Published in ACS Chem Biol on November 13, 2017
Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines. Nature (2010) 10.66
Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. Diabetes (2002) 10.49
Evaluation of tumor-size response metrics to predict overall survival in Western and Chinese patients with first-line metastatic colorectal cancer. J Clin Oncol (2013) 5.55
Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds. Science (2013) 4.94
Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes. Diabetes (2005) 4.31
Association between adverse clinical outcome in human disease caused by novel influenza A H7N9 virus and sustained viral shedding and emergence of antiviral resistance. Lancet (2013) 3.83
Retrograde light-guided laryngoscopy for tracheal intubation: clinical practice and comparison with conventional direct laryngoscopy. Anesthesiology (2013) 3.22
Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms. Nat Cell Biol (2002) 2.95
Skeletal involution by age-associated oxidative stress and its acceleration by loss of sex steroids. J Biol Chem (2007) 2.73
A large number of novel coding small open reading frames in the intergenic regions of the Arabidopsis thaliana genome are transcribed and/or under purifying selection. Genome Res (2007) 2.72
Identification of gene expression profile of dorsal root ganglion in the rat peripheral axotomy model of neuropathic pain. Proc Natl Acad Sci U S A (2002) 2.60
Follicular T-helper cell recruitment governed by bystander B cells and ICOS-driven motility. Nature (2013) 2.52
Interaction with vesicle luminal protachykinin regulates surface expression of delta-opioid receptors and opioid analgesia. Cell (2005) 2.52
Mediterranean diet and magnetic resonance imaging-assessed cerebrovascular disease. Ann Neurol (2011) 2.44
Facilitation of μ-opioid receptor activity by preventing δ-opioid receptor-mediated codegradation. Neuron (2011) 2.42
Identification of three interferon-inducible cellular enzymes that inhibit the replication of hepatitis C virus. J Virol (2007) 2.40
Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation. Nat Cell Biol (2010) 2.37
Oxidative stress antagonizes Wnt signaling in osteoblast precursors by diverting beta-catenin from T cell factor- to forkhead box O-mediated transcription. J Biol Chem (2007) 2.37
Cell stiffness is a biomarker of the metastatic potential of ovarian cancer cells. PLoS One (2012) 2.23
Enhanced detection of low abundance human plasma proteins using a tandem IgY12-SuperMix immunoaffinity separation strategy. Mol Cell Proteomics (2008) 2.08
An infectious disease of ducks caused by a newly emerged Tembusu virus strain in mainland China. Virology (2011) 2.05
Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules. Cell Res (2010) 2.04
Intertransversalis fascia approach in urologic laparoscopic operations. Arch Surg (2012) 2.03
The draft genome of the parasitic nematode Trichinella spiralis. Nat Genet (2011) 2.03
Direct observation of thymine dimer repair in DNA by photolyase. Proc Natl Acad Sci U S A (2005) 2.01
Haploidentical transplantation using T cell replete peripheral blood stem cells and myeloablative conditioning in patients with high-risk hematologic malignancies who lack conventional donors is well tolerated and produces excellent relapse-free survival: results of a prospective phase II trial. Biol Blood Marrow Transplant (2012) 1.97
Uterine massage to reduce blood loss after vaginal delivery: a randomized controlled trial. Obstet Gynecol (2013) 1.96
Replication of a cytopathic strain of bovine viral diarrhea virus activates PERK and induces endoplasmic reticulum stress-mediated apoptosis of MDBK cells. J Virol (2002) 1.93
Three immunomarker support vector machines-based prognostic classifiers for stage IB non-small-cell lung cancer. J Clin Oncol (2009) 1.91
Mixed infection and the genesis of influenza virus diversity. J Virol (2009) 1.88
A methyl transferase links the circadian clock to the regulation of alternative splicing. Nature (2010) 1.88
