Published in J Biol Chem on April 04, 1997
Neutrophil extracellular traps contain calprotectin, a cytosolic protein complex involved in host defense against Candida albicans. PLoS Pathog (2009) 5.40
Vascular and inflammatory stresses mediate atherosclerosis via RAGE and its ligands in apoE-/- mice. J Clin Invest (2008) 3.11
Central role of RAGE-dependent neointimal expansion in arterial restenosis. J Clin Invest (2003) 2.40
Neutrophil derived human S100A12 (EN-RAGE) is strongly expressed during chronic active inflammatory bowel disease. Gut (2003) 2.39
In vivo regulation of interleukin 1beta in patients with cryopyrin-associated periodic syndromes. J Exp Med (2009) 2.34
DNA methylation in inflammatory genes among children with obstructive sleep apnea. Am J Respir Crit Care Med (2011) 1.92
Myeloid cell function in MRP-14 (S100A9) null mice. Mol Cell Biol (2003) 1.76
The S100A8/A9 heterodimer amplifies proinflammatory cytokine production by macrophages via activation of nuclear factor kappa B and p38 mitogen-activated protein kinase in rheumatoid arthritis. Arthritis Res Ther (2006) 1.67
Endogenous damage-associated molecular pattern molecules at the crossroads of inflammation and cancer. Neoplasia (2009) 1.66
Molecular basis for manganese sequestration by calprotectin and roles in the innate immune response to invading bacterial pathogens. Proc Natl Acad Sci U S A (2013) 1.64
Protein S100A4: too long overlooked by pathologists? Am J Pathol (2002) 1.59
Increased proinflammatory endothelial response to S100A8/A9 after preactivation through advanced glycation end products. Cardiovasc Diabetol (2006) 1.40
S100A12 mediates aortic wall remodeling and aortic aneurysm. Circ Res (2009) 1.36
S100A12 in vascular smooth muscle accelerates vascular calcification in apolipoprotein E-null mice by activating an osteogenic gene regulatory program. Arterioscler Thromb Vasc Biol (2010) 1.32
Complexity of danger: the diverse nature of damage-associated molecular patterns. J Biol Chem (2014) 1.32
S100A8 and S100A9 in cardiovascular biology and disease. Arterioscler Thromb Vasc Biol (2011) 1.27
ANTI-INFECTIVE PROTECTIVE PROPERTIES OF S100 CALGRANULINS. Antiinflamm Antiallergy Agents Med Chem (2009) 1.26
Calprotectin expression by gingival epithelial cells. Infect Immun (2001) 1.22
S100A9 differentially modifies phenotypic states of neutrophils, macrophages, and dendritic cells: implications for atherosclerosis and adipose tissue inflammation. Circulation (2011) 1.20
S100A8 and S100A9: new insights into their roles in malignancy. J Innate Immun (2011) 1.20
Myeloid-related protein-14 contributes to protective immunity in gram-negative pneumonia derived sepsis. PLoS Pathog (2012) 1.19
Endothelial dysfunction in children without hypertension: potential contributions of obesity and obstructive sleep apnea. Chest (2011) 1.17
Identification of human epidermal differentiation complex (EDC)-encoded genes by subtractive hybridization of entire YACs to a gridded keratinocyte cDNA library. Genome Res (2001) 1.16
Chaperonin 60 unfolds its secrets of cellular communication. Cell Stress Chaperones (2002) 1.14
Calprotectin expression inhibits bacterial binding to mucosal epithelial cells. Infect Immun (2001) 1.14
Staphylococcus aureus Panton-Valentine leukocidin induces an inflammatory response in human phagocytes via the NLRP3 inflammasome. J Leukoc Biol (2012) 1.11
Pro-inflammatory S100A8 and S100A9 proteins: self-assembly into multifunctional native and amyloid complexes. Int J Mol Sci (2012) 1.09
Platelet-derived S100 family member myeloid-related protein-14 regulates thrombosis. J Clin Invest (2014) 1.06
Calprotectin is released from human skeletal muscle tissue during exercise. J Physiol (2008) 1.03
Interleukin-7 stimulates secretion of S100A4 by activating the JAK/STAT signaling pathway in human articular chondrocytes. Arthritis Rheum (2009) 1.03
Expression of calcium-binding proteins MRP8 and MRP14 in inflammatory muscle diseases. Am J Pathol (2003) 1.02
Calprotectin S100A9 calcium-binding loops I and II are essential for keratinocyte resistance to bacterial invasion. J Biol Chem (2009) 1.01
Vascular remodeling and arterial calcification are directly mediated by S100A12 (EN-RAGE) in chronic kidney disease. Am J Nephrol (2011) 0.99
Interleukin-6 induces S100A9 expression in colonic epithelial cells through STAT3 activation in experimental ulcerative colitis. PLoS One (2012) 0.98
