Published in Dis Markers on May 29, 2017
Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell (2007) 30.22
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature (2002) 28.79
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature (2010) 23.55
Long non-coding RNAs: insights into functions. Nat Rev Genet (2009) 19.61
GENCODE: the reference human genome annotation for The ENCODE Project. Genome Res (2012) 19.19
RNA maps reveal new RNA classes and a possible function for pervasive transcription. Science (2007) 18.59
Evolution and functions of long noncoding RNAs. Cell (2009) 17.54
The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression. Genome Res (2012) 15.41
A coding-independent function of gene and pseudogene mRNAs regulates tumour biology. Nature (2010) 13.82
Genome regulation by long noncoding RNAs. Annu Rev Biochem (2012) 11.70
A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression. Nature (2011) 11.59
Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma. Proc Natl Acad Sci U S A (2011) 10.56
Ceramide triggers budding of exosome vesicles into multivesicular endosomes. Science (2008) 9.42
Long noncoding RNAs: functional surprises from the RNA world. Genes Dev (2009) 9.14
MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancer. Oncogene (2003) 7.90
Long noncoding RNAs and human disease. Trends Cell Biol (2011) 7.59
Modular regulatory principles of large non-coding RNAs. Nature (2012) 7.42
The functional role of long non-coding RNA in human carcinomas. Mol Cancer (2011) 6.37
The product of the mouse Xist gene is a 15 kb inactive X-specific transcript containing no conserved ORF and located in the nucleus. Cell (1992) 6.26
The product of the H19 gene may function as an RNA. Mol Cell Biol (1990) 5.61
Long non-coding RNAs: new players in cell differentiation and development. Nat Rev Genet (2013) 5.48
Ultraconserved regions encoding ncRNAs are altered in human leukemias and carcinomas. Cancer Cell (2007) 5.40
Export of microRNAs and microRNA-protective protein by mammalian cells. Nucleic Acids Res (2010) 5.29
Non-coding RNAs: the architects of eukaryotic complexity. EMBO Rep (2001) 4.74
Characterization of HULC, a novel gene with striking up-regulation in hepatocellular carcinoma, as noncoding RNA. Gastroenterology (2006) 4.70
lncRNAdb: a reference database for long noncoding RNAs. Nucleic Acids Res (2010) 4.49
starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein-RNA interaction networks from large-scale CLIP-Seq data. Nucleic Acids Res (2013) 4.33
HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer. Oncogene (2012) 4.30
starBase: a database for exploring microRNA-mRNA interaction maps from Argonaute CLIP-Seq and Degradome-Seq data. Nucleic Acids Res (2010) 3.99
Activating RNAs associate with Mediator to enhance chromatin architecture and transcription. Nature (2013) 3.98
Long non-coding RNAs and cancer: a new frontier of translational research? Oncogene (2012) 3.83
GAS5, a non-protein-coding RNA, controls apoptosis and is downregulated in breast cancer. Oncogene (2008) 3.79
DD3(PCA3), a very sensitive and specific marker to detect prostate tumors. Cancer Res (2002) 3.78
The landscape of long noncoding RNAs in the human transcriptome. Nat Genet (2015) 3.58
DD3(PCA3)-based molecular urine analysis for the diagnosis of prostate cancer. Eur Urol (2003) 3.52
The long noncoding RNA SChLAP1 promotes aggressive prostate cancer and antagonizes the SWI/SNF complex. Nat Genet (2013) 3.39
NONCODE: an integrated knowledge database of non-coding RNAs. Nucleic Acids Res (2005) 3.16
Long non-coding RNA H19 increases bladder cancer metastasis by associating with EZH2 and inhibiting E-cadherin expression. Cancer Lett (2013) 2.99
