Published in Biochemistry on November 30, 1976
Evaluation and propagation of confidence intervals in nonlinear, asymmetrical variance spaces. Analysis of ligand-binding data. Biophys J (1983) 1.36
Probing the energetics of proteins through structural perturbation: sites of regulatory energy in human hemoglobin. Proc Natl Acad Sci U S A (1982) 1.28
Structure-specific model of hemoglobin cooperativity. Proc Natl Acad Sci U S A (1983) 1.16
Self-association of hemoglobin betaSH chains is linked to oxygenation. Proc Natl Acad Sci U S A (1978) 0.99
Energetics of subunit assembly and ligand binding in human hemoglobin. Biophys J (1980) 0.99
Ligand-promoted weakening of intersubunit bonding domains in aspartate transcarbamolylase. Proc Natl Acad Sci U S A (1977) 0.98
A quantitative model for the cooperative mechanism of human hemoglobin. Proc Natl Acad Sci U S A (1984) 0.97
Gene duplication and the evolution of hemoglobin isoform differentiation in birds. J Biol Chem (2012) 0.96
Quaternary enhancement in binding of oxygen by human hemoglobin. Proc Natl Acad Sci U S A (1979) 0.91
Order of free energy couplings between ligand binding and protein subunit association in hemoglobin. Proc Natl Acad Sci U S A (1984) 0.85
Three-state combinatorial switching in hemoglobin tetramers: comparison between functional energetics and molecular structures. Proc Natl Acad Sci U S A (1987) 0.85
The oxygen-binding intermediates of human hemoglobin: evaluation of their contributions to cooperativity using zinc-containing hybrids. Biophys J (1996) 0.83
Reciprocal effects in human hemoglobin: direct measurement of the dimer-tetramer association constant at partial oxygen saturation. Proc Natl Acad Sci U S A (1978) 0.80
Allosteric interpretation of the measurement of cooperative free energy in cyanomethemoglobin. Proc Natl Acad Sci U S A (1986) 0.80
Allosteric kinetics and equilibria of triligated, cross-linked hemoglobin. Biophys J (1993) 0.80
Single residue modification of only one dimer within the hemoglobin tetramer reveals autonomous dimer function. Proc Natl Acad Sci U S A (2002) 0.80
Heterotropic effectors exert more significant strain on monoligated than on unligated hemoglobin. Biophys J (1999) 0.80
Nanosecond time-resolved absorption studies of human oxyhemoglobin photolysis intermediates. Biophys J (1996) 0.79
Changes in the apparent quantum efficiency for photolysis of Hb(CO)1. Biophys J (1989) 0.79
Role of dimerization in the control of the functioning of the human haemoglobin mutant haemoglobin Howick (beta 37 Trp-->Gly). Biochem J (1994) 0.78
Characterization of diadzein-hemoglobin binding using optical spectroscopy and molecular dynamics simulations. Int J Biol Macromol (2012) 0.78
Linkage between ligand binding and the dimer-tetramer equilibrium in the Monod-Wyman-Changeux model of hemoglobin. Proc Natl Acad Sci U S A (1986) 0.77
Recruitment of rare 3-grams at functional sites: is this a mechanism for increasing enzyme specificity? BMC Bioinformatics (2007) 0.76
Resolvability of free energy changes for oxygen binding and subunit association by human hemoglobin. Biophys J (1989) 0.75
Hemoglobin Evanston (alpha 14 Trp----Arg). An unstable alpha-chain variant expressed as alpha-thalassemia. J Clin Invest (1984) 0.75
The OR control system of bacteriophage lambda. A physical-chemical model for gene regulation. J Mol Biol (1985) 5.79
Analysis of data from the analytical ultracentrifuge by nonlinear least-squares techniques. Biophys J (1981) 5.57
Surgical management of brain metastases: how aggressive should we be? Oncology (Williston Park) (1989) 4.95
Quantitative model for gene regulation by lambda phage repressor. Proc Natl Acad Sci U S A (1982) 4.93
lambda Repressor and cro--components of an efficient molecular switch. Nature (1981) 4.52
