Exploring experimental cerebral malaria pathogenesis through the characterisation of host-derived plasma microparticle protein content.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 27917875)

Published in Sci Rep on December 05, 2016

Authors

Natalia Tiberti1,2, Sharissa L Latham2, Stephen Bush3, Amy Cohen2, Robert O Opoka4, Chandy C John5,6, Annette Juillard2, Georges E Grau2,7, Valéry Combes1,2,7

Author Affiliations

1: School of Life Sciences, Faculty of Sciences, University of Technology Sydney, Australia.
2: Vascular Immunology Unit, Department of Pathology, The University of Sydney, Australia.
3: School of Mathematical and Physical Sciences, University of Technology Sydney, Australia.
4: College of Health Sciences, Makerere University, Kampala, Uganda.
5: Indiana University School of Medicine, Indianapolis, United States of America.
6: University of Minnesota, Minneapolis, United States of America.
7: La Jolla Infectious Diseases Institute, San Diego, CA, United States of America.

Articles citing this

Cytokines and Chemokines in Cerebral Malaria Pathogenesis. Front Cell Infect Microbiol (2017) 0.75

Articles cited by this

ProteomeXchange provides globally coordinated proteomics data submission and dissemination. Nat Biotechnol (2014) 13.40

The PRoteomics IDEntifications (PRIDE) database and associated tools: status in 2013. Nucleic Acids Res (2012) 13.14

Detection of microRNA expression in human peripheral blood microvesicles. PLoS One (2008) 8.04

Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation. Blood (2005) 3.85

Basigin is a receptor essential for erythrocyte invasion by Plasmodium falciparum. Nature (2011) 3.83

Protein identification at the low femtomole level from silver-stained gels using a new fritless electrospray interface for liquid chromatography-microspray and nanospray mass spectrometry. Anal Biochem (1998) 3.76

S100A8 and S100A9 in inflammation and cancer. Biochem Pharmacol (2006) 3.67

Blantyre Malaria Project Epilepsy Study (BMPES) of neurological outcomes in retinopathy-positive paediatric cerebral malaria survivors: a prospective cohort study. Lancet Neurol (2010) 3.47

Microparticles: protagonists of a novel communication network for intercellular information exchange. Circ Res (2010) 3.03

Myeloid-related protein (MRP) 8 and MRP14, calcium-binding proteins of the S100 family, are secreted by activated monocytes via a novel, tubulin-dependent pathway. J Biol Chem (1997) 2.57

Malaria-infected erythrocyte-derived microvesicles mediate cellular communication within the parasite population and with the host immune system. Cell Host Microbe (2013) 2.29

High plasma erythropoietin levels are associated with prolonged coma duration and increased mortality in children with cerebral malaria. Clin Infect Dis (2014) 2.02

Cerebral malaria: mechanisms of brain injury and strategies for improved neurocognitive outcome. Pediatr Res (2010) 1.98

Myeloid-related proteins 8 and 14 are specifically secreted during interaction of phagocytes and activated endothelium and are useful markers for monitoring disease activity in pauciarticular-onset juvenile rheumatoid arthritis. Arthritis Rheum (2000) 1.95

Myeloid-related proteins 8 and 14 induce a specific inflammatory response in human microvascular endothelial cells. Blood (2004) 1.85

Cerebral malaria: the contribution of studies in animal models to our understanding of immunopathogenesis. Microbes Infect (2002) 1.81

Microvesicles as cell-cell messengers in cardiovascular diseases. Circ Res (2014) 1.68

Inflammation-associated S100 proteins: new mechanisms that regulate function. Amino Acids (2010) 1.65

Microparticles as regulators of inflammation: novel players of cellular crosstalk in the rheumatic diseases. Arthritis Rheum (2005) 1.64

Circulating endothelial microparticles in malawian children with severe falciparum malaria complicated with coma. JAMA (2004) 1.60

Proteomics of microparticles after deep venous thrombosis. Thromb Res (2010) 1.50

Microparticles: biomarkers and beyond. Clin Sci (Lond) (2013) 1.41

A novel role for von Willebrand factor in the pathogenesis of experimental cerebral malaria. Blood (2015) 1.40

Circulating red cell-derived microparticles in human malaria. J Infect Dis (2011) 1.30

The prognostic value of measures of acid/base balance in pediatric falciparum malaria, compared with other clinical and laboratory parameters. Clin Infect Dis (2005) 1.30

Tumor necrosis factor alpha in the pathogenesis of cerebral malaria. Cell Mol Life Sci (2003) 1.29

Cerebral malaria: role of microparticles and platelets in alterations of the blood-brain barrier. Int J Parasitol (2006) 1.29

The multifunctional S100 protein family. Methods Mol Biol (2002) 1.24

TGF-beta1 released from activated platelets can induce TNF-stimulated human brain endothelium apoptosis: a new mechanism for microvascular lesion during cerebral malaria. J Immunol (2006) 1.22

S100A8 and S100A9: new insights into their roles in malignancy. J Innate Immun (2011) 1.20

EasyProt--an easy-to-use graphical platform for proteomics data analysis. J Proteomics (2012) 1.20

Aquaporin 9 is the major pathway for glycerol uptake by mouse erythrocytes, with implications for malarial virulence. Proc Natl Acad Sci U S A (2007) 1.18

