Published in Eur J Pharmacol on March 17, 1987
The pivotal role of tumour necrosis factor alpha in the development of inflammatory hyperalgesia. Br J Pharmacol (1992) 3.21
A cascade of cytokines mediates mechanical inflammatory hypernociception in mice. Proc Natl Acad Sci U S A (2005) 2.53
Robust increase of cutaneous sensitivity, cytokine production and sympathetic sprouting in rats with localized inflammatory irritation of the spinal ganglia. Neuroscience (2006) 1.78
Interleukin-8 as a mediator of sympathetic pain. Br J Pharmacol (1991) 1.71
Bradykinin initiates cytokine-mediated inflammatory hyperalgesia. Br J Pharmacol (1993) 1.44
Anti-inflammatory and analgesic effects of paeonol in carrageenan-evoked thermal hyperalgesia. Br J Pharmacol (2003) 1.35
Pharmacological modulation of secondary mediator systems--cyclic AMP and cyclic GMP--on inflammatory hyperalgesia. Br J Pharmacol (1999) 1.22
Cytokine-mediated inflammatory hyperalgesia limited by interleukin-10. Br J Pharmacol (1995) 1.17
Oral anti-inflammatory activity of cannabidiol, a non-psychoactive constituent of cannabis, in acute carrageenan-induced inflammation in the rat paw. Naunyn Schmiedebergs Arch Pharmacol (2004) 1.16
Involvement of bradykinin, cytokines, sympathetic amines and prostaglandins in formalin-induced orofacial nociception in rats. Br J Pharmacol (2004) 1.10
Cytokine-mediated inflammatory hyperalgesia limited by interleukin-4. Br J Pharmacol (1999) 1.06
Teleantagonism: A pharmacodynamic property of the primary nociceptive neuron. Proc Natl Acad Sci U S A (2008) 0.98
Treatment with DF 2162, a non-competitive allosteric inhibitor of CXCR1/2, diminishes neutrophil influx and inflammatory hypernociception in mice. Br J Pharmacol (2008) 0.98
The role of interleukins and nitric oxide in the mediation of inflammatory pain and its control by peripheral analgesics. Drugs (1993) 0.96
Atorvastatin inhibits inflammatory hypernociception. Br J Pharmacol (2006) 0.96
Anti-inflammatory and Anti-oxidative Activities of Paeonol and Its Metabolites Through Blocking MAPK/ERK/p38 Signaling Pathway. Inflammation (2016) 0.94
Enhancement of antinociception by coadministration of minocycline and a non-steroidal anti-inflammatory drug indomethacin in naïve mice and murine models of LPS-induced thermal hyperalgesia and monoarthritis. BMC Musculoskelet Disord (2010) 0.91
The role of PKA and PKCepsilon pathways in prostaglandin E2-mediated hypernociception. Br J Pharmacol (2009) 0.91
The critical role of leukotriene B4 in antigen-induced mechanical hyperalgesia in immunised rats. Br J Pharmacol (2003) 0.90
Experimental evaluation of analgesic and anti-inflammatory activity of simvastatin and atorvastatin. Indian J Pharmacol (2012) 0.89
Peripheral analgesic activities of peptides related to alpha-melanocyte stimulating hormone and interleukin-1 beta 193-195. Br J Pharmacol (1992) 0.88
Bradykinin release of TNF-alpha plays a key role in the development of inflammatory hyperalgesia. Agents Actions (1993) 0.87
Caspase-1 is involved in the genesis of inflammatory hypernociception by contributing to peripheral IL-1β maturation. Mol Pain (2010) 0.83
No adrenergic sensitization of afferent neurons in painful sensory polyneuropathy. J Neurol (2005) 0.80
Inhibition of pro-inflammatory mediators: role of Bacopa monniera (L.) Wettst. Inflammopharmacology (2010) 0.80
Pharmacological evaluation and preliminary pharmacokinetics studies of a new diclofenac prodrug without gastric ulceration effect. Int J Mol Sci (2012) 0.79
Tumor necrosis factor, interleukin-1 and interleukin-8 mediate the nociceptive activity of the supernatant of LPS-stimulated macrophages. Mediators Inflamm (1997) 0.79
Central α-adrenoceptors contribute to mustard oil-induced central sensitization in the rat medullary dorsal horn. Neuroscience (2013) 0.76
S14080, a peripheral analgesic acting by release of an endogenous circulating opioid-like substance. Br J Pharmacol (1995) 0.75
