Published in Nature on July 17, 1975
Envelope gene sequences which encode the gp52 protein of spleen focus-forming virus are required for the induction of erythroid cell proliferation. J Virol (1982) 2.39
Identification of a 30S RNA with properties of a defective type C virus in murine cells. J Virol (1978) 2.34
Involvement of ras in sexual differentiation but not in growth control in fission yeast. EMBO J (1986) 2.31
Characterizatiion of rat genetic sequences of Kirsten sarcoma virus: distinct class of endogenous rat type C viral sequences. J Virol (1976) 2.09
Transforming genes of human hematopoietic tumors: frequent detection of ras-related oncogenes whose activation appears to be independent of tumor phenotype. Proc Natl Acad Sci U S A (1983) 2.04
Long terminal repeat sequences impart hematopoietic transformation properties to the myeloproliferative sarcoma virus. Proc Natl Acad Sci U S A (1985) 1.88
Biological activity of the spleen focus-forming virus is encoded by a molecularly cloned subgenomic fragment of spleen focus-forming virus DNA. Proc Natl Acad Sci U S A (1981) 1.86
Myeloproliferative virus, a cloned murine sarcoma virus with spleen focus-forming properties in adult mice. J Virol (1980) 1.85
Markedly elevated levels of an endogenous sarc protein in a hemopoietic precursor cell line. Mol Cell Biol (1981) 1.83
Construction and isolation of a transforming murine retrovirus containing the src gene of Rous sarcoma virus. J Virol (1983) 1.63
BALB- and Harvey-murine sarcoma virus transformation of a novel lymphoid progenitor cell. J Exp Med (1982) 1.42
Effect of pseudotype on Abelson virus and Kirsten sarcoma virus-induced leukemia. J Exp Med (1978) 1.40
Prediction of the three-dimensional structure of the transforming region of the EJ/T24 human bladder oncogene product and its normal cellular homologue. Proc Natl Acad Sci U S A (1983) 1.37
Friend murine leukemia virus-immortalized myeloid cells are converted into tumorigenic cell lines by Abelson leukemia virus. Proc Natl Acad Sci U S A (1985) 1.34
In vitro translation of Harvey murine sarcoma virus RNA. J Virol (1977) 1.32
Molecular cloning and characterization of a leukemia-inducing myeloproliferative sarcoma virus and two of its temperature-sensitive mutants. J Virol (1984) 1.20
Introduction of v-Ha-ras oncogene induces differentiation of cultured human medullary thyroid carcinoma cells. Proc Natl Acad Sci U S A (1987) 1.20
In vitro-derived leukemic erythroid cell lines induced by a raf- and myc-containing retrovirus differentiate in response to erythropoietin. Proc Natl Acad Sci U S A (1988) 1.05
P21 v-ras inhibits induction of c-myc and c-fos expression by platelet-derived growth factor. Mol Cell Biol (1988) 1.03
Insertion of the v-Ha-ras oncogene induces differentiation of calcitonin-producing human small cell lung cancer. J Clin Invest (1989) 0.98
An altered DNA sequence encompassing the ras gene of Harvey murine sarcoma virus. Nucleic Acids Res (1984) 0.89
Recombinant BALB and Harvey sarcoma viruses with normal proto-ras-coding regions transform embryo cells in culture and cause tumors in mice. J Virol (1989) 0.88
Regional localization of two human cellular Kirsten ras genes on chromosomes 6 and 12. Mol Cell Biol (1984) 0.80
Generation of recombinant murine retroviral genomes containing the v-src oncogene: isolation of a virus inducing hemangiosarcomas in the brain. J Virol (1991) 0.79
Oncogenicity of human N-ras oncogene and proto-oncogene introduced into retroviral vectors. J Virol (1989) 0.78
Development of transforming function during transduction of proto-ras into Harvey sarcoma virus. Proc Natl Acad Sci U S A (1994) 0.76
Mechanism of activation of a human oncogene. Nature (1982) 12.09
Active human immunodeficiency virus protease is required for viral infectivity. Proc Natl Acad Sci U S A (1988) 10.77
Monoclonal antibodies to the p21 products of the transforming gene of Harvey murine sarcoma virus and of the cellular ras gene family. J Virol (1982) 8.88
