Published in Proc Natl Acad Sci U S A on November 01, 1978
Energetics of subunit assembly and ligand binding in human hemoglobin. Biophys J (1980) 0.99
Kinetic studies on the oxidation of oxyhemoglobin by biologically active iron thiosemicarbazone complexes: relevance to iron-chelator-induced methemoglobinemia. J Biol Inorg Chem (2013) 0.77
Modification of human haemoglobin with glucose 6-phosphate enhances tetramer-dimer subunit dissociation. Biochem J (1986) 0.75
The Staphylococcus aureus Protein IsdH Inhibits Host Hemoglobin Scavenging to Promote Heme Acquisition by the Pathogen. J Biol Chem (2016) 0.75
LINKED FUNCTIONS AND RECIPROCAL EFFECTS IN HEMOGLOBIN: A SECOND LOOK. Adv Protein Chem (1964) 8.13
Oxygenation-linked subunit interactions in human hemoglobin: analysis of linkage functions for constituent energy terms. Biochemistry (1976) 1.94
Kinetics of deoxyhemoglobin subunit dissociation determined by haptoglobin binding: estimation of the equilibrium constant from forward and reverse rates. Biochemistry (1976) 1.62
Oxygenation-linked subunit interactions in human hemoglobin: experimental studies on the concentration dependence of oxygenation curves. Biochemistry (1976) 1.59
The linkage between oxygenation and subunit dissociation in human hemoglobin. Proc Natl Acad Sci U S A (1974) 1.51
Thermodynamic studies on subunit assembly in human hemoglobin. Temperature dependence of the dimer-tetramer association constants for oxygenated and unliganded hemoglobins. J Biol Chem (1977) 1.47
A convenient chromatographic method for the preparation of human hemoglobin. Anal Biochem (1973) 1.29
Thermodynamic studies on subunit assembly in human hemoglobin. Self-association of oxygenated chains (alphaSH and betaSH): determination of stoichiometries and equilibrium constants as a function of temperature. J Biol Chem (1977) 1.27
Dissociation of hemoglobin into subunits. Ligand-linked dissociation at neutral pH. J Mol Biol (1971) 1.26
The linkage between oxygenation and subunit dissociation in human hemoglobin. Consequences for the analysis of oxygenation curves. Biochemistry (1975) 1.25
Observation of the dissociation of unliganded hemoglobin. J Biol Chem (1972) 1.21
Self-association of hemoglobin betaSH chains is linked to oxygenation. Proc Natl Acad Sci U S A (1978) 0.99
Relation between allosteric effects and changes in the energy of bonding between molecular subunits. J Mol Biol (1969) 0.96
Resolvability of Adair constants from oxygenation curves measured at low hemoglobin concentration. Biophys Chem (1977) 0.91
Molecular sieve studies of interacting protein systems. V. Association of subunits of D-amino acid oxidase apoenzyme. Biochemistry (1969) 0.90
STOICHIOMETRY OF HEMOGLOBIN REACTIONS. Science (1963) 0.89
Equilibrium gel permeation: a single-photon counting spectrophotometer for studies of protein interaction. Biophys Chem (1976) 0.85
Hemoglobin Hirose, a human hemoglobin variant with a substitution at the alpha1beta2 interface. Subunit dissociation and the equilibria and kinetics of ligand binding. J Biol Chem (1978) 0.83
The OR control system of bacteriophage lambda. A physical-chemical model for gene regulation. J Mol Biol (1985) 5.79
Analysis of data from the analytical ultracentrifuge by nonlinear least-squares techniques. Biophys J (1981) 5.57
Quantitative model for gene regulation by lambda phage repressor. Proc Natl Acad Sci U S A (1982) 4.93
Consideration of the Possibility that the slow step in protein denaturation reactions is due to cis-trans isomerism of proline residues. Biochemistry (1975) 4.65
lambda Repressor and cro--components of an efficient molecular switch. Nature (1981) 4.52
Quantitative DNase footprint titration: a method for studying protein-DNA interactions. Methods Enzymol (1986) 3.36
National Academy of Clinical Biochemistry Standards of Laboratory Practice: recommendations for the use of cardiac markers in coronary artery diseases. Clin Chem (1999) 2.90