Long noncoding RNAs and the genetics of cancer. Br J Cancer (2013) 2.98
LncRNADisease: a database for long-non-coding RNA-associated diseases. Nucleic Acids Res (2012) 2.73
Large intervening non-coding RNA HOTAIR is associated with hepatocellular carcinoma progression. J Int Med Res (2011) 2.64
CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer. Genome Res (2013) 2.57
The melanoma-upregulated long noncoding RNA SPRY4-IT1 modulates apoptosis and invasion. Cancer Res (2011) 2.52
Exosomes biological significance: A concise review. Blood Cells Mol Dis (2006) 2.46
LNCipedia: a database for annotated human lncRNA transcript sequences and structures. Nucleic Acids Res (2012) 2.40
Characterization of human plasma-derived exosomal RNAs by deep sequencing. BMC Genomics (2013) 2.27
Long non-coding RNA: a new player in cancer. J Hematol Oncol (2013) 2.26
Mechanisms of epigenetic inheritance. Curr Opin Cell Biol (2007) 2.20
miRcode: a map of putative microRNA target sites in the long non-coding transcriptome. Bioinformatics (2012) 2.13
ChIPBase: a database for decoding the transcriptional regulation of long non-coding RNA and microRNA genes from ChIP-Seq data. Nucleic Acids Res (2012) 2.11
The long non-coding RNA HOTAIR indicates a poor prognosis and promotes metastasis in non-small cell lung cancer. BMC Cancer (2013) 2.11
Transcriptomic and genomic analysis of human hepatocellular carcinomas and hepatoblastomas. Hepatology (2006) 2.08
Long noncoding RNA: an emerging paradigm of cancer research. Tumour Biol (2013) 2.07
Association of a novel long non-coding RNA in 8q24 with prostate cancer susceptibility. Cancer Sci (2010) 2.03
SNORD-host RNA Zfas1 is a regulator of mammary development and a potential marker for breast cancer. RNA (2011) 2.03
Rapid identification of UCA1 as a very sensitive and specific unique marker for human bladder carcinoma. Clin Cancer Res (2006) 1.97
DIANA-LncBase: experimentally verified and computationally predicted microRNA targets on long non-coding RNAs. Nucleic Acids Res (2012) 1.94
uPM3, a new molecular urine test for the detection of prostate cancer. Urology (2004) 1.91
DD3PCA3 RNA analysis in urine--a new perspective for detecting prostate cancer. Eur Urol (2004) 1.89
Biogenesis of extracellular vesicles (EV): exosomes, microvesicles, retrovirus-like vesicles, and apoptotic bodies. J Neurooncol (2013) 1.88
The long and the short of noncoding RNAs. Curr Opin Cell Biol (2009) 1.87
Human colorectal cancer-specific CCAT1-L lncRNA regulates long-range chromatin interactions at the MYC locus. Cell Res (2014) 1.83
Regulation of mammalian cell differentiation by long non-coding RNAs. EMBO Rep (2012) 1.82
Unique features of long non-coding RNA biogenesis and function. Nat Rev Genet (2015) 1.81
Long noncoding RNAs: Novel insights into hepatocelluar carcinoma. Cancer Lett (2013) 1.80
Kcnq1ot1 noncoding RNA mediates transcriptional gene silencing by interacting with Dnmt1. Development (2010) 1.78
A susceptibility locus for papillary thyroid carcinoma on chromosome 8q24. Cancer Res (2009) 1.77
Overexpression of the long non-coding RNA MEG3 impairs in vitro glioma cell proliferation. J Cell Biochem (2012) 1.75
Concern The functional role of long non-coding RNAs and epigenetics. Biol Proced Online (2014) 1.73
Long non-coding RNA metastasis associated in lung adenocarcinoma transcript 1 derived miniRNA as a novel plasma-based biomarker for diagnosing prostate cancer. Eur J Cancer (2013) 1.73
lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs. Nucleic Acids Res (2014) 1.69
Phenotypic characterization of endometrial stromal sarcoma of the uterus. Cancer Sci (2006) 1.68
