Published in Proc Natl Acad Sci U S A on April 01, 1988
Physical mapping of the von Recklinghausen neurofibromatosis region on chromosome 17. Am J Hum Genet (1989) 1.54
Integrated genome and transcriptome sequencing identifies a novel form of hybrid and aggressive prostate cancer. J Pathol (2012) 1.07
Nucleotide sequence of both reciprocal translocation junction regions in a patient with Ph positive acute lymphoblastic leukaemia, with a breakpoint within the first intron of the BCR gene. Nucleic Acids Res (1989) 0.99
Localization of preferential sites of rearrangement within the BCR gene in Philadelphia chromosome-positive acute lymphoblastic leukemia. Proc Natl Acad Sci U S A (1989) 0.97
Unexpected heterogeneity of BCR-ABL fusion mRNA detected by polymerase chain reaction in Philadelphia chromosome-positive acute lymphoblastic leukemia. Proc Natl Acad Sci U S A (1989) 0.78
A deletion/insertion polymorphism in the human BCR gene on chromosome 22. Nucleic Acids Res (1988) 0.78
Etiological analysis of neurodevelopmental disabilities: single-center eight-year clinical experience in south China. J Biomed Biotechnol (2010) 0.75
A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem (1983) 206.01
Lambda replacement vectors carrying polylinker sequences. J Mol Biol (1983) 32.76
Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis. Cell (1984) 31.52
Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining. Nature (1973) 15.28
Separation of chromosomal DNA molecules from yeast by orthogonal-field-alternation gel electrophoresis. Nucleic Acids Res (1984) 14.43
Removal of repeated sequences from hybridisation probes. Nucleic Acids Res (1985) 9.79
Fused transcript of abl and bcr genes in chronic myelogenous leukaemia. Nature (1985) 8.32
Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22. Cell (1984) 6.78
Structural organization of the bcr gene and its role in the Ph' translocation. Nature (1985) 4.08
Alternative splicing of RNAs transcribed from the human abl gene and from the bcr-abl fused gene. Cell (1986) 3.59
The chronic myelogenous leukemia-specific P210 protein is the product of the bcr/abl hybrid gene. Science (1986) 3.53
In vitro transformation of immature hematopoietic cells by the P210 BCR/ABL oncogene product of the Philadelphia chromosome. Proc Natl Acad Sci U S A (1987) 3.03
Unique fusion of bcr and c-abl genes in Philadelphia chromosome positive acute lymphoblastic leukemia. Cell (1987) 2.27
Overlapping cDNA clones define the complete coding region for the P210c-abl gene product associated with chronic myelogenous leukemia cells containing the Philadelphia chromosome. Proc Natl Acad Sci U S A (1986) 1.97
Unique forms of the abl tyrosine kinase distinguish Ph1-positive CML from Ph1-positive ALL. Science (1987) 1.76
The first intron in the human c-abl gene is at least 200 kilobases long and is a target for translocations in chronic myelogenous leukemia. Mol Cell Biol (1987) 1.73
Establishment of a Ph1-positive human cell line (BV173). J Natl Cancer Inst (1983) 1.72
The chronic myelocytic cell line K562 contains a breakpoint in bcr and produces a chimeric bcr/c-abl transcript. Mol Cell Biol (1986) 1.72
A somatic cell hybrid with a single human chromosome 22 corrects the defect in the CHO mutant (Ade-I) lacking adenylosuccinase activity. Cytogenet Cell Genet (1987) 1.68
A novel c-abl protein product in Philadelphia-positive acute lymphoblastic leukaemia. Nature (1987) 1.61
A novel abl protein expressed in Philadelphia chromosome positive acute lymphoblastic leukaemia. Nature (1987) 1.56
Mapping of four distinct BCR-related loci to chromosome region 22q11: order of BCR loci relative to chronic myelogenous leukemia and acute lymphoblastic leukemia breakpoints. Proc Natl Acad Sci U S A (1987) 1.49
A new fused transcript in Philadelphia chromosome positive acute lymphocytic leukaemia. Nature (1987) 1.42
Heterogeneity of chromosome 22 breakpoint in Philadelphia-positive (Ph+) acute lymphocytic leukemia. Proc Natl Acad Sci U S A (1986) 1.41
Isolation and analysis of the 21q+ chromosome in the acute myelogenous leukemia 8;21 translocation: evidence that c-mos is not translocated. Proc Natl Acad Sci U S A (1985) 1.36
Novel chimaeric protein expressed in Philadelphia positive acute lymphoblastic leukaemia. Nature (1987) 1.16
bcr rearrangement and translocation of the c-abl oncogene in Philadelphia positive acute lymphoblastic leukemia. Blood (1986) 1.14
