Published in EMBO J on May 01, 1988
Transcription termination by nuclear RNA polymerases. Genes Dev (2009) 2.65
Initiation and termination of DNA replication in human rRNA genes. Mol Cell Biol (1993) 2.62
The REB1 site is an essential component of a terminator for RNA polymerase I in Saccharomyces cerevisiae. Mol Cell Biol (1993) 1.87
Cloning and functional characterization of PTRF, a novel protein which induces dissociation of paused ternary transcription complexes. EMBO J (1998) 1.77
Structural perspective on mutations affecting the function of multisubunit RNA polymerases. Microbiol Mol Biol Rev (2006) 1.51
Different domains of the murine RNA polymerase I-specific termination factor mTTF-I serve distinct functions in transcription termination. EMBO J (1995) 1.41
Functional analysis of Arabidopsis thaliana rRNA gene and spacer promoters in vivo and by transient expression. Proc Natl Acad Sci U S A (1993) 1.39
Termination of transcription by yeast RNA polymerase I. Nucleic Acids Res (1989) 1.35
Transcription termination at the chicken beta H-globin gene. Mol Cell Biol (1988) 1.18
Molecular coevolution of mammalian ribosomal gene terminator sequences and the transcription termination factor TTF-I. Proc Natl Acad Sci U S A (1995) 1.10
An undecamer DNA sequence directs termination of human ribosomal gene transcription. Nucleic Acids Res (1990) 1.07
Processing of truncated mouse or human rRNA transcribed from ribosomal minigenes transfected into mouse cells. Mol Cell Biol (1994) 1.06
Identification of a transcript release activity acting on ternary transcription complexes containing murine RNA polymerase I. EMBO J (1997) 0.96
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The Xenopus laevis ribosomal gene terminator contains sequences that both enhance and repress ribosomal transcription. Mol Cell Biol (1989) 0.88
The Reb1-homologue Ydr026c/Nsi1 is required for efficient RNA polymerase I termination in yeast. EMBO J (2012) 0.84
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Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry (1979) 180.95
A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology (1973) 127.36
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res (1983) 124.30
Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids. Cell (1977) 61.24
Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis. Nucleic Acids Res (1981) 35.39
A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: application to components of the Escherichia coli lactose operon regulatory system. Nucleic Acids Res (1981) 24.41
Selective and accurate initiation of transcription at the Ad2 major late promotor in a soluble system dependent on purified RNA polymerase II and DNA. Cell (1979) 19.98
Transcription termination and 3' processing: the end is in site! Cell (1985) 17.46
A transcription terminator located upstream of the mouse rDNA initiation site affects rRNA synthesis. Cell (1986) 3.75
Transcription of cloned eukaryotic ribosomal RNA genes. Annu Rev Biochem (1986) 3.30
Position-dependent sequence elements downstream of AAUAAA are required for efficient rabbit beta-globin mRNA 3' end formation. Cell (1987) 3.25
Nucleotide sequence requirements for specific initiation of transcription by RNA polymerase I. Proc Natl Acad Sci U S A (1982) 3.09
Transcription of mouse rDNA terminates downstream of the 3' end of 28S RNA and involves interaction of factors with repeated sequences in the 3' spacer. Cell (1985) 3.03
Xenopus laevis U2 snRNA genes: tandemly repeated transcription units sharing 5' and 3' flanking homology with other RNA polymerase II transcribed genes. EMBO J (1983) 2.81
Formation of the 3' end of U1 snRNA is directed by a conserved sequence located downstream of the coding region. EMBO J (1985) 2.69