S100A8 triggers oxidation-sensitive repulsion of neutrophils. J Dent Res (2006) 0.98
Novel insights into the role of S100A8/A9 in skin biology. Exp Dermatol (2012) 0.98
Understanding Haemophilus parasuis infection in porcine spleen through a transcriptomics approach. BMC Genomics (2009) 0.96
An increased MRP8/14 expression and adhesion, but a decreased migration towards proinflammatory chemokines of type 1 diabetes monocytes. Clin Exp Immunol (2005) 0.96
Nutritional Immunity: S100 Proteins at the Host-Pathogen Interface. J Biol Chem (2015) 0.95
Increased levels of calprotectin in obesity are related to macrophage content: impact on inflammation and effect of weight loss. Mol Med (2011) 0.94
S-glutathionylation regulates inflammatory activities of S100A9. J Biol Chem (2010) 0.93
Alarmin S100A8/S100A9 as a biomarker for molecular imaging of local inflammatory activity. Nat Commun (2014) 0.93
TREM-1 and pentraxin-3 plasma levels and their association with obstructive sleep apnea, obesity, and endothelial function in children. Sleep (2013) 0.91
Identification of poly(ADP-ribose)polymerase-1 and Ku70/Ku80 as transcriptional regulators of S100A9 gene expression. BMC Mol Biol (2006) 0.91
Interleukin-4 (IL-4) and IL-13 suppress excessive neutrophil infiltration and hepatocyte damage during acute murine schistosomiasis japonica. Infect Immun (2011) 0.91
Inflammatory response in patients with active and inactive osteoarthritis. Rheumatol Int (2009) 0.90
Functional characterization of S100A8 and S100A9 in altering monolayer permeability of human umbilical endothelial cells. PLoS One (2014) 0.90
HMGB1, IL-1α, IL-33 and S100 proteins: dual-function alarmins. Cell Mol Immunol (2016) 0.89
IL-1 receptor regulates S100A8/A9-dependent keratinocyte resistance to bacterial invasion. Mucosal Immunol (2011) 0.89
DAMPs activating innate and adaptive immune responses in COPD. Mucosal Immunol (2013) 0.89
Calprotectin: a novel noninvasive marker for intestinal allograft monitoring. Ann Surg (2007) 0.88
Myeloid related protein 8 and 14 secretion reflects phagocyte activation and correlates with disease activity in juvenile idiopathic arthritis treated with autologous stem cell transplantation. Ann Rheum Dis (2003) 0.88
MRP8 and MRP14, phagocyte-specific danger signals, are sensitive biomarkers of disease activity in cryopyrin-associated periodic syndromes. Ann Rheum Dis (2011) 0.88
Transgenic expression of human S100A12 induces structural airway abnormalities and limited lung inflammation in a mouse model of allergic inflammation. Clin Exp Allergy (2011) 0.86
12-O-tetradecanoylphorbol-13-acetate promotes breast cancer cell motility by increasing S100A14 level in a Kruppel-like transcription factor 4 (KLF4)-dependent manner. J Biol Chem (2014) 0.86
Injury-induced MRP8/MRP14 stimulates IP-10/CXCL10 in monocytes/macrophages. FASEB J (2014) 0.86
New insights into the regulation of neutrophil NADPH oxidase activity in the phagosome: a focus on the role of lipid and Ca(2+) signaling. Antioxid Redox Signal (2012) 0.85
In vivo targeting of inflammation-associated myeloid-related protein 8/14 via gadolinium immunonanoparticles. Arterioscler Thromb Vasc Biol (2012) 0.85
The subcellular distribution of myeloid-related protein 8 (MRP8) and MRP14 in human neutrophils. J Transl Med (2005) 0.85
Zinc and Manganese Chelation by Neutrophil S100A8/A9 (Calprotectin) Limits Extracellular Aspergillus fumigatus Hyphal Growth and Corneal Infection. J Immunol (2015) 0.84
Manganese homeostasis and utilization in pathogenic bacteria. Mol Microbiol (2015) 0.84
Nitrosothiols in the immune system: signaling and protection. Antioxid Redox Signal (2012) 0.84
Local calprotectin production in colorectal cancer and polyps--active neutrophil recruitment in carcinogenesis. Int J Colorectal Dis (2011) 0.84
Suppression of inflammation in rat autoimmune myocarditis by S100A8/A9 through modulation of the proinflammatory cytokine network. Eur J Heart Fail (2009) 0.84
Reaction patterns of pulmonary macrophages in protracted asphyxiation. Int J Legal Med (2010) 0.84
The alarmin Mrp8/14 as regulator of the adaptive immune response during allergic contact dermatitis. EMBO J (2012) 0.83
Neutrophils and the calcium-binding protein MRP-14 mediate carrageenan-induced antinociception in mice. Mediators Inflamm (2002) 0.83