Ph1-positive acute leukaemia and chronic granulocytic leukaemia: one or two diseases? Br J Haematol (1979) 1.04
Molecular cloning of the breakpoint junction of a human chromosomal 8;14 translocation involving the T-cell receptor alpha-chain gene and sequences on the 3' side of MYC. Proc Natl Acad Sci U S A (1986) 1.01
Long-range mapping of the Philadelphia chromosome by pulsed-field gel electrophoresis. Blood (1988) 0.99
Molecular analysis of TCRB and ABL in a t(7;9)-containing cell line (SUP-T3) from a human T-cell leukemia. Proc Natl Acad Sci U S A (1987) 0.96
Variable breakpoints on the Philadelphia chromosome in chronic myelogenous leukemia. Blood (1985) 0.86
Molecular analysis of chromosome 22 breakpoints in adult Philadelphia-positive acute lymphoblastic leukaemia. Br J Haematol (1987) 0.79
TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell (1991) 10.06
Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation. Cell (1986) 7.34
Changes in restricted human cellular DNA fragments containing globin gene sequences in thalassemias and related disorders. Proc Natl Acad Sci U S A (1978) 6.46
Quantitative trait locus for reading disability on chromosome 6. Science (1994) 6.07
Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor. Cell (1990) 4.60
Diagnosis of chronic myeloid and acute lymphocytic leukemias by detection of leukemia-specific mRNA sequences amplified in vitro. Proc Natl Acad Sci U S A (1988) 4.40
Organization of human delta--and beta-globin genes in cellular DNA and the presence of intragenic inserts. Cell (1978) 4.18
Monoclonal antibody and enzymatic profiles of human malignant T-lymphoid cells and derived cell lines. Cancer Res (1984) 3.67
Homozygous deletion of the alpha- and beta 1-interferon genes in human leukemia and derived cell lines. Proc Natl Acad Sci U S A (1988) 3.67
Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias. Proc Natl Acad Sci U S A (1991) 3.25
lyl-1, a novel gene altered by chromosomal translocation in T cell leukemia, codes for a protein with a helix-loop-helix DNA binding motif. Cell (1989) 2.84
Localization of gelsolin proximal to ABL on chromosome 9. Am J Hum Genet (1988) 2.64
Transcription regulation of peroxisomal fatty acyl-CoA oxidase and enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase in rat liver by peroxisome proliferators. Proc Natl Acad Sci U S A (1986) 2.57
Novel mutations in the connexin 26 gene (GJB2) that cause autosomal recessive (DFNB1) hearing loss. Am J Hum Genet (1998) 2.51
Quantitative-trait locus for specific language and reading deficits on chromosome 6p. Am J Hum Genet (1999) 2.26
Molecular characterization and expression of the gene encoding human erythroid-potentiating activity. Nature (1985) 2.25
Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia. Science (1992) 2.19
TUNEL-positive ganglion cells in human primary open-angle glaucoma. Arch Ophthalmol (1997) 2.11
Linkage of autosomal dominant hearing loss to the short arm of chromosome 1 in two families. N Engl J Med (1994) 2.03
Differential phosphorylation and localization of the transcription factor UBF in vivo in response to serum deprivation. In vitro dephosphorylation of UBF reduces its transactivation properties. J Biol Chem (1992) 2.02
A reliable method for evaluating drug compliance in children with cancer. Cancer (1979) 2.00
Common region on chromosome 14 in T-cell leukemia and lymphoma. Science (1984) 1.98
Specific reading disability: identification of an inherited form through linkage analysis. Science (1983) 1.94
Evidence for two distinct c-src loci on human chromosomes 1 and 20. Nature (1984) 1.91
Evidence for the involvement of GM-CSF and FMS in the deletion (5q) in myeloid disorders. Science (1986) 1.91
Detection of bcr-abl fusion in chronic myelogeneous leukemia by in situ hybridization. Science (1990) 1.90
Genetic influences on learning disabilities and speech and language disorders. Child Dev (1983) 1.90
Fusion of an immunoglobulin variable gene and a T cell receptor constant gene in the chromosome 14 inversion associated with T cell tumors. Cell (1985) 1.87
Myotilin is mutated in limb girdle muscular dystrophy 1A. Hum Mol Genet (2000) 1.78
The first intron in the human c-abl gene is at least 200 kilobases long and is a target for translocations in chronic myelogenous leukemia. Mol Cell Biol (1987) 1.73