Quantitative histology of Wallerian degeneration: I. Nuclear population in rabbit sciatic nerve. J Anat (1946) 4.48
Antimicrobial therapy of experimental endocarditis caused by Staphylococcus aureus. J Infect Dis (1975) 3.52
Quantitative DNase footprint titration: a method for studying protein-DNA interactions. Methods Enzymol (1986) 3.36
Cluster analysis: a simple, versatile, and robust algorithm for endocrine pulse detection. Am J Physiol (1986) 2.94
The association between the quality of inpatient care and early readmission. Ann Intern Med (1995) 2.86
Clearance of HSV-2 from recurrent genital lesions correlates with infiltration of HSV-specific cytotoxic T lymphocytes. J Clin Invest (1998) 2.85
Analytical gel chromatography of proteins. Adv Protein Chem (1970) 2.42
Fluorescence lifetime imaging of free and protein-bound NADH. Proc Natl Acad Sci U S A (1992) 2.42
A critical evaluation of real-time ultrasonography for the study of gallbladder volume and contraction. Gastroenterology (1980) 2.39
"Footprint" titrations yield valid thermodynamic isotherms. Proc Natl Acad Sci U S A (1986) 2.35
Saltation and stasis: a model of human growth. Science (1992) 2.28
Primary Carcinoma of the Gallbladder : An Additional Reason for Early Removal of the Calculous Gallbladder. Ann Surg (1945) 2.23
Within germinal centers, isotype switching of immunoglobulin genes occurs after the onset of somatic mutation. Immunity (1996) 2.22
The pituitary gland secretes in bursts: appraising the nature of glandular secretory impulses by simultaneous multiple-parameter deconvolution of plasma hormone concentrations. Proc Natl Acad Sci U S A (1987) 2.02
Effects of pregnancy and contraceptive steroids on gallbladder function. N Engl J Med (1980) 1.98
Oxygenation-linked subunit interactions in human hemoglobin: analysis of linkage functions for constituent energy terms. Biochemistry (1976) 1.94
DNase I hypersensitive sites in the chromatin of human mu immunoglobulin heavy-chain genes. Nature (1984) 1.94
Activated mast cells produce interleukin 13. J Exp Med (1995) 1.86
Skin lesions in ulcerative colitis. Gut (1969) 1.78
Attenuation of luteinizing hormone secretory burst amplitude as a proximate basis for the hypoandrogenism of healthy aging in men. J Clin Endocrinol Metab (1992) 1.76
Diverse and contrasting effects of habitat fragmentation. Science (1992) 1.76
A reassessment of the echocardiogram in mitral stenosis. Circulation (1975) 1.74
Energetics of cooperative protein-DNA interactions: comparison between quantitative deoxyribonuclease footprint titration and filter binding. Biochemistry (1986) 1.69
Alcohol metabolism in Asian-American men with genetic polymorphisms of aldehyde dehydrogenase. Ann Intern Med (1997) 1.63
Kinetics of deoxyhemoglobin subunit dissociation determined by haptoglobin binding: estimation of the equilibrium constant from forward and reverse rates. Biochemistry (1976) 1.62
Molecular sieve studies of interacting protein systems. I. Equations for transport of associating systems. J Biol Chem (1967) 1.62
Hydrogen exchange measurement of the free energy of structural and allosteric change in hemoglobin. Science (1992) 1.60
Free energy coupling within macromolecules. The chemical work of ligand binding at the individual sites in co-operative systems. J Mol Biol (1983) 1.55
The linkage between oxygenation and subunit dissociation in human hemoglobin. Proc Natl Acad Sci U S A (1974) 1.51
Non-academic factors in medical school selection: a report on rejected applicants. Br J Med Educ (1971) 1.51
On teaching dermatology to nondermatologists. Arch Dermatol (1994) 1.48
An empirical assessment of the validity of explicit and implicit process-of-care criteria for quality assessment. Med Care (1999) 1.48
