Published in Int J Mol Sci on July 09, 2017
Chromophore Renewal and Fluorogen-Binding Tags: A Match Made to Last. Sci Rep (2017) 0.75
Specific covalent labeling of recombinant protein molecules inside live cells. Science (1998) 9.32
A general method for the covalent labeling of fusion proteins with small molecules in vivo. Nat Biotechnol (2002) 6.77
HaloTag: a novel protein labeling technology for cell imaging and protein analysis. ACS Chem Biol (2008) 6.00
RNA mimics of green fluorescent protein. Science (2011) 4.22
An engineered protein tag for multiprotein labeling in living cells. Chem Biol (2008) 3.92
Mammalian cell-based optimization of the biarsenical-binding tetracysteine motif for improved fluorescence and affinity. Nat Biotechnol (2005) 3.28
A FlAsH-based FRET approach to determine G protein-coupled receptor activation in living cells. Nat Methods (2005) 3.11
Labeling of fusion proteins with synthetic fluorophores in live cells. Proc Natl Acad Sci U S A (2004) 3.11
A near-infrared fluorophore for live-cell super-resolution microscopy of cellular proteins. Nat Chem (2013) 2.61
Imaging intracellular RNA distribution and dynamics in living cells. Nat Methods (2009) 2.56
Fluorogen-activating single-chain antibodies for imaging cell surface proteins. Nat Biotechnol (2007) 2.45
A general method to improve fluorophores for live-cell and single-molecule microscopy. Nat Methods (2015) 2.36
Fluorescence imaging of cellular metabolites with RNA. Science (2012) 2.23
Aptamers switch on fluorescence of triphenylmethane dyes. J Am Chem Soc (2003) 2.05
Imaging bacterial protein expression using genetically encoded RNA sensors. Nat Methods (2013) 2.00
Oscillations of cyclic AMP in hormone-stimulated insulin-secreting beta-cells. Nature (2006) 1.98
Shedding light on the dark and weakly fluorescent states of green fluorescent proteins. Proc Natl Acad Sci U S A (1999) 1.97
How to obtain labeled proteins and what to do with them. Curr Opin Biotechnol (2010) 1.85
Fluorogenic probes for live-cell imaging of the cytoskeleton. Nat Methods (2014) 1.84
Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex. Science (2008) 1.79
Directed evolution of O6-alkylguanine-DNA alkyltransferase for efficient labeling of fusion proteins with small molecules in vivo. Chem Biol (2003) 1.76
Blue-fluorescent antibodies. Science (2000) 1.71
RNA-based fluorescent biosensors for live cell imaging of second messengers cyclic di-GMP and cyclic AMP-GMP. J Am Chem Soc (2013) 1.67
A superfolding Spinach2 reveals the dynamic nature of trinucleotide repeat-containing RNA. Nat Methods (2013) 1.62
Discovery of regulators of receptor internalization with high-throughput flow cytometry. Mol Pharmacol (2012) 1.61
Structural basis for activity of highly efficient RNA mimics of green fluorescent protein. Nat Struct Mol Biol (2014) 1.58
Modular aptameric sensors. J Am Chem Soc (2004) 1.57
Synthesis of new fluorogenic cyanine dyes and incorporation into RNA fluoromodules. Org Lett (2008) 1.53
Development of SNAP-tag fluorogenic probes for wash-free fluorescence imaging. Chembiochem (2011) 1.51
Chemical probes shed light on protein function. Curr Opin Struct Biol (2007) 1.42
Detection and quantification of beta2AR internalization in living cells using FAP-based biosensor technology. J Biomol Screen (2010) 1.34
Short tetracysteine tags to beta-tubulin demonstrate the significance of small labels for live cell imaging. Mol Biol Cell (2004) 1.31
A rainbow of fluoromodules: a promiscuous scFv protein binds to and activates a diverse set of fluorogenic cyanine dyes. J Am Chem Soc (2008) 1.29
STED nanoscopy in living cells using Fluorogen Activating Proteins. Bioconjug Chem (2009) 1.21
Broccoli: rapid selection of an RNA mimic of green fluorescent protein by fluorescence-based selection and directed evolution. J Am Chem Soc (2014) 1.20
RNA mango aptamer-fluorophore: a bright, high-affinity complex for RNA labeling and tracking. ACS Chem Biol (2014) 1.19
Fluorogen-activating proteins as biosensors of cell-surface proteins in living cells. Cytometry A (2010) 1.17
Pharmacological rescue of the mutant cystic fibrosis transmembrane conductance regulator (CFTR) detected by use of a novel fluorescence platform. Mol Med (2012) 1.15
Transcription monitoring using fused RNA with a dye-binding light-up aptamer as a tag: a blue fluorescent RNA. Chem Commun (Camb) (2008) 1.10