Characterization of three sites of RNA 3' end formation in the Xenopus ribosomal gene spacer. Cell (1986) 2.68
Purification and characterization of a transcription factor that confers promoter specificity to human RNA polymerase I. Mol Cell Biol (1985) 2.65
Sequences required for 3' end formation of human U2 small nuclear RNA. Cell (1985) 2.57
A termination site for Xenopus RNA polymerase I also acts as an element of an adjacent promoter. Cell (1986) 2.52
Species-specific rDNA transcription is due to promoter-specific binding factors. Mol Cell Biol (1984) 2.51
A repeated 18 bp sequence motif in the mouse rDNA spacer mediates binding of a nuclear factor and transcription termination. Cell (1986) 2.46
Formation of stable preinitiation complexes is a prerequisite for ribosomal DNA transcription in vitro. Nucleic Acids Res (1983) 2.44
Regulation of human ribosomal RNA transcription. Proc Natl Acad Sci U S A (1983) 2.25
Transcription of mouse rDNA is regulated by an activated subform of RNA polymerase I. Cell (1987) 2.18
Two distinct promoter elements in the human rRNA gene identified by linker scanning mutagenesis. Mol Cell Biol (1986) 2.09
A purified transcription factor (TIF-IB) binds to essential sequences of the mouse rDNA promoter. Proc Natl Acad Sci U S A (1986) 2.03
Nested control regions promote Xenopus ribosomal RNA synthesis by RNA polymerase I. Cell (1983) 1.99
In vitro mutagenesis and transcriptional analysis of a mouse ribosomal promoter element. Proc Natl Acad Sci U S A (1984) 1.86
Regulation of eukaryotic ribosomal RNA transcription by RNA polymerase modification. Cell (1986) 1.71
Transcription of the tandem array of ribosomal DNA in Drosophila melanogaster does not terminate at any fixed point. EMBO J (1986) 1.54
Formation of the 3' end on U snRNAs requires at least three sequence elements. EMBO J (1986) 1.52
Presence of a limited number of essential nucleotides in the promoter region of mouse ribosomal RNA gene. Nucleic Acids Res (1985) 1.45
Tripartite sequences within and 3' to the sea urchin H2A histone gene display properties associated with a transcriptional termination process. Mol Cell Biol (1986) 1.22
The core promoter of mouse rDNA consists of two functionally distinct domains. Nucleic Acids Res (1986) 1.21
Evolutionary changes of sequences and factors that direct transcription termination of human and mouse ribsomal genes. Mol Cell Biol (1987) 1.20
A 12-base-pair sequence is an essential element of the ribosomal gene terminator in Xenopus laevis. Mol Cell Biol (1987) 1.19
Eucaryotic transcription complexes are specifically associated in large sedimentable structures: rapid isolation of polymerase I, II, and III transcription factors. Mol Cell Biol (1985) 1.04
Transcription of eukaryotic ribosomal RNA gene. Mol Cell Biochem (1986) 0.86
Ribosomal RNA transcription in vitro is species specific. Nature (1982) 4.78
A transcription terminator located upstream of the mouse rDNA initiation site affects rRNA synthesis. Cell (1986) 3.75
Specific transcription of mouse ribosomal DNA in a cell-free system that mimics control in vivo. Proc Natl Acad Sci U S A (1981) 3.57
Nucleotide sequence requirements for specific initiation of transcription by RNA polymerase I. Proc Natl Acad Sci U S A (1982) 3.09
Transcription of mouse rDNA terminates downstream of the 3' end of 28S RNA and involves interaction of factors with repeated sequences in the 3' spacer. Cell (1985) 3.03
Ribosome biogenesis and cell growth: mTOR coordinates transcription by all three classes of nuclear RNA polymerases. Oncogene (2006) 2.77
NoRC--a novel member of mammalian ISWI-containing chromatin remodeling machines. EMBO J (2001) 2.67
A repeated 18 bp sequence motif in the mouse rDNA spacer mediates binding of a nuclear factor and transcription termination. Cell (1986) 2.46
