Published in Mol Cell Biol on December 01, 1988
A versatile viral system for expression and depletion of proteins in mammalian cells. PLoS One (2009) 3.83
Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1. J Cell Biol (1998) 3.11
An amino acid sequence motif sufficient for subnuclear localization of an arginine/serine-rich splicing factor. Proc Natl Acad Sci U S A (1995) 1.92
Cooperation of proto-signals for nuclear accumulation of estrogen and progesterone receptors. EMBO J (1992) 1.88
Hydrogen peroxide triggers nuclear export of telomerase reverse transcriptase via Src kinase family-dependent phosphorylation of tyrosine 707. Mol Cell Biol (2003) 1.57
Novel role of antioxidant-1 (Atox1) as a copper-dependent transcription factor involved in cell proliferation. J Biol Chem (2008) 1.55
Mechanical properties of the cell nucleus and the effect of emerin deficiency. Biophys J (2006) 1.40
Expression and targeting of intracellular antibodies in mammalian cells. EMBO J (1990) 1.38
Nuclear localization of the adenovirus DNA-binding protein: requirement for two signals and complementation during viral infection. Mol Cell Biol (1989) 1.23
Nuclear transport of U1 snRNP in somatic cells: differences in signal requirement compared with Xenopus laevis oocytes. J Cell Biol (1994) 1.20
A hydrophobic protein sequence can override a nuclear localization signal independently of protein context. Mol Cell Biol (1991) 0.88
Functional interaction of nuclear transport-defective simian virus 40 large T antigen with chromatin and nuclear matrix. J Virol (1990) 0.83
Analysis of the v-myb structural components important for transactivation of gene expression. Nucleic Acids Res (1991) 0.83
MagFRET: the first genetically encoded fluorescent Mg2+ sensor. PLoS One (2013) 0.79
A versatile, bar-coded nuclear marker/reporter for live cell fluorescent and multiplexed high content imaging. PLoS One (2013) 0.79
Zinc finger transcription factor ecotropic viral integration site 1 is induced by all-trans retinoic acid (ATRA) and acts as a dual modulator of the ATRA response. FEBS J (2009) 0.78
Small Molecule Inhibitors Targeting Tec Kinase Block Unconventional Secretion of Fibroblast Growth Factor 2. J Biol Chem (2016) 0.76
All for one but not one for all: Excitatory synaptic scaling and intrinsic excitability are coregulated by CaMKIV, while inhibitory synaptic scaling is under independent control. J Neurosci (2017) 0.75
SV40-transformed simian cells support the replication of early SV40 mutants. Cell (1981) 34.67
Prediction of protein antigenic determinants from amino acid sequences. Proc Natl Acad Sci U S A (1981) 32.98
A short amino acid sequence able to specify nuclear location. Cell (1984) 21.17
Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature (1983) 19.76
A new dominant hybrid selective marker for higher eukaryotic cells. J Mol Biol (1981) 9.51
Targeting of E. coli beta-galactosidase to the nucleus in yeast. Cell (1984) 7.34
Nuclear protein migration involves two steps: rapid binding at the nuclear envelope followed by slower translocation through nuclear pores. Cell (1988) 7.23
Nuclear import can be separated into distinct steps in vitro: nuclear pore binding and translocation. Cell (1988) 6.60
Movement of a karyophilic protein through the nuclear pores of oocytes. J Cell Biol (1984) 6.51
A polypeptide domain that specifies migration of nucleoplasmin into the nucleus. Cell (1982) 6.39
Construction and characterization of an SV40 mutant defective in nuclear transport of T antigen. Cell (1984) 5.81
Nuclear location signals in polyoma virus large-T. Cell (1986) 5.74
Definition of regions in human c-myc that are involved in transformation and nuclear localization. Mol Cell Biol (1987) 5.67
Synthetic peptides as nuclear localization signals. Nature (1986) 5.35
Viral oncogenes. Cell (1985) 5.20
Amino terminus of the yeast GAL4 gene product is sufficient for nuclear localization. Proc Natl Acad Sci U S A (1984) 4.90
Induction of nuclear transport with a synthetic peptide homologous to the SV40 T antigen transport signal. Cell (1986) 4.56
Expression of the large T protein of polyoma virus promotes the establishment in culture of "normal" rodent fibroblast cell lines. Proc Natl Acad Sci U S A (1983) 3.65
The action of oncogenes in the cytoplasm and nucleus. Science (1985) 3.62
