Published in PLoS Genet on February 16, 2017
The genetics of Caenorhabditis elegans. Genetics (1974) 102.14
Fiji: an open-source platform for biological-image analysis. Nat Methods (2012) 56.92
The DNA-damage response in human biology and disease. Nature (2009) 17.86
The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway. Annu Rev Biochem (2010) 9.80
Structure of chromatin. Annu Rev Biochem (1977) 8.91
Double-strand break end resection and repair pathway choice. Annu Rev Genet (2011) 7.31
Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases. Cell (2006) 7.08
Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications. Genes Dev (2011) 5.60
Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease. Genes Dev (2008) 5.25
The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3. Nature (2006) 4.74
H2A.Z-containing nucleosomes mediate the thermosensory response in Arabidopsis. Cell (2010) 4.54
Regulation of homologous recombination in eukaryotes. Annu Rev Genet (2010) 4.33
Crosstalk between histone modifications during the DNA damage response. Trends Cell Biol (2009) 4.31
A conserved checkpoint pathway mediates DNA damage--induced apoptosis and cell cycle arrest in C. elegans. Mol Cell (2000) 4.11
RTEL1 maintains genomic stability by suppressing homologous recombination. Cell (2008) 3.84
Synaptonemal complex assembly in C. elegans is dispensable for loading strand-exchange proteins but critical for proper completion of recombination. Dev Cell (2003) 3.53
The histone mark H3K36me3 regulates human DNA mismatch repair through its interaction with MutSα. Cell (2013) 2.87
Identification of genes that protect the C. elegans genome against mutations by genome-wide RNAi. Genes Dev (2003) 2.76
GLD-1, a cytoplasmic protein essential for oocyte differentiation, shows stage- and sex-specific expression during Caenorhabditis elegans germline development. Dev Biol (1996) 2.55
Genetic and cytological characterization of the recombination protein RAD-51 in Caenorhabditis elegans. Chromosoma (2003) 2.29
Caenorhabditis elegans msh-5 is required for both normal and radiation-induced meiotic crossing over but not for completion of meiosis. Genetics (2000) 2.22
The Effect of Temperature and Parental Age on Recombination and Nondisjunction in CAENORHABDITIS ELEGANS. Genetics (1979) 2.19
Chromatin remodeling at DNA double-strand breaks. Cell (2013) 2.18
A nuclear Argonaute promotes multigenerational epigenetic inheritance and germline immortality. Nature (2012) 2.04
Prime, repair, restore: the active role of chromatin in the DNA damage response. Mol Cell (2012) 2.04
Methylation of histone H3 lysine 36 enhances DNA repair by nonhomologous end-joining. Proc Natl Acad Sci U S A (2010) 1.94
Overlapping mechanisms promote postsynaptic RAD-51 filament disassembly during meiotic double-strand break repair. Mol Cell (2010) 1.90
Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks. Nat Struct Mol Biol (2014) 1.89
Tumor suppressor gene identification using retroviral insertional mutagenesis in Blm-deficient mice. EMBO J (2006) 1.88
Repair Pathway Choices and Consequences at the Double-Strand Break. Trends Cell Biol (2015) 1.84
MES-4: an autosome-associated histone methyltransferase that participates in silencing the X chromosomes in the C. elegans germ line. Development (2006) 1.63
SETD2-dependent histone H3K36 trimethylation is required for homologous recombination repair and genome stability. Cell Rep (2014) 1.57
Conserved antagonism between JMJD2A/KDM4A and HP1γ during cell cycle progression. Mol Cell (2010) 1.55
Crosstalk between chromatin state and DNA damage response in cellular senescence and cancer. Nat Rev Cancer (2012) 1.45
Rapid and precise engineering of the Caenorhabditis elegans genome with lethal mutation co-conversion and inactivation of NHEJ repair. Genetics (2014) 1.38
On the relationship between heterochromatization and variegation in Drosophila, with special reference to temperature-sensitive periods. Genet Res (1967) 1.36
Identification of conserved pathways of DNA-damage response and radiation protection by genome-wide RNAi. Curr Biol (2006) 1.35
JMJD5 regulates PKM2 nuclear translocation and reprograms HIF-1α-mediated glucose metabolism. Proc Natl Acad Sci U S A (2013) 1.34
Developmental modulation of nonhomologous end joining in Caenorhabditis elegans. Genetics (2006) 1.33
Caenorhabditis elegans POLQ-1 and HEL-308 function in two distinct DNA interstrand cross-link repair pathways. DNA Repair (Amst) (2008) 1.33