Kinase-mediated regulation of common transcription factors accounts for the bone-protective effects of sex steroids. J Clin Invest (2003) 1.84
Electronic signatures of all four DNA nucleosides in a tunneling gap. Nano Lett (2010) 1.83
FoxO-mediated defense against oxidative stress in osteoblasts is indispensable for skeletal homeostasis in mice. Cell Metab (2010) 1.81
Suppression of autophagy in osteocytes mimics skeletal aging. J Biol Chem (2013) 1.80
Th9 cells promote antitumor immune responses in vivo. J Clin Invest (2012) 1.80
The estrogen receptor-alpha in osteoclasts mediates the protective effects of estrogens on cancellous but not cortical bone. Mol Endocrinol (2010) 1.79
The risk factors for hypoxemia in children younger than 5 years old undergoing rigid bronchoscopy for foreign body removal. Anesth Analg (2009) 1.75
Exome sequencing generates high quality data in non-target regions. BMC Genomics (2012) 1.72
Inhibition of inflammatory pain by activating B-type natriuretic peptide signal pathway in nociceptive sensory neurons. J Neurosci (2010) 1.71
Coexpression of delta- and mu-opioid receptors in nociceptive sensory neurons. Proc Natl Acad Sci U S A (2010) 1.70
Thymus-specific deletion of insulin induces autoimmune diabetes. EMBO J (2009) 1.70
Exosomes derived from human umbilical cord mesenchymal stem cells alleviate liver fibrosis. Stem Cells Dev (2012) 1.68
Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus. Proc Natl Acad Sci U S A (2010) 1.63
Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells. Proc Natl Acad Sci U S A (2013) 1.62
Size-dependent localization and penetration of ultrasmall gold nanoparticles in cancer cells, multicellular spheroids, and tumors in vivo. ACS Nano (2012) 1.62
Mapping hydration dynamics around a protein surface. Proc Natl Acad Sci U S A (2007) 1.61
Genome-wide reverse genetics framework to identify novel functions of the vertebrate secretome. PLoS One (2006) 1.60
LncRNAs expression signatures of renal clear cell carcinoma revealed by microarray. PLoS One (2012) 1.59
Activation of delta opioid receptors induces receptor insertion and neuropeptide secretion. Neuron (2003) 1.57
Critical mechanical conditions around neovessels in carotid atherosclerotic plaque may promote intraplaque hemorrhage. Atherosclerosis (2012) 1.56
Exosomes derived from human bone marrow mesenchymal stem cells promote tumor growth in vivo. Cancer Lett (2011) 1.55
Ultrafast dynamics and anionic active states of the flavin cofactor in cryptochrome and photolyase. J Am Chem Soc (2008) 1.55
Genome of the Chinese tree shrew. Nat Commun (2013) 1.55
Assessing moral distress in respiratory care practitioners. Crit Care Med (2006) 1.55
Quantitative chemical imaging with multiplex stimulated Raman scattering microscopy. J Am Chem Soc (2012) 1.51
Common variants in HSPB7 and FRMD4B associated with advanced heart failure. Circ Cardiovasc Genet (2010) 1.51
Postnatal intracerebroventricular exposure to neuropeptide Y causes weight loss in female adult rats. Am J Physiol Regul Integr Comp Physiol (2003) 1.51
Increased lipid oxidation causes oxidative stress, increased peroxisome proliferator-activated receptor-gamma expression, and diminished pro-osteogenic Wnt signaling in the skeleton. J Biol Chem (2009) 1.50
Triggering of toll-like receptor-4 in human multiple myeloma cells promotes proliferation and alters cell responses to immune and chemotherapy drug attack. Cancer Biol Ther (2011) 1.50
Activation of the hedgehog pathway in human hepatocellular carcinomas. Carcinogenesis (2006) 1.49
Temporary balloon occlusion of inferior vena cava in resection of renal tumor with vena cava thrombus extension. Urology (2009) 1.49
Factors influencing the removal of fluoride from aqueous solution by calcined Mg-Al-CO3 layered double hydroxides. J Hazard Mater (2005) 1.49
Applying narrow-band imaging in complement with white-light imaging cystoscopy in the detection of urothelial carcinoma of the bladder. Urol Oncol (2011) 1.48
C₆₀ exposure augments cardiac ischemia/reperfusion injury and coronary artery contraction in Sprague Dawley rats. Toxicol Sci (2014) 1.47