Identification of the sequence responsible for the nuclear accumulation of the influenza virus nucleoprotein in Xenopus oocytes. Cell (1985) 3.36
The nuclear migration signal of Xenopus laevis nucleoplasmin. EMBO J (1987) 3.36
Amino acid sequences that determine the nuclear localization of yeast histone 2B. Mol Cell Biol (1987) 3.31
Simian virus 40 large T antigen is phosphorylated at multiple sites clustered in two separate regions. J Virol (1982) 3.18
The effect of protein context on nuclear location signal function. Cell (1987) 2.83
A domain of SV40 capsid polypeptide VP1 that specifies migration into the cell nucleus. EMBO J (1986) 2.51
Identification of a nuclear localization signal of a yeast ribosomal protein. Proc Natl Acad Sci U S A (1985) 2.39
Pentapeptide nuclear localization signal in adenovirus E1a. Mol Cell Biol (1987) 2.30
High-frequency transfection of CHO cells using polybrene. Somat Cell Mol Genet (1986) 2.29
SV40 small t antigen enhances the transformation activity of limiting concentrations of SV40 large T antigen. Cell (1987) 2.13
In vitro establishment is not a sufficient prerequisite for transformation by activated ras oncogenes. Cell (1986) 2.13
Construction and functional characterization of polyomavirus genomes that separately encode the three early proteins. J Virol (1984) 2.02
Simian virus 40 origin DNA-binding domain on large T antigen. J Virol (1986) 1.80
Extensive mutagenesis of the nuclear location signal of simian virus 40 large-T antigen. Mol Cell Biol (1986) 1.65
Studies on the origin-specific DNA-binding domain of simian virus 40 large T antigen. J Virol (1987) 1.56
Identification of a signal for nuclear targeting in platelet-derived-growth-factor-related molecules. Mol Cell Biol (1987) 1.38
Activated Ha-ras can cooperate with defective simian virus 40 in the transformation of nonestablished rat embryo fibroblasts. J Virol (1987) 1.36
The intranuclear location of simian virus 40 polypeptides VP2 and VP3 depends on a specific amino acid sequence. J Virol (1987) 1.29
Signal-dependent translocation of simian virus 40 large-T antigen into rat liver nuclei in a cell-free system. Mol Cell Biol (1987) 1.26
The carboxyl 35 amino acids of SV40 Vp3 are essential for its nuclear accumulation. Virology (1987) 1.26
A second domain of simian virus 40 T antigen in which mutations can alter the cellular localization of the antigen. Mol Cell Biol (1986) 1.25
Relationship between simian virus 40 large tumor antigen expression and tumor formation in transgenic mice. J Virol (1987) 1.24
Construction and characterization of viable deletion mutants of simian virus 40 lacking sequences near the 3' end of the early region. J Virol (1982) 1.23
Kinetics of nuclear transport and oligomerization of simian virus 40 large T antigen. Virology (1986) 1.22
Deletion of 43 amino acids in the NH2-terminal half of the large tumor antigen of simian virus 40 results in a non-karyophilic protein capable of transforming established cells. Proc Natl Acad Sci U S A (1985) 1.15
A mutant SV40 large T antigen interferes with nuclear localization of a heterologous protein. Cell (1988) 0.96
trans-activation of cellular and viral promoters by a transforming nonkaryophilic simian virus 40 large T antigen. J Virol (1987) 0.95
SV40 large T-antigen: dual oncogene. Cancer Surv (1986) 0.94
Biochemical properties of a transforming nonkaryophilic T antigen of SV40. Virology (1986) 0.90
Ability of a T-antigen transport-defective mutant of simian virus 40 to immortalize primary cells and to complement polyomavirus middle T in tumorigenesis. J Virol (1986) 0.88
Tumorigenesis in transgenic mice by a nuclear transport-defective SV40 large T-antigen gene. Virology (1987) 0.85
A nonkaryophilic T antigen of SV40 can either immortalize or transform rodent cells, and cooperates better with cytoplasmic than with nuclear oncoproteins. Oncogene Res (1987) 0.79
Dimers and complexes with p53 are the prevalent oligomeric forms of a transforming nonkaryophilic T antigen of simian virus 40. J Virol (1987) 0.77
Properties of simian virus 40 mutants lacking the Asp4-Glu-Asp stretch at the carboxyl-terminus of large T antigen. Virology (1987) 0.76
Localization and kinetics of formation of nuclear heterodisperse RNA, cytoplasmic heterodisperse RNA and polyribosome-associated messenger RNA in HeLa cells. J Mol Biol (1968) 6.19