Directed evolution of O6-alkylguanine-DNA alkyltransferase for applications in protein labeling. Protein Eng Des Sel (2006) 1.04
Antibodies for fluorescent molecular rotors. Biochemistry (1993) 1.03
Imaging of RNA in live cells. Curr Opin Chem Biol (2011) 0.97
Real-time measurements of protein dynamics using fluorescence activation-coupled protein labeling method. J Am Chem Soc (2011) 0.97
A strategy for the development of small-molecule-based sensors that strongly fluoresce when bound to a specific RNA. J Am Chem Soc (2005) 0.96
Engineering substrate specificity of O6-alkylguanine-DNA alkyltransferase for specific protein labeling in living cells. Chembiochem (2005) 0.96
Blue fluorescent dye-protein complexes based on fluorogenic cyanine dyes and single chain antibody fragments. Org Biomol Chem (2010) 0.95
Imaging metabolite dynamics in living cells using a Spinach-based riboswitch. Proc Natl Acad Sci U S A (2015) 0.91
Self-Checking Cell-Based Assays for GPCR Desensitization and Resensitization. J Biomol Screen (2014) 0.90
Localization microscopy using noncovalent fluorogen activation by genetically encoded fluorogen-activating proteins. Chemphyschem (2013) 0.89
A fluorogenic probe for SNAP-tagged plasma membrane proteins based on the solvatochromic molecule Nile Red. ACS Chem Biol (2014) 0.89
Development of fluorogenic probes for quick no-wash live-cell imaging of intracellular proteins. J Am Chem Soc (2013) 0.89
High-throughput flow cytometry compatible biosensor based on fluorogen activating protein technology. Cytometry A (2013) 0.88
A fluorogenic TMP-tag for high signal-to-background intracellular live cell imaging. ACS Chem Biol (2013) 0.88
Combining SELEX screening and rational design to develop light-up fluorophore-RNA aptamer pairs for RNA tagging. ACS Chem Biol (2010) 0.88
Fluorogen-activating proteins provide tunable labeling densities for tracking FcεRI independent of IgE. ACS Chem Biol (2014) 0.87
Photoactive yellow protein-based protein labeling system with turn-on fluorescence intensity. J Am Chem Soc (2009) 0.87
Dark dyes-bright complexes: fluorogenic protein labeling. Curr Opin Chem Biol (2015) 0.85
Fluorogenic Probes for Multicolor Imaging in Living Cells. J Am Chem Soc (2016) 0.85
Rapid, specific, no-wash, far-red fluorogen activation in subcellular compartments by targeted fluorogen activating proteins. ACS Chem Biol (2015) 0.85
Light-up properties of complexes between thiazole orange-small molecule conjugates and aptamers. Nucleic Acids Res (2009) 0.84
Small fluorescence-activating and absorption-shifting tag for tunable protein imaging in vivo. Proc Natl Acad Sci U S A (2015) 0.84
Near-instant surface-selective fluorogenic protein quantification using sulfonated triarylmethane dyes and fluorogen activating proteins. Org Biomol Chem (2015) 0.83
"Turn-on" protein fluorescence: in situ formation of cyanine dyes. J Am Chem Soc (2015) 0.82
Development of protein-labeling probes with a redesigned fluorogenic switch based on intramolecular association for no-wash live-cell imaging. Angew Chem Int Ed Engl (2012) 0.82
Fluorogenic Green-Inside Red-Outside (GIRO) Labeling Approach Reveals Adenylyl Cyclase-Dependent Control of BKα Surface Expression. Bioconjug Chem (2015) 0.81
A rapid and affordable screening platform for membrane protein trafficking. BMC Biol (2015) 0.80
Directed evolution of a fluorogen-activating single chain antibody for function and enhanced brightness in the cytoplasm. Mol Biotechnol (2013) 0.79
Solvatochromic and Fluorogenic Dyes as Environment-Sensitive Probes: Design and Biological Applications. Acc Chem Res (2017) 0.79
Super-resolution Imaging of Live Bacteria Cells Using a Genetically Directed, Highly Photostable Fluoromodule. J Am Chem Soc (2016) 0.78
Fluorogenic probes reveal a role of GLUT4 N-glycosylation in intracellular trafficking. Nat Chem Biol (2016) 0.76
Redesign of a Fluorogenic Labeling System To Improve Surface Charge, Brightness, and Binding Kinetics for Imaging the Functional Localization of Bromodomains. Angew Chem Int Ed Engl (2015) 0.76
Chemical biology: green fluorescent RNA. Nature (2004) 0.75
Directed Evolution of a Bright Near-Infrared Fluorescent Rhodopsin Using a Synthetic Chromophore. Cell Chem Biol (2017) 0.75