Structural alteration in the MYB protooncogene and deletion within the gene encoding alpha-type protein kinase C in human melanoma cell lines.

PubWeight™: 1.00‹?› | Rank: Top 15%

🔗 View Article (PMC 279484)

Published in Proc Natl Acad Sci U S A on January 01, 1988

Authors

A J Linnenbach1, K Huebner, E P Reddy, M Herlyn, A H Parmiter, P C Nowell, H Koprowski

Author Affiliations

1: Wistar Institute, Philadelphia, PA 19104.

Articles cited by this

Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol (1975) 503.08

Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose. Proc Natl Acad Sci U S A (1972) 83.88

RNA molecular weight determinations by gel electrophoresis under denaturing conditions, a critical reexamination. Biochemistry (1977) 38.82

Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene. Science (1985) 9.12

Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin. Nature (1985) 8.23

Involvement of the bcl-2 gene in human follicular lymphoma. Science (1985) 8.19

Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour. Nature (1983) 8.18

Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors. Nature (1986) 7.90

Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity. EMBO J (1986) 6.62

Nucleotide sequence of the retroviral leukemia gene v-myb and its cellular progenitor c-myb: the architecture of a transduced oncogene. Cell (1982) 6.19

Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways. Science (1986) 6.10

Inhibition of intractable nucleases with ribonucleoside--vanadyl complexes: isolation of messenger ribonucleic acid from resting lymphocytes. Biochemistry (1979) 6.00

Molecular cloning of a new transforming gene from a chemically transformed human cell line. Nature (1984) 5.85

Structure and activation of the human N-ras gene. Cell (1983) 5.25

cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines. Nature (1986) 4.81

L-myc, a new myc-related gene amplified and expressed in human small cell lung cancer. Nature (1985) 4.66

The complete primary structure of protein kinase C--the major phorbol ester receptor. Science (1986) 4.02

Isolation of the human insulin-like growth factor I gene using a single synthetic DNA probe. EMBO J (1984) 3.74

Nucleotide sequence of epidermal growth factor cDNA predicts a 128,000-molecular weight protein precursor. Nature (1983) 3.43

A study of tumor progression: the precursor lesions of superficial spreading and nodular melanoma. Hum Pathol (1984) 3.21

Human p53 cellular tumor antigen: cDNA sequence and expression in COS cells. EMBO J (1985) 3.18

Human beta-nerve growth factor gene sequence highly homologous to that of mouse. Nature (1983) 3.17

Two modes of c-myb activation in virus-induced mouse myeloid tumors. Mol Cell Biol (1986) 2.57

Acquired precursors of cutaneous malignant melanoma. The familial dysplastic nevus syndrome. N Engl J Med (1985) 2.54

Expression of epidermal growth factor receptors on human cervical, ovarian, and vulval carcinomas. Cancer Res (1986) 2.38

Human epidermal growth factor receptor cDNA is homologous to a variety of RNAs overproduced in A431 carcinoma cells. Nature (1984) 2.36

Transforming ras genes from human melanoma: a manifestation of tumour heterogeneity? Nature (1984) 2.14

Molecular cloning and the total nucleotide sequence of the human c-Ha-ras-1 gene activated in a melanoma from a Japanese patient. Proc Natl Acad Sci U S A (1984) 1.95

Role of chromosome translocations in human neoplasia. Cell (1987) 1.94

Gene transfer and molecular cloning of the human NGF receptor. Science (1986) 1.91

The structure and nucleotide sequence of the 5' end of the human c-myc oncogene. Proc Natl Acad Sci U S A (1983) 1.84

Purification of melanoma growth stimulatory activity. J Cell Physiol (1986) 1.73

Familial cutaneous malignant melanoma: autosomal dominant trait possibly linked to the Rh locus. Proc Natl Acad Sci U S A (1983) 1.72

A novel transforming gene in a human malignant melanoma cell line. Nature (1984) 1.63