Elevated cell-specific microparticles are a biological marker for cerebral dysfunctions in human severe malaria. PLoS One (2010) 1.17

Vascular endothelial cells cultured from patients with cerebral or uncomplicated malaria exhibit differential reactivity to TNF. Cell Microbiol (2010) 1.15

Circulating microparticles: square the circle. BMC Cell Biol (2013) 1.14

ABCA1 gene deletion protects against cerebral malaria: potential pathogenic role of microparticles in neuropathology. Am J Pathol (2005) 1.12

Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections. PLoS One (2011) 1.10

The roles of extracellular vesicles in cancer biology: toward the development of novel cancer biomarkers. Proteomics (2014) 1.10

"Asymptomatic" Malaria: A Chronic and Debilitating Infection That Should Be Treated. PLoS Med (2016) 1.09

Elevated serum levels of calcium-binding S100 proteins A8 and A9 reflect disease activity and abnormal differentiation of keratinocytes in psoriasis. Br J Dermatol (2006) 1.07

Pathogenesis of cerebral malaria--inflammation and cytoadherence. Front Cell Infect Microbiol (2014) 1.06

Protection against cerebral malaria by the low-molecular-weight thiol pantethine. Proc Natl Acad Sci U S A (2008) 1.04

The mouse carbonic anhydrase I gene contains two tissue-specific promoters. Mol Cell Biol (1989) 1.03

Discovery and verification of osteopontin and Beta-2-microglobulin as promising markers for staging human African trypanosomiasis. Mol Cell Proteomics (2010) 1.02

Microvesiculation and cell interactions at the brain-endothelial interface in cerebral malaria pathogenesis. Prog Neurobiol (2010) 1.02

Gene network and canonical pathway analysis in prostate cancer: a microarray study. Exp Mol Med (2008) 1.01

Endothelial activation and dysregulation in malaria: a potential target for novel therapeutics. Curr Opin Hematol (2011) 0.99

Real-time imaging reveals the dynamics of leukocyte behaviour during experimental cerebral malaria pathogenesis. PLoS Pathog (2014) 0.98

Experimental cerebral malaria pathogenesis--hemodynamics at the blood brain barrier. PLoS Pathog (2014) 0.97

Malaria: modification of the red blood cell and consequences in the human host. Br J Haematol (2011) 0.96

Investigating the Pathogenesis of Severe Malaria: A Multidisciplinary and Cross-Geographical Approach. Am J Trop Med Hyg (2015) 0.96

The plasma microparticle proteome. Semin Thromb Hemost (2010) 0.94

Affinity proteomics reveals elevated muscle proteins in plasma of children with cerebral malaria. PLoS Pathog (2014) 0.94

Cooperation between β- and γ-cytoplasmic actins in the mechanical regulation of endothelial microparticle formation. FASEB J (2012) 0.94

Persistent endothelial activation and inflammation after Plasmodium falciparum Infection in Malawian children. J Infect Dis (2013) 0.91

Amplification of P. falciparum Cytoadherence through induction of a pro-adhesive state in host endothelium. PLoS One (2011) 0.89

Microparticles are novel effectors of immunity. Curr Opin Pharmacol (2013) 0.88

Quantitative proteome profiling of normal human circulating microparticles. J Proteome Res (2012) 0.87

MRP 8/14 as marker for Plasmodium falciparum-induced malaria episodes in individuals in a holoendemic area. Clin Diagn Lab Immunol (1997) 0.83

Mild Plasmodium falciparum malaria following an episode of severe malaria is associated with induction of the interferon pathway in Malawian children. Infect Immun (2012) 0.83

Cerebral tissue oxygenation impairment during experimental cerebral malaria. Virulence (2013) 0.83

Microparticles: a new perspective in central nervous system disorders. Biomed Res Int (2014) 0.82

Characterization of secreted vesicles from vascular smooth muscle cells. Mol Biosyst (2014) 0.81

Production, fate and pathogenicity of plasma microparticles in murine cerebral malaria. PLoS Pathog (2014) 0.81

Endothelial microparticles interact with and support the proliferation of T cells. J Immunol (2014) 0.80

Lipoxin A4 attenuates endothelial dysfunction during experimental cerebral malaria. Int Immunopharmacol (2015) 0.79

Gene network analysis shows immune-signaling and ERK1/2 as novel genetic markers for multiple addiction phenotypes: alcohol, smoking and opioid addiction. BMC Syst Biol (2015) 0.78

Microparticles in cancer: A review of recent developments and the potential for clinical application. Semin Cell Dev Biol (2015) 0.78

Mass spectrometry of extracellular vesicles. Mass Spectrom Rev (2015) 0.78

The role of carbonic anhydrase in the pathogenesis of vascular calcification in humans. Atherosclerosis (2015) 0.77

The accumulation of macrophages expressing myeloid-related protein 8 (MRP8) and MRP14 in the spleen of BALB/cA mice during infection with Plasmodium berghei. Exp Parasitol (2014) 0.77

Treatment of erythrocytes with the 2-cys peroxiredoxin inhibitor, Conoidin A, prevents the growth of Plasmodium falciparum and enhances parasite sensitivity to chloroquine. PLoS One (2014) 0.77