Two step mechanism of phosphate release and the mechanism of force generation in chemically skinned fibers of rabbit psoas muscle. Biophys J (1991) 2.54
Analytical gel chromatography of proteins. Adv Protein Chem (1970) 2.42
"Footprint" titrations yield valid thermodynamic isotherms. Proc Natl Acad Sci U S A (1986) 2.35
Oxygenation-linked subunit interactions in human hemoglobin: analysis of linkage functions for constituent energy terms. Biochemistry (1976) 1.94
Cardiac troponin-T immunoassay for diagnosis of acute myocardial infarction. Clin Chem (1994) 1.90
Quantitative characterization of the thrombin-heparin interaction. Discrimination between specific and nonspecific binding models. J Biol Chem (1991) 1.72
Energetics of cooperative protein-DNA interactions: comparison between quantitative deoxyribonuclease footprint titration and filter binding. Biochemistry (1986) 1.69
Role of MgATP and MgADP in the cross-bridge kinetics in chemically skinned rabbit psoas fibers. Study of a fast exponential process (C) Biophys J (1989) 1.63
Kinetics of deoxyhemoglobin subunit dissociation determined by haptoglobin binding: estimation of the equilibrium constant from forward and reverse rates. Biochemistry (1976) 1.62
Molecular sieve studies of interacting protein systems. I. Equations for transport of associating systems. J Biol Chem (1967) 1.62
Hydrogen exchange measurement of the free energy of structural and allosteric change in hemoglobin. Science (1992) 1.60
Oxygenation-linked subunit interactions in human hemoglobin: experimental studies on the concentration dependence of oxygenation curves. Biochemistry (1976) 1.59
Free energy coupling within macromolecules. The chemical work of ligand binding at the individual sites in co-operative systems. J Mol Biol (1983) 1.55
An endogenous digoxin-like substance in patients with renal impairment. Ann Intern Med (1983) 1.53
The linkage between oxygenation and subunit dissociation in human hemoglobin. Proc Natl Acad Sci U S A (1974) 1.51
Endogenous digoxin-like immunoreactive factors: impact on digoxin measurements and potential physiological implications. Clin Chem (1985) 1.49
Coupled energetics of lambda cro repressor self-assembly and site-specific DNA operator binding II: cooperative interactions of cro dimers. J Mol Biol (2000) 1.47
Thermodynamic studies on subunit assembly in human hemoglobin. Temperature dependence of the dimer-tetramer association constants for oxygenated and unliganded hemoglobins. J Biol Chem (1977) 1.47
Self-assembly of bacteriophage lambda cI repressor: effects of single-site mutations on the monomer-dimer equilibrium. Biochemistry (1994) 1.43
Digoxin immunoassay with cross-reactivity of digoxin metabolites proportional to their biological activity. Clin Chem (1994) 1.43
Effects of site-specific amino acid modification on protein interactions and biological function. Annu Rev Biochem (1985) 1.42
Long-range, small magnitude nonadditivity of mutational effects in proteins. Biochemistry (1995) 1.41
Prolongation of canine pancreas allograft survival with cyclosporin A: preliminary report. Br Med J (1980) 1.38
Experimental resolution of cooperative free energies for the ten ligation states of human hemoglobin. Proc Natl Acad Sci U S A (1985) 1.34
Energetics of subunit dimerization in bacteriophage lambda cI repressor: linkage to protons, temperature, and KCl. Biochemistry (1991) 1.31
Probing the energetics of proteins through structural perturbation: sites of regulatory energy in human hemoglobin. Proc Natl Acad Sci U S A (1982) 1.28
Thermodynamic studies on subunit assembly in human hemoglobin. Self-association of oxygenated chains (alphaSH and betaSH): determination of stoichiometries and equilibrium constants as a function of temperature. J Biol Chem (1977) 1.27
Mutual effects of protons, NaCl, and oxygen on the dimer-tetramer assembly of human hemoglobin. The dimer Bohr effect. J Biol Chem (1981) 1.27
