Published in Transplant Proc on October 01, 1987
Nitration and inactivation of manganese superoxide dismutase in chronic rejection of human renal allografts. Proc Natl Acad Sci U S A (1996) 2.77
Rapidly proliferative arteriopathy in cyclosporin-induced permanently surviving rat cardiac allografts simulating chronic vascular rejection. Clin Exp Immunol (1990) 0.75
Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus. Nature (1983) 8.60
Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling. Nature (1997) 7.69
Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor. J Biol Chem (1994) 6.18
Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities. Genes Dev (1994) 5.66
EULAR recommendations for the management of early arthritis: report of a task force of the European Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT). Ann Rheum Dis (2006) 4.83
cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines. Nature (1986) 4.81
Growth factors: mechanism of action and relation to oncogenes. Cell (1984) 4.80
Stimulation of tyrosine-specific phosphorylation by platelet-derived growth factor. Nature (1982) 4.74
Incidence of cancer among patients with rheumatoid arthritis. J Natl Cancer Inst (1993) 4.59
Improvement of an "In-Gel" digestion procedure for the micropreparation of internal protein fragments for amino acid sequencing. Anal Biochem (1995) 4.49
TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4. EMBO J (1997) 4.48
Quantification of the influence of cigarette smoking on rheumatoid arthritis: results from a population based case-control study, using incident cases. Ann Rheum Dis (2003) 4.36
Current status of clinical islet transplantation. Transplantation (2005) 4.17
Smad regulation in TGF-beta signal transduction. J Cell Sci (2001) 3.99
Latent high molecular weight complex of transforming growth factor beta 1. Purification from human platelets and structural characterization. J Biol Chem (1988) 3.98
Signal transduction via platelet-derived growth factor receptors. Biochim Biophys Acta (1998) 3.86
PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor. Nat Cell Biol (2000) 3.81
Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor. Nature (1989) 3.80
Activation of p70/p85 S6 kinase by a pathway independent of p21ras. Nature (1994) 3.67
Cloning of a TGF beta type I receptor that forms a heteromeric complex with the TGF beta type II receptor. Cell (1993) 3.57
Epidermal Langerhans cells express Ia antigens. Nature (1977) 3.51
Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4. J Biol Chem (1994) 3.49
TGF-(beta) type I receptor/ALK-5 and Smad proteins mediate epithelial to mesenchymal transdifferentiation in NMuMG breast epithelial cells. J Cell Sci (1999) 3.43
Treatment with infliximab (Remicade) when etanercept (Enbrel) has failed or vice versa: data from the STURE registry showing that switching tumour necrosis factor alpha blockers can make sense. Ann Rheum Dis (2003) 3.43
Golimumab, a human antibody to tumour necrosis factor {alpha} given by monthly subcutaneous injections, in active rheumatoid arthritis despite methotrexate therapy: the GO-FORWARD Study. Ann Rheum Dis (2008) 3.42
Specificity, diversity, and regulation in TGF-beta superfamily signaling. FASEB J (1999) 3.28
Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-beta, activin, and bone morphogenetic protein-inducible enhancer. J Biol Chem (1998) 3.23
Binding of different dimeric forms of PDGF to human fibroblasts: evidence for two separate receptor types. EMBO J (1988) 3.16
Platelet-derived growth factor and its receptors in human glioma tissue: expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops. Cancer Res (1992) 3.15
Does bullying cause emotional problems? A prospective study of young teenagers. BMJ (2001) 3.04
Platelet-derived growth factor: purification and partial characterization. Proc Natl Acad Sci U S A (1979) 3.04
Specific receptors for platelet-derived growth factor on cells derived from connective tissue and glia. Proc Natl Acad Sci U S A (1981) 3.02
Use of automated sequencing of polymerase chain reaction-generated amplicons to identify three types of cholera toxin subunit B in Vibrio cholerae O1 strains. J Clin Microbiol (1993) 3.01