Articular inflammation induced by an enzymatically-inactive Lys49 phospholipase A2: activation of endogenous phospholipases contributes to the pronociceptive effect. J Venom Anim Toxins Incl Trop Dis (2017) 0.75
Participation of the NO/cGMP/K+ATP pathway in the antinociception induced by Walker tumor bearing in rats. Braz J Med Biol Res (2012) 0.75
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature (2002) 28.79
Antisense transcription in the mammalian transcriptome. Science (2005) 15.69
Quinolone resistance-determining region in the DNA gyrase gyrA gene of Escherichia coli. Antimicrob Agents Chemother (1990) 11.71
Prostaglandins: their disappearance from and release into the circulation. Nature (1967) 8.66
Nucleotide sequence of cloned cDNA for bovine corticotropin-beta-lipotropin precursor. Nature (1979) 6.56
Quinolone resistance-determining region in the DNA gyrase gyrB gene of Escherichia coli. Antimicrob Agents Chemother (1991) 6.19
Indomethacin and aspirin abolish prostaglandin release from the spleen. Nat New Biol (1971) 5.62
Prostaglandins, aspirin-like drugs and analgesia. Nat New Biol (1972) 4.91
Cloning of the gamma chain of the human IL-2 receptor. Science (1992) 4.50
Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4. Science (1993) 4.39
gyrA and gyrB mutations in quinolone-resistant strains of Escherichia coli. Antimicrob Agents Chemother (1989) 3.67
Loss of aquaporin 4 in lesions of neuromyelitis optica: distinction from multiple sclerosis. Brain (2007) 3.64
Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: spontaneous recovery after spinal cord injury and statistical power needed for therapeutic clinical trials. Spinal Cord (2006) 3.55
On the process of cellular division in Escherichia coli: nucleotide sequence of the gene for penicillin-binding protein 3. Mol Gen Genet (1983) 3.43
Rifampicin resistance and mutation of the rpoB gene in Mycobacterium tuberculosis. FEMS Microbiol Lett (1996) 3.40
Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC. Nat Cell Biol (2001) 3.26
Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2. J Exp Med (2001) 3.23
The pivotal role of tumour necrosis factor alpha in the development of inflammatory hyperalgesia. Br J Pharmacol (1992) 3.21
Prostaglandins, aspirin-like drugs and the oedema of inflammation. Nature (1973) 3.20
Light-dependent translocation of a phytochrome B-GFP fusion protein to the nucleus in transgenic Arabidopsis. J Cell Biol (1999) 3.14
Noggin is a mesenchymally derived stimulator of hair-follicle induction. Nat Cell Biol (1999) 2.99
Diet-dependent shifts in the bacterial population of the rumen revealed with real-time PCR. Appl Environ Microbiol (2001) 2.98
Mutations in the Drosophila dTAK1 gene reveal a conserved function for MAPKKKs in the control of rel/NF-kappaB-dependent innate immune responses. Genes Dev (2001) 2.96
Functional participation of the IL-2 receptor gamma chain in IL-7 receptor complexes. Science (1994) 2.78
Human lymphocytes making rheumatoid factor and antibody to ssDNA belong to Leu-1+ B-cell subset. Science (1987) 2.75
Self-organization of microtubule asters induced in Xenopus egg extracts by GTP-bound Ran. Science (1999) 2.59
A cascade of cytokines mediates mechanical inflammatory hypernociception in mice. Proc Natl Acad Sci U S A (2005) 2.53
The interleukin-2 receptor gamma chain: its role in the multiple cytokine receptor complexes and T cell development in XSCID. Annu Rev Immunol (1996) 2.50
Mechanism of action of quinolones against Escherichia coli DNA gyrase. Antimicrob Agents Chemother (1993) 2.48
The disappearance of bradykinin and eledoisin in the circulation and vascular beds of the cat. Br J Pharmacol Chemother (1967) 2.44
Nucleotide sequence of the asnA gene coding for asparagine synthetase of E. coli K-12. Nucleic Acids Res (1981) 2.42
Guidelines for the conduct of clinical trials for spinal cord injury (SCI) as developed by the ICCP panel: clinical trial outcome measures. Spinal Cord (2006) 2.28
Cloning by functional expression of platelet-activating factor receptor from guinea-pig lung. Nature (1991) 2.28
