Published in Cell Stem Cell on December 01, 2016
Zika virus has oncolytic activity against glioblastoma stem cells. J Exp Med (2017) 1.40
A novel Zika virus mouse model reveals strain specific differences in virus pathogenesis and host inflammatory immune responses. PLoS Pathog (2017) 0.85
Using brain organoids to understand Zika virus-induced microcephaly. Development (2017) 0.77
How does Zika virus cause microcephaly? Genes Dev (2017) 0.76
Zika virus directly infects peripheral neurons and induces cell death. Nat Neurosci (2017) 0.75
Experimental study of tuberculosis: From animal models to complex cell systems and organoids. PLoS Pathog (2017) 0.75
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell (2006) 120.51
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science (1996) 28.95
Zika virus. I. Isolations and serological specificity. Trans R Soc Trop Med Hyg (1952) 13.73
Development and applications of CRISPR-Cas9 for genome engineering. Cell (2014) 13.50
The envelope glycoprotein from tick-borne encephalitis virus at 2 A resolution. Nature (1995) 12.25
Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study. Lancet (2016) 10.08
The cell biology of neurogenesis. Nat Rev Mol Cell Biol (2005) 9.35
Structure of dengue virus: implications for flavivirus organization, maturation, and fusion. Cell (2002) 9.13
Cerebral organoids model human brain development and microcephaly. Nature (2013) 9.07
Zika Virus Associated with Microcephaly. N Engl J Med (2016) 9.03
Stem cells: units of development, units of regeneration, and units in evolution. Cell (2000) 7.36
Zika Virus and Birth Defects--Reviewing the Evidence for Causality. N Engl J Med (2016) 6.01
The Brazilian Zika virus strain causes birth defects in experimental models. Nature (2016) 4.71
Composition and three-dimensional architecture of the dengue virus replication and assembly sites. Cell Host Microbe (2009) 4.54
Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth. Cell Stem Cell (2016) 4.54
Development and evolution of the human neocortex. Cell (2011) 4.42
Antibody-enhanced dengue virus infection in primate leukocytes. Nature (1977) 4.18
Biology of Zika Virus Infection in Human Skin Cells. J Virol (2015) 3.87
Proteolytic activation of tick-borne encephalitis virus by furin. J Virol (1997) 3.78
Global landscape of HIV-human protein complexes. Nature (2011) 3.70
Zika virus impairs growth in human neurospheres and brain organoids. Science (2016) 3.57
Detection of Zika virus in urine. Emerg Infect Dis (2015) 3.52
Isolation and directed differentiation of neural crest stem cells derived from human embryonic stem cells. Nat Biotechnol (2007) 3.48
Zika Virus Infection during Pregnancy in Mice Causes Placental Damage and Fetal Demise. Cell (2016) 3.42
Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure. Cell (2016) 3.33
Zika Virus Infection with Prolonged Maternal Viremia and Fetal Brain Abnormalities. N Engl J Med (2016) 3.25
A Mouse Model of Zika Virus Pathogenesis. Cell Host Microbe (2016) 3.20
Zika Virus Disrupts Neural Progenitor Development and Leads to Microcephaly in Mice. Cell Stem Cell (2016) 2.92
Hepatitis C virus infection protein network. Mol Syst Biol (2008) 2.91
Zika virus infection of the central nervous system of mice. Arch Gesamte Virusforsch (1971) 2.63
Zika virus and microcephaly: why is this situation a PHEIC? Lancet (2016) 2.56
Specificity, cross-reactivity, and function of antibodies elicited by Zika virus infection. Science (2016) 2.53
Dengue virus-induced autophagy regulates lipid metabolism. Cell Host Microbe (2010) 2.49
The Murray Valley encephalitis virus prM protein confers acid resistance to virus particles and alters the expression of epitopes within the R2 domain of E glycoprotein. Virology (1992) 2.48
