Published in EMBO J on November 01, 1986
The yeast homologue of U3 snRNA. EMBO J (1987) 3.74
Function of the mammalian La protein: evidence for its action in transcription termination by RNA polymerase III. EMBO J (1989) 3.13
Alternative 3'-end processing of U5 snRNA by RNase III. Genes Dev (1997) 2.25
Alternative promoter usage of the Fos-responsive gene Fit-1 generates mRNA isoforms coding for either secreted or membrane-bound proteins related to the IL-1 receptor. EMBO J (1994) 2.02
Elements required for transcription initiation of the human U2 snRNA gene coincide with elements required for snRNA 3' end formation. EMBO J (1988) 1.97
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The Xenopus U2 gene PSE is a single, compact, element required for transcription initiation and 3' end formation. Nucleic Acids Res (1989) 1.43
Sequence requirements for premature transcription arrest within the first intron of the mouse c-fos gene. Mol Cell Biol (1991) 1.36
Transcription of the human U2 snRNA genes continues beyond the 3' box in vivo. EMBO J (1999) 1.32
The highly conserved U small nuclear RNA 3'-end formation signal is quite tolerant to mutation. Mol Cell Biol (1987) 1.32
The mouse ribosomal gene terminator consists of three functionally separable sequence elements. EMBO J (1988) 1.26
The different positioning of the proximal sequence element in the Xenopus RNA polymerase II and III snRNA promoters is a key determinant which confers RNA polymerase III specificity. Nucleic Acids Res (1991) 1.21
Properties of a U1 RNA enhancer-like sequence. Nucleic Acids Res (1987) 1.21
Functional analysis of the sea urchin U7 small nuclear RNA. Mol Cell Biol (1988) 1.20
Initiation and termination of human U1 RNA transcription requires the concerted action of multiple flanking elements. Nucleic Acids Res (1989) 1.19
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Octamer and SPH motifs in the U1 enhancer cooperate to activate U1 RNA gene expression. Mol Cell Biol (1990) 1.05
The 3' ends of human pre-snRNAs are produced by RNA polymerase II CTD-dependent RNA processing. EMBO J (2003) 1.04
Multiple functional motifs in the chicken U1 RNA gene enhancer. Mol Cell Biol (1987) 1.02
Transcription of a nematode trans-spliced leader RNA requires internal elements for both initiation and 3' end-formation. EMBO J (1990) 1.02
U1-like snRNAs lacking complementarity to canonical 5' splice sites. RNA (2006) 1.02
Activity of chimeric U small nuclear RNA (snRNA)/mRNA genes in transfected protoplasts of Nicotiana plumbaginifolia: U snRNA 3'-end formation and transcription initiation can occur independently in plants. Mol Cell Biol (1993) 0.99
A mutation in a single gene of Schizosaccharomyces pombe affects the expression of several snRNAs and causes defects in RNA processing. EMBO J (1990) 0.96
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DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A (1977) 790.54
Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol Cell Biol (1982) 116.75
New M13 vectors for cloning. Methods Enzymol (1983) 90.74
Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter. Nucleic Acids Res (1984) 86.56
Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids. Cell (1977) 61.24
Oligonucleotide-directed mutagenesis of DNA fragments cloned into M13 vectors. Methods Enzymol (1983) 17.47
Transcription termination and 3' processing: the end is in site! Cell (1985) 17.46
Human beta-globin pre-mRNA synthesized in vitro is accurately spliced in Xenopus oocyte nuclei. Cell (1983) 9.77
U2 as well as U1 small nuclear ribonucleoproteins are involved in premessenger RNA splicing. Cell (1985) 8.85
Multiple factors including the small nuclear ribonucleoproteins U1 and U2 are necessary for pre-mRNA splicing in vitro. Cell (1985) 6.85
Transcription of the beta-like globin genes and pseudogenes of the goat in a cell-free system. Nucleic Acids Res (1981) 6.63
The 5' terminus of the RNA moiety of U1 small nuclear ribonucleoprotein particles is required for the splicing of messenger RNA precursors. Cell (1984) 6.25
SnRNAs, SnRNPs, and RNA processing. Annu Rev Biochem (1982) 5.28
Small RNA species of the HeLa cell: metabolism and subcellular localization. Cell (1976) 5.27
3' editing of mRNAs: sequence requirements and involvement of a 60-nucleotide RNA in maturation of histone mRNA precursors. Proc Natl Acad Sci U S A (1984) 4.99