The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes. Nature (1981) 8.44
Helper-independent transformation by unintegrated Harvey sarcoma virus DNA. J Virol (1978) 7.75
Whole-genome association study of bipolar disorder. Mol Psychiatry (2008) 6.80
Induction of murine C-type viruses from clonal lines of virus-free BALB-3T3 cells. Science (1971) 6.71
Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 molecules. Proc Natl Acad Sci U S A (1984) 6.45
Direct transformation of 3T3 cells by Abelson murine leukaemia virus. Nature (1975) 5.97
Cloning of bovine GAP and its interaction with oncogenic ras p21. Nature (1988) 5.56
Analysis of two divergent rat genomic clones homologous to the transforming gene of Harvey murine sarcoma virus. Proc Natl Acad Sci U S A (1981) 5.51
ras-Related gene sequences identified and isolated from Saccharomyces cerevisiae. Nature (1984) 5.32
Studies on the nucleic acid sequences of Kirsten sarcoma virus: a model for formation of a mammalian RNA-containing sarcoma virus. J Virol (1973) 5.28
Induction of DNA synthesis in BALB/c 3T3 cells by serum components: reevaluation of the commitment process. Proc Natl Acad Sci U S A (1977) 5.20
Tumorigenic transformation of mammalian cells induced by a normal human gene homologous to the oncogene of Harvey murine sarcoma virus. Nature (1982) 5.08
RNA in mammalian sarcoma virus transformed nonproducer cells homologous to murine leukemia virus RNA. Virology (1973) 5.04
Transfection of molecularly cloned Friend murine leukemia virus DNA yields a highly leukemogenic helper-independent type C virus. J Virol (1980) 4.91
Purification of human platelet-derived growth factor. Proc Natl Acad Sci U S A (1979) 4.78
The transforming proteins of Rous sarcoma virus, Harvey sarcoma virus and Abelson virus contain tightly bound lipid. Cell (1982) 4.66
Dual evolutionary origin for the rat genetic sequences of Harvey murine sarcoma virus. J Virol (1980) 4.63
Construction and isolation of a transmissible retrovirus containing the src gene of Harvey murine sarcoma virus and the thymidine kinase gene of herpes simplex virus type 1. J Virol (1981) 4.54
Guanine nucleotide-binding and autophosphorylating activities associated with the p21src protein of Harvey murine sarcoma virus. Nature (1980) 4.43
Localization of the src gene product of the Harvey strain of MSV to plasma membrane of transformed cells by electron microscopic immunocytochemistry. Cell (1980) 4.35
Guanine nucleotide-binding activity as an assay for src protein of rat-derived murine sarcoma viruses. Proc Natl Acad Sci U S A (1979) 4.34
Dual control of cell growth by somatomedins and platelet-derived growth factor. Proc Natl Acad Sci U S A (1979) 4.32
Requirement of either of a pair of ras-related genes of Saccharomyces cerevisiae for spore viability. Nature (1984) 4.23
Harvey sarcoma virus: a second murine type C sarcoma virus with rat genetic information. J Virol (1974) 3.92
Molecular cloning of the Harvey sarcoma virus closed circular DNA intermediates: initial structural and biological characterization. J Virol (1979) 3.90
Separation of murine cellular and murine leukaemia virus DNA polymerases. Nat New Biol (1971) 3.71
Friend strain of spleen focus-forming virus: a recombinant between mouse type C ecotropic viral sequences and sequences related to xenotropic virus. J Virol (1977) 3.70
Friend strain of spleen focus-forming virus is a recombinant between ecotropic murine type C virus and the env gene region of xenotropic type C virus. Proc Natl Acad Sci U S A (1977) 3.62
Mutant ras-encoded proteins with altered nucleotide binding exert dominant biological effects. Proc Natl Acad Sci U S A (1986) 3.59
Human genome contains four genes homologous to transforming genes of Harvey and Kirsten murine sarcoma viruses. Proc Natl Acad Sci U S A (1982) 3.48
In vitro transformation of lymphoid cells by Abelson murine leukemia virus. Proc Natl Acad Sci U S A (1975) 3.47
