Published in Development on August 03, 2005
Primary contribution to zebrafish heart regeneration by gata4(+) cardiomyocytes. Nature (2010) 6.69
Pioneer transcription factors: establishing competence for gene expression. Genes Dev (2011) 6.01
Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice. Dev Biol (2008) 2.34
Pioneer factors, genetic competence, and inductive signaling: programming liver and pancreas progenitors from the endoderm. Cold Spring Harb Symp Quant Biol (2008) 2.34
A threshold of GATA4 and GATA6 expression is required for cardiovascular development. Proc Natl Acad Sci U S A (2006) 2.32
Development of the mammalian liver and ventral pancreas is dependent on GATA4. BMC Dev Biol (2007) 1.75
Gata4 is essential for the maintenance of jejunal-ileal identities in the adult mouse small intestine. Mol Cell Biol (2006) 1.71
Pioneer transcription factors in cell reprogramming. Genes Dev (2014) 1.71
Gata6 is an important regulator of mouse pancreas development. Dev Biol (2006) 1.58
New school in liver development: lessons from zebrafish. Hepatology (2009) 1.36
Redundancy and evolution of GATA factor requirements in development of the myocardium. Dev Biol (2007) 1.31
Gata4 directs development of cardiac-inducing endoderm from ES cells. Dev Biol (2009) 1.23
Gata5 and Gata6 are functionally redundant in zebrafish for specification of cardiomyocytes. Dev Biol (2007) 1.19
miR-145 directs intestinal maturation in zebrafish. Proc Natl Acad Sci U S A (2009) 1.19
Mutations in the 3'-untranslated region of GATA4 as molecular hotspots for congenital heart disease (CHD). BMC Med Genet (2007) 1.19
Cardiac regeneration. Curr Top Dev Biol (2012) 1.17
Voltage-gated sodium channels are required for heart development in zebrafish. Circ Res (2010) 1.14
A GATA4-regulated tumor suppressor network represses formation of malignant human astrocytomas. J Exp Med (2011) 1.13
Loss of GATA-6 and GATA-4 in granulosa cells blocks folliculogenesis, ovulation, and follicle stimulating hormone receptor expression leading to female infertility. Endocrinology (2012) 1.01
Common genetic control of haemangioblast and cardiac development in zebrafish. Development (2009) 0.99
Gata4 is required for formation of the genital ridge in mice. PLoS Genet (2013) 0.97
Orchestrating liver development. Development (2015) 0.94
GATA4 and GATA5 are essential for heart and liver development in Xenopus embryos. BMC Dev Biol (2008) 0.94
Direct transcriptional regulation of Gata4 during early endoderm specification is controlled by FoxA2 binding to an intronic enhancer. Dev Biol (2010) 0.93
An endoderm-specific transcriptional enhancer from the mouse Gata4 gene requires GATA and homeodomain protein-binding sites for function in vivo. Dev Dyn (2009) 0.92
A novel GATA4 loss-of-function mutation associated with congenital ventricular septal defect. Pediatr Cardiol (2011) 0.91
Localized rbp4 expression in the yolk syncytial layer plays a role in yolk cell extension and early liver development. BMC Dev Biol (2007) 0.90
Transcriptional networks in liver and intestinal development. Cold Spring Harb Perspect Biol (2012) 0.89
The transcription factor Atonal homolog 8 regulates Gata4 and Friend of Gata-2 during vertebrate development. J Biol Chem (2013) 0.88
An integrative analysis reveals functional targets of GATA6 transcriptional regulation in gastric cancer. Oncogene (2013) 0.87
GATA factors efficiently direct cardiac fate from embryonic stem cells. Development (2013) 0.86