Nuclear segregation of U2 snRNA requires binding of specific snRNP proteins. Cell (1985) 4.98
Requirement of stereospecific alignments for initiation from the simian virus 40 early promoter. Nature (1986) 4.77
Formation of the 3' end of histone mRNA by post-transcriptional processing. Nature (1984) 4.75
Splicing of messenger RNA precursors is inhibited by antisera to small nuclear ribonucleoprotein. Cell (1983) 4.42
An enhancer-like sequence within the Xenopus U2 gene promoter facilitates the formation of stable transcription complexes. Nature (1985) 3.80
The cDNA sequences of the sea urchin U7 small nuclear RNA suggest specific contacts between histone mRNA precursor and U7 RNA during RNA processing. EMBO J (1984) 3.36
Biochemical complementation with RNA in the Xenopus oocyte: a small RNA is required for the generation of 3' histone mRNA termini. Cell (1983) 3.36
Transcription of a gene for human U1 small nuclear RNA. Cell (1982) 2.93
Orientation-dependent transcriptional activator upstream of a human U2 snRNA gene. Mol Cell Biol (1985) 2.87
Xenopus laevis U2 snRNA genes: tandemly repeated transcription units sharing 5' and 3' flanking homology with other RNA polymerase II transcribed genes. EMBO J (1983) 2.81
Formation of the 3' end of U1 snRNA is directed by a conserved sequence located downstream of the coding region. EMBO J (1985) 2.69
Sequences required for 3' end formation of human U2 small nuclear RNA. Cell (1985) 2.57
The two embryonic U1 RNA genes of Xenopus laevis have both common and gene-specific transcription signals. EMBO J (1985) 2.52
Synthesis of human U1 RNA. II. Identification of two regions of the promoter essential for transcription initiation at position +1. J Biol Chem (1984) 2.46
Genetic complementation in the Xenopus oocyte: co-expression of sea urchin histone and U7 RNAs restores 3' processing of H3 pre-mRNA in the oocyte. EMBO J (1986) 2.29
Xenopus laevis U1 snRNA genes: characterisation of transcriptionally active genes reveals major and minor repeated gene families. EMBO J (1984) 2.08
Transcription signals in embryonic Xenopus laevis U1 RNA genes. EMBO J (1985) 2.07
Human U2 and U1 RNA genes use similar transcription signals. EMBO J (1984) 2.01
Intracellular site of U1 small nuclear RNA processing and ribonucleoprotein assembly. J Cell Biol (1984) 1.81
The 3' end of drosophila histone H3 mRNA is produced by a processing activity in vitro. Cell (1984) 1.69
Transcription boundaries of U1 small nuclear RNA. Mol Cell Biol (1985) 1.36
Predicting DNA duplex stability from the base sequence. Proc Natl Acad Sci U S A (1986) 21.73
CRM1 is an export receptor for leucine-rich nuclear export signals. Cell (1997) 18.60
Molecular cloning of the plasmid RP4 primase region in a multi-host-range tacP expression vector. Gene (1986) 13.92
Polyadenylic acid sequences: role in conversion of nuclear RNA into messenger RNA. Science (1971) 10.54
The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs. Cell (1995) 9.98
Nucleocytoplasmic transport. Science (1996) 8.76
Cyclin/PCNA is the auxiliary protein of DNA polymerase-delta. Nature (1987) 8.28
Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells. Immunity (1999) 7.78
HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses. Proc Natl Acad Sci U S A (1997) 6.92
Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice. Science (1996) 6.70
Right ventricular dysplasia: a report of 24 adult cases. Circulation (1982) 6.54
Complete sequence of the staphylococcal gene encoding protein A. A gene evolved through multiple duplications. J Biol Chem (1984) 5.94
Genes specifically expressed at growth arrest of mammalian cells. Cell (1988) 5.61
Cap trimethylation of U snRNA is cytoplasmic and dependent on U snRNP protein binding. Cell (1986) 5.59
Ran induces spindle assembly by reversing the inhibitory effect of importin alpha on TPX2 activity. Cell (2001) 5.33
Translation of MuLV and MSV RNAs in nuclease-treated reticulocyte extracts: enhancement of the gag-pol polypeptide with yeast suppressor tRNA. Cell (1978) 5.31
Beta-COP, a 110 kd protein associated with non-clathrin-coated vesicles and the Golgi complex, shows homology to beta-adaptin. Cell (1991) 5.10
The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus. EMBO J (1997) 5.08
Nuclear export of different classes of RNA is mediated by specific factors. J Cell Biol (1994) 4.99
