Published in Mol Cell on January 29, 2010
Expanded roles of the Fanconi anemia pathway in preserving genomic stability. Genes Dev (2010) 3.33
Inhibition of homologous recombination by the PCNA-interacting protein PARI. Mol Cell (2011) 2.61
Homologous recombination and its regulation. Nucleic Acids Res (2012) 2.44
Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair. Nature (2015) 2.04
Repair Pathway Choices and Consequences at the Double-Strand Break. Trends Cell Biol (2015) 1.84
DNA helicases involved in DNA repair and their roles in cancer. Nat Rev Cancer (2013) 1.58
HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis. Nature (2013) 1.57
RTEL1: an essential helicase for telomere maintenance and the regulation of homologous recombination. Nucleic Acids Res (2010) 1.27
Swi2/Snf2-related translocases prevent accumulation of toxic Rad51 complexes during mitotic growth. Mol Cell (2010) 1.17
Meiosis: making a break for it. Curr Opin Cell Biol (2010) 1.16
TRF2 recruits RTEL1 to telomeres in S phase to promote t-loop unwinding. Mol Cell (2015) 1.03
DNA double-strand break repair in Caenorhabditis elegans. Chromosoma (2010) 1.00
FBH1 helicase disrupts RAD51 filaments in vitro and modulates homologous recombination in mammalian cells. J Biol Chem (2013) 0.94
Rad51 Paralogs Remodel Pre-synaptic Rad51 Filaments to Stimulate Homologous Recombination. Cell (2015) 0.92
Human DNA helicase HELQ participates in DNA interstrand crosslink tolerance with ATR and RAD51 paralogs. Nat Commun (2013) 0.89
PcrA-mediated disruption of RecA nucleoprotein filaments--essential role of the ATPase activity of RecA. Nucleic Acids Res (2012) 0.86
Helq acts in parallel to Fancc to suppress replication-associated genome instability. Nucleic Acids Res (2013) 0.85
Novel function of the Fanconi anemia group J or RECQ1 helicase to disrupt protein-DNA complexes in a replication protein A-stimulated manner. J Biol Chem (2014) 0.85
A failure of meiotic chromosome segregation in a fbh1Delta mutant correlates with persistent Rad51-DNA associations. Nucleic Acids Res (2010) 0.83
Novel insights into RAD51 activity and regulation during homologous recombination and DNA replication. Biochem Cell Biol (2016) 0.82
Meiosis. WormBook (2015) 0.81
Promotion of Homologous Recombination by SWS-1 in Complex with RAD-51 Paralogs in Caenorhabditis elegans. Genetics (2016) 0.79
Synthetic cytotoxicity: digenic interactions with TEL1/ATM mutations reveal sensitivity to low doses of camptothecin. Genetics (2014) 0.78
Eviction notice: new insights into Rad51 removal from DNA during homologous recombination. Mol Cell (2010) 0.78
C. elegans ring finger protein RNF-113 is involved in interstrand DNA crosslink repair and interacts with a RAD51C homolog. PLoS One (2013) 0.77
Meiotic recombination and the crossover assurance checkpoint in Caenorhabditis elegans. Semin Cell Dev Biol (2016) 0.77
Aging impairs double-strand break repair by homologous recombination in Drosophila germ cells. Aging Cell (2016) 0.76
Remodeling and Control of Homologous Recombination by DNA Helicases and Translocases that Target Recombinases and Synapsis. Genes (Basel) (2016) 0.75
REC-1 and HIM-5 distribute meiotic crossovers and function redundantly in meiotic double-strand break formation in Caenorhabditis elegans. Genes Dev (2015) 0.75
Structure-function analysis of DNA helicase HELQ: A new diagnostic marker in ovarian cancer. Oncol Lett (2016) 0.75
JMJD-5/KDM8 regulates H3K36me2 and is required for late steps of homologous recombination and genome integrity. PLoS Genet (2017) 0.75
Assessment of HTLV-1 proviral load, LAT, BIM, c-FOS and RAD51 gene expression in adult T cell leukemia/lymphoma. Med Microbiol Immunol (2017) 0.75
Playing the end game: DNA double-strand break repair pathway choice. Mol Cell (2012) 5.42
RTEL1 maintains genomic stability by suppressing homologous recombination. Cell (2008) 3.84
Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1. Science (2009) 3.68
Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins. Nature (2008) 3.67
Synaptonemal complex assembly in C. elegans is dispensable for loading strand-exchange proteins but critical for proper completion of recombination. Dev Cell (2003) 3.53
A critical role for the ubiquitin-conjugating enzyme Ubc13 in initiating homologous recombination. Mol Cell (2007) 3.23
RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection. Mol Cell (2013) 3.05