Myeloid-related protein 8/14 complex describes microcirculatory alterations in patients with type 2 diabetes and nephropathy. Cardiovasc Diabetol (2009) 0.83
Neutrophil-to-lymphocyte ratio, calprotectin and YKL-40 in patients with chronic obstructive pulmonary disease: correlations and 5-year mortality - a cohort study. J Inflamm (Lond) (2015) 0.82
Proteomic analysis of stromal proteins in different stages of colorectal cancer establishes Tenascin-C as a stromal biomarker for colorectal cancer metastasis. Oncotarget (2016) 0.81
DAMPs, ageing, and cancer: The 'DAMP Hypothesis'. Ageing Res Rev (2014) 0.81
Eritoran inhibits S100A8-mediated TLR4/MD-2 activation and tumor growth by changing the immune microenvironment. Oncogene (2015) 0.81
Role of Staphylococcus aureus Virulence Factors in Inducing Inflammation and Vascular Permeability in a Mouse Model of Bacterial Endophthalmitis. PLoS One (2015) 0.80
Molecular interface of S100A8 with cytochrome b558 and NADPH oxidase activation. PLoS One (2012) 0.80
High expression of myeloid-related proteins 8 and 14 characterizes an inflammatorily active but ineffective response of macrophages during leprosy. Immunology (2004) 0.80
S100A8/A9 as a biomarker for synovial inflammation and joint damage in patients with rheumatoid arthritis. Korean J Intern Med (2014) 0.79
Dynamic mobility of immunological cells expressing S100A8 and S100A9 in vivo: a variety of functional roles of the two proteins as regulators in acute inflammatory reaction. Inflammation (2012) 0.79
Comparative Proteomic Analysis of Two Uveitis Models in Lewis Rats. Invest Ophthalmol Vis Sci (2015) 0.79
Dicalcin inhibits fertilization through its binding to a glycoprotein in the egg envelope in Xenopus laevis. J Biol Chem (2010) 0.79
Fecal calprotectin: its scope and utility in the management of inflammatory bowel disease. J Gastroenterol (2016) 0.79
S100A8/A9 mRNA induction in an ex vivo model of endotoxin tolerance: roles of IL-10 and IFNγ. PLoS One (2014) 0.78
The pro-apoptotic and pro-inflammatory effects of calprotectin on human periodontal ligament cells. PLoS One (2014) 0.78
Fecal calprotectin concentrations in healthy children aged 1-18 months. PLoS One (2015) 0.78
Amyloid-β peptide-induced extracellular S100A9 depletion is associated with decrease of antimicrobial peptide activity in human THP-1 monocytes. J Neuroinflammation (2013) 0.77
Determination of leukotriene A(4) stabilization by S100A8/A9 proteins using mass spectrometry. J Lipid Res (2009) 0.77
Neutrophilic cell-free exudate induces antinociception mediate by the protein S100A9. Mediators Inflamm (2006) 0.76
The elevated serum S100A8/A9 during acute myocardial infarction is not of cardiac myocyte origin. Inflammation (2012) 0.76
S100A8/A9 stimulates keratinocyte proliferation in the development of squamous cell carcinoma of the skin via the receptor for advanced glycation-end products. PLoS One (2015) 0.76
Myeloid-related protein activity in rheumatoid arthritis. Int J Inflam (2011) 0.76
Redox distress and genetic defects conspire in systemic autoinflammatory diseases. Nat Rev Rheumatol (2015) 0.76
Buprenorphine decreases the CCL2-mediated chemotactic response of monocytes. J Immunol (2015) 0.76
CD14 Is a Co-Receptor for TLR4 in the S100A9-Induced Pro-Inflammatory Response in Monocytes. PLoS One (2016) 0.75
Rhazes viewpoints about causes, diagnosis, treatment and prognosis of gout. J Med Ethics Hist Med (2012) 0.75
Myeloid-related protein 8 induces self-tolerance and cross-tolerance to bacterial infection via TLR4- and TLR2-mediated signal pathways. Sci Rep (2015) 0.75
Immunohistochemical Characterization of S100A6 in the Murine Ovary. Acta Histochem Cytochem (2011) 0.75
Interleukin-8 transcripts in mononuclear cells determine impaired graft function after kidney transplantation. PLoS One (2015) 0.75
Crystal structure of human S100A8 in complex with zinc and calcium. BMC Struct Biol (2016) 0.75
Secretion of S100A8, S100A9, and S100A12 by Neutrophils Involves Reactive Oxygen Species and Potassium Efflux. J Immunol Res (2015) 0.75
Calprotectin in rheumatic diseases. Exp Biol Med (Maywood) (2016) 0.75
Exploring experimental cerebral malaria pathogenesis through the characterisation of host-derived plasma microparticle protein content. Sci Rep (2016) 0.75
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