Klf6/copeb is required for hepatic outgrowth in zebrafish and for hepatocyte specification in mouse ES cells. Dev Biol (2010) 0.85
Small heat shock proteins Hspb7 and Hspb12 regulate early steps of cardiac morphogenesis. Dev Biol (2013) 0.85
Function of GATA factors in the adult mouse liver. PLoS One (2013) 0.85
Hypoxia-inducible factor 2 alpha is essential for hepatic outgrowth and functions via the regulation of leg1 transcription in the zebrafish embryo. PLoS One (2014) 0.85
Non-core subunit eIF3h of translation initiation factor eIF3 regulates zebrafish embryonic development. Dev Dyn (2010) 0.84
Zebrafish models of human liver development and disease. Compr Physiol (2013) 0.84
Cellular and molecular basis of liver development. Compr Physiol (2013) 0.84
Zinc in gut-brain interaction in autism and neurological disorders. Neural Plast (2015) 0.83
Regulation of a vascular plexus by gata4 is mediated in zebrafish through the chemokine sdf1a. PLoS One (2012) 0.83
Role of GATA factors in development, differentiation, and homeostasis of the small intestinal epithelium. Am J Physiol Gastrointest Liver Physiol (2014) 0.83
The developmental transcription factor Gata4 is overexpressed in pancreatic ductal adenocarcinoma. Int J Clin Exp Pathol (2009) 0.83
Deciphering the signals specifying the proepicardium. Circ Res (2010) 0.82
The tbx/bHLH transcription factor mga regulates gata4 and organogenesis. Dev Dyn (2010) 0.81
The inferred cardiogenic gene regulatory network in the mammalian heart. PLoS One (2014) 0.80
Mutation spectrum of GATA4 associated with congenital atrial septal defects. Arch Med Sci (2013) 0.80
A Pak1/Erk signaling module acts through Gata6 to regulate cardiovascular development in zebrafish. Dev Cell (2014) 0.79
Carboxy terminus of GATA4 transcription factor is required for its cardiogenic activity and interaction with CDK4. Mech Dev (2014) 0.78
Utilization of Whole Exome Sequencing to Identify Causative Mutations in Familial Congenital Heart Disease. Circ Cardiovasc Genet (2016) 0.78
A reverse genetic approach to test functional redundancy during embryogenesis. J Vis Exp (2010) 0.78
In vivo manifestation of Notch related phenotypes in zebrafish treated with Alzheimer's amyloid reducing gamma-secretase inhibitors. J Neurochem (2010) 0.77
Chromatin "pre-pattern" and epigenetic modulation in the cell fate choice of liver over pancreas in the endoderm. Nucleus (2012) 0.77
Developmental toxicity of diclofenac and elucidation of gene regulation in zebrafish (Danio rerio). Sci Rep (2014) 0.77
Identification and characterization of alternative promoters of zebrafish Rtn-4/Nogo genes in cultured cells and zebrafish embryos. Nucleic Acids Res (2010) 0.76
Chromatin states modify network motifs contributing to cell-specific functions. Sci Rep (2015) 0.76
Cardiac sodium channel regulator MOG1 regulates cardiac morphogenesis and rhythm. Sci Rep (2016) 0.76
Influence of pub Gene Expression on Differentiation of Mouse Embryonic Stem Cells into Derivatives of Ecto-, Meso-, and Endoderm in vitro. Acta Naturae (2009) 0.75
Id2a is required for hepatic outgrowth during liver development in zebrafish. Mech Dev (2015) 0.75
Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis. Proc Natl Acad Sci U S A (2016) 0.75
Origin and evolution of GATA2a and GATA2b in teleosts: insights from tongue sole, Cynoglossus semilaevis. PeerJ (2016) 0.75
GATA6 Plays an Important Role in the Induction of Human Definitive Endoderm, Development of the Pancreas, and Functionality of Pancreatic β Cells. Stem Cell Reports (2017) 0.75