Formation of stable preinitiation complexes is a prerequisite for ribosomal DNA transcription in vitro. Nucleic Acids Res (1983) 2.44
Transcription complex formation at the mouse rDNA promoter involves the stepwise association of four transcription factors and RNA polymerase I. J Biol Chem (1991) 2.38
Mapping of a mouse ribosomal DNA promoter by in vitro transcription. Nucleic Acids Res (1981) 2.26
A growth-dependent transcription initiation factor (TIF-IA) interacting with RNA polymerase I regulates mouse ribosomal RNA synthesis. EMBO J (1990) 2.26
Acetylation of TAF(I)68, a subunit of TIF-IB/SL1, activates RNA polymerase I transcription. EMBO J (2001) 2.24
Molecular mechanisms mediating methylation-dependent silencing of ribosomal gene transcription. Mol Cell (2001) 2.24
Amino acid starvation affects the initiation frequency of nucleolar RNA polymerase. Cell (1976) 2.23
The nucleotide sequence of the initiation region of the ribosomal transcription unit from mouse. Nucleic Acids Res (1981) 2.16
p53 represses ribosomal gene transcription. Oncogene (1999) 2.08
Phosphorylation by G1-specific cdk-cyclin complexes activates the nucleolar transcription factor UBF. EMBO J (1999) 2.04
Cell cycle-dependent regulation of RNA polymerase I transcription: the nucleolar transcription factor UBF is inactive in mitosis and early G1. Proc Natl Acad Sci U S A (1999) 2.04
A purified transcription factor (TIF-IB) binds to essential sequences of the mouse rDNA promoter. Proc Natl Acad Sci U S A (1986) 2.03
Mitotic silencing of human rRNA synthesis: inactivation of the promoter selectivity factor SL1 by cdc2/cyclin B-mediated phosphorylation. EMBO J (1998) 2.01
Growth-dependent regulation of rRNA synthesis is mediated by a transcription initiation factor (TIF-IA). Nucleic Acids Res (1985) 1.99
The nucleolar transcription factor mUBF is phosphorylated by casein kinase II in the C-terminal hyperacidic tail which is essential for transactivation. EMBO J (1992) 1.94
TIF-IA, the factor mediating growth-dependent control of ribosomal RNA synthesis, is the mammalian homolog of yeast Rrn3p. EMBO Rep (2000) 1.91
A TBP-containing multiprotein complex (TIF-IB) mediates transcription specificity of murine RNA polymerase I. Nucleic Acids Res (1993) 1.88
In vitro mutagenesis and transcriptional analysis of a mouse ribosomal promoter element. Proc Natl Acad Sci U S A (1984) 1.86
Specific interaction of the murine transcription termination factor TTF I with class-I RNA polymerases. Nature (1990) 1.86
Function of the growth-regulated transcription initiation factor TIF-IA in initiation complex formation at the murine ribosomal gene promoter. Mol Cell Biol (1993) 1.85
Mechanism of repression of RNA polymerase I transcription by the retinoblastoma protein. Mol Cell Biol (1997) 1.82
Nucleotide sequence of wild-type hepatitis A virus GBM in comparison with two cell culture-adapted variants. J Virol (1994) 1.80
Cloning and functional characterization of PTRF, a novel protein which induces dissociation of paused ternary transcription complexes. EMBO J (1998) 1.77
Control of nucleolar RNA synthesis by the intracellular pool sizes of ATP and GTP. Cell (1976) 1.77
Characterization of a cloned ribosomal fragment from mouse which contains the 18S coding region and adjacent spacer sequences. Nucleic Acids Res (1979) 1.76
Dual role of the nucleolar transcription factor UBF: trans-activator and antirepressor. Proc Natl Acad Sci U S A (1992) 1.72
RNA polymerase I transcription on nucleosomal templates: the transcription termination factor TTF-I induces chromatin remodeling and relieves transcriptional repression. EMBO J (1997) 1.71
Activation of mammalian ribosomal gene transcription requires phosphorylation of the nucleolar transcription factor UBF. Nucleic Acids Res (1995) 1.69
