Cellular localization of nerve growth factor synthesis by in situ hybridization.

PubWeight™: 1.28‹?› | Rank: Top 10%

🔗 View Article (PMC 553479)

Published in EMBO J on April 01, 1987

Authors

C E Bandtlow, R Heumann, M E Schwab, H Thoenen

Articles citing this

Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non-NMDA glutamate receptors. EMBO J (1990) 2.54

Contribution of interleukin-1 beta to the inflammation-induced increase in nerve growth factor levels and inflammatory hyperalgesia. Br J Pharmacol (1995) 2.12

Peripheral nerve regeneration and neurotrophic factors. J Anat (1999) 1.96

Enhanced synthesis of brain-derived neurotrophic factor in the lesioned peripheral nerve: different mechanisms are responsible for the regulation of BDNF and NGF mRNA. J Cell Biol (1992) 1.87

Differential regulation of mRNA encoding nerve growth factor and its receptor in rat sciatic nerve during development, degeneration, and regeneration: role of macrophages. Proc Natl Acad Sci U S A (1987) 1.70

Mitochondrial membrane potential in axons increases with local nerve growth factor or semaphorin signaling. J Neurosci (2008) 1.51

Establishment of neurovascular congruency in the mouse whisker system by an independent patterning mechanism. Neuron (2013) 1.47

Basement membrane and repair of injury to peripheral nerve: defining a potential role for macrophages, matrix metalloproteinases, and tissue inhibitor of metalloproteinases-1. J Exp Med (1996) 1.34

Heterophilic binding of L1 on unmyelinated sensory axons mediates Schwann cell adhesion and is required for axonal survival. J Cell Biol (1999) 1.32

Nerve growth factor and its low-affinity receptor promote Schwann cell migration. Proc Natl Acad Sci U S A (1994) 1.32

The role of the Schwann cell in trophic support and regeneration. J Neurol (1994) 1.30

PDGF A chain homodimers drive proliferation of bipotential (O-2A) glial progenitor cells in the developing rat optic nerve. EMBO J (1989) 1.23

Regional and cellular codistribution of interleukin 1 beta and nerve growth factor mRNA in the adult rat brain: possible relationship to the regulation of nerve growth factor synthesis. J Cell Biol (1990) 1.13

Expression of neurotrophins and their receptors in human bone marrow. Am J Pathol (1999) 1.08

Motor neurons contain agrin-like molecules. J Cell Biol (1988) 0.96

Inactivation of fibroblast growth factor receptor signaling in myelinating glial cells results in significant loss of adult spiral ganglion neurons accompanied by age-related hearing impairment. J Neurosci Res (2009) 0.92

Glial lineages and myelination in the central nervous system. J Anat (1997) 0.92

trans activation of nerve growth factor in transgenic mice containing the human T-cell lymphotropic virus type I tax gene. Mol Cell Biol (1991) 0.85

Neurotrophic factor changes in the rat thick skin following chronic constriction injury of the sciatic nerve. Mol Pain (2012) 0.84

Disruption of fibroblast growth factor receptor signaling in nonmyelinating Schwann cells causes sensory axonal neuropathy and impairment of thermal pain sensitivity. J Neurosci (2009) 0.83

Nerve growth factor depletion reduces collateral sprouting of cutaneous mechanoreceptive and tooth-pulp axons in ferrets. J Physiol (1994) 0.81

Expression of basic fibroblast growth factor, nerve growth factor, platelet-derived growth factor and transforming growth factor-beta in human brain abscess. Acta Neuropathol (1994) 0.80

Nerve growth factor promoter activity revealed in mice expressing enhanced green fluorescent protein. J Comp Neurol (2011) 0.80

NGF, brain and behavioral plasticity. Neural Plast (2012) 0.79

Emerging therapy for diabetic neuropathy: cell therapy targeting vessels and nerves. Endocr Metab Immune Disord Drug Targets (2012) 0.79

The effect of NGF depletion on the neurotropic influence exerted by the distal stump following nerve transection. J Anat (1995) 0.76

Relationship between the sympathetic nervous system and vascular smooth muscle: a morphometric study of adult and juvenile spontaneously hypertensive rat/Wistar-Kyoto rat caudal artery. Heart Vessels (1990) 0.75

