Published in Cell on January 07, 2000
In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Genes Dev (2003) 20.77
Direct isolation of human central nervous system stem cells. Proc Natl Acad Sci U S A (2000) 10.88
MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis. Cell (2000) 8.00
Coexistence of quiescent and active adult stem cells in mammals. Science (2010) 7.54
c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation. Genes Dev (2004) 5.83
Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates. J Exp Med (2005) 5.68
Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells. Breast Cancer Res (2004) 5.60
Expression of CD34 and Myf5 defines the majority of quiescent adult skeletal muscle satellite cells. J Cell Biol (2000) 5.04
Identification of genes needed for regeneration, stem cell function, and tissue homeostasis by systematic gene perturbation in planaria. Dev Cell (2005) 4.35
HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway. J Clin Invest (2001) 4.11
Normal and leukemic hematopoiesis: are leukemias a stem cell disorder or a reacquisition of stem cell characteristics? Proc Natl Acad Sci U S A (2003) 4.09
mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells. Sci Signal (2009) 3.94
Tracking single hematopoietic stem cells in vivo using high-throughput sequencing in conjunction with viral genetic barcoding. Nat Biotechnol (2011) 3.81
Induction of the chemokine stromal-derived factor-1 following DNA damage improves human stem cell function. J Clin Invest (2000) 3.78
Clonogenic neoblasts are pluripotent adult stem cells that underlie planarian regeneration. Science (2011) 3.72
Genome-wide lineage-specific transcriptional networks underscore Ikaros-dependent lymphoid priming in hematopoietic stem cells. Immunity (2009) 3.18
Clonal dynamics of native haematopoiesis. Nature (2014) 3.15
The emergence of hematopoietic stem cells is initiated in the placental vasculature in the absence of circulation. Cell Stem Cell (2008) 3.09
Molecular regulation of stem cell quiescence. Nat Rev Mol Cell Biol (2013) 3.07
Germ-layer and lineage-restricted stem/progenitors regenerate the mouse digit tip. Nature (2011) 3.03
Intrarenal cells, not bone marrow-derived cells, are the major source for regeneration in postischemic kidney. J Clin Invest (2005) 2.94
Paths to stemness: building the ultimate antitumour T cell. Nat Rev Cancer (2012) 2.79
Molecular analysis of stem cells and their descendants during cell turnover and regeneration in the planarian Schmidtea mediterranea. Cell Stem Cell (2008) 2.73
Alternative splicing events identified in human embryonic stem cells and neural progenitors. PLoS Comput Biol (2007) 2.71
From hematopoiesis to neuropoiesis: evidence of overlapping genetic programs. Proc Natl Acad Sci U S A (2001) 2.66
Epidermal stem cells: properties, markers, and location. Proc Natl Acad Sci U S A (2000) 2.66
Transcription factor Gfi1 regulates self-renewal and engraftment of hematopoietic stem cells. EMBO J (2004) 2.57
Building muscle: molecular regulation of myogenesis. Cold Spring Harb Perspect Biol (2012) 2.52
Establishing the transcriptional programme for blood: the SCL stem cell enhancer is regulated by a multiprotein complex containing Ets and GATA factors. EMBO J (2002) 2.40
Lifespan extension by preserving proliferative homeostasis in Drosophila. PLoS Genet (2010) 2.39
Asymmetric division and lineage commitment at the level of hematopoietic stem cells: inference from differentiation in daughter cell and granddaughter cell pairs. J Exp Med (2004) 2.31
The elusive nature and function of mesenchymal stem cells. Nat Rev Mol Cell Biol (2011) 2.31
Circulation and chemotaxis of fetal hematopoietic stem cells. PLoS Biol (2004) 2.18
Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development. Proc Natl Acad Sci U S A (2007) 2.15
