Published in Mol Cell Biol on June 01, 1986
Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor. EMBO J (1987) 5.76
Definition of regions in human c-myc that are involved in transformation and nuclear localization. Mol Cell Biol (1987) 5.67
v-rel oncoproteins in the nucleus and in the cytoplasm transform chicken spleen cells. J Virol (1988) 2.08
Nucleocytoplasmic traffic disorder induced by cardioviruses. J Virol (2006) 1.59
Transcriptional interference between the EBV transcription factors EB1 and R: both DNA-binding and activation domains of EB1 are required. Nucleic Acids Res (1991) 1.53
Nuclear localization of the adenovirus DNA-binding protein: requirement for two signals and complementation during viral infection. Mol Cell Biol (1989) 1.23
Mutagenesis of adeno-associated virus type 2 capsid protein VP1 uncovers new roles for basic amino acids in trafficking and cell-specific transduction. J Virol (2010) 1.21
Cell-dependent efficiency of reiterated nuclear signals in a mutant simian virus 40 oncoprotein targeted to the nucleus. Mol Cell Biol (1988) 1.15
Temperature-sensitive mutants identify crucial structural regions of simian virus 40 large T antigen. J Virol (1989) 1.09
Application of an immunoprecipitation procedure to the study of SV40 tumor antigen interaction with mouse genomic DNA sequences. Nucleic Acids Res (1987) 1.05
Development of quantitative and high-throughput assays of polyomavirus and papillomavirus DNA replication. Virology (2010) 1.03
Cellular mutation mediates T-antigen-positive revertant cells resistant to simian virus 40 transformation but not to retransformation by polyomavirus and adenovirus type 2. J Virol (1987) 0.99
trans-activation of cellular and viral promoters by a transforming nonkaryophilic simian virus 40 large T antigen. J Virol (1987) 0.95
A karyophilic signal sequence in adenovirus type 5 E1A is functional in Xenopus oocytes but not in somatic cells. J Virol (1989) 0.87
Differential interaction of temperature-sensitive simian virus 40 T antigens with tumor suppressors pRb and p53. J Virol (1996) 0.82
Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol (1975) 503.08
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci U S A (1979) 365.71
Selective extraction of polyoma DNA from infected mouse cell cultures. J Mol Biol (1967) 106.91
A short amino acid sequence able to specify nuclear location. Cell (1984) 21.17
Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells. Cell (1977) 18.95
Monoclonal antibodies specific for simian virus 40 tumor antigens. J Virol (1981) 15.59
Inhibition of SV40 replication in simian cells by specific pBR322 DNA sequences. Nature (1981) 13.89
Sequence requirements for nuclear location of simian virus 40 large-T antigen. Nature (1984) 10.52
High efficiency polyoma DNA transfection of chloroquine treated cells. Nucleic Acids Res (1983) 9.94
Construction and analysis of viable deletion mutants of simian virus 40. J Virol (1976) 9.11
Monoclonal antibodies against simian virus 40 T antigens: evidence for distinct sublcasses of large T antigen and for similarities among nonviral T antigens. J Virol (1980) 7.51
Targeting of E. coli beta-galactosidase to the nucleus in yeast. Cell (1984) 7.34
A polypeptide domain that specifies migration of nucleoplasmin into the nucleus. Cell (1982) 6.39
A restriction map of the bacteriophage T4 genome. Mol Gen Genet (1980) 6.37
Defective simian virus 40 genomes: isolation and growth of individual clones. Virology (1974) 6.30
Construction and characterization of an SV40 mutant defective in nuclear transport of T antigen. Cell (1984) 5.81
Nuclear location signals in polyoma virus large-T. Cell (1986) 5.74
Binding of a simian virus 40 T antigen-related protein to DNA. J Mol Biol (1981) 4.76
Mutational analysis of simian virus 40 T antigen: isolation and characterization of mutants with deletions in the T-antigen gene. Mol Cell Biol (1983) 3.67
Identification of the sequence responsible for the nuclear accumulation of the influenza virus nucleoprotein in Xenopus oocytes. Cell (1985) 3.36
Intracellular migration of nuclear proteins in Xenopus oocytes. Nature (1978) 2.91
Subcellular Localization of simian virus 40 large tumor antigen. J Virol (1979) 2.03
Genetic and biochemical analysis of transformation-competent, replication-defective simian virus 40 large T antigen mutants. J Virol (1985) 1.92
Deletion loop mutagenesis: a novel method for the construction of point mutations using deletion mutants. Nucleic Acids Res (1982) 1.90