Site-specific enthalpic regulation of DNA transcription at bacteriophage lambda OR. Biochemistry (1992) 1.27
The linkage between oxygenation and subunit dissociation in human hemoglobin. Consequences for the analysis of oxygenation curves. Biochemistry (1975) 1.25
Mutagenic dissection of hemoglobin cooperativity: effects of amino acid alteration on subunit assembly of oxy and deoxy tetramers. Proteins (1992) 1.22
Measurement and analysis of ligand-linked subunit dissociation equilibria in human hemoglobins. Methods Enzymol (1981) 1.21
Isolation of lambda repressor mutants with defects in cooperative operator binding. Biochemistry (1993) 1.17
Linked functions in allosteric proteins. Extension of the concerted (MWC) model for ligand-linked subunit assembly and its application to human hemoglobins. J Mol Biol (1981) 1.17
Coupled energetics of lambda cro repressor self-assembly and site-specific DNA operator binding I: analysis of cro dimerization from nanomolar to micromolar concentrations. Biochemistry (2000) 1.17
Single-site mutations in the C-terminal domain of bacteriophage lambda cI repressor alter cooperative interactions between dimers adjacently bound to OR. Biochemistry (1994) 1.16
Determination of the equilibrium constants of associating protein systems. 3. Evaluation of the weight fraction of monomer from the weight-average partition coefficient (application to bovine liver glutamate dehydrogenase). Biochemistry (1969) 1.15
Calorimetric analysis of lambda cI repressor binding to DNA operator sites. Biochemistry (1995) 1.15
Understanding the sodium pump and its relevance to disease. Clin Chem (1994) 1.13
Pharmacogenetics: a laboratory tool for optimizing therapeutic efficiency. Clin Chem (1997) 1.11
Endogenous substance in newborn infants causing false positive digoxin measurements. J Pediatr (1983) 1.09
Measurement of DNA-protein equilibria using gel chromatography: application to the HinfI restriction endonuclease. Biochemistry (1985) 1.07
Infantile hypophosphatasia: enzyme replacement therapy by intravenous infusion of alkaline phosphatase-rich plasma from patients with Paget bone disease. J Pediatr (1982) 1.07
Cooperativity mutants of bacteriophage lambda cI repressor: temperature dependence of self-assembly. Biochemistry (1996) 1.05
Thermodynamic analysis of human hemoglobins in terms of the Perutz mechanism: extensions of the Szabo--Karplus model to include subunit assembly. Biochemistry (1982) 1.03
Study of protein subunit association equilibria by elution gel chromatography. Methods Enzymol (1979) 1.03
Studies of protein ligand binding by gel permeation techniques. Methods Enzymol (1973) 1.00
Self-association of hemoglobin betaSH chains is linked to oxygenation. Proc Natl Acad Sci U S A (1978) 0.99
Quantitative study of protein association at picomolar concentrations: the lambda phage cl repressor. Anal Biochem (1991) 0.99
Energetics of subunit assembly and ligand binding in human hemoglobin. Biophys J (1980) 0.99
Hydropathic analysis of the non-covalent interactions between molecular subunits of structurally characterized hemoglobins. J Mol Biol (1997) 0.98
A quantitative model for the cooperative mechanism of human hemoglobin. Proc Natl Acad Sci U S A (1984) 0.97
Progesterone receptor in granulosa cell tumor. Gynecol Oncol (1982) 0.97
The hemoglobin tetramer: a three-state molecular switch for control of ligand affinity. Annu Rev Biophys Biophys Chem (1987) 0.97
Calorimetric determination of the heat of oxygenation of human hemolgobin as a function of pH and the extent of reaction. Biochemistry (1974) 0.96
Differential scanning calorimetry of asparate transcarbamoylase and its isolate subunits. J Biol Chem (1978) 0.96
Protein binding of endogenous digoxin-immunoactive factors in human serum and its variation with clinical condition. J Clin Endocrinol Metab (1985) 0.94