Isolation and functional characterization of TIF-IB, a factor that confers promoter specificity to mouse RNA polymerase I. Nucleic Acids Res (1990) 1.68
3'-end formation of mouse pre-rRNA involves both transcription termination and a specific processing reaction. Genes Dev (1989) 1.65
Efficient transcription of a protein-coding gene from the RNA polymerase I promoter in transfected cells. Proc Natl Acad Sci U S A (1985) 1.63
Termination of mammalian rDNA replication: polar arrest of replication fork movement by transcription termination factor TTF-I. Cell (1997) 1.61
High mobility group 1 protein is not stably associated with the chromosomes of somatic cells. J Cell Biol (1997) 1.60
The RNA polymerase I-specific transcription initiation factor UBF is associated with transcriptionally active and inactive ribosomal genes. Chromosoma (1993) 1.51
Cloning of murine RNA polymerase I-specific TAF factors: conserved interactions between the subunits of the species-specific transcription initiation factor TIF-IB/SL1. Proc Natl Acad Sci U S A (1997) 1.48
Purification and characterization of TTFI, a factor that mediates termination of mouse ribosomal DNA transcription. Mol Cell Biol (1988) 1.47
TTF-I determines the chromatin architecture of the active rDNA promoter. EMBO J (1998) 1.46
The HMG box-containing nucleolar transcription factor UBF interacts with a specific subunit of RNA polymerase I. EMBO J (1994) 1.44
TBP-associated factors interact with DNA and govern species specificity of RNA polymerase I transcription. EMBO J (1994) 1.44
Limited proteolysis unmasks specific DNA-binding of the murine RNA polymerase I-specific transcription termination factor TTFI. J Mol Biol (1992) 1.42
Different domains of the murine RNA polymerase I-specific termination factor mTTF-I serve distinct functions in transcription termination. EMBO J (1995) 1.41
Purification, assay, and properties of RNA polymerase I and class I-specific transcription factors in mouse. Methods Enzymol (1996) 1.39
Structural organization of mouse rDNA: comparison of transcribed and non-transcribed regions. Mol Gen Genet (1980) 1.39
The N-terminal domain of the human TATA-binding protein plays a role in transcription from TATA-containing RNA polymerase II and III promoters. EMBO J (1994) 1.37
DNA-dependent protein kinase: a potent inhibitor of transcription by RNA polymerase I. Genes Dev (1995) 1.34
Phosphorylation of UBF at serine 388 is required for interaction with RNA polymerase I and activation of rDNA transcription. Proc Natl Acad Sci U S A (2001) 1.33
Drastic rise of intracellular adenosine(5')tetraphospho(5')adenosine correlates with onset of DNA synthesis in eukaryotic cells. Eur J Biochem (1984) 1.31
Mammalian RNA polymerase I exists as a holoenzyme with associated basal transcription factors. J Mol Biol (1998) 1.28
The nucleolar transcription activator UBF relieves Ku antigen-mediated repression of mouse ribosomal gene transcription. Nucleic Acids Res (1993) 1.27
A novel promoter in the mouse rDNA spacer is active in vivo and in vitro. EMBO J (1987) 1.26
TIF-IC, a factor involved in both transcription initiation and elongation of RNA polymerase I. EMBO J (1994) 1.24
Species specificity of transcription by RNA polymerase I. Curr Opin Genet Dev (1995) 1.23
Mitotic phosphorylation of the TBP-containing factor SL1 represses ribosomal gene transcription. J Mol Biol (1998) 1.23
Constitutive and strong association of PAF53 with RNA polymerase I. Chromosoma (1997) 1.22
The core promoter of mouse rDNA consists of two functionally distinct domains. Nucleic Acids Res (1986) 1.21
Evolutionary changes of sequences and factors that direct transcription termination of human and mouse ribsomal genes. Mol Cell Biol (1987) 1.20