Synthesis of nerve growth factor mRNA in cultures of developing mouse whisker pad, a peripheral target tissue of sensory trigeminal neurons. J Cell Biol (1993) 0.75

Articles cited by this

Kinetics of renaturation of DNA. J Mol Biol (1968) 25.41

Nerve growth factor. Physiol Rev (1968) 9.12

Physiology of nerve growth factor. Physiol Rev (1980) 4.58

The kinetics of antibody binding to membrane antigens in solution and at the cell surface. Biochem J (1980) 4.37

Immunofluorescent staining of keratin fibers in cultured cells. Cell (1978) 4.25

Primary cultures of dissociated sympathetic neurons. I. Establishment of long-term growth in culture and studies of differentiated properties. J Cell Biol (1973) 3.87

The use of heparin as a simple cost-effective means of controlling background in nucleic acid hybridization procedures. Nucleic Acids Res (1984) 3.73

Monoclonal antibodies (O1 to O4) to oligodendrocyte cell surfaces: an immunocytological study in the central nervous system. Dev Biol (1981) 3.35

Quantitative analysis of in situ hybridization methods for the detection of actin gene expression. Nucleic Acids Res (1985) 3.00

The nerve growth factor: biochemistry, synthesis, and mechanism of action. Annu Rev Neurosci (1980) 2.61

Isolation and nucleotide sequence of a cDNA encoding the precursor of mouse nerve growth factor. Nature (1983) 2.41

Nerve growth factor in sympathetic ganglia and corresponding target organs of the rat: correlation with density of sympathetic innervation. Proc Natl Acad Sci U S A (1983) 2.17

Expression of the beta-nerve growth factor gene correlates with the density of sympathetic innervation in effector organs. Proc Natl Acad Sci U S A (1984) 2.16

Monoclonal antibodies to desmin, the muscle-specific intermediate filament protein. EMBO J (1983) 2.07

Induction of nerve growth factor receptor in Schwann cells after axotomy. Proc Natl Acad Sci U S A (1986) 2.06

Levels of nerve growth factor and its mRNA in the central nervous system of the rat correlate with cholinergic innervation. EMBO J (1985) 1.93

Dissociated neurons regenerate into sciatic but not optic nerve explants in culture irrespective of neurotrophic factors. J Neurosci (1985) 1.82

NGF-mediated increase of choline acetyltransferase (ChAT) in the neonatal rat forebrain: evidence for a physiological role of NGF in the brain? Brain Res (1983) 1.77

Relationship between levels of nerve growth factor (NGF) and its messenger RNA in sympathetic ganglia and peripheral target tissues. EMBO J (1984) 1.71

Relation of target encounter and neuronal death to nerve growth factor responsiveness in the developing mouse trigeminal ganglion. J Comp Neurol (1984) 1.42

Choline acetyltransferase activity in striatum of neonatal rats increased by nerve growth factor. Science (1985) 1.41

Nerve growth factors in the rat iris. Nature (1980) 1.39

Immunohistochemical localization of endogenous nerve growth factor. Nature (1984) 1.29

Synthesis and effects of basement membrane components in cultured rat Schwann cells. Dev Biol (1984) 1.27

Comparison between the time course of changes in nerve growth factor protein levels and those of its messenger RNA in the cultured rat iris. J Biol Chem (1986) 1.18

beta-Nerve growth factor (beta NGF) receptors on glial cells. Cell-cell interaction between neurones and Schwann cells in cultures of chick sensory ganglia. EMBO J (1983) 1.17

In situ hybridization of immunoglobulin-specific RNA in single cells of the B lymphocyte lineage with radiolabelled DNA probes. EMBO J (1986) 1.15

Molecular cloning of bovine and chick nerve growth factor (NGF): delineation of conserved and unconserved domains and their relationship to the biological activity and antigenicity of NGF. EMBO J (1986) 1.13

Regulation of nerve growth factor synthesis and release in organ cultures of rat iris. J Cell Biol (1984) 1.08

Treatment with 6-hydroxydopamine and colchicine decreases nerve growth factor levels in sympathetic ganglia and increases them in the corresponding target tissues. J Neurosci (1985) 1.07

Presence and disappearance of nerve growth factor receptors on sensory neurons in culture. Dev Biol (1982) 1.00