Subunit association of enzyme I of the Salmonella typhimurium phosphoenolpyruvate: glycose phosphotransferase system. Temperature dependence and thermodynamic properties. J Biol Chem (1984) 0.94
Thermodynamic studies on the oxygenation and subunit association of human hemoglobin. Temperature dependence of the linkage between dimer-tetramer association and oxygenation state. J Biol Chem (1979) 0.94
Energetics of oxygenation-linked subunit interactions in human hemoglobin. Biochem Biophys Res Commun (1976) 0.92
Subunit hybridization studies of partially ligated cyanomethemoglobins using a cryogenic method. Evidence for three allosteric states. Biophys Chem (1990) 0.92
Approaches to minimizing interference by cross-reacting molecules in immunoassays. Clin Chem (1991) 0.92
Quaternary enhancement in binding of oxygen by human hemoglobin. Proc Natl Acad Sci U S A (1979) 0.91
Resolvability of Adair constants from oxygenation curves measured at low hemoglobin concentration. Biophys Chem (1977) 0.91
pH-dependent conformational states of horse liver alcohol dehydrogenase. J Biol Chem (1977) 0.90
Proton-linked contributions to site-specific interactions of lambda cI repressor and OR. Biochemistry (1990) 0.90
Molecular sieve studies of interacting protein systems. V. Association of subunits of D-amino acid oxidase apoenzyme. Biochemistry (1969) 0.90
Electrostatic contributions to the energetics of dimer-tetramer assembly in human hemoglobin: pH dependence and effect of specifically bound chloride ions. Biochemistry (1981) 0.90
Antiinflammatory activity of a Ghanaian antiarthritic herbal preparation: III. J Ethnopharmacol (1995) 0.90
Thermodynamic studies on ligand binding and subunit association of human hemoglobins. Enthalpies of binding O2 and CO to subunit chains of hemoglobin A. J Biol Chem (1979) 0.89
Endogenous digoxin-immunoreactive substance in human pregnancies. J Clin Endocrinol Metab (1984) 0.88
Comparative study of the ability of four aminoglycoside assay techniques to detect the inactivation of aminoglycosides by beta-lactam antibiotics. Diagn Microbiol Infect Dis (1984) 0.88
Topological measurement of protein-induced DNA bend angles. J Mol Biol (1996) 0.88
Thermodynamic studies on subunit assembly in human hemoglobin. Calorimetric measurements on the reconstitution of oxyhemoglobin from isolated chains. J Biol Chem (1977) 0.88
Functional properties of human hemoglobins synthesized from recombinant mutant beta-globins. Biochemistry (1992) 0.88
The pathway of allosteric control as revealed by hemoglobin intermediate states. FASEB J (1995) 0.88
Regulation of oxygen affinity by quaternary enhancement: does hemoglobin Ypsilanti represent an allosteric intermediate? Proteins (1992) 0.87
Aspartokinase I-homoserine dehydrogenase I of Escherichia coli K12. Concentration-dependent dissociation to dimers in the presence of L-threonine. J Biol Chem (1978) 0.87
Single-site modifications of half-ligated hemoglobin reveal autonomous dimer cooperativity within a quaternary T tetramer. Proteins (1993) 0.87
Isolation of digoxin-like immunoreactive factors from mammalian adrenal cortex. J Biol Chem (1991) 0.86
Molecular sieve studies of interacting protein systems. IV. Molecular size of the D-amino acid oxidase apoenzyme subunit. J Biol Chem (1969) 0.86
Simultaneous rapid measurement of whole blood myoglobin, creatine kinase MB, and cardiac troponin I by the triage cardiac panel for detection of myocardial infarction. Clin Chem (1999) 0.86
Estrogen and progesterone receptor assays on breast carcinoma from mastectomy specimens. Cancer (1983) 0.86
Molecular sieve studies of interacting protein systems. X. Behavior of small zone profiles for reversibly self-associating solutes. J Biol Chem (1971) 0.86
Direct and indirect pathways of functional coupling in human hemoglobin are revealed by quantitative low-temperature isoelectric focusing of mutant hybrids. Biochemistry (1990) 0.86