SETD2 is required for DNA double-strand break repair and activation of the p53-mediated checkpoint. Elife (2014) 1.33
KDM8, a H3K36me2 histone demethylase that acts in the cyclin A1 coding region to regulate cancer cell proliferation. Proc Natl Acad Sci U S A (2010) 1.31
Replication blocking lesions present a unique substrate for homologous recombination. EMBO J (2007) 1.29
Phenotypic plasticity in Drosophila pigmentation caused by temperature sensitivity of a chromatin regulator network. PLoS Genet (2007) 1.25
The Caenorhabditis elegans homolog of Gen1/Yen1 resolvases links DNA damage signaling to DNA double-strand break repair. PLoS Genet (2010) 1.21
Homologue pairing, recombination and segregation in Caenorhabditis elegans. Genome Dyn (2009) 1.20
EZH2 protects glioma stem cells from radiation-induced cell death in a MELK/FOXM1-dependent manner. Stem Cell Reports (2015) 1.13
Chromatin and the DNA damage response: the cancer connection. Mol Oncol (2011) 1.12
Nucleotide excision repair and the degradation of RNA pol II by the Caenorhabditis elegans XPA and Rsp5 orthologues, RAD-3 and WWP-1. DNA Repair (Amst) (2007) 1.11
Histone marks: repairing DNA breaks within the context of chromatin. Biochem Soc Trans (2012) 1.10
Meiotic recombination in Caenorhabditis elegans. Chromosome Res (2007) 1.08
Methods for studying the DNA damage response in the Caenorhabdatis elegans germ line. Methods Cell Biol (2012) 1.08
Methods for analyzing checkpoint responses in Caenorhabditis elegans. Methods Mol Biol (2004) 1.05
Jmjd5, an H3K36me2 histone demethylase, modulates embryonic cell proliferation through the regulation of Cdkn1a expression. Development (2012) 1.04
JMJD5, a Jumonji C (JmjC) domain-containing protein, negatively regulates osteoclastogenesis by facilitating NFATc1 protein degradation. J Biol Chem (2012) 0.97
Chromatin modifications and DNA repair: beyond double-strand breaks. Front Genet (2014) 0.96
COM-1 promotes homologous recombination during Caenorhabditis elegans meiosis by antagonizing Ku-mediated non-homologous end joining. PLoS Genet (2013) 0.95
Human-chromatin-related protein interactions identify a demethylase complex required for chromosome segregation. Cell Rep (2014) 0.94
Epigenetic regulation of genomic integrity. Chromosoma (2012) 0.93
Histone demethylase JMJD5 is essential for embryonic development. Biochem Biophys Res Commun (2012) 0.92
Crystal structure and functional analysis of JMJD5 indicate an alternate specificity and function. Mol Cell Biol (2012) 0.90
Nucleotide Excision Repair in Caenorhabditis elegans. Mol Biol Int (2011) 0.87
The SET-2/SET1 histone H3K4 methyltransferase maintains pluripotency in the Caenorhabditis elegans germline. Cell Rep (2014) 0.82
H3K4 demethylase activities repress proliferative and postmitotic aging. Aging Cell (2013) 0.81
Genome integrity is regulated by the Caenorhabditis elegans Rad51D homolog rfs-1. Genetics (2008) 0.81
H3K23me2 is a new heterochromatic mark in Caenorhabditis elegans. Nucleic Acids Res (2015) 0.81
Meiosis. WormBook (2015) 0.81
Identification and functional implication of nuclear localization signals in the N-terminal domain of JMJD5. Biochimie (2013) 0.79
Overexpression of KDM4 lysine demethylases disrupts the integrity of the DNA mismatch repair pathway. Biol Open (2015) 0.79
The atm-1 gene is required for genome stability in Caenorhabditis elegans. Mol Genet Genomics (2012) 0.79
ATM-mediated KDM2A phosphorylation is required for the DNA damage repair. Oncogene (2015) 0.79
Structure of the JmjC-domain-containing protein JMJD5. Acta Crystallogr D Biol Crystallogr (2013) 0.79
JMJD5 (Jumonji Domain-containing 5) Associates with Spindle Microtubules and Is Required for Proper Mitosis. J Biol Chem (2015) 0.77
The H3K4me3/2 histone demethylase RBR-2 controls axon guidance by repressing the actin-remodeling gene wsp-1. Development (2016) 0.76
A role for the malignant brain tumour (MBT) domain protein LIN-61 in DNA double-strand break repair by homologous recombination. PLoS Genet (2013) 0.76
Axon injury triggers EFA-6 mediated destabilization of axonal microtubules via TACC and doublecortin like kinase. Elife (2015) 0.84
A combined binary interaction and phenotypic map of C. elegans cell polarity proteins. Nat Cell Biol (2016) 0.76
A tissue-specific protein purification approach in Caenorhabditis elegans identifies novel interaction partners of DLG-1/Discs large. BMC Biol (2016) 0.75
Multisite Phosphorylation of NuMA-Related LIN-5 Controls Mitotic Spindle Positioning in C. elegans. PLoS Genet (2016) 0.75