Separation of sarcoma virus-specific and leukemia virus-specific genetic sequences of Moloney sarcoma virus. Proc Natl Acad Sci U S A (1975) 3.28
Platelet-derived growth factor and the regulation of the mammalian fibroblast cell cycle. Biochim Biophys Acta (1979) 3.26
Radioimmunoassay of mammalian type C viral proteins. I. Species specific reactions of murine and feline viruses. J Immunol (1972) 3.23
Proposal for naming host cell-derived inserts in retrovirus genomes. J Virol (1981) 3.18
Identification of effector residues and a neutralizing epitope of Ha-ras-encoded p21. Proc Natl Acad Sci U S A (1986) 3.11
Mammalian and yeast ras gene products: biological function in their heterologous systems. Science (1985) 3.03
p21 of Kirsten murine sarcoma virus is thermolabile in a viral mutant temperature sensitive for the maintenance of transformation. J Virol (1979) 2.94
Comparative biochemical properties of p21 ras molecules coded for by viral and cellular ras genes. J Virol (1982) 2.91
Radioimmunoassay of mammalian type-C viral proteins: interspecies antigenic reactivities of the major internal polypeptide. Proc Natl Acad Sci U S A (1972) 2.90
Identification of a precursor in the biosynthesis of the p21 transforming protein of harvey murine sarcoma virus. J Virol (1982) 2.89
Yeast and mammalian ras proteins have conserved biochemical properties. Nature (1985) 2.85
Distinct mechanism for antidepressant activity by blockade of central substance P receptors. Science (1998) 2.83
Heteroduplex analysis of the sequence relations between the RNAs of mink cell focus-inducing and murine leukemia viruses. J Virol (1978) 2.79
Immunological characterization of primate C-type virus reverse transcriptases. Nat New Biol (1972) 2.73
An ordered sequence of events is required before BALB/c-3T3 cells become committed to DNA synthesis. Proc Natl Acad Sci U S A (1978) 2.71
Type C particle-positive and type C particle-negative rat cell lines: characterization of the coding capacity of endogenous sarcoma virus-specific RNA. J Virol (1976) 2.67
Comparison of the genomic organization of Kirsten and Harvey sarcoma viruses. J Virol (1978) 2.66
Immunological relationships of reverse transcriptases from ribonucleic acid tumor viruses. J Virol (1972) 2.65
Radioimmunoassay of a human serum growth factor for Balb/c-3T3 cells: derivation from platelets. Proc Natl Acad Sci U S A (1977) 2.61
Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor. Science (1993) 2.60
Isolation of a cationic polypeptide from human serum that stimulates proliferation of 3T3 cells. Proc Natl Acad Sci U S A (1975) 2.58
Rapid leukemia induced by cloned friend strain of replicating murine type-C virus. Association with induction of xenotropic-related RNA sequences contained in spleen focus-forming virus. Virology (1978) 2.56
Modulation of guanine nucleotides bound to Ras in NIH3T3 cells by oncogenes, growth factors, and the GTPase activating protein (GAP). J Biol Chem (1990) 2.49
Induction of cell division in medium lacking serum growth factor by SV40. Virology (1971) 2.48
Helper-independent mink cell focus-inducing strains of Friend murine type-C virus: potential relationship to the origin of replication-defective spleen focus-forming virus. J Exp Med (1978) 2.48
Isolation of a fibroblast nonproducer cell line containing the Friend strain of the spleen focus-forming virus. Virology (1977) 2.47
Nature and distribution of feline sarcoma virus nucleotide sequences. J Virol (1979) 2.47
Functional organization of the Harvey murine sarcoma virus genome. J Virol (1980) 2.46
Flat revertants isolated from Kirsten sarcoma virus-transformed cells are resistant to the action of specific oncogenes. Proc Natl Acad Sci U S A (1983) 2.44
Purification of ras GTPase activating protein from bovine brain. Proc Natl Acad Sci U S A (1988) 2.41
