Published in Biophys Physicobiol on May 20, 2017
Channelrhodopsin-2, a directly light-gated cation-selective membrane channel. Proc Natl Acad Sci U S A (2003) 15.17
Rhodopsin-like protein from the purple membrane of Halobacterium halobium. Nat New Biol (1971) 14.93
Structure of bacteriorhodopsin at 1.55 A resolution. J Mol Biol (1999) 8.17
Optogenetics. Nat Methods (2010) 6.49
Channelrhodopsin-1: a light-gated proton channel in green algae. Science (2002) 5.73
Resonance Raman studies of the purple membrane. Biochemistry (1977) 3.00
The microbial opsin family of optogenetic tools. Cell (2011) 2.94
Crystal structure of the channelrhodopsin light-gated cation channel. Nature (2012) 2.83
Conversion of channelrhodopsin into a light-gated chloride channel. Science (2014) 2.56
Algal genomes reveal evolutionary mosaicism and the fate of nucleomorphs. Nature (2012) 2.15
NEUROSCIENCE. Natural light-gated anion channels: A family of microbial rhodopsins for advanced optogenetics. Science (2015) 1.99
Microbial and animal rhodopsins: structures, functions, and molecular mechanisms. Chem Rev (2013) 1.93
Channelrhodopsin-2 is a leaky proton pump. Proc Natl Acad Sci U S A (2009) 1.87
Determination of retinal chromophore structure in bacteriorhodopsin with resonance Raman spectroscopy. J Membr Biol (1985) 1.83
Monitoring light-induced structural changes of Channelrhodopsin-2 by UV-visible and Fourier transform infrared spectroscopy. J Biol Chem (2008) 1.83
Leptosphaeria rhodopsin: bacteriorhodopsin-like proton pump from a eukaryote. Proc Natl Acad Sci U S A (2005) 1.75
Evidence for light-induced 13-cis, 14-s-cis isomerization in bacteriorhodopsin obtained by FTIR difference spectroscopy using isotopically labelled retinals. EMBO J (1986) 1.65
Channelrhodopsins: directly light-gated cation channels. Biochem Soc Trans (2005) 1.59
A light-driven sodium ion pump in marine bacteria. Nat Commun (2013) 1.38
Role of internal water molecules in bacteriorhodopsin. Biochim Biophys Acta (2000) 1.37
Resonance Raman studies of the primary photochemical event in visual pigments. Biophys J (1980) 1.33
Optogenetics and translational medicine. Sci Transl Med (2013) 1.31
Conformational changes of channelrhodopsin-2. J Am Chem Soc (2009) 1.28
Light-driven chloride ion transport by halorhodopsin from Natronobacterium pharaonis. 1. The photochemical cycle. Biochemistry (1995) 1.26
Factors affecting the C = N stretching in protonated retinal Schiff base: a model study for bacteriorhodopsin and visual pigments. Biochemistry (1987) 1.21
Channelrhodopsin unchained: structure and mechanism of a light-gated cation channel. Biochim Biophys Acta (2013) 1.18
Functional characterization of flavobacteria rhodopsins reveals a unique class of light-driven chloride pump in bacteria. Proc Natl Acad Sci U S A (2014) 1.16
Mechanism divergence in microbial rhodopsins. Biochim Biophys Acta (2013) 1.14
Transient protonation changes in channelrhodopsin-2 and their relevance to channel gating. Proc Natl Acad Sci U S A (2013) 1.12
Rectification of the channelrhodopsin early conductance. Biophys J (2011) 1.11
The DC gate in Channelrhodopsin-2: crucial hydrogen bonding interaction between C128 and D156. Photochem Photobiol Sci (2010) 1.10
The branched photocycle of the slow-cycling channelrhodopsin-2 mutant C128T. J Mol Biol (2010) 1.10
In channelrhodopsin-2 Glu-90 is crucial for ion selectivity and is deprotonated during the photocycle. J Biol Chem (2012) 1.06
Glutamate residue 90 in the predicted transmembrane domain 2 is crucial for cation flux through channelrhodopsin 2. Biochem Biophys Res Commun (2011) 1.03
Environment around the chromophore in pharaonis phoborhodopsin: mutation analysis of the retinal binding site. Biochim Biophys Acta (2001) 1.02
Tight Asp-85--Thr-89 association during the pump switch of bacteriorhodopsin. Proc Natl Acad Sci U S A (2001) 1.01
Light-driven ion-translocating rhodopsins in marine bacteria. Trends Microbiol (2015) 0.99
Analysis of the factors that influence the C=N stretching frequency of polyene Schiff bases. Implications for bacteriorhodopsin and rhodopsin. Biophys J (1988) 0.99
A blue-shifted light-driven proton pump for neural silencing. J Biol Chem (2013) 0.89
Ultrafast infrared spectroscopy on channelrhodopsin-2 reveals efficient energy transfer from the retinal chromophore to the protein. J Am Chem Soc (2013) 0.89
Water-containing hydrogen-bonding network in the active center of channelrhodopsin. J Am Chem Soc (2014) 0.88
Of ion pumps, sensors and channels - perspectives on microbial rhodopsins between science and history. Biochim Biophys Acta (2013) 0.88
Biophysics of Channelrhodopsin. Annu Rev Biophys (2015) 0.87
Resonance Raman and FTIR spectroscopic characterization of the closed and open states of channelrhodopsin-1. FEBS Lett (2014) 0.87
Early formation of the ion-conducting pore in channelrhodopsin-2. Angew Chem Int Ed Engl (2014) 0.86
Changes in the hydrogen-bonding strength of internal water molecules and cysteine residues in the conductive state of channelrhodopsin-1. J Chem Phys (2014) 0.85
Ion-pumping microbial rhodopsins. Front Mol Biosci (2015) 0.84
Spectroscopic study of a light-driven chloride ion pump from marine bacteria. J Phys Chem B (2014) 0.83
Comparison of the structural changes occurring during the primary phototransition of two different channelrhodopsins from Chlamydomonas algae. Biochemistry (2014) 0.83
Proton transfers in a channelrhodopsin-1 studied by Fourier transform infrared (FTIR) difference spectroscopy and site-directed mutagenesis. J Biol Chem (2015) 0.82
Hydrogen-bonding changes of internal water molecules upon the actions of microbial rhodopsins studied by FTIR spectroscopy. Biochim Biophys Acta (2013) 0.81
Pre-gating conformational changes in the ChETA variant of channelrhodopsin-2 monitored by nanosecond IR spectroscopy. J Am Chem Soc (2015) 0.81
Chimeras of channelrhodopsin-1 and -2 from Chlamydomonas reinhardtii exhibit distinctive light-induced structural changes from channelrhodopsin-2. J Biol Chem (2015) 0.81
A natural light-driven inward proton pump. Nat Commun (2016) 0.78
Structurally Distinct Cation Channelrhodopsins from Cryptophyte Algae. Biophys J (2016) 0.77
Kinetic and vibrational isotope effects of proton transfer reactions in channelrhodopsin-2. Biophys J (2015) 0.76