Published in Nucleic Acids Res on April 20, 2017
Super-Enhancer-Driven Transcriptional Dependencies in Cancer. Trends Cancer (2017) 0.75
Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res (2002) 76.95
BEDTools: a flexible suite of utilities for comparing genomic features. Bioinformatics (2010) 53.23
Model-based analysis of ChIP-Seq (MACS). Genome Biol (2008) 51.63
Java Treeview--extensible visualization of microarray data. Bioinformatics (2004) 24.12
Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol Cell (2010) 23.97
The transcriptional coactivators p300 and CBP are histone acetyltransferases. Cell (1996) 16.57
Mediator and cohesin connect gene expression and chromatin architecture. Nature (2010) 14.34
Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1. Cell (2005) 14.32
FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription. Cell (2008) 14.18
Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription. Cell (2000) 11.10
A human cell line from a pleural effusion derived from a breast carcinoma. J Natl Cancer Inst (1973) 10.64
Master transcription factors and mediator establish super-enhancers at key cell identity genes. Cell (2013) 9.55
Selective inhibition of tumor oncogenes by disruption of super-enhancers. Cell (2013) 8.37
Super-enhancers in the control of cell identity and disease. Cell (2013) 7.50
The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer. Cell (1988) 6.59
ChIP-Seq of ERalpha and RNA polymerase II defines genes differentially responding to ligands. EMBO J (2009) 5.36
FOXA1 is a key determinant of estrogen receptor function and endocrine response. Nat Genet (2010) 5.22
An estrogen-responsive element derived from the 5' flanking region of the Xenopus vitellogenin A2 gene functions in transfected human cells. Cell (1986) 5.22
Histone recognition and large-scale structural analysis of the human bromodomain family. Cell (2012) 5.15
The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation. Nat Rev Genet (2010) 4.46
Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation. Nature (2013) 3.93
A CTCF-independent role for cohesin in tissue-specific transcription. Genome Res (2010) 3.89
Latent enhancers activated by stimulation in differentiated cells. Cell (2013) 3.44
Oncogene regulation. An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element. Science (2014) 2.91
NF-κB directs dynamic super enhancer formation in inflammation and atherogenesis. Mol Cell (2014) 2.62
MCF-7: the first hormone-responsive breast cancer cell line. Cancer Res (1997) 2.12
Estrogen receptor target gene: an evolving concept. Mol Endocrinol (2006) 2.09
Integrative model of genomic factors for determining binding site selection by estrogen receptor-α. Mol Syst Biol (2010) 2.04
Differential DNase I hypersensitivity reveals factor-dependent chromatin dynamics. Genome Res (2012) 1.85
On the detection and refinement of transcription factor binding sites using ChIP-Seq data. Nucleic Acids Res (2010) 1.67
AP-2γ regulates oestrogen receptor-mediated long-range chromatin interaction and gene transcription. EMBO J (2011) 1.49
Transcription factor cooperativity in early adipogenic hotspots and super-enhancers. Cell Rep (2014) 1.42
Mouse regulatory DNA landscapes reveal global principles of cis-regulatory evolution. Science (2014) 1.34
Thyroid hormone-induced juxtaposition of regulatory elements/factors and chromatin remodeling of Crabp1 dependent on MED1/TRAP220. Mol Cell (2005) 1.30
The Mediator complex: a master coordinator of transcription and cell lineage development. Development (2014) 1.23
Multiplatform genome-wide identification and modeling of functional human estrogen receptor binding sites. Genome Biol (2006) 1.17
Control of embryonic stem cell identity by BRD4-dependent transcriptional elongation of super-enhancer-associated pluripotency genes. Cell Rep (2014) 1.14
Master regulators of FGFR2 signalling and breast cancer risk. Nat Commun (2013) 1.12
Targeting Myc in KSHV-associated primary effusion lymphoma with BET bromodomain inhibitors. Oncogene (2013) 1.09
Enhancer activation requires trans-recruitment of a mega transcription factor complex. Cell (2014) 1.06
FoxA1 is a key mediator of hormonal response in breast and prostate cancer. Front Endocrinol (Lausanne) (2012) 1.02
Molecular architecture of transcription factor hotspots in early adipogenesis. Cell Rep (2014) 0.98
Genome-wide activity of unliganded estrogen receptor-α in breast cancer cells. Proc Natl Acad Sci U S A (2014) 0.95
Steroid Receptors Reprogram FoxA1 Occupancy through Dynamic Chromatin Transitions. Cell (2016) 0.94
TNFα signaling exposes latent estrogen receptor binding sites to alter the breast cancer cell transcriptome. Mol Cell (2015) 0.94
Transient estrogen receptor binding and p300 redistribution support a squelching mechanism for estradiol-repressed genes. Mol Endocrinol (2014) 0.92
Gene-specific transcription activation via long-range allosteric shape-shifting. Biochem J (2011) 0.91
RUNX1, an androgen- and EZH2-regulated gene, has differential roles in AR-dependent and -independent prostate cancer. Oncotarget (2015) 0.89
1,25-Dihydroxyvitamin D3 Controls a Cohort of Vitamin D Receptor Target Genes in the Proximal Intestine That Is Enriched for Calcium-regulating Components. J Biol Chem (2015) 0.86
Disruption of BRD4 at H3K27Ac-enriched enhancer region correlates with decreased c-Myc expression in Merkel cell carcinoma. Epigenetics (2015) 0.83
The histone variant H2A.Z is an important regulator of enhancer activity. Nucleic Acids Res (2015) 0.81
New therapeutic approaches in breast cancer. Maturitas (2010) 0.80