Host range of human T-cell leukemia virus type I analyzed by a cell fusion-dependent reporter gene activation assay. Virology (1999) 2.21
Cloning, expression, and fatty acid regulation of the human delta-5 desaturase. J Biol Chem (1999) 2.19
Central and peripheral antialgesic action of aspirin-like drugs. Eur J Pharmacol (1978) 2.18
Genetic mutations in exons 3 and 4 of the pancreatic secretory trypsin inhibitor in patients with pancreatitis. J Gastroenterol (2001) 2.17
Proportion of DNA gyrase mutants among quinolone-resistant strains of Pseudomonas aeruginosa. Antimicrob Agents Chemother (1990) 2.17
Involvement of resident macrophages and mast cells in the writhing nociceptive response induced by zymosan and acetic acid in mice. Eur J Pharmacol (2000) 2.16
Recombinant human Fas ligand induces alveolar epithelial cell apoptosis and lung injury in rabbits. Am J Physiol Lung Cell Mol Physiol (2001) 2.16
Functional assignment of the ORF2-iscS-iscU-iscA-hscB-hscA-fdx-ORF3 gene cluster involved in the assembly of Fe-S clusters in Escherichia coli. J Biochem (1999) 2.15
Prostaglandins and the mechanism of analgesia produced by aspirin-like drugs. Br J Pharmacol (1973) 2.07
Selective expression of a novel surface molecule by human Th2 cells in vivo. J Immunol (1999) 2.07
Transplantation of in vitro-expanded fetal neural progenitor cells results in neurogenesis and functional recovery after spinal cord contusion injury in adult rats. J Neurosci Res (2002) 2.06
Interleukin 12-dependent interferon gamma production by CD8alpha+ lymphoid dendritic cells. J Exp Med (1999) 2.05
Activation of endogenous c-fos proto-oncogene expression by human T-cell leukemia virus type I-encoded p40tax protein in the human T-cell line, Jurkat. J Virol (1989) 2.03
Anomalous origin of the left coronary artery from the pulmonary artery. New operative technique. J Thorac Cardiovasc Surg (1993) 2.02
Noggin is required for induction of the hair follicle growth phase in postnatal skin. FASEB J (2001) 1.95
Neutrophils exposed to bacterial lipopolysaccharide upregulate NADPH oxidase assembly. J Clin Invest (1998) 1.95
Enhanced HIV replication in macrophage colony-stimulating factor-treated monocytes. J Immunol (1991) 1.92
MRI of cervical intervertebral discs in asymptomatic subjects. J Bone Joint Surg Br (1998) 1.92
Possible relationship of a 36-megadalton Salmonella enteritidis plasmid to virulence in mice. Infect Immun (1985) 1.91
Differential acute and chronic responses of tumor necrosis factor-deficient mice to experimental brain injury. Proc Natl Acad Sci U S A (1999) 1.91
Age-dependent synuclein pathology following traumatic brain injury in mice. Exp Neurol (2003) 1.89
Transplantation of human neural stem cells for spinal cord injury in primates. J Neurosci Res (2005) 1.88
Identification of two distinct elements in the long terminal repeat of HTLV-I responsible for maximum gene expression. EMBO J (1987) 1.88
Phylogenetic analysis of archaeal 16S rRNA libraries from the rumen suggests the existence of a novel group of archaea not associated with known methanogens. FEMS Microbiol Lett (2001) 1.87
Isolation of bradykinin-potentiating peptides from Bothrops jararaca venom. Biochemistry (1970) 1.86
Modulation of hematopoiesis in mice with a truncated mutant of the interleukin-2 receptor gamma chain. Blood (1996) 1.85
p38 mitogen-activated protein kinase can be involved in transforming growth factor beta superfamily signal transduction in Drosophila wing morphogenesis. Mol Cell Biol (1999) 1.83
Hemodynamic and metabolic effects of low-dose vasopressin infusions in vasodilatory septic shock. Crit Care Med (2001) 1.82
Insulin rescues retinal neurons from apoptosis by a phosphatidylinositol 3-kinase/Akt-mediated mechanism that reduces the activation of caspase-3. J Biol Chem (2001) 1.82
Correlation between myeloperoxidase-quantified neutrophil accumulation and ischemic brain injury in the rat. Effects of neutrophil depletion. Stroke (1994) 1.81
Proceedings: Prostaglandin generation maintains the smooth muscle tone of the rabbit isolated jejunum. Br J Pharmacol (1972) 1.80