Studies on the regulation of beta-nerve growth factor gene expression in the rat iris: the level of mRNA-encoding nerve growth factor is increased in irises placed in explant cultures in vitro, but not in irises deprived of sensory or sympathetic innervation in vivo. J Cell Biol (1986) 0.93

Nerve growth factor immunohistochemistry and biological activity in the rat iris. J Neurocytol (1986) 0.88

In situ hybridization--visualization and quantitation of genetic expression in mammalian brain. Peptides (1985) 0.79

Ultrastructural and histochemical studies of the rat iris: identified neuronal inputs and supportive glia. J Neurocytol (1984) 0.79

Articles by these authors

Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor. Proc Natl Acad Sci U S A (1995) 5.25

Nogo-A is a myelin-associated neurite outgrowth inhibitor and an antigen for monoclonal antibody IN-1. Nature (2000) 5.22

Chemical sympathectomy by selective destruction of adrenergic nerve endings with 6-Hydroxydopamine. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol (1968) 4.85

Physiology of nerve growth factor. Physiol Rev (1980) 4.58

Molecular cloning and expression of brain-derived neurotrophic factor. Nature (1989) 3.90

Erythropoietin prevents neuronal apoptosis after cerebral ischemia and metabolic stress. Proc Natl Acad Sci U S A (2001) 3.80

Purification of a new neurotrophic factor from mammalian brain. EMBO J (1982) 3.68

Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy. Nature (1992) 3.39

The heparin-binding domain of laminin is responsible for its effects on neurite outgrowth and neuronal survival. EMBO J (1984) 3.39

Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors. Nature (1990) 3.22

Neurite growth inhibitors restrict plasticity and functional recovery following corticospinal tract lesions. Nat Neurosci (1998) 3.15

Plasticity of motor systems after incomplete spinal cord injury. Nat Rev Neurosci (2001) 3.11

Neurotrophin-evoked rapid excitation through TrkB receptors. Nature (1999) 3.11

Recovery from spinal cord injury mediated by antibodies to neurite growth inhibitors. Nature (1995) 2.93

Antibody against myelin-associated inhibitor of neurite growth neutralizes nonpermissive substrate properties of CNS white matter. Neuron (1988) 2.69

The retrograde axonal transport of nerve growth factor. Brain Res (1974) 2.60

Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion. Nature (1994) 2.57

Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non-NMDA glutamate receptors. EMBO J (1990) 2.54

Interleukin-1 regulates synthesis of nerve growth factor in non-neuronal cells of rat sciatic nerve. Nature (1988) 2.47

Changes of nerve growth factor synthesis in nonneuronal cells in response to sciatic nerve transection. J Cell Biol (1987) 2.40

Synaptic secretion of BDNF after high-frequency stimulation of glutamatergic synapses. EMBO J (2001) 2.38

Increase in tyrosine hydroxylase activity after reserpine administration. J Pharmacol Exp Ther (1969) 2.32

Disruption of the CNTF gene results in motor neuron degeneration. Nature (1993) 2.22

On the cellular source and function of interleukin 6 produced in the central nervous system in viral diseases. Eur J Immunol (1989) 2.20

Light regulates expression of brain-derived neurotrophic factor mRNA in rat visual cortex. Proc Natl Acad Sci U S A (1992) 2.19

BDNF and NT-4/5 enhance glutamatergic synaptic transmission in cultured hippocampal neurones. Neuroreport (1994) 2.19

Nerve growth factor in sympathetic ganglia and corresponding target organs of the rat: correlation with density of sympathetic innervation. Proc Natl Acad Sci U S A (1983) 2.17

Virus-mediated gene transfer into hippocampal CA1 region restores long-term potentiation in brain-derived neurotrophic factor mutant mice. Proc Natl Acad Sci U S A (1996) 2.10

Some pharmacological actions of the beta-adrenolytic agent Ro 3-3528 (6,7-dimethyl-alpha-[(isopropylamino) methyl]-2-benzofuranmethanol Hydrochloride). Angiologica (1967) 2.10

A role for BDNF in mechanosensation. Nat Neurosci (1998) 2.08

Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy. Nature (1990) 2.06

An electron microscopic study of selective, acute degeneration of sympathetic nerve terminals after administration of 6-hydroxydopamine. Experientia (1968) 1.98