Isolation of a novel population of multipotent adult stem cells from human hair follicles. Am J Pathol (2006) 2.13
Ex vivo expansion of human hematopoietic stem and progenitor cells. Blood (2011) 2.12
The impact of altered p53 dosage on hematopoietic stem cell dynamics during aging. Blood (2006) 2.10
Age-related changes in Drosophila midgut are associated with PVF2, a PDGF/VEGF-like growth factor. Aging Cell (2008) 2.09
Fundamental properties of unperturbed haematopoiesis from stem cells in vivo. Nature (2015) 2.06
Genetic regulators of a pluripotent adult stem cell system in planarians identified by RNAi and clonal analysis. Cell Stem Cell (2012) 2.03
Adipose tissue stem cells meet preadipocyte commitment: going back to the future. J Lipid Res (2011) 1.94
Manifestations and mechanisms of stem cell aging. J Cell Biol (2011) 1.93
Cancer predisposition and hematopoietic failure in Rad50(S/S) mice. Genes Dev (2002) 1.87
The role of the chromatin remodeler Mi-2beta in hematopoietic stem cell self-renewal and multilineage differentiation. Genes Dev (2008) 1.82
Hematopoietic stem cells need two signals to prevent apoptosis; BCL-2 can provide one of these, Kitl/c-Kit signaling the other. J Exp Med (2000) 1.78
Therapeutic potential of vasculogenesis and osteogenesis promoted by peripheral blood CD34-positive cells for functional bone healing. Am J Pathol (2006) 1.75
AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species. Blood (2010) 1.75
Diet controls normal and tumorous germline stem cells via insulin-dependent and -independent mechanisms in Drosophila. Dev Biol (2007) 1.74
Normal and neoplastic urothelial stem cells: getting to the root of the problem. Nat Rev Urol (2012) 1.73
Wnt-5A augments repopulating capacity and primitive hematopoietic development of human blood stem cells in vivo. Proc Natl Acad Sci U S A (2003) 1.72
Drug discovery approaches to target Wnt signaling in cancer stem cells. Oncotarget (2010) 1.71
Myogenic stem cell function is impaired in mice lacking the forkhead/winged helix protein MNF. Proc Natl Acad Sci U S A (2000) 1.68
Fgd5 identifies hematopoietic stem cells in the murine bone marrow. J Exp Med (2014) 1.62
Repeated, long-term cycling of putative stem cells between niches in a basal chordate. Dev Cell (2012) 1.62
Maintenance of hematopoietic stem cells through regulation of Wnt and mTOR pathways. Nat Med (2012) 1.58
Defective gene expression, S phase progression, and maturation during hematopoiesis in E2F1/E2F2 mutant mice. Mol Cell Biol (2003) 1.56
Stem cell systems and regeneration in planaria. Dev Genes Evol (2012) 1.51
Molecular signatures of quiescent, mobilized and leukemia-initiating hematopoietic stem cells. PLoS One (2010) 1.46
Extracellular matrix: a dynamic microenvironment for stem cell niche. Biochim Biophys Acta (2014) 1.45
GPI-80 defines self-renewal ability in hematopoietic stem cells during human development. Cell Stem Cell (2014) 1.42
Targeting metabolic remodeling in glioblastoma multiforme. Oncotarget (2010) 1.42
Differential long-term and multilineage engraftment potential from subfractions of human CD34+ cord blood cells transplanted into NOD/SCID mice. Proc Natl Acad Sci U S A (2002) 1.41
DNA repair is crucial for maintaining hematopoietic stem cell function. DNA Repair (Amst) (2008) 1.40
The spreading, migration and proliferation of mouse mesenchymal stem cells cultured inside hyaluronic acid hydrogels. Biomaterials (2010) 1.40
Brain regeneration in physiology and pathology: the immune signature driving therapeutic plasticity of neural stem cells. Physiol Rev (2011) 1.40
Hematopoietic stem cell aging: mechanism and consequence. Exp Gerontol (2007) 1.39
Stem cells, cell transplantation and liver repopulation. Biochim Biophys Acta (2007) 1.37