Evidence of Sexual Transmission of Zika Virus. N Engl J Med (2016) 2.35
Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells. Nat Biotechnol (2012) 2.33
Expression Analysis Highlights AXL as a Candidate Zika Virus Entry Receptor in Neural Stem Cells. Cell Stem Cell (2016) 2.32
Interaction of TIA-1/TIAR with West Nile and dengue virus products in infected cells interferes with stress granule formation and processing body assembly. Proc Natl Acad Sci U S A (2007) 2.30
STING and the innate immune response to nucleic acids in the cytosol. Nat Immunol (2013) 2.23
Single-Cell RNA-Seq with Waterfall Reveals Molecular Cascades underlying Adult Neurogenesis. Cell Stem Cell (2015) 2.06
Derivation of neural crest cells from human pluripotent stem cells. Nat Protoc (2010) 2.05
FOXG1-Dependent Dysregulation of GABA/Glutamate Neuron Differentiation in Autism Spectrum Disorders. Cell (2015) 1.94
G3BP1, G3BP2 and CAPRIN1 are required for translation of interferon stimulated mRNAs and are targeted by a dengue virus non-coding RNA. PLoS Pathog (2014) 1.84
A Screen of FDA-Approved Drugs for Inhibitors of Zika Virus Infection. Cell Host Microbe (2016) 1.83
Dengue subgenomic RNA binds TRIM25 to inhibit interferon expression for epidemiological fitness. Science (2015) 1.82
Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture. Nat Methods (2015) 1.82
DENV inhibits type I IFN production in infected cells by cleaving human STING. PLoS Pathog (2012) 1.80
Type III Interferons Produced by Human Placental Trophoblasts Confer Protection against Zika Virus Infection. Cell Host Microbe (2016) 1.72
The IKK-related kinases: from innate immunity to oncogenesis. Cell Res (2008) 1.71
Zika Virus Depletes Neural Progenitors in Human Cerebral Organoids through Activation of the Innate Immune Receptor TLR3. Cell Stem Cell (2016) 1.69
Efficient derivation of microglia-like cells from human pluripotent stem cells. Nat Med (2016) 1.64
DNA methylation presents distinct binding sites for human transcription factors. Elife (2013) 1.63
Vertical transmission of Zika virus targeting the radial glial cells affects cortex development of offspring mice. Cell Res (2016) 1.62
Congenital Zika Virus Infection: Beyond Neonatal Microcephaly. JAMA Neurol (2016) 1.59
Noncoding flavivirus RNA displays RNA interference suppressor activity in insect and Mammalian cells. J Virol (2012) 1.58
Adult Mammalian Neural Stem Cells and Neurogenesis: Five Decades Later. Cell Stem Cell (2015) 1.54
Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell-derived neocortex. Proc Natl Acad Sci U S A (2013) 1.53
Historical landmarks of autophagy research. Cell Res (2013) 1.49
Vaginal Exposure to Zika Virus during Pregnancy Leads to Fetal Brain Infection. Cell (2016) 1.47
Zika Virus Infects Human Placental Macrophages. Cell Host Microbe (2016) 1.45
Flavivirus NS4A-induced autophagy protects cells against death and enhances virus replication. J Biol Chem (2011) 1.45
Flavivirus capsid is a dimeric alpha-helical protein. J Virol (2003) 1.43
Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen. Nat Med (2016) 1.43
Isolation of infectious Zika virus from saliva and prolonged viral RNA shedding in a traveller returning from the Dominican Republic to Italy, January 2016. Euro Surveill (2016) 1.41
An Infectious cDNA Clone of Zika Virus to Study Viral Virulence, Mosquito Transmission, and Antiviral Inhibitors. Cell Host Microbe (2016) 1.35
Genetic causes of microcephaly and lessons for neuronal development. Wiley Interdiscip Rev Dev Biol (2012) 1.34
Modeling Development and Disease with Organoids. Cell (2016) 1.34