Ataxia and altered dendritic calcium signaling in mice carrying a targeted null mutation of the calbindin D28k gene. Proc Natl Acad Sci U S A (1997) 1.96

Selective induction by nerve growth factor of tyrosine hydroxylase and dopamine- -hydroxylase in the rat superior cervical ganglia. Proc Natl Acad Sci U S A (1971) 1.96

Levels of nerve growth factor and its mRNA in the central nervous system of the rat correlate with cholinergic innervation. EMBO J (1985) 1.93

Relation between the rate of stimulation and the quantity of noradrenaline liberated from sympathetic nerve endings in the isolated perfused spleen of the cat. J Physiol (1965) 1.92

Two membrane protein fractions from rat central myelin with inhibitory properties for neurite growth and fibroblast spreading. J Cell Biol (1988) 1.89

Enhanced synthesis of brain-derived neurotrophic factor in the lesioned peripheral nerve: different mechanisms are responsible for the regulation of BDNF and NGF mRNA. J Cell Biol (1992) 1.87

Dual site of action of phenoxybenzamine in the cat's spleen; blockade of alpha-adrenergic receptors and inhibition of re-uptake of neurally released norepinephrine. Experientia (1964) 1.83

Dissociated neurons regenerate into sciatic but not optic nerve explants in culture irrespective of neurotrophic factors. J Neurosci (1985) 1.82

Providing the clinical basis for new interventional therapies: refined diagnosis and assessment of recovery after spinal cord injury. Spinal Cord (2004) 1.82

Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor. Nature (1990) 1.80

Interplay between glutamate and gamma-aminobutyric acid transmitter systems in the physiological regulation of brain-derived neurotrophic factor and nerve growth factor synthesis in hippocampal neurons. Proc Natl Acad Sci U S A (1991) 1.79

Anatomical correlates of locomotor recovery following dorsal and ventral lesions of the rat spinal cord. Exp Neurol (2002) 1.77

NGF-mediated increase of choline acetyltransferase (ChAT) in the neonatal rat forebrain: evidence for a physiological role of NGF in the brain? Brain Res (1983) 1.77

Timing and site of nerve growth factor synthesis in developing skin in relation to innervation and expression of the receptor. Nature (1987) 1.76

Characterization of nerve growth factor (NGF) release from hippocampal neurons: evidence for a constitutive and an unconventional sodium-dependent regulated pathway. Eur J Neurosci (1995) 1.72

Increased tyrosine hydroxylase activity after drug-induced alteration of sympathetic transmission. Nature (1969) 1.72

Relationship between levels of nerve growth factor (NGF) and its messenger RNA in sympathetic ganglia and peripheral target tissues. EMBO J (1984) 1.71

Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section. Nature (1993) 1.71

The induction of LTP increases BDNF and NGF mRNA but decreases NT-3 mRNA in the dentate gyrus. Neuroreport (1993) 1.70

Differential regulation of mRNA encoding nerve growth factor and its receptor in rat sciatic nerve during development, degeneration, and regeneration: role of macrophages. Proc Natl Acad Sci U S A (1987) 1.70

Sensory neurons in culture: changing requirements for survival factors during embryonic development. Proc Natl Acad Sci U S A (1980) 1.69

Acute inflammatory responses to mechanical lesions in the CNS: differences between brain and spinal cord. Eur J Neurosci (1999) 1.68

Central adrenergic neurones and the initiation and development of experimental hypertension. Experientia (1972) 1.67

Trans-synaptic induction of adrenal tyrosine hydroxylase. J Pharmacol Exp Ther (1969) 1.67

Secondary cell death and the inflammatory reaction after dorsal hemisection of the rat spinal cord. Eur J Neurosci (1994) 1.64

Transforming growth factor-beta 1 in the rat brain: increase after injury and inhibition of astrocyte proliferation. J Cell Biol (1992) 1.64

Brain-derived neurotrophic factor supports the survival of cultured rat retinal ganglion cells. J Neurosci (1986) 1.64

Electronmicroscopic localization of 5-hydroxydopamine (3,4,5-trihydroxy-phenyl-ethylamine), a new 'false' sympathetic transmitter. Experientia (1967) 1.61

Efficient testing of motor function in spinal cord injured rats. Brain Res (2000) 1.61