Integration of transfected LTR sequences into the c-raf proto-oncogene: activation by promoter insertion. EMBO J (1985) 1.60

Aberrant expression of an amplified c-myb oncogene in two cell lines from a colon carcinoma. Proc Natl Acad Sci U S A (1984) 1.59

Amplification of the c-myb oncogene in a case of human acute myelogenous leukemia. Science (1984) 1.56

Regional chromosomal localization of N-ras, K-ras-1, K-ras-2 and myb oncogenes in human cells. Nucleic Acids Res (1983) 1.41

Cutaneous malignant melanoma and familial dysplastic nevi: evidence for autosomal dominance and pleiotropy. Am J Hum Genet (1986) 1.39

Karyotypic evolution in human malignant melanoma. Cancer Genet Cytogenet (1986) 1.34

Activation of N-ras in a human melanoma cell line. Mol Cell Biol (1985) 1.30

Localization of the human pim oncogene (PIM) to a region of chromosome 6 involved in translocations in acute leukemias. Proc Natl Acad Sci U S A (1986) 1.20

Nucleotide sequence of transforming human c-sis cDNA clones with homology to platelet-derived growth factor. Nucleic Acids Res (1985) 1.18

Cytogenetics of human malignant melanoma and premalignant lesions. Cancer Genet Cytogenet (1984) 1.15

The human c-ros gene (ROS) is located at chromosome region 6q16----6q22. Proc Natl Acad Sci U S A (1986) 1.12

Actively transcribed genes in the raf oncogene group, located on the X chromosome in mouse and human. Proc Natl Acad Sci U S A (1986) 1.09

Chromosomal assignment of c-MEL, a human transforming oncogene, to chromosome 19 (p13.2-q13.2). Somat Cell Mol Genet (1986) 1.09

Melanoma antigens: immunological and biological characterization and clinical significance. Annu Rev Immunol (1988) 1.08

Relationship between the c-myb locus and the 6q-chromosomal aberration in leukemias and lymphomas. Science (1987) 0.98

A t(1;19) chromosome translocation in three cases of human malignant melanoma. Cancer Res (1986) 0.97

Expression of the receptor for epidermal growth factor correlates with increased dosage of chromosome 7 in malignant melanoma. Somat Cell Mol Genet (1985) 0.95

Molecular cloning and chromosomal assignment of the human homolog of int-1, a mouse gene implicated in mammary tumorigenesis. Mol Cell Biol (1984) 0.95

Nonrandom chromosome structural aberrations and oncogene loci in human malignant melanoma. Cancer Genet Cytogenet (1986) 0.91

Nonrandom chromosome changes in malignant melanoma. Cancer Res (1983) 0.87

Ectopic peptides released by a human melanoma cell line that modulate the transformed phenotype. Proc Natl Acad Sci U S A (1985) 0.86

Chromosome 6q involvement in human malignant melanoma. Cancer Genet Cytogenet (1983) 0.84

Chromosome 6 in malignant melanoma. Cancer Genet Cytogenet (1983) 0.77

Cytogenetic findings in a malignant melanoma and its derived cell line. Cancer Genet Cytogenet (1986) 0.77

Articles by these authors

The clonal evolution of tumor cell populations. Science (1976) 24.39

The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers. Cell (1996) 15.19

A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene. Nature (1982) 11.92

Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation. Science (1984) 8.80

Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia. Nat Genet (1999) 8.53

Colorectal carcinoma antigens detected by hybridoma antibodies. Somatic Cell Genet (1979) 7.28

Activation of production of infectious tumor virus SV40 in heterokaryon cultures. Proc Natl Acad Sci U S A (1967) 6.05

Molecular cloning of a new transforming gene from a chemically transformed human cell line. Nature (1984) 5.85

Expression of cellular homologues of retroviral onc genes in human hematopoietic cells. Proc Natl Acad Sci U S A (1982) 5.80