GATA6 is essential for endoderm formation from human pluripotent stem cells. Biol Open (2017) 0.75
Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells. Nat Biotechnol (2010) 9.24
Primary contribution to zebrafish heart regeneration by gata4(+) cardiomyocytes. Nature (2010) 6.69
Evolutionarily conserved gene family important for fat storage. Proc Natl Acad Sci U S A (2007) 1.91
An injury-responsive gata4 program shapes the zebrafish cardiac ventricle. Curr Biol (2013) 1.73
Flow-regulated endothelial S1P receptor-1 signaling sustains vascular development. Dev Cell (2012) 1.62
Anthracycline-induced suppression of GATA-4 transcription factor: implication in the regulation of cardiac myocyte apoptosis. Mol Pharmacol (2003) 1.45
Hepatocyte growth factor induces GATA-4 phosphorylation and cell survival in cardiac muscle cells. J Biol Chem (2002) 1.33
T-box binding sites are required for activity of a cardiac GATA-4 enhancer. Dev Biol (2004) 1.25
Gata4 directs development of cardiac-inducing endoderm from ES cells. Dev Biol (2009) 1.23
Gata5 and Gata6 are functionally redundant in zebrafish for specification of cardiomyocytes. Dev Biol (2007) 1.19
AID stabilizes stem-cell phenotype by removing epigenetic memory of pluripotency genes. Nature (2013) 1.18
Smad1 and Smad5 differentially regulate embryonic hematopoiesis. Blood (2007) 1.16
Sphingosine 1-phosphate signalling. Development (2014) 1.14
Using the zebrafish model to study GATA transcription factors. Semin Cell Dev Biol (2004) 1.10
BMP signaling restricts hemato-vascular development from lateral mesoderm during somitogenesis. Development (2006) 1.07
Retinoid signaling regulates primitive (yolk sac) hematopoiesis. Blood (2002) 1.06
KDR identifies a conserved human and murine hepatic progenitor and instructs early liver development. Cell Stem Cell (2013) 1.06
Smad1 expands the hemangioblast population within a limited developmental window. Blood (2006) 1.05
Regulation of cardiac myocyte apoptosis by the GATA-4 transcription factor. Life Sci (2004) 1.03
Synthesis of 2-substituted 2H-chromenes using potassium vinyltrifluoroborates. Tetrahedron Lett (2008) 1.00
Nanog-like regulates endoderm formation through the Mxtx2-Nodal pathway. Dev Cell (2012) 0.98
Design and synthesis of (E)-1-((3-ethyl-2,4,4-trimethylcyclohex-2-enylidene)methyl-4-substituted benzenes from 1-(2,6,6-trimethylcyclohex-1-enyl)ethanol. Chem Commun (Camb) (2009) 0.98
Angiomodulin is a specific marker of vasculature and regulates vascular endothelial growth factor-A-dependent neoangiogenesis. Circ Res (2009) 0.98
Primitive erythropoiesis is regulated by Smad-dependent signaling in postgastrulation mesoderm. Blood (2003) 0.97
Sphingosine 1-phosphate receptor signaling regulates proper embryonic vascular patterning. J Biol Chem (2012) 0.96
Novel retinoic acid receptor alpha agonists for treatment of kidney disease. PLoS One (2011) 0.95
A forward chemical screen using zebrafish embryos with novel 2-substituted 2H-chromene derivatives. Chem Biol Drug Des (2009) 0.95
A forward chemical screen in zebrafish identifies a retinoic acid derivative with receptor specificity. PLoS One (2010) 0.95
Antagonistic function of the RNA-binding protein HuR and miR-200b in post-transcriptional regulation of vascular endothelial growth factor-A expression and angiogenesis. J Biol Chem (2012) 0.94
An Oct-1 binding site mediates activation of the gata2 promoter by BMP signaling. Nucleic Acids Res (2005) 0.93
Yaf2 inhibits caspase 8-mediated apoptosis and regulates cell survival during zebrafish embryogenesis. J Biol Chem (2006) 0.89