A small subclass of SV40 T antigen binds to the viral origin of replication. Cell (1982) 1.86
Local mutagenesis within deletion loops of DNA heteroduplexes. Proc Natl Acad Sci U S A (1982) 1.81
DNA-binding properties of simian virus 40 T-antigen mutants defective in viral DNA replication. Mol Cell Biol (1983) 1.76
Simian virus 40 mutant T antigens with relaxed specificity for the nucleotide sequence at the viral DNA origin of replication. J Virol (1984) 1.65
Simian virus 40 T-antigen-related cell surface antigen: serological demonstration on simian virus 40-transformed monolayer cells in situ. J Virol (1980) 1.36
Differential ability of a T-antigen transport-defective mutant of simian virus 40 to transform primary and established rodent cells. Mol Cell Biol (1985) 1.30
Intracellular transport of SV40 large tumor antigen: a mutation which abolishes migration to the nucleus does not prevent association with the cell surface. Virology (1982) 1.17
Accumulation of the isolated carboxy-terminal domain of histone H1 in the Xenopus oocyte nucleus. EMBO J (1984) 1.17
An adenovirus type 5 early gene function regulates expression of other early viral genes. Proc Natl Acad Sci U S A (1979) 13.21
The sequence 5'-AAUAAA-3'forms parts of the recognition site for polyadenylation of late SV40 mRNAs. Cell (1981) 12.26
Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells. Cell (1979) 10.95
Transcriptional repression by YY1, a human GLI-Krüppel-related protein, and relief of repression by adenovirus E1A protein. Cell (1991) 8.31
The adenovirus type 5 E1A transcriptional control region contains a duplicated enhancer element. Cell (1983) 8.19
Helper-free stocks of recombinant adeno-associated viruses: normal integration does not require viral gene expression. J Virol (1989) 6.69
Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors. J Virol (1996) 6.22
Adenovirus VAI RNA is required for efficient translation of viral mRNAs at late times after infection. Cell (1982) 5.80
Transcriptional control regions of the adenovirus VAI RNA gene. Cell (1980) 5.64
Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein. EMBO J (1998) 4.98
Adenovirus VAI RNA antagonizes the antiviral action of interferon by preventing activation of the interferon-induced eIF-2 alpha kinase. Cell (1986) 4.72
A recombinant plasmid from which an infectious adeno-associated virus genome can be excised in vitro and its use to study viral replication. J Virol (1987) 4.57
Adenovirus early region 4 encodes functions required for efficient DNA replication, late gene expression, and host cell shutoff. J Virol (1985) 4.35
Cellular gene expression altered by human cytomegalovirus: global monitoring with oligonucleotide arrays. Proc Natl Acad Sci U S A (1998) 4.33
YY1 is an initiator sequence-binding protein that directs and activates transcription in vitro. Nature (1991) 4.30
Isolation of deletion and substitution mutants of adenovirus type 5. Cell (1978) 4.29
New region of the simian virus 40 genome required for efficient viral transformation. Proc Natl Acad Sci U S A (1978) 4.24
Human cytomegalovirus IE1 and IE2 proteins block apoptosis. J Virol (1995) 4.22
Wild-type p53 binds to the TATA-binding protein and represses transcription. Proc Natl Acad Sci U S A (1992) 4.06
Adenovirus virus-associated RNA and translation control. J Virol (1991) 3.77
A 64 kd nuclear protein binds to RNA segments that include the AAUAAA polyadenylation motif. Cell (1988) 3.44
A multisubunit factor, CstF, is required for polyadenylation of mammalian pre-mRNAs. Genes Dev (1990) 3.43
Adenovirus early region 1B 58,000-dalton tumor antigen is physically associated with an early region 4 25,000-dalton protein in productively infected cells. J Virol (1984) 3.38
A poly(A) addition site and a downstream termination region are required for efficient cessation of transcription by RNA polymerase II in the mouse beta maj-globin gene. Proc Natl Acad Sci U S A (1987) 3.38
The adenovirus E1B-55K transforming polypeptide modulates transport or cytoplasmic stabilization of viral and host cell mRNAs. Mol Cell Biol (1986) 3.36
Definition of the boundaries of the origin of DNA replication in simian virus 40. Nucleic Acids Res (1978) 3.32
Comparative sequence analysis of the 5' noncoding region of the enteroviruses and rhinoviruses. Virology (1988) 3.30
Use of differential display analysis to assess the effect of human cytomegalovirus infection on the accumulation of cellular RNAs: induction of interferon-responsive RNAs. Proc Natl Acad Sci U S A (1997) 3.25