Plasma HULC as a promising novel biomarker for the detection of hepatocellular carcinoma. Biomed Res Int (2013) 1.63
UCA1, a long non-coding RNA up-regulated in colorectal cancer influences cell proliferation, apoptosis and cell cycle distribution. Pathology (2014) 1.61
Association of large noncoding RNA HOTAIR expression and its downstream intergenic CpG island methylation with survival in breast cancer. Breast Cancer Res Treat (2012) 1.60
Amplification of PVT-1 is involved in poor prognosis via apoptosis inhibition in colorectal cancers. Br J Cancer (2013) 1.58
Role of long non-coding RNA HULC in cell proliferation, apoptosis and tumor metastasis of gastric cancer: a clinical and in vitro investigation. Oncol Rep (2013) 1.56
Long noncoding RNA ANRIL promotes non-small cell lung cancer cell proliferation and inhibits apoptosis by silencing KLF2 and P21 expression. Mol Cancer Ther (2014) 1.56
Identification of the long non-coding RNA H19 in plasma as a novel biomarker for diagnosis of gastric cancer. Sci Rep (2015) 1.55
Long non-coding RNA in cancer. Int J Mol Sci (2013) 1.52
Long non-coding RNA H19 promotes glioma cell invasion by deriving miR-675. PLoS One (2014) 1.52
Identification of the long non-coding RNA POU3F3 in plasma as a novel biomarker for diagnosis of esophageal squamous cell carcinoma. Mol Cancer (2015) 1.51
Circulating long non-coding RNAs in plasma of patients with gastric cancer. Anticancer Res (2013) 1.49
HOTAIR, a cell cycle-associated long noncoding RNA and a strong predictor of survival, is preferentially expressed in classical and mesenchymal glioma. Neuro Oncol (2013) 1.47
Long noncoding RNAs in cell-fate programming and reprogramming. Cell Stem Cell (2014) 1.47
The Landscape of long noncoding RNA classification. Trends Genet (2015) 1.47
Long non-coding RNA HOTAIR is an independent prognostic marker of metastasis in estrogen receptor-positive primary breast cancer. Breast Cancer Res Treat (2013) 1.46
Comprehensive Genomic Characterization of Long Non-coding RNAs across Human Cancers. Cancer Cell (2015) 1.43
Prostate cancer: diagnostic performance of the PCA3 urine test. Nat Rev Urol (2011) 1.43
Perspectives of Long Non-Coding RNAs in Cancer Diagnostics. Front Genet (2012) 1.41
A central role for long non-coding RNA in cancer. Front Genet (2012) 1.40
HOTAIR long non-coding RNA is a negative prognostic factor not only in primary tumors, but also in the blood of colorectal cancer patients. Carcinogenesis (2014) 1.39
Overexpression of long non-coding RNA UCA1 predicts a poor prognosis in patients with esophageal squamous cell carcinoma. Int J Clin Exp Pathol (2014) 1.39
Identification of a long non-coding RNA as a novel biomarker and potential therapeutic target for metastatic prostate cancer. Oncotarget (2014) 1.38
Imprinting of human H19: allele-specific CpG methylation, loss of the active allele in Wilms tumor, and potential for somatic allele switching. Am J Hum Genet (1993) 1.36
Overexpression of long noncoding RNA PCAT-1 is a novel biomarker of poor prognosis in patients with colorectal cancer. Med Oncol (2013) 1.35
Long non-coding RNAs and human disease. Biochem Soc Trans (2012) 1.35
CCAT2 is a lung adenocarcinoma-specific long non-coding RNA and promotes invasion of non-small cell lung cancer. Tumour Biol (2014) 1.34
Long non-coding RNA ANRIL is upregulated in hepatocellular carcinoma and regulates cell apoptosis by epigenetic silencing of KLF2. J Hematol Oncol (2015) 1.34
BC200 RNA in invasive and preinvasive breast cancer. Carcinogenesis (2004) 1.34
Genetic analysis of amyotrophic lateral sclerosis in the Slovenian population. Neurobiol Aging (2014) 0.77