Nerve growth factor in mouse and rat serum: correlation between bioassay and radioimmunoassay determinations. Proc Natl Acad Sci U S A (1978) 1.59

Positive feedback between acetylcholine and the neurotrophins nerve growth factor and brain-derived neurotrophic factor in the rat hippocampus. Eur J Neurosci (1994) 1.57

Placode and neural crest-derived sensory neurons are responsive at early developmental stages to brain-derived neurotrophic factor. Dev Biol (1985) 1.57

Neurotrophin release by neurotrophins: implications for activity-dependent neuronal plasticity. Proc Natl Acad Sci U S A (1997) 1.55

Potentiation by tetraethylammonium of the response of the cat spleen to postganglionic sympathetic nerve stimulation. J Pharmacol Exp Ther (1967) 1.54

Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: comparison with other neurotrophic factors and cytokines. J Neurosci (1990) 1.53

Functional recovery and enhanced corticofugal plasticity after unilateral pyramidal tract lesion and blockade of myelin-associated neurite growth inhibitors in adult rats. J Neurosci (1998) 1.53

BDNF-GFP containing secretory granules are localized in the vicinity of synaptic junctions of cultured cortical neurons. J Cell Sci (1998) 1.52

Specificity of the retrograde axonal transport of nerve growth factor. Brain Res (1974) 1.52

Cells of origin, course, and termination patterns of the ventral, uncrossed component of the mature rat corticospinal tract. J Comp Neurol (1997) 1.51

Specific retrograde transport of nerve growth factor (NGF) from neocortex to nucleus basalis in the rat. Brain Res (1984) 1.51

Synthesis and localization of ciliary neurotrophic factor in the sciatic nerve of the adult rat after lesion and during regeneration. J Cell Biol (1992) 1.51

Nerve growth factor-induced fiber outgrowth from isolated rat adrenal chromaffin cells: impairment by glucocorticoids. Proc Natl Acad Sci U S A (1978) 1.50

Ciliary neurotrophic factor: pharmacokinetics and acute-phase response in rat. Ann Neurol (1994) 1.49

Purification of nerve growth factor antibodies by affinity chromatography. J Neurochem (1976) 1.49

Validation of the weight-drop contusion model in rats: a comparative study of human spinal cord injury. J Neurotrauma (2000) 1.47

ras p21 protein promotes survival and fiber outgrowth of cultured embryonic neurons. Neuron (1989) 1.46

Chemical sympathectomy of the cat with 6-hydroxydopamine. J Pharmacol Exp Ther (1969) 1.46

Locomotor recovery in spinal cord-injured rats treated with an antibody neutralizing the myelin-associated neurite growth inhibitor Nogo-A. J Neurosci (2001) 1.46

Regeneration of lesioned corticospinal tract fibers in the adult rat induced by a recombinant, humanized IN-1 antibody fragment. J Neurosci (2000) 1.45

Membrane-type 1 matrix metalloprotease (MT1-MMP) enables invasive migration of glioma cells in central nervous system white matter. J Cell Biol (1999) 1.45

Comparative studies on the effect of the nerve growth factor on sympathetic ganglia and adrenal medulla in newborn rats. Brain Res (1972) 1.44

Inhibitors of neurite growth. Annu Rev Neurosci (1993) 1.43

Disinhibition of neurite growth to repair the injured adult CNS: focusing on Nogo. Cell Mol Life Sci (2008) 1.41

Comparison between the retrograde axonal transport of nerve growth factor and tetanus toxin in motor, sensory and adrenergic neurons. Brain Res (1975) 1.40

Activity-dependent and hormonal regulation of neurotrophin mRNA levels in the brain--implications for neuronal plasticity. J Neurobiol (1994) 1.40

Cervical sprouting of corticospinal fibers after thoracic spinal cord injury accompanies shifts in evoked motor responses. Curr Biol (2001) 1.39

Regulation of brain-derived neurotrophic factor and nerve growth factor mRNA in primary cultures of hippocampal neurons and astrocytes. J Neurosci (1992) 1.37

Relationship between NGF-mediated volume increase and "priming effect" in fast and slow reacting clones of PC12 pheochromocytoma cells. Role of cAMP. Exp Cell Res (1983) 1.36

Specific subtypes of cutaneous mechanoreceptors require neurotrophin-3 following peripheral target innervation. Neuron (1996) 1.36