PEG-based hydrogels as an in vitro encapsulation platform for testing controlled beta-cell microenvironments. Acta Biomater (2005) 1.46
Aberrant Forkhead box O1 function is associated with impaired hepatic metabolism. Endocrinology (2006) 1.46
Peregrine and saker falcon genome sequences provide insights into evolution of a predatory lifestyle. Nat Genet (2013) 1.45
Dynamics and mechanism of cyclobutane pyrimidine dimer repair by DNA photolyase. Proc Natl Acad Sci U S A (2011) 1.45
The effect of carvedilol treatment on chronic heart failure in pediatric patients with dilated cardiomyopathy: a prospective, randomized-controlled study. Pediatr Cardiol (2012) 1.42
The products of the thermal decomposition of CH3CHO. J Chem Phys (2011) 1.41
Effect of linear ablation on spectral components of atrial fibrillation. Heart Rhythm (2010) 1.41
Exercise training increases intramyocellular lipid and oxidative capacity in older adults. Am J Physiol Endocrinol Metab (2004) 1.41
Serum 25-hydroxyvitamin D concentrations and prevalence estimates of hypovitaminosis D in the U.S. population based on assay-adjusted data. J Nutr (2012) 1.40
Evolving renorrhaphy technique for retroperitoneal laparoscopic partial nephrectomy: single-surgeon series. Int J Urol (2014) 1.40
Outcomes and complications related to the management of Bosniak cystic renal lesions. AJR Am J Roentgenol (2015) 1.40
Sensory reconstruction of a finger pulp defect using a dorsal homodigital island flap. Plast Reconstr Surg (2012) 1.40
Dynamics and mechanism of repair of ultraviolet-induced (6-4) photoproduct by photolyase. Nature (2010) 1.40
Single-cell imaging of retinal ganglion cell apoptosis with a cell-penetrating, activatable peptide probe in an in vivo glaucoma model. Proc Natl Acad Sci U S A (2009) 1.40
Transurethral partial cystectomy with continuous wave laser for bladder carcinoma. J Urol (2009) 1.39
The synthesis of SERS-active gold nanoflower tags for in vivo applications. ACS Nano (2008) 1.38
Characterization of bundled and individual triple-walled carbon nanotubes by resonant Raman spectroscopy. ACS Nano (2013) 1.38
Transient versus sustained phosphorylation and nuclear accumulation of ERKs underlie anti-versus pro-apoptotic effects of estrogens. J Biol Chem (2004) 1.38
Control of salicylic acid synthesis and systemic acquired resistance by two members of a plant-specific family of transcription factors. Proc Natl Acad Sci U S A (2010) 1.36
Estrogen receptor-α signaling in osteoblast progenitors stimulates cortical bone accrual. J Clin Invest (2012) 1.36
Hedgehog signaling is activated in subsets of esophageal cancers. Int J Cancer (2006) 1.34
An improved cell-penetrating, caspase-activatable, near-infrared fluorescent peptide for apoptosis imaging. Bioconjug Chem (2009) 1.34
Overexpression of miR-429 induces mesenchymal-to-epithelial transition (MET) in metastatic ovarian cancer cells. Gynecol Oncol (2011) 1.33
Protein hydration dynamics and molecular mechanism of coupled water-protein fluctuations. J Am Chem Soc (2009) 1.33
Novel nicotine oxidoreductase-encoding gene involved in nicotine degradation by Pseudomonas putida strain S16. Appl Environ Microbiol (2008) 1.33
Glucocorticoids and tumor necrosis factor α increase oxidative stress and suppress Wnt protein signaling in osteoblasts. J Biol Chem (2011) 1.32
Effect of axial force on the performance of micromachined vibratory rate gyroscopes. Sensors (Basel) (2010) 1.32
The tiger genome and comparative analysis with lion and snow leopard genomes. Nat Commun (2013) 1.32
Efficacy and safety of bevacizumab plus chemotherapy in Chinese patients with metastatic colorectal cancer: a randomized phase III ARTIST trial. Chin J Cancer (2011) 1.32
Regulatory T cells limit vascular endothelial injury and prevent pulmonary hypertension. Circ Res (2011) 1.31
Genome-wide variation of cytosine modifications between European and African populations and the implications for complex traits. Genetics (2013) 1.31