Obesity-linked phosphorylation of SIRT1 by CK2 inhibits its nuclear localization and promotes fatty liver.

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Published in Mol Cell Biol on May 22, 2017

Authors

Sung E Choi1,2, Sanghoon Kwon1, Sunmi Seok1, Zhen Xiao3, Kwan-Woo Lee4, Yup Kang2, Xiaoling Li5, Kosaku Shinoda6, Shingo Kajimura6, Byron Kemper1, Jongsook Kim Kemper7

Author Affiliations

1: Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
2: Department of Physiology, Ajou University School of Medicine, Suwon, Kyunggi-do, Republic of Korea.
3: Laboratory of Proteomics and Analytical Technologies, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
4: Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, Kyunggi-do, Republic of Korea.
5: Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA.
6: Laboratory UCSF Diabetes Center and Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, California, USA.
7: Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA jongsook@illinois.edu.

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