Selective inhibition of the synthesis of mitochondria-associated RNA by ethidium bromide. J Mol Biol (1969) 3.91
Activated Ha-ras can cooperate with defective simian virus 40 in the transformation of nonestablished rat embryo fibroblasts. J Virol (1987) 1.36
Late modifications of simian virus 40 chromatin during the lytic cycle occur in an immature form of virion. J Virol (1980) 1.35
The fractionation of nuclei and the integrity of purified nucleoli in HeLa cells. Biochim Biophys Acta (1968) 1.18
Deletion of 43 amino acids in the NH2-terminal half of the large tumor antigen of simian virus 40 results in a non-karyophilic protein capable of transforming established cells. Proc Natl Acad Sci U S A (1985) 1.15
The cytoplasmic RNA of HeLa cells: new discrete species associated with mitochondria. Proc Natl Acad Sci U S A (1969) 1.10
Role of ribosomal subunits in protein synthesis in mammalian cells. Proc Natl Acad Sci U S A (1968) 1.09
The RNA metabolism of nucleoli and mitochondria in mammalian cells. Cold Spring Harb Symp Quant Biol (1969) 1.07
The role of ribosomal subunits in mammalian cells. Cold Spring Harb Symp Quant Biol (1969) 1.05
Histone acetylation in CV-1 cells infected with simian virus 40. Virology (1979) 1.01
Effect of sodium fluoride on protein synthesis in HeLa cells: inhibition of ribosome dissociation. J Mol Biol (1970) 0.96
Cold-sensitive growth of simian virus 40 in semipermissive variants of CV1 cells. J Virol (1982) 0.95
trans-activation of cellular and viral promoters by a transforming nonkaryophilic simian virus 40 large T antigen. J Virol (1987) 0.95
Ribonucleoprotein particles involved in HeLa mitochondrial protein synthesis. Nat New Biol (1971) 0.90
Biochemical properties of a transforming nonkaryophilic T antigen of SV40. Virology (1986) 0.90
Regions of SV40 large T antigen necessary for oligomerization and complex formation with the cellular oncoprotein p53. FEBS Lett (1986) 0.88
Induction of mitochondrial DNA synthesis by polyoma virus. Nature (1971) 0.88
Kinetics of DNA and histone messenger RNA synthesis in CV-1 monkey kidney cells infected with simian virus 40. J Mol Biol (1976) 0.85
High mobility group proteins 1 and 2 are present in simian virus 40 provirions, but not in virions. Nucleic Acids Res (1981) 0.84
Limits of transforming competence of SV40 nuclear and cytoplasmic large T mutants with altered Rb binding sequences. Oncogene (1993) 0.83
Purified cytoplasmic DNA from HeLa cells: resistance to inhibition by hydroxyurea. Biochem Biophys Res Commun (1969) 0.82
Multiple effects of rifamycin derivatives on animal-cell metabolism of macromolecules. Eur J Biochem (1973) 0.82
Disaggregation of brain polysomes induced by electroconvulsive treatment. J Neurochem (1968) 0.81
Different histone families in intracellular SV40 nucleoprotein complexes with respect to the acetylation turnover. Virology (1982) 0.81
Pattern of RNA synthesis in rabbit brain. Biochim Biophys Acta (1967) 0.81
Tetrazolium reductase activity of the enzymatic systems of oxidation of reduced nicotinamide nucleotides in mammalian brain. Biochim Biophys Acta (1966) 0.81
A nonkaryophilic T antigen of SV40 can either immortalize or transform rodent cells, and cooperates better with cytoplasmic than with nuclear oncoproteins. Oncogene Res (1987) 0.79
Murine cell complementation of a cold-sensitive defect for simian virus 40 replication in simian cells. Mol Cell Biol (1982) 0.78
Dimers and complexes with p53 are the prevalent oligomeric forms of a transforming nonkaryophilic T antigen of simian virus 40. J Virol (1987) 0.77
Molecular cloning and restriction mapping of a simian virus 40 deletion mutant derived from simian transformants expressing a non-karyophilic T antigen. FEBS Lett (1984) 0.77
Insensitivity of mitochondrial RNA synthesis to mengovirus infection in CHO cells. Nature (1969) 0.75
[Tetrazolio-reductase activity of the cerebral systems of oxidation of the pyridine coenzymes]. Boll Soc Ital Biol Sper (1964) 0.75
MyoD activity upregulates E2F1 and enhances transcription from the cyclin E promoter in differentiating myoblasts lacking a functional retinoblastoma protein. Exp Cell Res (2001) 0.75
Independent regulation of the nuclear and mitochondrial DNA synthesis induced by either Simian virus 40 or serum in mouse fibroblast 3T3 cells. Eur J Biochem (1975) 0.75