Role for FGFR2IIIb-mediated signals in controlling pancreatic endocrine progenitor cell proliferation. Proc Natl Acad Sci U S A (2002) 1.36
Concise review: Bone marrow for the treatment of spinal cord injury: mechanisms and clinical applications. Stem Cells (2011) 1.34
Uncoupling p53 functions in radiation-induced intestinal damage via PUMA and p21. Mol Cancer Res (2011) 1.34
A review of gene and stem cell therapy in cutaneous wound healing. Burns (2008) 1.34
Vaccinia virus infection modulates the hematopoietic cell compartments in the bone marrow. Stem Cells (2008) 1.33
Bone marrow mesenchymal stem cells from infants with MLL-AF4+ acute leukemia harbor and express the MLL-AF4 fusion gene. J Exp Med (2009) 1.31
Olig2+ neuroepithelial motoneuron progenitors are not multipotent stem cells in vivo. Proc Natl Acad Sci U S A (2006) 1.30
Distinct functions for different scl isoforms in zebrafish primitive and definitive hematopoiesis. PLoS Biol (2007) 1.29
Hepatic stem cell niches. J Clin Invest (2013) 1.29
Empowering adult stem cells for myocardial regeneration. Circ Res (2011) 1.25
Concise review: Kidney stem/progenitor cells: differentiate, sort out, or reprogram? Stem Cells (2010) 1.23
Mice cloned from skin cells. Proc Natl Acad Sci U S A (2007) 1.23
Superparamagnetic iron oxide nanoparticles labeling of bone marrow stromal (mesenchymal) cells does not affect their "stemness". PLoS One (2010) 1.20
A curriculum vitae of teeth: evolution, generation, regeneration. Int J Biol Sci (2009) 1.19
Inactivation of the polycomb group protein Ring1B unveils an antiproliferative role in hematopoietic cell expansion and cooperation with tumorigenesis associated with Ink4a deletion. Mol Cell Biol (2007) 1.19
Adipogenic potential of adipose stem cell subpopulations. Plast Reconstr Surg (2011) 1.19
Animal cell differentiation patterns suppress somatic evolution. PLoS Comput Biol (2007) 1.19
Independent stem cell lineages regulate adipose organogenesis and adipose homeostasis. Cell Rep (2014) 1.18
Effect of cellular quiescence on the success of targeted CML therapy. PLoS One (2007) 1.18
Human endometrial side population cells exhibit genotypic, phenotypic and functional features of somatic stem cells. PLoS One (2010) 1.17
Developmental and regenerative biology of multipotent cardiovascular progenitor cells. Circ Res (2011) 1.16
Fate of bone marrow stem cells transplanted into the testis: potential implication for men with testicular failure. Am J Pathol (2007) 1.14
Cell lineage analysis of the mammalian female germline. PLoS Genet (2012) 1.13
Existing cardiomyocytes generate cardiomyocytes at a low rate after birth in mice. Proc Natl Acad Sci U S A (2014) 1.12
Heterozygous kit mutants with little or no apparent anemia exhibit large defects in overall hematopoietic stem cell function. Exp Hematol (2007) 1.12
Emerging role of circulating calcifying cells in the bone-vascular axis. Circulation (2012) 1.11
Epigenetic modulation of miR-122 facilitates human embryonic stem cell self-renewal and hepatocellular carcinoma proliferation. PLoS One (2011) 1.11
High frequency of cephalic neural crest cells shows coexistence of neurogenic, melanogenic, and osteogenic differentiation capacities. Proc Natl Acad Sci U S A (2009) 1.06
Adipose tissue-derived mesenchymal stem cells facilitate hematopoiesis in vitro and in vivo: advantages over bone marrow-derived mesenchymal stem cells. Am J Pathol (2010) 1.06
Enforced Bcl-2 expression overrides serum and feeder cell requirements for mouse embryonic stem cell self-renewal. Proc Natl Acad Sci U S A (2005) 1.06
Identification of the endostyle as a stem cell niche in a colonial chordate. Cell Stem Cell (2008) 1.04
Factors and networks that underpin early hematopoiesis. Semin Immunol (2011) 1.03
Transdetermination: Drosophila imaginal disc cells exhibit stem cell-like potency. Int J Biochem Cell Biol (2007) 1.02