Deletion mapping of moloney type C virus: polypeptide and nucleic acid expression in different transforming virus isolates. J Virol (1976) 2.39
Envelope gene sequences which encode the gp52 protein of spleen focus-forming virus are required for the induction of erythroid cell proliferation. J Virol (1982) 2.39
RNA dependent DNA polymerase activity in mammalian cells. Nature (1971) 2.37
Dexamethasone stimulation of murine mammary tumor virus expression: a tissue culture source of virus. Science (1974) 2.34
Identification of a 30S RNA with properties of a defective type C virus in murine cells. J Virol (1978) 2.34
Defective retrovirus-like 30S RNA species of rat and mouse cells are infectious if packaged by type C helper virus. J Virol (1979) 2.34
Steroid induction of mouse mammary tumor virus: effect upon synthesis and degradation of viral RNA. J Virol (1977) 2.26
Impact of chronic transfusion on incidence of pain and acute chest syndrome during the Stroke Prevention Trial (STOP) in sickle-cell anemia. J Pediatr (2001) 2.24
Platelet alpha granules contain a growth factor for fibroblasts. Blood (1979) 2.18
Identification of a normal vertebrate cell protein related to the p21 src of Harvey murine sarcoma virus. Virology (1980) 2.15
A C-terminal domain of GAP is sufficient to stimulate ras p21 GTPase activity. EMBO J (1989) 2.14
Radioimmunoassay of mammalian type C viral proteins. 3. Detection of viral antigen in normal murine cells and tissues. J Exp Med (1973) 2.13
Nucleotide sequence of two rasH related-genes isolated from the yeast Saccharomyces cerevisiae. Nucleic Acids Res (1984) 2.10
Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder. Mol Psychiatry (2012) 2.09
Characterizatiion of rat genetic sequences of Kirsten sarcoma virus: distinct class of endogenous rat type C viral sequences. J Virol (1976) 2.09
Transformation by cloned Harvey murine sarcoma virus DNA: efficiency increased by long terminal repeat DNA. Science (1980) 2.05
Different rat-derived transforming retroviruses code for an immunologically related intracellular phosphoprotein. Proc Natl Acad Sci U S A (1979) 1.98
Platelet-derived growth factor-modulated proteins: constitutive synthesis by a transformed cell line. Proc Natl Acad Sci U S A (1981) 1.90
Primate and murine type-C viral nucleic acid association kinetics: analysis of model systems and natural tissues. J Virol (1974) 1.89
Levels of rat cellular RNA homologous to either Kirsten sarcoma virus or rat type-C virus in cell lines derived from Osborne-Mendel rats. J Virol (1974) 1.86
Biological activity of the spleen focus-forming virus is encoded by a molecularly cloned subgenomic fragment of spleen focus-forming virus DNA. Proc Natl Acad Sci U S A (1981) 1.86
Antibody to the RNA-dependent DNA polymerase of mammalian C-type RNA tumor viruses. Proc Natl Acad Sci U S A (1971) 1.86
Base sequence differences between the RNA components of Harvey sarcoma virus. J Virol (1975) 1.84
Anthrax lethal factor inhibition. Proc Natl Acad Sci U S A (2005) 1.83
Heteroduplex analysis of cloned rat endogenous replication-defective (30 S) retrovirus and Harvey murine sarcoma virus. Virology (1980) 1.81
Separation of RNA-dependent DNA polymerase activity from the murine leukaemia virion. Nature (1970) 1.80
Transforming viruses directly reduce the cellular growth requirement for a platelet derived growth factor. J Cell Physiol (1978) 1.79
Neutralizing monoclonal antibodies to hepatitis A virus: partial localization of a neutralizing antigenic site. J Virol (1984) 1.78
Mammary tumor virus induction by glucocorticoids. Characterization of specific transcriptional regulation. J Biol Chem (1975) 1.76
Constitutional 1p36 deletion in a child with neuroblastoma. Am J Hum Genet (1993) 1.75
Biochemical and physiological mechanisms in glucocorticoid hormone induction of mouse mammary tumor virus. Virology (1976) 1.74
Identification of guanine nucleotides bound to ras-encoded proteins in growing yeast cells. J Biol Chem (1987) 1.74