskeletal architecture by platelet-derived growth factor, insulin and epidermal growth factor. Exp Cell Res (1984) 1.36
Platelet-dependent stimulation of prostacyclin synthesis by platelet-derived growth factor. Nature (1980) 1.35
Platelet-derived growth factor binds specifically to receptors on vascular smooth muscle cells and the binding becomes nondissociable. Proc Natl Acad Sci U S A (1982) 1.34
Synthesis and secretion of proteins resembling platelet-derived growth factor by human glioblastoma and fibrosarcoma cells in culture. Proc Natl Acad Sci U S A (1985) 1.33
Human platelet-derived growth factor (PDGF): amino-terminal amino acid sequence. Science (1983) 1.30
Platelet-derived growth factor-modulated translatable mRNAs. Mol Cell Biol (1983) 1.30
Centriole deciliation associated with the early response of 3T3 cells to growth factors but not to SV40. Cell (1979) 1.30
Inhibition of the mitogenic effects of plasma by a monoclonal antibody to somatomedin C. Proc Natl Acad Sci U S A (1984) 1.30
Dominant-negative mutants of platelet-derived growth factor revert the transformed phenotype of human astrocytoma cells. Mol Cell Biol (1993) 1.29
Oligodendrocyte lineage genes (OLIG) as molecular markers for human glial brain tumors. Proc Natl Acad Sci U S A (2001) 1.29
Phylogenetic analysis of platelet-derived growth factor by radio-receptor assay. J Cell Biol (1982) 1.28
Expression of the neurotrophin receptor TrkC is linked to a favorable outcome in medulloblastoma. Proc Natl Acad Sci U S A (1994) 1.27
Interferon inhibits the establishment of competence in Go/S-phase transition. Science (1986) 1.26
Detection of c-sis transcripts and synthesis of PDGF-like proteins by human osteosarcoma cells. Science (1984) 1.26
Ectopic expression of Olig1 promotes oligodendrocyte formation and reduces neuronal survival in developing mouse cortex. Nat Neurosci (2001) 1.26
A combination of platelet-derived and insulin-like growth factors enhances periodontal regeneration. J Clin Periodontol (1989) 1.24
Control of the Balb/c-3T3 cell cycle by nutrients and serum factors: analysis using platelet-derived growth factor and platelet-poor plasma. J Cell Physiol (1979) 1.24
Purified human platelet-derived growth factor receptor has ligand-stimulated tyrosine kinase activity. Proc Natl Acad Sci U S A (1986) 1.24