The detection and estimation of bradykinin in the circulating blood. Br J Pharmacol Chemother (1967) 1.80
Myosin-actin interaction plays an important role in human immunodeficiency virus type 1 release from host cells. Proc Natl Acad Sci U S A (1995) 1.79
Mechanism of ergonovine-induced hyperconstriction of the large epicardial coronary artery in conscious dogs a month after arterial injury. Circ Res (1992) 1.78
A randomised dose finding study of oral tacrolimus (FK506) therapy in refractory ulcerative colitis. Gut (2006) 1.75
The hyperalgesic effects of prostacyclin and prostaglandin E2. Prostaglandins (1978) 1.74
Interleukin-8 as a mediator of sympathetic pain. Br J Pharmacol (1991) 1.71
Recombinant interleukin-1 and tumor necrosis factor induce neutrophil migration "in vivo" by indirect mechanisms. Agents Actions (1990) 1.71
Cytologic grading of invasive breast carcinoma. Correlation with clinicopathologic variables and predictive value of nodal metastasis. Acta Cytol (2000) 1.68
Negative regulation of Wingless signaling by D-axin, a Drosophila homolog of axin. Science (1999) 1.66
Participation of the sympathetic system in acetic acid-induced writhing in mice. Braz J Med Biol Res (1988) 1.66
DNA sequence and comparison of virulence plasmids from Rhodococcus equi ATCC 33701 and 103. Infect Immun (2000) 1.64
II - Prostaglandin hyperalgesia: the peripheral analgesic activity of morphine, enkephalins and opioid antagonists. Prostaglandins (1979) 1.63
Escherichia coli K12 genomic database. Protein Seq Data Anal (1990) 1.62
HLA DRB4 0101-restricted immunodominant T cell autoepitope of pyruvate dehydrogenase complex in primary biliary cirrhosis: evidence of molecular mimicry in human autoimmune diseases. J Exp Med (1995) 1.61
Immunotherapy of recurrent genital herpes with recombinant herpes simplex virus type 2 glycoproteins D and B: results of a placebo-controlled vaccine trial. J Infect Dis (1997) 1.60
Correlation between centrosome abnormalities and chromosomal instability in human pancreatic cancer cells. Cancer Genet Cytogenet (2001) 1.60
Loss of heterozygosity on chromosome 10 is more extensive in primary (de novo) than in secondary glioblastomas. Lab Invest (2000) 1.59
A broadly neutralizing monoclonal antibody that recognizes the V3 region of human immunodeficiency virus type 1 glycoprotein gp120. Proc Natl Acad Sci U S A (1991) 1.59
Broad-spectrum cardioprotection with adenosine. Ann Thorac Surg (1999) 1.59
Vascular endothelial growth factor (VEGF) mRNA isoform expression pattern is correlated with liver metastasis and poor prognosis in colon cancer. Br J Cancer (1998) 1.58
Soluble decoy receptor 3 is expressed by malignant gliomas and suppresses CD95 ligand-induced apoptosis and chemotaxis. Cancer Res (2001) 1.58
CRTH2, an orphan receptor of T-helper-2-cells, is expressed on basophils and eosinophils and responds to mast cell-derived factor(s). FEBS Lett (1999) 1.57
Expression and state of phosphorylation of the retinoblastoma susceptibility gene product in cycling and noncycling human hematopoietic cells. Proc Natl Acad Sci U S A (1990) 1.57
An electronic pressure-meter nociception paw test for mice. Braz J Med Biol Res (2004) 1.56
Comparative ultrasonographic and angiographic study of carotid arterial lesions in Takayasu's arteritis. Angiology (1997) 1.55
Enzymatic synthesis of steryl glucoside by a particulate preparation from immature soybean seeds. J Biochem (1968) 1.55
Pulse-spray pharmacomechanical thrombolysis for proximal deep vein thrombosis. Eur J Vasc Endovasc Surg (2006) 1.54
IL-8 causes in vivo neutrophil migration by a cell-dependent mechanism. Immunology (1991) 1.54
Inhibition of tumor growth by ribozyme-mediated suppression of aberrant epidermal growth factor receptor gene expression. J Natl Cancer Inst (1998) 1.54
Coronary artery spasm induced in atherosclerotic miniature swine. Science (1983) 1.53
I - Prostaglandin hyperalgesia, a cAMP/Ca2+ dependent process. Prostaglandins (1979) 1.52