Published in Angew Chem Int Ed Engl on December 23, 2014
Chimeras of channelrhodopsin-1 and -2 from Chlamydomonas reinhardtii exhibit distinctive light-induced structural changes from channelrhodopsin-2. J Biol Chem (2015) 0.81
Enlightening the photoactive site of channelrhodopsin-2 by DNP-enhanced solid-state NMR spectroscopy. Proc Natl Acad Sci U S A (2015) 0.79
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Crystal structure of the channelrhodopsin light-gated cation channel. Nature (2012) 2.83
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Conversion of channelrhodopsin into a light-gated chloride channel. Science (2014) 2.56
Functional waters in intraprotein proton transfer monitored by FTIR difference spectroscopy. Nature (2005) 2.31
Photoactivation of channelrhodopsin. J Biol Chem (2007) 2.26
Fast manipulation of cellular cAMP level by light in vivo. Nat Methods (2006) 2.15
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Channelrhodopsin-1 initiates phototaxis and photophobic responses in chlamydomonas by immediate light-induced depolarization. Plant Cell (2008) 1.73
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Two open states with progressive proton selectivities in the branched channelrhodopsin-2 photocycle. Biophys J (2010) 1.46
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Proton binding within a membrane protein by a protonated water cluster. Proc Natl Acad Sci U S A (2005) 1.36
Glu 87 of channelrhodopsin-1 causes pH-dependent color tuning and fast photocurrent inactivation. Photochem Photobiol (2009) 1.35
Color-tuned channelrhodopsins for multiwavelength optogenetics. J Biol Chem (2012) 1.34
Evidence for a light-induced H(+) conductance in the eye of the green alga Chlamydomonas reinhardtii. Biophys J (2002) 1.33
Hydrogen-bond switching through a radical pair mechanism in a flavin-binding photoreceptor. Proc Natl Acad Sci U S A (2006) 1.30
The GAP arginine finger movement into the catalytic site of Ras increases the activation entropy. Proc Natl Acad Sci U S A (2008) 1.30
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On the reaction mechanism of adduct formation in LOV domains of the plant blue-light receptor phototropin. J Am Chem Soc (2004) 1.18
Evolution of the channelrhodopsin photocycle model. Chemphyschem (2010) 1.17
H+ -pumping rhodopsin from the marine alga Acetabularia. Biophys J (2006) 1.15
Proton transfer via a transient linear water-molecule chain in a membrane protein. Proc Natl Acad Sci U S A (2011) 1.15
De novo design of conformationally flexible transmembrane peptides driving membrane fusion. Proc Natl Acad Sci U S A (2004) 1.14
N-Ras forms dimers at POPC membranes. Biophys J (2012) 1.13
Recording of blue light-induced energy and volume changes within the wild-type and mutated phot-LOV1 domain from Chlamydomonas reinhardtii. Biophys J (2004) 1.12
Removal of mismatched bases from synthetic genes by enzymatic mismatch cleavage. Nucleic Acids Res (2005) 1.12
Structural basis of slow activation gating in the cardiac I Ks channel complex. Cell Physiol Biochem (2011) 1.11
Rectification of the channelrhodopsin early conductance. Biophys J (2011) 1.11
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In channelrhodopsin-2 Glu-90 is crucial for ion selectivity and is deprotonated during the photocycle. J Biol Chem (2012) 1.06
A phosphoryl transfer intermediate in the GTPase reaction of Ras in complex with its GTPase-activating protein. Proc Natl Acad Sci U S A (2006) 1.06
The assignment of the different infrared continuum absorbance changes observed in the 3000-1800-cm(-1) region during the bacteriorhodopsin photocycle. Biophys J (2004) 1.06
Proteins in action monitored by time-resolved FTIR spectroscopy. Chemphyschem (2005) 1.06
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Theoretical IR spectroscopy based on QM/MM calculations provides changes in charge distribution, bond lengths, and bond angles of the GTP ligand induced by the Ras-protein. Biophys J (2005) 1.02
Fourier transform infrared spectroscopy on the Rap.RapGAP reaction, GTPase activation without an arginine finger. J Biol Chem (2004) 1.02
Surface change of Ras enabling effector binding monitored in real time at atomic resolution. Chembiochem (2007) 1.01
Light-dark adaptation of channelrhodopsin C128T mutant. J Biol Chem (2013) 1.00
Channelrhodopsins of Volvox carteri are photochromic proteins that are specifically expressed in somatic cells under control of light, temperature, and the sex inducer. Plant Physiol (2009) 1.00