The Viral Polymerase Inhibitor 7-Deaza-2'-C-Methyladenosine Is a Potent Inhibitor of In Vitro Zika Virus Replication and Delays Disease Progression in a Robust Mouse Infection Model. PLoS Negl Trop Dis (2016) 1.30
RNA N6-methyladenosine methylation in post-transcriptional gene expression regulation. Genes Dev (2015) 1.29
Persistent detection of Zika virus RNA in semen for six months after symptom onset in a traveller returning from Haiti to Italy, February 2016. Euro Surveill (2016) 1.28
Zika Virus Infection in Mice Causes Panuveitis with Shedding of Virus in Tears. Cell Rep (2016) 1.25
Zika Virus Targets Human STAT2 to Inhibit Type I Interferon Signaling. Cell Host Microbe (2016) 1.25
Zika Virus Targets Different Primary Human Placental Cells, Suggesting Two Routes for Vertical Transmission. Cell Host Microbe (2016) 1.24
Replication of hepatitis C virus RNA on autophagosomal membranes. J Biol Chem (2012) 1.24
Association between Zika virus infection and microcephaly in Brazil, January to May, 2016: preliminary report of a case-control study. Lancet Infect Dis (2016) 1.23
Zika Virus Infects Neural Progenitors in the Adult Mouse Brain and Alters Proliferation. Cell Stem Cell (2016) 1.21
Influence of infection during pregnancy on fetal development. Reproduction (2013) 1.20
Quantitative single-cell approaches to stem cell research. Cell Stem Cell (2014) 1.17
Stem Cell Models of Human Brain Development. Cell Stem Cell (2016) 1.14
Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics. Cell Rep (2016) 1.13
Guillain-Barré syndrome associated with the Zika virus outbreak in Brazil. Arq Neuropsiquiatr (2016) 1.05
Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice. Nature (2016) 1.04
Fetal brain lesions after subcutaneous inoculation of Zika virus in a pregnant nonhuman primate. Nat Med (2016) 1.03
Zika virus - reigniting the TORCH. Nat Rev Microbiol (2016) 1.03
Zika Virus Strains Potentially Display Different Infectious Profiles in Human Neural Cells. EBioMedicine (2016) 1.02
Recent insights into the complexity of Tank-binding kinase 1 signaling networks: the emerging role of cellular localization in the activation and substrate specificity of TBK1. FEBS Lett (2013) 0.99
Expanded Spectrum of Congenital Ocular Findings in Microcephaly with Presumed Zika Infection. Ophthalmology (2016) 0.98
Molecular signatures associated with ZIKV exposure in human cortical neural progenitors. Nucleic Acids Res (2016) 0.98
Zika viral dynamics and shedding in rhesus and cynomolgus macaques. Nat Med (2016) 0.95
The IFITMs Inhibit Zika Virus Replication. Cell Rep (2016) 0.95
Zika virus in semen and spermatozoa. Lancet Infect Dis (2016) 0.95
Zika Virus NS4A and NS4B Proteins Deregulate Akt-mTOR Signaling in Human Fetal Neural Stem Cells to Inhibit Neurogenesis and Induce Autophagy. Cell Stem Cell (2016) 0.95
Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia. Cell Rep (2016) 0.93
Genetic dissection of Flaviviridae host factors through genome-scale CRISPR screens. Nature (2016) 0.92
Decoding neural transcriptomes and epigenomes via high-throughput sequencing. Nat Neurosci (2014) 0.91
ZIKA virus reveals broad tissue and cell tropism during the first trimester of pregnancy. Sci Rep (2016) 0.90
A complement-microglial axis drives synapse loss during virus-induced memory impairment. Nature (2016) 0.90
Zika Virus Infection Induces Cranial Neural Crest Cells to Produce Cytokines at Levels Detrimental for Neurogenesis. Cell Host Microbe (2016) 0.89
Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection. Immunity (2016) 0.89
Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure. Cell (2016) 3.33
Development of bivalent oleanane-type triterpenes as potent HCV entry inhibitors. Eur J Med Chem (2014) 0.75