Coupled energetics of lambda cro repressor self-assembly and site-specific DNA operator binding II: cooperative interactions of cro dimers. J Mol Biol (2000) 1.47
Bone biomechanical properties in LRP5 mutant mice. Bone (2004) 1.47
Thermodynamic studies on subunit assembly in human hemoglobin. Temperature dependence of the dimer-tetramer association constants for oxygenated and unliganded hemoglobins. J Biol Chem (1977) 1.47
International Classification of Diseases, 9th Revision, Clinical Modification codes in discharge abstracts are poor measures of complication occurrence in medical inpatients. Med Care (1997) 1.47
Kinetics of serum interferon response in mice after single and multiple injections of polyI-poly C. Proc Soc Exp Biol Med (1971) 1.47
Self-assembly of bacteriophage lambda cI repressor: effects of single-site mutations on the monomer-dimer equilibrium. Biochemistry (1994) 1.43
Experimental endocarditis. IV. Tricuspid and aortic valve infection with Candida albicans in rabbits. Yale J Biol Med (1972) 1.42
Analysis of residuals: criteria for determining goodness-of-fit. Methods Enzymol (1992) 1.42
Enhanced basal and disorderly growth hormone secretion distinguish acromegalic from normal pulsatile growth hormone release. J Clin Invest (1994) 1.42
Effects of site-specific amino acid modification on protein interactions and biological function. Annu Rev Biochem (1985) 1.42
Long-range, small magnitude nonadditivity of mutational effects in proteins. Biochemistry (1995) 1.41
Dual defects in pulsatile growth hormone secretion and clearance subserve the hyposomatotropism of obesity in man. J Clin Endocrinol Metab (1991) 1.40
Self-perception of need amongst the elderly: an analysis of illness. Sociol Rev (1972) 1.40
Premedical Zoology. Br Med J (1945) 1.39
Percutaneous nephrostomy: a series and review of the literature. AJR Am J Roentgenol (1978) 1.38
Wrinkles induced by the use of smoothing procedures applied to serial growth data. Ann Hum Biol (1998) 1.38
Excisional treatment of cavernous hemangioma of the liver. Ann Surg (1980) 1.37
Evaluation and propagation of confidence intervals in nonlinear, asymmetrical variance spaces. Analysis of ligand-binding data. Biophys J (1983) 1.36
Fasting enhances growth hormone secretion and amplifies the complex rhythms of growth hormone secretion in man. J Clin Invest (1988) 1.36
Monte Carlo method for determining complete confidence probability distributions of estimated model parameters. Methods Enzymol (1992) 1.36
Experimental resolution of cooperative free energies for the ten ligation states of human hemoglobin. Proc Natl Acad Sci U S A (1985) 1.34
Contemporary aspects of discrete peak-detection algorithms. I. The paradigm of the luteinizing hormone pulse signal in men. Endocr Rev (1988) 1.33
B-mode echoencephalography in the normal and high risk infant. AJR Am J Roentgenol (1979) 1.33
A method of developing and weighting explicit process of care criteria for quality assessment. Med Care (1994) 1.33
Interleukin-10 induces immunoglobulin G isotype switch recombination in human CD40-activated naive B lymphocytes. J Exp Med (1996) 1.32
Secretory process regularity monitors neuroendocrine feedback and feedforward signaling strength in humans. Am J Physiol Regul Integr Comp Physiol (2001) 1.32
Animal models of placental angiogenesis. Placenta (2005) 1.31
Energetics of subunit dimerization in bacteriophage lambda cI repressor: linkage to protons, temperature, and KCl. Biochemistry (1991) 1.31
Probing the energetics of proteins through structural perturbation: sites of regulatory energy in human hemoglobin. Proc Natl Acad Sci U S A (1982) 1.28
The roles of iNOS in liver ischemia-reperfusion injury. Shock (2001) 1.28
Thermodynamic studies on subunit assembly in human hemoglobin. Self-association of oxygenated chains (alphaSH and betaSH): determination of stoichiometries and equilibrium constants as a function of temperature. J Biol Chem (1977) 1.27