Preventing nonhomologous end joining suppresses DNA repair defects of Fanconi anemia. Mol Cell (2010) 2.91
Mutations in the mitochondrial protease gene AFG3L2 cause dominant hereditary ataxia SCA28. Nat Genet (2010) 2.66
Inhibition of homologous recombination by the PCNA-interacting protein PARI. Mol Cell (2011) 2.61
A conserved pathway to activate BRCA1-dependent ubiquitylation at DNA damage sites. EMBO J (2006) 2.41
MMS19 links cytoplasmic iron-sulfur cluster assembly to DNA metabolism. Science (2012) 2.39
The DNA damage checkpoint response requires histone H2B ubiquitination by Rad6-Bre1 and H3 methylation by Dot1. J Biol Chem (2005) 2.27
Regulation of the myosin-directed chaperone UNC-45 by a novel E3/E4-multiubiquitylation complex in C. elegans. Cell (2004) 2.26
RTEL1 dismantles T loops and counteracts telomeric G4-DNA to maintain telomere integrity. Cell (2012) 2.24
FANCM and FAAP24 function in ATR-mediated checkpoint signaling independently of the Fanconi anemia core complex. Mol Cell (2008) 2.14
Caenorhabditis elegans HUS-1 is a DNA damage checkpoint protein required for genome stability and EGL-1-mediated apoptosis. Curr Biol (2002) 2.06
The ubiquitin-selective chaperone CDC-48/p97 links myosin assembly to human myopathy. Nat Cell Biol (2007) 2.04
NEK8 links the ATR-regulated replication stress response and S phase CDK activity to renal ciliopathies. Mol Cell (2013) 1.97
Distinct modes of ATR activation after replication stress and DNA double-strand breaks in Caenorhabditis elegans. EMBO J (2005) 1.94
FANCJ is a structure-specific DNA helicase associated with the maintenance of genomic G/C tracts. J Biol Chem (2008) 1.93
Histone methyltransferase Dot1 and Rad9 inhibit single-stranded DNA accumulation at DSBs and uncapped telomeres. EMBO J (2008) 1.89
A novel actin barbed-end-capping activity in EPS-8 regulates apical morphogenesis in intestinal cells of Caenorhabditis elegans. Nat Cell Biol (2004) 1.82
HCLK2 is essential for the mammalian S-phase checkpoint and impacts on Chk1 stability. Nat Cell Biol (2007) 1.77
HTP-3 links DSB formation with homolog pairing and crossing over during C. elegans meiosis. Dev Cell (2008) 1.76
POLQ (Pol theta), a DNA polymerase and DNA-dependent ATPase in human cells. Nucleic Acids Res (2003) 1.76
RAD-51-dependent and -independent roles of a Caenorhabditis elegans BRCA2-related protein during DNA double-strand break repair. Mol Cell Biol (2005) 1.74
RNase H and postreplication repair protect cells from ribonucleotides incorporated in DNA. Mol Cell (2012) 1.74
RTEL-1 enforces meiotic crossover interference and homeostasis. Science (2010) 1.70
Cdc28-Clb5 (CDK-S) and Cdc7-Dbf4 (DDK) collaborate to initiate meiotic recombination in yeast. Genes Dev (2008) 1.68
Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint. EMBO J (2004) 1.65
DNA nucleotide excision repair-dependent signaling to checkpoint activation. Proc Natl Acad Sci U S A (2006) 1.64
HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis. Nature (2013) 1.57
Loading of meiotic cohesin by SCC-2 is required for early processing of DSBs and for the DNA damage checkpoint. Curr Biol (2011) 1.57
BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair. J Cell Sci (2012) 1.55
Phosphorylation of the budding yeast 9-1-1 complex is required for Dpb11 function in the full activation of the UV-induced DNA damage checkpoint. Mol Cell Biol (2008) 1.54
DOG-1 is the Caenorhabditis elegans BRIP1/FANCJ homologue and functions in interstrand cross-link repair. Mol Cell Biol (2007) 1.53
BRCA1/BARD1 orthologs required for DNA repair in Caenorhabditis elegans. Curr Biol (2004) 1.52
Caenorhabditis elegans HIM-18/SLX-4 interacts with SLX-1 and XPF-1 and maintains genomic integrity in the germline by processing recombination intermediates. PLoS Genet (2009) 1.52
CK2 phospho-dependent binding of R2TP complex to TEL2 is essential for mTOR and SMG1 stability. Mol Cell (2010) 1.51
The choice in meiosis - defining the factors that influence crossover or non-crossover formation. J Cell Sci (2011) 1.49
Inhibitors of the proteasome suppress homologous DNA recombination in mammalian cells. Cancer Res (2007) 1.48
The Caenorhabditis elegans Elongator complex regulates neuronal alpha-tubulin acetylation. PLoS Genet (2010) 1.45
Ribonucleotides misincorporated into DNA act as strand-discrimination signals in eukaryotic mismatch repair. Mol Cell (2013) 1.44
CeBRC-2 stimulates D-loop formation by RAD-51 and promotes DNA single-strand annealing. J Mol Biol (2006) 1.42