Cellular genes analogous to retroviral onc genes are transcribed in human tumour cells. Nature (1982) 5.11

Alterations in T4 (CD4) protein and mRNA synthesis in cells infected with HIV. Science (1986) 4.79

JNK signaling in apoptosis. Oncogene (2008) 4.72

Characterization of an antigenic determinant of the glycoprotein that correlates with pathogenicity of rabies virus. Proc Natl Acad Sci U S A (1983) 4.54

Chromosomal location of the genes for human immunoglobulin heavy chains. Proc Natl Acad Sci U S A (1979) 4.52

Acquisition of transforming properties by alternative point mutations within c-bas/has human proto-oncogene. Nature (1983) 4.34

Nucleotide sequence of Abelson murine leukemia virus genome: structural similarity of its transforming gene product to other onc gene products with tyrosine-specific kinase activity. Proc Natl Acad Sci U S A (1983) 4.32

Production of antibodies against influenza virus by somatic cell hybrids between mouse myeloma and primed spleen cells. Proc Natl Acad Sci U S A (1977) 4.30

Trends in the postmortem epidemiology of invasive fungal infections at a university hospital. J Infect (1996) 4.26

Study of antibodies against human melanoma produced by somatic cell hybrids. Proc Natl Acad Sci U S A (1978) 4.24

Integrin distribution in malignant melanoma: association of the beta 3 subunit with tumor progression. Cancer Res (1990) 4.22

Mixed hematopoietic and pulmonary origin of 'alveolar macrophages' as demonstrated by chromosome markers. Am J Pathol (1966) 4.08

Nucleotide sequence analysis of the chicken c-myc gene reveals homologous and unique coding regions by comparison with the transforming gene of avian myelocytomatosis virus MC29, delta gag-myc. Proc Natl Acad Sci U S A (1983) 4.06

A monoclonal antibody-defined antigen associated with gastrointestinal cancer is a ganglioside containing sialylated lacto-N-fucopentaose II. J Biol Chem (1982) 3.97

Cell cycle control in mammalian cells: role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs). Oncogene (1995) 3.96

Quantitative studies on the mixed lymphocyte interaction in rats. II. Relationship of the proliferative response to the immunologic status of the donors. J Exp Med (1967) 3.82

Translocation of an immunoglobulin kappa locus to a region 3' of an unrearranged c-myc oncogene enhances c-myc transcription. Proc Natl Acad Sci U S A (1983) 3.75

Specific antigen in serum of patients with colon carcinoma. Science (1981) 3.68

Molecular cloning of the chromosomal breakpoint of B-cell lymphomas and leukemias with the t(11;14) chromosome translocation. Science (1984) 3.64

Transcriptional activation of an unrearranged and untranslocated c-myc oncogene by translocation of a C lambda locus in Burkitt. Proc Natl Acad Sci U S A (1983) 3.53

Colorectal carcinoma-specific antigen: detection by means of monoclonal antibodies. Proc Natl Acad Sci U S A (1979) 3.46

Transcriptional activation of the translocated c-myc oncogene in burkitt lymphoma. Proc Natl Acad Sci U S A (1983) 3.46

Nucleotide sequence analysis of the proviral genome of avian myelocytomatosis virus (MC29). Proc Natl Acad Sci U S A (1983) 3.43

Adenovirus 5 DNA sequences present and RNA sequences transcribed in transformed human embryo kidney cells (HEK-Ad-5 or 293). Virology (1979) 3.34

Expression of rabies virus glycoprotein from a recombinant vaccinia virus. Nature (1984) 3.32

Translocation of immunoglobulin VH genes in Burkitt lymphoma. Proc Natl Acad Sci U S A (1982) 3.30

The myb gene family in cell growth, differentiation and apoptosis. Oncogene (1999) 3.28