Conserved Tyr223(5.58) plays different roles in the activation and G-protein interaction of rhodopsin. J Am Chem Soc (2011) 0.99
Ras and GTPase-activating protein (GAP) drive GTP into a precatalytic state as revealed by combining FTIR and biomolecular simulations. Proc Natl Acad Sci U S A (2012) 0.99
Prediction of a ligand-binding niche within a human olfactory receptor by combining site-directed mutagenesis with dynamic homology modeling. Angew Chem Int Ed Engl (2011) 0.98
The role of key amino acids in the photoactivation pathway of the Synechocystis Slr1694 BLUF domain. Biochemistry (2009) 0.97
Hassallidin A, a glycosylated lipopeptide with antifungal activity from the cyanobacterium Hassallia sp. J Nat Prod (2005) 0.97
Partial agonism in a G Protein-coupled receptor: role of the retinal ring structure in rhodopsin activation. J Biol Chem (2005) 0.97
Effect of channel mutations on the uptake and release of the retinal ligand in opsin. Proc Natl Acad Sci U S A (2012) 0.97
Bimodal activation of different neuron classes with the spectrally red-shifted channelrhodopsin chimera C1V1 in Caenorhabditis elegans. PLoS One (2012) 0.96
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Unravelling the mechanism of dual-specificity GAPs. EMBO J (2010) 0.96
Fast, repetitive light-activation of CaV3.2 using channelrhodopsin 2. Channels (Austin) (2011) 0.95
The phot LOV2 domain and its interaction with LOV1. Biophys J (2005) 0.95
A photochromic histidine kinase rhodopsin (HKR1) that is bimodally switched by ultraviolet and blue light. J Biol Chem (2012) 0.94
Hydrogen bond switching among flavin and amino acid side chains in the BLUF photoreceptor observed by ultrafast infrared spectroscopy. Biophys J (2008) 0.94
Directional proton transfer in membrane proteins achieved through protonated protein-bound water molecules: a proton diode. Angew Chem Int Ed Engl (2010) 0.94
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Role of the arginine finger in Ras.RasGAP revealed by QM/MM calculations. FEBS Lett (2007) 0.93
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Nuclear-gene targeting by using single-stranded DNA avoids illegitimate DNA integration in Chlamydomonas reinhardtii. Eukaryot Cell (2005) 0.92
Characterization of a flavin radical product in a C57M mutant of a LOV1 domain by electron paramagnetic resonance. Biochemistry (2003) 0.92
Blue light induces global and localized conformational changes in the kinase domain of full-length phototropin. Biochemistry (2010) 0.92
Light-induced reactions of Escherichia coli DNA photolyase monitored by Fourier transform infrared spectroscopy. FEBS J (2005) 0.92
Nuclear gene targeting in Chlamydomonas using engineered zinc-finger nucleases. Plant J (2013) 0.90
Towards an understanding of channelrhodopsin function: simulations lead to novel insights of the channel mechanism. J Mol Biol (2013) 0.90
Marker-free automated histopathological annotation of lung tumour subtypes by FTIR imaging. Analyst (2015) 0.89
Insight into catalysis of a unique GTPase reaction by a combined biochemical and FTIR approach. J Mol Biol (2006) 0.89
How does a membrane protein achieve a vectorial proton transfer via water molecules? Chemphyschem (2008) 0.89
Interaction with transducin depletes metarhodopsin III: a regulated retinal storage in visual signal transduction? J Biol Chem (2004) 0.89
Prion protein alpha-to-beta transition monitored by time-resolved Fourier transform infrared spectroscopy. Appl Spectrosc (2007) 0.89
Synthesis and antimicrobial properties of monensin A esters. Bioorg Med Chem Lett (2008) 0.89
Label-free imaging of drug distribution and metabolism in colon cancer cells by Raman microscopy. Analyst (2014) 0.89
Ion selectivity and competition in channelrhodopsins. Biophys J (2013) 0.89
In vivo generation of flavoproteins with modified cofactors. J Mol Biol (2008) 0.89
The specific vibrational modes of GTP in solution and bound to Ras: a detailed theoretical analysis by QM/MM simulations. Phys Chem Chem Phys (2011) 0.89
Structural model of channelrhodopsin. J Biol Chem (2012) 0.88
Water dynamics simulation as a tool for probing proton transfer pathways in a heptahelical membrane protein. Proteins (2005) 0.88
The chromophore structure of the long-lived intermediate of the C128T channelrhodopsin-2 variant. FEBS Lett (2011) 0.87
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Biophysics of Channelrhodopsin. Annu Rev Biophys (2015) 0.87
Simulations of a G protein-coupled receptor homology model predict dynamic features and a ligand binding site. FEBS Lett (2008) 0.87