Analysis of the phosphorylation, DNA-binding and dimerization properties of the RNA polymerase I transcription factors UBF1 and UBF2. Nucleic Acids Res (1992) 1.69
Expression of a distinctive BCR-ABL oncogene in Ph1-positive acute lymphocytic leukemia (ALL). Science (1988) 1.59
A long-term dose-response study of mitomycin in glaucoma filtration surgery. Arch Ophthalmol (1997) 1.58
Cytogenetic and molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases. Proc Natl Acad Sci U S A (1993) 1.56
A chromosome 14 inversion in a T-cell lymphoma is caused by site-specific recombination between immunoglobulin and T-cell receptor loci. Nature (1986) 1.55
Ahmed glaucoma valve implant vs trabeculectomy in the surgical treatment of glaucoma: a randomized clinical trial. Am J Ophthalmol (2000) 1.54
Mutations in the KCNQ4 gene are responsible for autosomal dominant deafness in four DFNA2 families. Hum Mol Genet (1999) 1.54
A randomized double-blind trial of oral L-arginine for treatment of interstitial cystitis. J Urol (1999) 1.53
Prospective results of a standardized algorithm based on hemodynamic status for managing pediatric solid organ injury. J Am Coll Surg (2001) 1.50
Treatment of CNS relapse in children with acute lymphoblastic leukemia: A Pediatric Oncology Group study. J Clin Oncol (1993) 1.45
Detection of point mutations with a modified ligase chain reaction (Gap-LCR). Nucleic Acids Res (1995) 1.42
A new fused transcript in Philadelphia chromosome positive acute lymphocytic leukaemia. Nature (1987) 1.42
rUBF, an RNA polymerase I transcription factor from rats, produces DNase I footprints identical to those produced by xUBF, its homolog from frogs. Mol Cell Biol (1990) 1.41
The gene for enhancer binding proteins E12/E47 lies at the t(1;19) breakpoint in acute leukemias. Science (1989) 1.41
Bacterial infection induces nitric oxide synthase in human neutrophils. J Clin Invest (1997) 1.40
Obtaining an accepted Investigational New Drug application to operate an umbilical cord blood bank. Transfusion (1999) 1.39
Testicular temperatures measured by thermistor probe and contact thermography. Fertil Steril (1990) 1.39
Takayasu's arteritis identified by computerized tomography: revealing the submerged portion of the iceberg? Isr Med Assoc J (1999) 1.38
Quantitative trait locus for reading disability: correction. Science (1995) 1.37
Phonological processing skills and deficits in adult dyslexics. Child Dev (1990) 1.35
Isolation and characterization of cloned DNA: the delta and beta globin genes in homozygous beta + thalassemia. Blood (1981) 1.33
Hypoxia limits differentiation and up-regulates expression and activity of prostaglandin H synthase 2 in cultured trophoblast from term human placenta. Am J Obstet Gynecol (1999) 1.33
Evidence for linkage and association with reading disability on 6p21.3-22. Am J Hum Genet (2002) 1.31
Cytotoxic T lymphocytes specific for self tumor immunoglobulin express T cell receptor delta chain. J Exp Med (1989) 1.26
Analysis of DNA surrounding the breakpoints of chromosomal translocations involving the beta T cell receptor gene in human lymphoblastic neoplasms. Cell (1987) 1.26
Delineation of a minimal interval and identification of 9 candidates for a tumor suppressor gene in malignant myeloid disorders on 5q31. Blood (2000) 1.26
Apoptosis in human cultured trophoblasts is enhanced by hypoxia and diminished by epidermal growth factor. Am J Physiol Cell Physiol (2000) 1.25
A novel nuclear protein, 5qNCA (LOC51780) is a candidate for the myeloid leukemia tumor suppressor gene on chromosome 5 band q31. Oncogene (2001) 1.25
Common mechanism of chromosome inversion in B- and T-cell tumors: relevance to lymphoid development. Science (1986) 1.21
Hypoxia reduces expression and function of system A amino acid transporters in cultured term human trophoblasts. Am J Physiol Cell Physiol (2002) 1.20
Absence of cell surface LFA-1 as a mechanism of escape from immunosurveillance. Lancet (1987) 1.18
Polymerase chain reaction-based diagnosis of del (5q) in acute myeloid leukemia and myelodysplastic syndrome identifies a minimal deletion interval. Blood (1996) 1.17
Rb and p130 regulate RNA polymerase I transcription: Rb disrupts the interaction between UBF and SL-1. Oncogene (2000) 1.17
Evidence for major gene transmission of developmental dyslexia. JAMA (1991) 1.15
Intellect and behaviour in Duchenne muscular dystrophy. Dev Med Child Neurol (1981) 1.15