Nuclear segregation of U2 snRNA requires binding of specific snRNP proteins. Cell (1985) 4.98
Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120. Nature (1995) 4.95
A yeast nucleolar protein related to mammalian fibrillarin is associated with small nucleolar RNA and is essential for viability. EMBO J (1989) 4.91
Monomethylated cap structures facilitate RNA export from the nucleus. Cell (1990) 4.72
Virus-receptor interaction in an adenovirus system. J Virol (1968) 4.69
Identification of the RNA binding segment of human U1 A protein and definition of its binding site on U1 snRNA. EMBO J (1989) 4.69
A novel method for site-directed mutagenesis: its application to an eukaryotic tRNAPro gene promoter. EMBO J (1982) 4.67
Major determinants of the specificity of interaction between small nuclear ribonucleoproteins U1A and U2B'' and their cognate RNAs. Nature (1990) 4.67
A nuclear cap binding protein complex involved in pre-mRNA splicing. Cell (1994) 4.56
Addition of polyadenylate sequences to virus-specific RNA during adenovirus replication. Proc Natl Acad Sci U S A (1971) 4.48
Cloning of the human cDNA for the U1 RNA-associated 70K protein. EMBO J (1986) 4.43
Role of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitment. Immunity (1997) 4.19
A general method to select for M13 clones carrying base pair substitution mutants constructed in vitro. Nucleic Acids Res (1983) 4.14
Dominant-negative mutants of importin-beta block multiple pathways of import and export through the nuclear pore complex. EMBO J (1997) 4.06
Homology of 54K protein of signal-recognition particle, docking protein and two E. coli proteins with putative GTP-binding domains. Nature (1989) 4.05
A cap-binding protein complex mediating U snRNA export. Nature (1995) 3.89
Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation. Nature (1999) 3.84
Isolation and characterization of adenovirus messenger ribonucleic acid in productive infection. J Virol (1972) 3.83
An enhancer-like sequence within the Xenopus U2 gene promoter facilitates the formation of stable transcription complexes. Nature (1985) 3.80
Identification of hSRP1 alpha as a functional receptor for nuclear localization sequences. Science (1995) 3.79
Early events of virus-cell interaction in an adenovirus system. J Virol (1969) 3.68
Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear assembly. Nat Cell Biol (2001) 3.67
Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion. EMBO J (1994) 3.60
The liver-specific transcription factor LF-B1 contains a highly diverged homeobox DNA binding domain. Cell (1989) 3.51
Fungal small nuclear ribonucleoproteins share properties with plant and vertebrate U-snRNPs. EMBO J (1987) 3.50
Identification of a nuclear export receptor for tRNA. Curr Biol (1998) 3.49
Inducible expression vectors incorporating the Escherichia coli atpE translational initiation region. Gene (1987) 3.46
The return of Phineas Gage: clues about the brain from the skull of a famous patient. Science (1994) 3.40
U1 snRNP inhibits pre-mRNA polyadenylation through a direct interaction between U1 70K and poly(A) polymerase. Mol Cell (1998) 3.39
Regulation of fast inactivation of cloned mammalian IK(A) channels by cysteine oxidation. Nature (1991) 3.30
Structural proteins of adenoviruses. X. Isolation and topography of low molecular weight antigens from the virion of adenovirus type 2. Virology (1973) 3.26
The trimethylguanosine cap structure of U1 snRNA is a component of a bipartite nuclear targeting signal. Cell (1990) 3.24
Unrelated animal viruses share receptors. Nature (1976) 3.24
Interleukin 6 is required for the development of collagen-induced arthritis. J Exp Med (1998) 3.20
In vitro assembly of U1 snRNPs. EMBO J (1987) 3.18
DNA chain length markers and the influence of base composition on electrophoretic mobility of oligodeoxyribonucleotides in polyacrylamide-gels. Nucleic Acids Res (1979) 3.17
CHOP (GADD153) and its oncogenic variant, TLS-CHOP, have opposing effects on the induction of G1/S arrest. Genes Dev (1994) 3.12
Specific alterations of coxsackievirus B3 eluted from HeLa cells. J Virol (1971) 3.10
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Nucleocytoplasmic transport: the last 200 nanometers. Cell (1998) 3.00
A new species of virus-coded low molecular weight RNA from cells infected with adenovirus type 2. Cell (1976) 3.00
