Analysis of a cAMP regulated coactivator family reveals an alternative phosphorylation motif for AMPK family members.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 28235073)

Published in PLoS One on February 24, 2017

Authors

Tim Sonntag1, James J Moresco2, Joan M Vaughan1, Shigenobu Matsumura3, John R Yates2, Marc Montminy1

Author Affiliations

1: Clayton Foundation Laboratories for Peptide Biology, The Salk Institute for Biological Studies, La Jolla, California, United States of America.
2: Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California, United States of America.
3: Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Oiwake-cho, Kitashirakawa, Sakyo-ku, Kyoto, Japan.

Articles cited by this

Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs. Nucleic Acids Res (2003) 15.74

DTASelect and Contrast: tools for assembling and comparing protein identifications from shotgun proteomics. J Proteome Res (2003) 12.31

A probability-based approach for high-throughput protein phosphorylation analysis and site localization. Nat Biotechnol (2006) 12.13

Evaluation of multidimensional chromatography coupled with tandem mass spectrometry (LC/LC-MS/MS) for large-scale protein analysis: the yeast proteome. J Proteome Res (2003) 11.96

The structural basis for 14-3-3:phosphopeptide binding specificity. Cell (1997) 10.87

The LKB1-AMPK pathway: metabolism and growth control in tumour suppression. Nat Rev Cancer (2009) 8.43

The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism. Nature (2005) 7.14

14-3-3 proteins: structure, function, and regulation. Annu Rev Pharmacol Toxicol (2000) 6.94

An automated multidimensional protein identification technology for shotgun proteomics. Anal Chem (2001) 6.90

The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector. Cell (2004) 4.91

MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption. Cell (1997) 4.75

TORCs: transducers of regulated CREB activity. Mol Cell (2003) 4.42

CREB and the CRTC co-activators: sensors for hormonal and metabolic signals. Nat Rev Mol Cell Biol (2011) 4.12

How do 14-3-3 proteins work?-- Gatekeeper phosphorylation and the molecular anvil hypothesis. FEBS Lett (2002) 4.08

An efficient tandem affinity purification procedure for interaction proteomics in mammalian cells. Nat Methods (2006) 3.38

Activation of cAMP response element-mediated gene expression by regulated nuclear transport of TORC proteins. Curr Biol (2004) 2.69

PhosphoSitePlus, 2014: mutations, PTMs and recalibrations. Nucleic Acids Res (2014) 2.66

SIK1 is a class II HDAC kinase that promotes survival of skeletal myocytes. Nat Med (2007) 2.17

The Creb1 coactivator Crtc1 is required for energy balance and fertility. Nat Med (2008) 1.87

14-3-3 proteins--an update. Cell Res (2005) 1.73

Bioinformatic and experimental survey of 14-3-3-binding sites. Biochem J (2010) 1.73

NEK1 mutations cause short-rib polydactyly syndrome type majewski. Am J Hum Genet (2011) 1.56

Glucose controls CREB activity in islet cells via regulated phosphorylation of TORC2. Proc Natl Acad Sci U S A (2008) 1.56

Analysis of an activator:coactivator complex reveals an essential role for secondary structure in transcriptional activation. Mol Cell (1998) 1.56

CRTC3 links catecholamine signalling to energy balance. Nature (2010) 1.55

Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages. Proc Natl Acad Sci U S A (2012) 1.52

Helicobacter pylori CagA inhibits PAR1-MARK family kinases by mimicking host substrates. Nat Struct Mol Biol (2009) 1.28

Identification of Evening Complex Associated Proteins in Arabidopsis by Affinity Purification and Mass Spectrometry. Mol Cell Proteomics (2015) 1.21

Never-in-mitosis related kinase 1 functions in DNA damage response and checkpoint control. Cell Cycle (2008) 1.18

Salt-inducible kinase-1 represses cAMP response element-binding protein activity both in the nucleus and in the cytoplasm. Eur J Biochem (2004) 1.18

Activity-dependent transport of the transcriptional coactivator CRTC1 from synapse to nucleus. Cell (2012) 1.17

NEK1 variants confer susceptibility to amyotrophic lateral sclerosis. Nat Genet (2016) 1.16

Mechanism of CREB recognition and coactivation by the CREB-regulated transcriptional coactivator CRTC2. Proc Natl Acad Sci U S A (2012) 1.08

The tumor suppressor kinase LKB1 activates the downstream kinases SIK2 and SIK3 to stimulate nuclear export of class IIa histone deacetylases. J Biol Chem (2013) 1.08

ProLuCID: An improved SEQUEST-like algorithm with enhanced sensitivity and specificity. J Proteomics (2015) 1.07

The AMPK-related kinase SIK2 is regulated by cAMP via phosphorylation at Ser358 in adipocytes. Biochem J (2012) 0.98

The CRTC1-SIK1 pathway regulates entrainment of the circadian clock. Cell (2013) 0.97

SIK2 regulates CRTCs, HDAC4 and glucose uptake in adipocytes. J Cell Sci (2015) 0.90

cAMP-elevation mediated by β-adrenergic stimulation inhibits salt-inducible kinase (SIK) 3 activity in adipocytes. Cell Signal (2012) 0.86

Identification of AMPK Phosphorylation Sites Reveals a Network of Proteins Involved in Cell Invasion and Facilitates Large-Scale Substrate Prediction. Cell Metab (2015) 0.85

An intein-cassette integration approach used for the generation of a split TEV protease activated by conditional protein splicing. Mol Biosyst (2011) 0.84

Nek1 Regulates Rad54 to Orchestrate Homologous Recombination and Replication Fork Stability. Mol Cell (2016) 0.84

Extracting Accurate Precursor Information for Tandem Mass Spectra by RawConverter. Anal Chem (2015) 0.81

Protein kinase A rescues microtubule affinity-regulating kinase 2-induced microtubule instability and neurite disruption by phosphorylating serine 409. J Biol Chem (2014) 0.77