The L45 loop in type I receptors for TGF-beta family members is a critical determinant in specifying Smad isoform activation. FEBS Lett (1998) 3.00
Characterization of type I receptors for transforming growth factor-beta and activin. Science (1994) 2.94
cDNA cloning and expression of a human platelet-derived growth factor (PDGF) receptor specific for B-chain-containing PDGF molecules. Mol Cell Biol (1988) 2.88
Reverse ELISPOT assay for clonal analysis of cytokine production. I. Enumeration of gamma-interferon-secreting cells. J Immunol Methods (1988) 2.84
Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors. Cancer Res (2001) 2.79
The c-sis gene encodes a precursor of the B chain of platelet-derived growth factor. EMBO J (1984) 2.77
Production of tissue factor by pancreatic islet cells as a trigger of detrimental thrombotic reactions in clinical islet transplantation. Lancet (2002) 2.76
Scandiatransplant: thirty years of cooperation in organ transplantation in the Nordic countries. Clin Transpl (1998) 2.73
A role of the latent TGF-beta 1-binding protein in the assembly and secretion of TGF-beta 1. EMBO J (1991) 2.73
PDGF-D is a specific, protease-activated ligand for the PDGF beta-receptor. Nat Cell Biol (2001) 2.70
Co-localization of NG2 proteoglycan and PDGF alpha-receptor on O2A progenitor cells in the developing rat brain. J Neurosci Res (1996) 2.67
Disease remission and sustained halting of radiographic progression with combination etanercept and methotrexate in patients with rheumatoid arthritis. Arthritis Rheum (2007) 2.66
Suppressors of SNF2 mutations restore invertase derepression and cause temperature-sensitive lethality in yeast. Genetics (1986) 2.64
Longitudinal analysis of citrullinated protein/peptide antibodies (anti-CP) during 5 year follow up in early rheumatoid arthritis: anti-CP status predicts worse disease activity and greater radiological progression. Ann Rheum Dis (2005) 2.62
Dimerization of B-type platelet-derived growth factor receptors occurs after ligand binding and is closely associated with receptor kinase activation. J Biol Chem (1989) 2.59
A human osteosarcoma cell line secretes a growth factor structurally related to a homodimer of PDGF A-chains. Nature (1986) 2.58
Characterization of the antibody response in mice with type II collagen-induced arthritis, using monoclonal anti-type II collagen antibodies. Arthritis Rheum (1986) 2.56
Disease activity and risk of lymphoma in patients with rheumatoid arthritis: nested case-control study. BMJ (1998) 2.51
Comparison of variable region 3 sequences of human immunodeficiency virus type 1 from infected children with the RNA and DNA sequences of the virus populations of their mothers. Proc Natl Acad Sci U S A (1993) 2.49
Identification of two C-terminal autophosphorylation sites in the PDGF beta-receptor: involvement in the interaction with phospholipase C-gamma. EMBO J (1992) 2.47
TGF-beta signaling by Smad proteins. Adv Immunol (2000) 2.47
Identification of two juxtamembrane autophosphorylation sites in the PDGF beta-receptor; involvement in the interaction with Src family tyrosine kinases. EMBO J (1993) 2.46
High incidence of post-injury pneumonia in intensive care-treated trauma patients. Acta Anaesthesiol Scand (2013) 2.46
TGF-beta 1 binding protein: a component of the large latent complex of TGF-beta 1 with multiple repeat sequences. Cell (1990) 2.46
Risks of solid cancers in patients with rheumatoid arthritis and after treatment with tumour necrosis factor antagonists. Ann Rheum Dis (2005) 2.46
Haematopoietic malignancies in rheumatoid arthritis: lymphoma risk and characteristics after exposure to tumour necrosis factor antagonists. Ann Rheum Dis (2005) 2.43
PDZ domains bind carboxy-terminal sequences of target proteins. Trends Biochem Sci (1996) 2.42
Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-beta signaling. J Biol Chem (1997) 2.39
Osteogenic protein-1 binds to activin type II receptors and induces certain activin-like effects. J Cell Biol (1995) 2.36
cDNA cloning and expression of the human A-type platelet-derived growth factor (PDGF) receptor establishes structural similarity to the B-type PDGF receptor. Proc Natl Acad Sci U S A (1989) 2.33