Caenorhabditis elegans POLQ-1 and HEL-308 function in two distinct DNA interstrand cross-link repair pathways. DNA Repair (Amst) (2008) 1.33
Exo1 competes with repair synthesis, converts NER intermediates to long ssDNA gaps, and promotes checkpoint activation. Mol Cell (2010) 1.33
The 9-1-1 checkpoint clamp physically interacts with polzeta and is partially required for spontaneous polzeta-dependent mutagenesis in Saccharomyces cerevisiae. J Biol Chem (2005) 1.31
Stabilization of RAD-51-DNA filaments via an interaction domain in Caenorhabditis elegans BRCA2. Proc Natl Acad Sci U S A (2007) 1.30
Replication blocking lesions present a unique substrate for homologous recombination. EMBO J (2007) 1.29
The centriolar satellite protein Cep131 is important for genome stability. J Cell Sci (2012) 1.27
RTEL1: an essential helicase for telomere maintenance and the regulation of homologous recombination. Nucleic Acids Res (2010) 1.27
RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication. Science (2013) 1.21
Loss and gain of domains during evolution of cut superclass homeobox genes. Int J Dev Biol (2002) 1.20
Checkpoint mechanisms at the intersection between DNA damage and repair. DNA Repair (Amst) (2009) 1.18
Requirements for F-BAR proteins TOCA-1 and TOCA-2 in actin dynamics and membrane trafficking during Caenorhabditis elegans oocyte growth and embryonic epidermal morphogenesis. PLoS Genet (2009) 1.14
C. elegans FANCD2 responds to replication stress and functions in interstrand cross-link repair. DNA Repair (Amst) (2006) 1.14
Tandem immunoaffinity purification of protein complexes from Caenorhabditis elegans. Biotechniques (2004) 1.13
Dynamics of Rad9 chromatin binding and checkpoint function are mediated by its dimerization and are cell cycle-regulated by CDK1 activity. PLoS Genet (2010) 1.12
Emerging links between the biological clock and the DNA damage response. Chromosoma (2007) 1.12
Yeast Rev1 is cell cycle regulated, phosphorylated in response to DNA damage and its binding to chromosomes is dependent upon MEC1. DNA Repair (Amst) (2006) 1.11
Meiotic recombination in Caenorhabditis elegans. Chromosome Res (2007) 1.08
Hedgehogs, humans and high-school science. The benefits of involving high-school students in university research. EMBO Rep (2008) 1.08
One-step high-throughput assay for quantitative detection of beta-galactosidase activity in intact gram-negative bacteria, yeast, and mammalian cells. Biotechniques (2006) 1.07
Joint molecule resolution requires the redundant activities of MUS-81 and XPF-1 during Caenorhabditis elegans meiosis. PLoS Genet (2013) 1.06
A recessive founder mutation in regulator of telomere elongation helicase 1, RTEL1, underlies severe immunodeficiency and features of Hoyeraal Hreidarsson syndrome. PLoS Genet (2013) 1.05
Mind the gap: keeping UV lesions in check. DNA Repair (Amst) (2011) 1.05
Human exonuclease 1 connects nucleotide excision repair (NER) processing with checkpoint activation in response to UV irradiation. Proc Natl Acad Sci U S A (2011) 1.02
The DNA polymerase alpha-primase complex: multiple functions and interactions. ScientificWorldJournal (2003) 0.99
Abrogation of the CLK-2 checkpoint leads to tolerance to base-excision repair intermediates. EMBO Rep (2006) 0.98
BRC-1 acts in the inter-sister pathway of meiotic double-strand break repair. EMBO Rep (2008) 0.97
Elevated levels of the polo kinase Cdc5 override the Mec1/ATR checkpoint in budding yeast by acting at different steps of the signaling pathway. PLoS Genet (2010) 0.96
Tetracycline and its analogues protect Caenorhabditis elegans from β amyloid-induced toxicity by targeting oligomers. Neurobiol Dis (2010) 0.96
Sensing of replication stress and Mec1 activation act through two independent pathways involving the 9-1-1 complex and DNA polymerase ε. PLoS Genet (2011) 0.95
Condensin, cohesin and the control of chromatin states. Curr Opin Genet Dev (2013) 0.95
NER and DDR: classical music with new instruments. Cell Cycle (2012) 0.94
The MRT-1 nuclease is required for DNA crosslink repair and telomerase activity in vivo in Caenorhabditis elegans. EMBO J (2009) 0.93
C. elegans: a model of Fanconi anemia and ICL repair. Mutat Res (2008) 0.92
PRDE-1 is a nuclear factor essential for the biogenesis of Ruby motif-dependent piRNAs in C. elegans. Genes Dev (2014) 0.91
Cell fate-specific regulation of EGF receptor trafficking during Caenorhabditis elegans vulval development. EMBO J (2006) 0.91