Early confirmation of stress fractures in joggers. JAMA (1980) 1.14
Loss of heterozygosity from the short arm of chromosome 8 is associated with invasive behavior in breast cancer. Genes Chromosomes Cancer (1996) 1.14
Translocation of the p53 gene in t(15;17) in acute promyelocytic leukaemia. Nature (1985) 1.14
Chromosomal translocation involving the beta T cell receptor gene in acute leukemia. J Exp Med (1988) 1.14
Cytogenetic studies of a patient with mosaicism of isochromosome 13q and a dicentric (Y;13) translocation showing differential centromeric activity. Clin Genet (1983) 1.14
Congenital anaemia after transplacental B19 parvovirus infection. Lancet (1994) 1.13
Early video-assisted thoracic surgery in the management of empyema. Pediatrics (1999) 1.12
Association of a chromosomal 3;21 translocation with the blast phase of chronic myelogenous leukemia. Blood (1987) 1.12
Purification and characterization of human T-lymphocyte-derived erythroid-potentiating activity. J Biol Chem (1984) 1.11
Cytogenetic and immunophenotypic analysis of cell lines established from patients with T cell leukemia/lymphoma. Blood (1986) 1.11
Consistent breakage between consensus recombinase heptamers of chromosome 9 DNA in a recurrent chromosomal translocation of human T cell leukemia. J Exp Med (1989) 1.11
Peroxisome proliferator-activated receptor-gamma modulates differentiation of human trophoblast in a ligand-specific manner. J Clin Endocrinol Metab (2000) 1.10
Novel mutation in the KCNQ4 gene in a large kindred with dominant progressive hearing loss. Hum Mutat (1999) 1.10
Pulmonary involvement with cytomegalovirus infections in children. Arch Dis Child (1977) 1.09
An autosomal recessive nonsyndromic form of sensorineural hearing loss maps to 3p-DFNB6. Genome Res (1995) 1.09
The ligase chain reaction in DNA-based diagnosis. Ann Biol Clin (Paris) (1993) 1.07
Coupling between p210bcr-abl and Shc and Grb2 adaptor proteins in hematopoietic cells permits growth factor receptor-independent link to ras activation pathway. J Exp Med (1994) 1.07
Overexpression of the MDM2 gene by childhood acute lymphoblastic leukemia cells expressing the wild-type p53 gene. Blood (1995) 1.07
In-vitro maturation of human oocytes from regularly menstruating women may be successful without follicle stimulating hormone priming. Hum Reprod (1999) 1.06
Is computed tomography a useful adjunct to the clinical examination for the diagnosis of pediatric gastrointestinal perforation from blunt abdominal trauma in children? J Trauma (1996) 1.06
Catheter sepsis in short-bowel syndrome. Arch Surg (1992) 1.06
Development of a microsatellite genetic map spanning 5q31-q33 and subsequent placement of the LGMD1A locus between D5S178 and IL9. Neuromuscul Disord (1995) 1.04
Evidence for a common molecular pathogenesis in colorectal, gastric, and pancreatic cancer. Genes Chromosomes Cancer (1991) 1.03
Characterization of the breakpoint of a t(14;14)(q11.2;q32) from the leukemic cells of a patient with T-cell acute lymphoblastic leukemia. Cancer Genet Cytogenet (1990) 1.03
Inducible nitric oxide synthase with transitional cell carcinoma of the bladder. J Urol (1999) 1.02
Role of intestinal mucus in transepithelial passage of bacteria across the intact ileum in vitro. Surgery (1994) 1.02
Quality improvement: the role and application of research methods. J Health Adm Educ (1989) 1.02
The Antioxidants in Prevention of Cataracts Study: effects of antioxidant supplements on cataract progression in South India. Br J Ophthalmol (2006) 1.02
Assignment of the GM-CSF, CSF-1, and FMS genes to human chromosome 5 provides evidence for linkage of a family of genes regulating hematopoiesis and for their involvement in the deletion (5q) in myeloid disorders. Cold Spring Harb Symp Quant Biol (1986) 1.02
Consanguineous nuclear families used to identify a new locus for recessive non-syndromic hearing loss on 14q. Hum Mol Genet (1995) 1.01
Clinical problems in hairy cell leukemia: diagnosis and management. Semin Oncol (1984) 1.01
Expression of BCL-2, BAX and BAK in the trophoblast layer of the term human placenta: a unique model of apoptosis within a syncytium. Placenta (2000) 1.00
Translocation and rearrangement of myeloperoxidase gene in acute promyelocytic leukemia. Science (1988) 1.00
The slipping rib syndrome in children. Paediatr Anaesth (2001) 0.99