Rapid increase in myocardial infarction risk following diagnosis of rheumatoid arthritis amongst patients diagnosed between 1995 and 2006. J Intern Med (2010) 2.30
Expression of messenger RNAs for platelet-derived growth factor and transforming growth factor-alpha and their receptors in human malignant glioma cell lines. Cancer Res (1988) 2.28
Features of the synovium of individuals at risk of developing rheumatoid arthritis: implications for understanding preclinical rheumatoid arthritis. Arthritis Rheumatol (2014) 2.28
Membrane ruffling and chemotaxis transduced by the PDGF beta-receptor require the binding site for phosphatidylinositol 3' kinase. Oncogene (1994) 2.27
Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells. Ann Rheum Dis (2008) 2.27
Substrate adhesion of rat hepatocytes: mechanism of attachment to collagen substrates. Cell (1981) 2.26
Identification of novel phosphorylation sites in hormone-sensitive lipase that are phosphorylated in response to isoproterenol and govern activation properties in vitro. J Biol Chem (1998) 2.25
Citrullination is an inflammation-dependent process. Ann Rheum Dis (2006) 2.25
Signaling inputs converge on nuclear effectors in TGF-beta signaling. Trends Biochem Sci (2000) 2.24
Activin receptor-like kinases: a novel subclass of cell-surface receptors with predicted serine/threonine kinase activity. Oncogene (1993) 2.19
Partial purification and characterization of platelet factors stimulating the multiplication of normal human glial cells. Exp Cell Res (1977) 2.19
Cloning and characterization of a human type II receptor for bone morphogenetic proteins. Proc Natl Acad Sci U S A (1995) 2.19
Fibronectin receptors from Staphylococcus aureus. J Biol Chem (1983) 2.19
Modulation of CCR2 in rheumatoid arthritis: a double-blind, randomized, placebo-controlled clinical trial. Arthritis Rheum (2008) 2.17
Improved cortisol exposure-time profile and outcome in patients with adrenal insufficiency: a prospective randomized trial of a novel hydrocortisone dual-release formulation. J Clin Endocrinol Metab (2011) 2.16
Oligodendrocyte progenitors are present in the normal adult human CNS and in the lesions of multiple sclerosis. Brain (1998) 2.16
Latent transforming growth factor-beta 1 associates to fibroblast extracellular matrix via latent TGF-beta binding protein. J Cell Biol (1994) 2.15
Biological and molecular characterization of subtype D, G, and A/D recombinant HIV-1 transmissions in Sweden. Virology (1995) 2.07
Consensus statement on the use of rituximab in patients with rheumatoid arthritis. Ann Rheum Dis (2006) 2.07
Coexpression of the sis and myc proto-oncogenes in developing human placenta suggests autocrine control of trophoblast growth. Cell (1985) 2.06
Purification and properties of an endothelial cell growth factor from human platelets. J Biol Chem (1987) 2.06
Interaction of platelet-derived growth factor with its fibroblast receptor. Demonstration of ligand degradation and receptor modulation. J Biol Chem (1982) 2.03
Role for carbohydrate structures in TGF-beta 1 latency. Nature (1989) 2.02
Appearance of anti-HLA-DR-reactive cells in normal and rheumatoid synovial tissue. Scand J Immunol (1981) 2.02
Platelet-derived growth factor: identification of constituent polypeptide chains. Biochem Biophys Res Commun (1982) 2.00
Coexpression of a PDGF-like growth factor and PDGF receptors in a human osteosarcoma cell line: implications for autocrine receptor activation. Cell (1984) 1.99
Evidence in support of a self-perpetuating HLA-DR-dependent delayed-type cell reaction in rheumatoid arthritis. Proc Natl Acad Sci U S A (1982) 1.99
A glioma-derived PDGF A chain homodimer has different functional activities from a PDGF AB heterodimer purified from human platelets. Cell (1988) 1.99
Platelet-derived growth factor. Isolation by a large-scale procedure and analysis of subunit composition. Biochem J (1981) 1.97
T lymphocytes in collagen II-induced arthritis in mice. Characterization of arthritogenic collagen II-specific T-cell lines and clones. Scand J Immunol (1985) 1.96