Altered cellular mRNA levels in human cytomegalovirus-infected fibroblasts: viral block to the accumulation of antiviral mRNAs. J Virol (2001) 3.22
A subset of viral transcripts packaged within human cytomegalovirus particles. Science (2000) 3.19
Human cytomegalovirus tegument protein pp71 (ppUL82) enhances the infectivity of viral DNA and accelerates the infectious cycle. J Virol (1997) 3.16
Functional analysis of adenovirus-5 host-range deletion mutants defective for transformation of rat embryo cells. Cold Spring Harb Symp Quant Biol (1980) 3.15
Adenovirus tripartite leader sequence enhances translation of mRNAs late after infection. Proc Natl Acad Sci U S A (1984) 3.11
Adenovirus VAI RNA prevents phosphorylation of the eukaryotic initiation factor 2 alpha subunit subsequent to infection. Proc Natl Acad Sci U S A (1985) 3.09
A 32-kilodalton protein binds to AU-rich domains in the 3' untranslated regions of rapidly degraded mRNAs. Mol Cell Biol (1991) 3.05
Proteins associated with purified human cytomegalovirus particles. J Virol (1996) 3.01
Conversion of the lac repressor into an allosterically regulated transcriptional activator for mammalian cells. Mol Cell Biol (1990) 3.00
Impact of virus infection on host cell protein synthesis. Annu Rev Biochem (1987) 2.98
The 64-kilodalton subunit of the CstF polyadenylation factor binds to pre-mRNAs downstream of the cleavage site and influences cleavage site location. Mol Cell Biol (1994) 2.94
Interaction between transcription factors Sp1 and YY1. Nature (1993) 2.87
Transcriptional control regions: nucleotide sequence requirements for initiation by RNA polymerase II and III. Curr Top Microbiol Immunol (1981) 2.85
Adenovirus VAI RNA facilitates the initiation of translation in virus-infected cells. Cell (1984) 2.76
Drosophila immune deficiency (IMD) is a death domain protein that activates antibacterial defense and can promote apoptosis. Dev Cell (2001) 2.68
TATA-binding protein-independent initiation: YY1, TFIIB, and RNA polymerase II direct basal transcription on supercoiled template DNA. Cell (1994) 2.68
Nucleotide and amino acid sequence coding for polypeptides of foot-and-mouth disease virus type A12. J Virol (1985) 2.65
Blockage by adenovirus E4orf6 of transcriptional activation by the p53 tumor suppressor. Science (1996) 2.56
Nuclear export of the E1B 55-kDa and E4 34-kDa adenoviral oncoproteins mediated by a rev-like signal sequence. EMBO J (1997) 2.44
A uridylate tract mediates efficient heterogeneous nuclear ribonucleoprotein C protein-RNA cross-linking and functionally substitutes for the downstream element of the polyadenylation signal. Mol Cell Biol (1990) 2.43
Human cytomegalovirus infection inhibits cell cycle progression at multiple points, including the transition from G1 to S. J Virol (1996) 2.41
Replication of wild-type and mutant human cytomegalovirus in life-extended human diploid fibroblasts. J Virol (2000) 2.41
Deletion of the gene encoding the adenovirus 5 early region 1b 21,000-molecular-weight polypeptide leads to degradation of viral and host cell DNA. J Virol (1984) 2.39
A chimeric mammalian transactivator based on the lac repressor that is regulated by temperature and isopropyl beta-D-thiogalactopyranoside. Proc Natl Acad Sci U S A (1991) 2.35
Dissection of overlapping functions within the adenovirus type 5 E1A gene. EMBO J (1984) 2.30
Fragments of the simian virus 40 transforming gene facilitate transformation of rat embryo cells. Proc Natl Acad Sci U S A (1982) 2.29
Transcription termination within the E1A gene of adenovirus induced by insertion of the mouse beta-major globin terminator element. Cell (1985) 2.29
Nucleotide sequence analysis of viable deletion mutants lacking segments of the simian virus 40 genome coding for small t antigen. J Virol (1979) 2.28
Adenovirus E1A protein paradigm viral transactivator. Annu Rev Genet (1989) 2.23
Analysis of adenovirus early region 4-encoded polypeptides synthesized in productively infected cells. J Virol (1987) 2.20
Cocrystal structure of YY1 bound to the adeno-associated virus P5 initiator. Proc Natl Acad Sci U S A (1996) 2.16
The human 64-kDa polyadenylylation factor contains a ribonucleoprotein-type RNA binding domain and unusual auxiliary motifs. Proc Natl Acad Sci U S A (1992) 2.15
The adenovirus type 5 E1A enhancer contains two functionally distinct domains: one is specific for E1A and the other modulates all early units in cis. Cell (1986) 2.14