Comparison of the ribonucleic acid polymerases of two rhabdoviruses, Kern Canyon virus and vesicular stomatitis virus. J Virol (1971) 3.26

Effect of cell chromosome number on simian virus 40 replication. Exp Cell Res (1973) 3.20

Sequential expression of protooncogenes during lectin-stimulated mitogenesis of normal human lymphocytes. Proc Natl Acad Sci U S A (1986) 3.19

Identification of the gastrointestinal and pancreatic cancer-associated antigen detected by monoclonal antibody 19-9 in the sera of patients as a mucin. Cancer Res (1983) 3.15

Nucleotide sequence of the transforming gene of avian myeloblastosis virus. Science (1982) 3.12

HTLV-III gag protein is processed in yeast cells by the virus pol-protease. Science (1986) 3.06

Gene product of v-fgr onc: hybrid protein containing a portion of actin and a tyrosine-specific protein kinase. Science (1984) 3.06

Monoclonal antibodies against rabies virus produced by somatic cell hybridization: detection of antigenic variants. Proc Natl Acad Sci U S A (1978) 3.03

Characterization of the mammalian YAP (Yes-associated protein) gene and its role in defining a novel protein module, the WW domain. J Biol Chem (1995) 3.01

Progenitor/stem cells give rise to liver cancer due to aberrant TGF-beta and IL-6 signaling. Proc Natl Acad Sci U S A (2008) 2.98

Malignant activation of a K-ras oncogene in lung carcinoma but not in normal tissue of the same patient. Science (1984) 2.97

Nucleotide sequence of the simian sarcoma virus genome: demonstration that its acquired cellular sequences encode the transforming gene product p28sis. Proc Natl Acad Sci U S A (1983) 2.95

Nucleotide sequence analysis of the transforming region and large terminal redundancies of Moloney murine sarcoma virus. Proc Natl Acad Sci U S A (1980) 2.93

Clustering of breakpoints on chromosome 11 in human B-cell neoplasms with the t(11;14) chromosome translocation. Nature (1985) 2.91

Meis1, a PBX1-related homeobox gene involved in myeloid leukemia in BXH-2 mice. Mol Cell Biol (1995) 2.89

Structure and expression pattern of human ALR, a novel gene with strong homology to ALL-1 involved in acute leukemia and to Drosophila trithorax. Oncogene (1997) 2.69

Antigenic properties of rabies virus components. J Immunol (1973) 2.68

Purification of rabies virus grown in tissue culture. J Virol (1968) 2.67

Effect of polyions on the infectivity of rabies virus in tissue culture: construction of a single-cycle growth curve. J Virol (1967) 2.67

New assay procedure for separation of mycoplasmas from virus pools and tissue culture systems. J Virol (1967) 2.64

Assignment of the T-antigen gene of simian virus 40 to human chromosome C-7. Proc Natl Acad Sci U S A (1973) 2.63

Mechanisms of tumor progression. Cancer Res (1986) 2.62

Detection of serum antibodies to Borna disease virus in patients with psychiatric disorders. Science (1985) 2.57

Isolation of latent herpes simplex virus from the superior cervical and vagus ganglions of human beings. N Engl J Med (1978) 2.55

The alpha-spectrin gene is on chromosome 1 in mouse and man. Proc Natl Acad Sci U S A (1985) 2.53

Complete nucleotide sequence and organization of the Moloney murine sarcoma virus genome. Science (1981) 2.51

Antigenic variants of rabies virus. J Exp Med (1980) 2.51

elk, tissue-specific ets-related genes on chromosomes X and 14 near translocation breakpoints. Science (1989) 2.48

N-cadherin-mediated intercellular interactions promote survival and migration of melanoma cells. Cancer Res (2001) 2.47

Successful protection of humans exposed to rabies infection. Postexposure treatment with the new human diploid cell rabies vaccine and antirabies serum. JAMA (1976) 2.47