Biologically active luteinizing hormone is secreted in episodic pulsations that vary in relation to stage of the menstrual cycle. J Clin Endocrinol Metab (1984) 1.27
Site-specific enthalpic regulation of DNA transcription at bacteriophage lambda OR. Biochemistry (1992) 1.27
Mutual effects of protons, NaCl, and oxygen on the dimer-tetramer assembly of human hemoglobin. The dimer Bohr effect. J Biol Chem (1981) 1.27
Molecular properties of the reassembled coat protein of coated vesicles. Biochemistry (1980) 1.25
The linkage between oxygenation and subunit dissociation in human hemoglobin. Consequences for the analysis of oxygenation curves. Biochemistry (1975) 1.25
Measurement of mRNA concentration and mRNA half-life as a function of hormonal treatment. Methods Enzymol (1985) 1.25
Amplitude modulation of a burstlike mode of cortisol secretion subserves the circadian glucocorticoid rhythm. Am J Physiol (1989) 1.24
Augmentation of growth hormone secretion during puberty: evidence for a pulse amplitude-modulated phenomenon. J Clin Endocrinol Metab (1987) 1.23
Relationship between dose size and dose interval of polyinosinic polycytidylic acid and interferon hyporesponsiveness in mice. Proc Soc Exp Biol Med (1970) 1.22
Mutagenic dissection of hemoglobin cooperativity: effects of amino acid alteration on subunit assembly of oxy and deoxy tetramers. Proteins (1992) 1.22
Analysis of relaxation kinetics data by a nonlinear least squares method. Biophys Chem (1974) 1.22
Measurement and analysis of ligand-linked subunit dissociation equilibria in human hemoglobins. Methods Enzymol (1981) 1.21
Differential impact of age, sex steroid hormones, and obesity on basal versus pulsatile growth hormone secretion in men as assessed in an ultrasensitive chemiluminescence assay. J Clin Endocrinol Metab (1995) 1.21
Paramyxovirus fusion (F) protein and hemagglutinin-neuraminidase (HN) protein interactions: intracellular retention of F and HN does not affect transport of the homotypic HN or F protein. Virology (1997) 1.21
Some properties of the lactic dehydrogenase agent of mice. J Exp Med (1965) 1.21
Deconvolution analysis of hormone data. Methods Enzymol (1992) 1.20
Binding and internalization of rat colonic mucins by the galactose/N-acetyl-D-galactosamine adherence lectin of Entamoeba histolytica. J Infect Dis (1988) 1.19
Frequency domain imaging of absorbers obscured by scattering. J Photochem Photobiol B (1992) 1.19
A surgical approach to the treatment of fetal hydrocephalus. N Engl J Med (1982) 1.18
Organization of ganglioside GM1 in phosphatidylcholine bilayers. Biochim Biophys Acta (1985) 1.18
Prevalence, morbidity, and cost of dermatologic diseases. J Am Acad Dermatol (1984) 1.18
Impact of pulsatility on the ensemble orderliness (approximate entropy) of neurohormone secretion. Am J Physiol Regul Integr Comp Physiol (2001) 1.17
Isolation of lambda repressor mutants with defects in cooperative operator binding. Biochemistry (1993) 1.17
Coupled energetics of lambda cro repressor self-assembly and site-specific DNA operator binding I: analysis of cro dimerization from nanomolar to micromolar concentrations. Biochemistry (2000) 1.17
Linked functions in allosteric proteins. Extension of the concerted (MWC) model for ligand-linked subunit assembly and its application to human hemoglobins. J Mol Biol (1981) 1.17
Somatic mutation and CDR3 lengths of immunoglobulin kappa light chains expressed in patients with rheumatoid arthritis and in normal individuals. J Clin Invest (1995) 1.16
Single-site mutations in the C-terminal domain of bacteriophage lambda cI repressor alter cooperative interactions between dimers adjacently bound to OR. Biochemistry (1994) 1.16