Cell-specific expression of a transfected human alpha 1-antitrypsin gene. Cell (1985) 2.99
Gene for staphylococcal protein A. Proc Natl Acad Sci U S A (1983) 2.97
Common and interchangeable elements in the promoters of genes transcribed by RNA polymerase iii. Cell (1983) 2.94
Cell type-specific activation of actin genes in the early amphibian embryo. Nature (1984) 2.91
Promoter of a eukaryotic tRNAPro gene is composed of three noncontiguous regions. Proc Natl Acad Sci U S A (1982) 2.91
Hydroxyapatite chromatography and formamide denaturation of adenovirus DNA. J Virol (1973) 2.90
PHAX, a mediator of U snRNA nuclear export whose activity is regulated by phosphorylation. Cell (2000) 2.88
A nuclear cap-binding complex binds Balbiani ring pre-mRNA cotranscriptionally and accompanies the ribonucleoprotein particle during nuclear export. J Cell Biol (1996) 2.84
Transformation reveals a chromosomal locus of the gene(s) for methicillin resistance in Staphylococcus aureus. J Bacteriol (1975) 2.83
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Xenopus laevis U2 snRNA genes: tandemly repeated transcription units sharing 5' and 3' flanking homology with other RNA polymerase II transcribed genes. EMBO J (1983) 2.81
A role for the M9 transport signal of hnRNP A1 in mRNA nuclear export. J Cell Biol (1997) 2.74
CCAAT enhancer- binding protein beta is required for normal hepatocyte proliferation in mice after partial hepatectomy. J Clin Invest (1998) 2.74
Processing of adenovirus specific nuclear RNA during virus replication. Virology (1972) 2.71
Inhibition of influenza virus ribonucleic acid polymerase by ribavirin triphosphate. Antimicrob Agents Chemother (1977) 2.71
Cis- and trans-acting elements responsible for the cell-specific expression of the human alpha 1-antitrypsin gene. EMBO J (1987) 2.69
An improved positive selection plasmid vector constructed by oligonucleotide mediated mutagenesis. Nucleic Acids Res (1983) 2.69
Cell proliferation inhibited by MyoD1 independently of myogenic differentiation. Nature (1990) 2.68
Elevated levels of interleukin-6 in unstable angina. Circulation (1996) 2.66
Cloned neuronal IK(A) channels reopen during recovery from inactivation. Nature (1991) 2.65
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Importin provides a link between nuclear protein import and U snRNA export. Cell (1996) 2.65
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Further evidence on the nuclear origin and transfer to the cytoplasm of polyadenylic acid sequences in mammalian cell RNA. J Mol Biol (1973) 2.61
Purification of a NF1-like DNA-binding protein from rat liver and cloning of the corresponding cDNA. EMBO J (1988) 2.60
Structure of the human alpha 1-acid glycoprotein gene: sequence homology with other human acute phase protein genes. Nucleic Acids Res (1985) 2.59
Hybridization maps of early and late messenger RNA sequences on the adenovirus type 2 genome. J Mol Biol (1976) 2.58
The human U1 snRNP-specific U1A protein inhibits polyadenylation of its own pre-mRNA. Cell (1993) 2.58
Partial purification and characterization of early and late endosomes from yeast. Identification of four novel proteins. J Biol Chem (1993) 2.55
The NMR structure of the 38 kDa U1A protein - PIE RNA complex reveals the basis of cooperativity in regulation of polyadenylation by human U1A protein. Nat Struct Biol (2000) 2.53
Isolation and characterization of multiple human genes homologous to the oncogenes of avian erythroblastosis virus. EMBO J (1983) 2.52
Nucleocytoplasmic transport: Ran, beta and beyond. Trends Cell Biol (2001) 2.50
A nuclear cap-binding complex facilitates association of U1 snRNP with the cap-proximal 5' splice site. Genes Dev (1996) 2.50
A new general approach for the simultaneous chemical synthesis of large numbers of oligonucleotides: segmental solid supports. Nucleic Acids Res (1983) 2.48
A transcription factor which binds to the enhancers of SV40, immunoglobulin heavy chain and U2 snRNA genes. Nature (1987) 2.48
Nup145p is required for nuclear export of mRNA and binds homopolymeric RNA in vitro via a novel conserved motif. Cell (1994) 2.45
Diversity in the signals required for nuclear accumulation of U snRNPs and variety in the pathways of nuclear transport. J Cell Biol (1991) 2.45
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