Fhit, a putative tumor suppressor in humans, is a dinucleoside 5',5"'-P1,P3-triphosphate hydrolase. Biochemistry (1996) 2.46

Herpes simplex type 1 DNA in human brain tissue. Proc Natl Acad Sci U S A (1981) 2.45

Involvement of the TCL5 gene on human chromosome 1 in T-cell leukemia and melanoma. Proc Natl Acad Sci U S A (1989) 2.45

Truncation of the c-myb gene by a retroviral integration in an interleukin 3-dependent myeloid leukemia cell line. Proc Natl Acad Sci U S A (1986) 2.43

Structural proteins of rabies virus. J Virol (1971) 2.42

Papillomavirus sequences integrate near cellular oncogenes in some cervical carcinomas. Proc Natl Acad Sci U S A (1987) 2.40

DNA rearrangement and altered RNA expression of the c-myb oncogene in mouse plasmacytoid lymphosarcomas. Science (1983) 2.40

Effect of environmental pH on the efficiency of cellular hybridization. Proc Natl Acad Sci U S A (1972) 2.39

Repertoire of antiviral antibodies expressed by somatic cell hybrids. Proc Natl Acad Sci U S A (1978) 2.38

The FHIT gene 3p14.2 is abnormal in lung cancer. Cell (1996) 2.36

Replacement of Fhit in cancer cells suppresses tumorigenicity. Proc Natl Acad Sci U S A (1997) 2.36

E-cadherin expression in melanoma cells restores keratinocyte-mediated growth control and down-regulates expression of invasion-related adhesion receptors. Am J Pathol (2000) 2.36

Regulation of bcl-2 proto-oncogene expression during normal human lymphocyte proliferation. Science (1987) 2.36

Abelson murine leukemia virus: molecular cloning of infectious integrated proviral DNA. Proc Natl Acad Sci U S A (1981) 2.34

A novel endothelial cell surface receptor tyrosine kinase with extracellular epidermal growth factor homology domains. Mol Cell Biol (1992) 2.34

Production of human hybridomas secreting antibodies to measles virus. Nature (1980) 2.32

Scaffold proteins of MAP-kinase modules. Oncogene (2007) 2.30

Activation of the c-myb locus by viral insertional mutagenesis in plasmacytoid lymphosarcomas. Science (1984) 2.28

Liver stem cells and hepatocellular carcinoma. Hepatology (2009) 2.27

Cloning and sequencing of cDNA encoding human DNA topoisomerase II and localization of the gene to chromosome region 17q21-22. Proc Natl Acad Sci U S A (1988) 2.26

Immune lysis of rabies virus-infected cells. J Immunol (1968) 2.25

Phase-I clinical trial of monoclonal antibody in treatment of gastrointestinal tumours. Lancet (1982) 2.25

Influenza virus hemagglutinin-specific antibodies isolated from a combinatorial expression library are closely related to the immune response of the donor. Proc Natl Acad Sci U S A (1990) 2.24

Melanoma cells and normal melanocytes share antigens recognized by HLA-A2-restricted cytotoxic T cell clones from melanoma patients. J Exp Med (1993) 2.24

Amplification and molecular cloning of HTLV-I sequences from DNA of multiple sclerosis patients. Science (1989) 2.23

Human melanoma progression in skin reconstructs : biological significance of bFGF. Am J Pathol (2000) 2.23

Molecular recognition and the future of monoclonal antibodies. Nature (1982) 2.22

Control of expression of histocompatibility antigens (H-2) and beta 2-microglobulin in F9 teratocarcinoma stem cells. Proc Natl Acad Sci U S A (1981) 2.22

Uric acid, a natural scavenger of peroxynitrite, in experimental allergic encephalomyelitis and multiple sclerosis. Proc Natl Acad Sci U S A (1998) 2.21

Selective suppression of the transcription of ribosomal genes in mouse-human hybrid cells. J Cell Physiol (1979) 2.21