Molecular cloning and developmental expression of the caveolin gene family in the amphibian Xenopus laevis. Biochemistry (2002) 0.89
Translation initiation factor eIF3h targets specific transcripts to polysomes during embryogenesis. Proc Natl Acad Sci U S A (2013) 0.89
Design and synthesis of novel pinacolylboronate containing combretastatin 'antimitotic agent' analogues. Tetrahedron Lett (2009) 0.88
GATA factors efficiently direct cardiac fate from embryonic stem cells. Development (2013) 0.86
Tmem88a mediates GATA-dependent specification of cardiomyocyte progenitors by restricting WNT signaling. Development (2013) 0.85
Small heat shock proteins Hspb7 and Hspb12 regulate early steps of cardiac morphogenesis. Dev Biol (2013) 0.85
Design and Synthesis of Potential New Apoptosis Agents: Hybrid Compounds Containing Perillyl Alcohol and New Constrained Retinoids. Tetrahedron Lett (2010) 0.84
Non-core subunit eIF3h of translation initiation factor eIF3 regulates zebrafish embryonic development. Dev Dyn (2010) 0.84
Smad1 signaling restricts hematopoietic potential after promoting hemangioblast commitment. Blood (2011) 0.84
Hematopoiesis and retinoids: development and disease. Leuk Lymphoma (2003) 0.83
Synthesis of function-oriented 2-phenyl-2H-chromene derivatives using L-pipecolinic acid and substituted guanidine organocatalysts. Tetrahedron Lett (2010) 0.83
Bmp2 and Gata4 function additively to rescue heart tube development in the absence of retinoids. Dev Dyn (2006) 0.83
Regulation of a vascular plexus by gata4 is mediated in zebrafish through the chemokine sdf1a. PLoS One (2012) 0.83
Boron chemicals in diagnosis and therapeutics. Future Med Chem (2013) 0.82
The tbx/bHLH transcription factor mga regulates gata4 and organogenesis. Dev Dyn (2010) 0.81
Regulation of hematopoiesis by the BMP signaling pathway in adult zebrafish. Exp Hematol (2008) 0.81
A maternal Smad protein regulates early embryonic apoptosis in Xenopus laevis. Mol Cell Biol (2002) 0.81
Design and Synthesis of 3,5-Disubstituted 1,2,4-Oxadiazole Containing Retinoids from a Retinoic Acid Receptor Agonist. Tetrahedron Lett (2011) 0.81
Elavl1a regulates zebrafish erythropoiesis via posttranscriptional control of gata1. Blood (2014) 0.80
Tid1 is a Smad-binding protein that can modulate Smad7 activity in developing embryos. Biochem J (2006) 0.79
Cloning and expression pattern of the Xenopus erythropoietin receptor. Gene Expr Patterns (2005) 0.78
A reverse genetic approach to test functional redundancy during embryogenesis. J Vis Exp (2010) 0.78
Silencing of UCHL1 by CpG promoter hyper-methylation is associated with metastatic gastroenteropancreatic well-differentiated neuroendocrine (carcinoid) tumors. Ann Surg Oncol (2014) 0.77
Use of zebrafish in chemical biology and drug discovery. Future Med Chem (2013) 0.77
STAT5 acts as a repressor to regulate early embryonic erythropoiesis. Blood (2006) 0.76
Heart chamber size in zebrafish is regulated redundantly by duplicated tbx2 genes. Dev Dyn (2011) 0.76
Design and synthesis of 3,5-disubstituted boron-containing 1,2,4-oxadiazoles as potential combretastatin A-4 (CA-4) analogs. Tetrahedron Lett (2012) 0.75
Design and synthesis of boron containing potential pan-RAR inverse agonists. Tetrahedron Lett (2012) 0.75
Steady endothelial nitric oxide synthase expression in heart failure. Acta Cardiol (2007) 0.75
Modeling COVID-19 with Human Pluripotent Stem Cell-Derived Cells Reveals Synergistic Effects of Anti-inflammatory Macrophages with ACE2 Inhibition Against SARS-CoV-2. Res Sq (2020) 0.75