A 140-base-pair repetitive sequence element in the mouse rRNA gene spacer enhances transcription by RNA polymerase I in a cell-free system. Proc Natl Acad Sci U S A (1990) 1.19
Overlapping functions of the pRb family in the regulation of rRNA synthesis. Mol Cell Biol (2001) 1.18
A neuroprotective phase precedes striatal degeneration upon nucleolar stress. Cell Death Differ (2013) 1.16
Sequence-specific transactivators counteract topoisomerase II-mediated inhibition of in vitro transcription by RNA polymerases I and II. Nucleic Acids Res (1993) 1.16
Mechanism of transcription termination: PTRF interacts with the largest subunit of RNA polymerase I and dissociates paused transcription complexes from yeast and mouse. Mol Gen Genet (1999) 1.13
DEDD, a novel death effector domain-containing protein, targeted to the nucleolus. EMBO J (1998) 1.12
Molecular coevolution of mammalian ribosomal gene terminator sequences and the transcription termination factor TTF-I. Proc Natl Acad Sci U S A (1995) 1.10
The amino-terminal domain of the transcription termination factor TTF-I causes protein oligomerization and inhibition of DNA binding. Nucleic Acids Res (1996) 1.10
An undecamer DNA sequence directs termination of human ribosomal gene transcription. Nucleic Acids Res (1990) 1.07
Processing of truncated mouse or human rRNA transcribed from ribosomal minigenes transfected into mouse cells. Mol Cell Biol (1994) 1.06
Spacer sequences downstream of the 28S RNA coding region are part of the mouse rDNA transcription unit. Nucleic Acids Res (1985) 1.06
Mapping of replication initiation sites in the mouse ribosomal gene cluster. Chromosoma (1996) 1.05
The transcript release factor PTRF augments ribosomal gene transcription by facilitating reinitiation of RNA polymerase I. Nucleic Acids Res (2001) 1.04
Regulation of ATP pools, rRNA and DNA synthesis in 3T3 cells in response to serum or hypoxanthine. Eur J Biochem (1977) 1.04
Mutational events in consecutive passages of hepatitis A virus strain GBM during cell culture adaptation. Virology (1994) 1.02
TFIIS binds to mouse RNA polymerase I and stimulates transcript elongation and hydrolytic cleavage of nascent rRNA. Mol Gen Genet (1996) 1.00
Noncoding transcripts in sense and antisense orientation regulate the epigenetic state of ribosomal RNA genes. Cold Spring Harb Symp Quant Biol (2011) 1.00
Molecular cloning of RPA2, the gene encoding the second largest subunit of mouse RNA polymerase I. Genomics (1996) 1.00
Expression of an mRNA coding gene under the control of an RNA polymerase I promoter. EMBO J (1983) 0.98
ATPase and GTPase activities isolated from rat liver ribosomes. Eur J Biochem (1974) 0.98
Synthesis of RNA molecules larger than 45 S by isolated rat-liver nucleoli. Eur J Biochem (1975) 0.96
Identification of a transcript release activity acting on ternary transcription complexes containing murine RNA polymerase I. EMBO J (1997) 0.96
Pre-ribosomal RNA synthesis in isolated rat-liver nucleoli. Eur J Biochem (1973) 0.95
Natural point mutations within rat rDNA transcription terminator elements reveal the functional importance of single bases for factor binding and termination. Nucleic Acids Res (1987) 0.93
Structural analysis of mouse rDNA: coincidence between nuclease hypersensitive sites, DNA curvature and regulatory elements in the intergenic spacer. Nucleic Acids Res (1997) 0.91
PAF67, a novel protein that is associated with the initiation-competent form of RNA polymerase I. Biol Chem (2001) 0.89
Trans-acting factors involved in species-specificity and control of mouse ribosomal gene transcription. Mol Cell Biochem (1991) 0.89
Oligomerization of the transcription termination factor TTF-I: implications for the structural organization of ribosomal transcription units. Nucleic Acids Res (1997) 0.88
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