The C proteins of heterogeneous nuclear ribonucleoprotein complexes interact with RNA sequences downstream of polyadenylation cleavage sites. Mol Cell Biol (1988) 2.14
Adenoviral control regions activated by E1A and the cAMP response element bind to the same factor. Proc Natl Acad Sci U S A (1988) 2.14
Viral transactivating proteins. Annu Rev Genet (1997) 2.12
DNA binding sites for the transcriptional activator/repressor YY1. Nucleic Acids Res (1995) 2.10
Identification of a repeated sequence element required for efficient encapsidation of the adenovirus type 5 chromosome. J Virol (1987) 2.09
Adenovirus type 5 virions can be assembled in vivo in the absence of detectable polypeptide IX. J Virol (1981) 2.07
The visible vessel as an indicator of uncontrolled or recurrent gastrointestinal hemorrhage. N Engl J Med (1979) 2.06
Functional analysis of point mutations in the AAUAAA motif of the SV40 late polyadenylation signal. Nucleic Acids Res (1989) 1.99
Adenovirus E4orf4 protein binds to protein phosphatase 2A, and the complex down regulates E1A-enhanced junB transcription. J Virol (1993) 1.98
Increased anxiety of mice lacking the serotonin1A receptor. Proc Natl Acad Sci U S A (1998) 1.97
Adeno-associated virus P5 promoter contains an adenovirus E1A-inducible element and a binding site for the major late transcription factor. J Virol (1989) 1.96
The MDM2 oncoprotein binds specifically to RNA through its RING finger domain. Mol Med (1996) 1.94
Human cytomegalovirus UL69 protein is required for efficient accumulation of infected cells in the G1 phase of the cell cycle. Proc Natl Acad Sci U S A (2000) 1.91
Sequence-independent autoregulation of the adenovirus type 5 E1A transcription unit. Mol Cell Biol (1985) 1.90
Human cytomagalovirus IE1 and IE2 proteins are mutagenic and mediate "hit-and-run" oncogenic transformation in cooperation with the adenovirus E1A proteins. Proc Natl Acad Sci U S A (1997) 1.85
A multicomponent complex is required for the AAUAAA-dependent cross-linking of a 64-kilodalton protein to polyadenylation substrates. Mol Cell Biol (1990) 1.84
E1B 55-kilodalton-associated protein: a cellular protein with RNA-binding activity implicated in nucleocytoplasmic transport of adenovirus and cellular mRNAs. J Virol (1998) 1.83
Construction of a viable SV40 variant containing two functional origins of DNA replication. Cell (1978) 1.83
An adenovirus early region 4 gene product is required for induction of the infection-specific form of cellular E2F activity. Genes Dev (1989) 1.82
Human cytomegalovirus UL36 protein is dispensable for viral replication in cultured cells. J Virol (1999) 1.80
Early viral proteins in HeLa cells infected with adenovirus type 5 host range mutants. Virology (1980) 1.79
Characterization of the human cytomegalovirus irs1 and trs1 genes: a second immediate-early transcription unit within irs1 whose product antagonizes transcriptional activation. J Virol (1997) 1.79
Oncogenic potential of the adenovirus E4orf6 protein. Proc Natl Acad Sci U S A (1996) 1.78
Virion DNA-independent RNA polymerase from Saccharomyces cerevisiae. Nucleic Acids Res (1980) 1.76
A mutation which alters initiation of transcription by RNA polymerase III on the Ad5 chromosome. Cell (1979) 1.75
Adenovirus terminal protein mediates both nuclear matrix association and efficient transcription of adenovirus DNA. Genes Dev (1990) 1.74
Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression. Mol Cell Biol (1995) 1.73
Human cytomegalovirus UL69 protein induces cells to accumulate in G1 phase of the cell cycle. J Virol (1999) 1.72
Adenovirus L1 52- and 55-kilodalton proteins are required for assembly of virions. J Virol (1989) 1.71
Relief of p53-mediated transcriptional repression by the adenovirus E1B 19-kDa protein or the cellular Bcl-2 protein. Proc Natl Acad Sci U S A (1994) 1.69
The adenovirus E1B 55 kd protein influences mRNA transport via an intranuclear effect on RNA metabolism. EMBO J (1989) 1.67
Simian virus 40 agnoprotein facilitates normal nuclear location of the major capsid polypeptide and cell-to-cell spread of virus. J Virol (1986) 1.67
Genetic analysis of adenoviruses. Curr Top Microbiol Immunol (1984) 1.66
Adenovirus early region 4 34-kilodalton protein directs the nuclear localization of the early region 1B 55-kilodalton protein in primate cells. J Virol (1996) 1.65
pIRS1 and pTRS1 are present in human cytomegalovirus virions. J Virol (1997) 1.61
Adenovirus E4orf4 protein reduces phosphorylation of c-Fos and E1A proteins while simultaneously reducing the level of AP-1. J Virol (1992) 1.61