Bovine papillomavirus contains multiple transforming genes.

PubWeight™: 6.73‹?› | Rank: Top 1%

🔗 View Article (PMC 397187)

Published in Proc Natl Acad Sci U S A on February 01, 1985

Authors

Y C Yang, H Okayama, P M Howley

Articles citing this

(truncated to the top 100)

Different human cervical carcinoma cell lines show similar transcription patterns of human papillomavirus type 18 early genes. EMBO J (1986) 7.60

Structural and transcriptional analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines. J Virol (1987) 6.65

Presence and expression of human papillomavirus sequences in human cervical carcinoma cell lines. Am J Pathol (1985) 6.18

Trans-activation of the human immunodeficiency virus long terminal repeat sequence by DNA viruses. Proc Natl Acad Sci U S A (1986) 4.89

E5 open reading frame of bovine papillomavirus type 1 encodes a transforming gene. J Virol (1986) 4.04

The BPV1-E2 trans-acting protein can be either an activator or a repressor of the HPV18 regulatory region. EMBO J (1987) 3.86

Human papillomavirus type 16 DNA cooperates with activated ras in transforming primary cells. EMBO J (1987) 3.81

Comparison of the in vitro transforming activities of human papillomavirus types. EMBO J (1988) 3.81

Differential promoter utilization by the bovine papillomavirus in transformed cells and productively infected wart tissues. EMBO J (1987) 3.77

Bovine papillomavirus transcriptional regulation: localization of the E2-responsive elements of the long control region. J Virol (1987) 3.66

Trans-activation of an upstream early gene promoter of bovine papilloma virus-1 by a product of the viral E2 gene. EMBO J (1987) 3.65

Quantitative keratinocyte assay detects two biological activities of human papillomavirus DNA and identifies viral types associated with cervical carcinoma. EMBO J (1988) 3.61

Transcriptional trans-activation by the human papillomavirus type 16 E2 gene product. J Virol (1987) 3.24

E2 polypeptides encoded by bovine papillomavirus type 1 form dimers through the common carboxyl-terminal domain: transactivation is mediated by the conserved amino-terminal domain. Proc Natl Acad Sci U S A (1989) 3.18

Translation of open reading frame E5 of bovine papillomavirus is required for its transforming activity. Proc Natl Acad Sci U S A (1986) 3.17

Oncogenic and nononcogenic human genital papillomaviruses generate the E7 mRNA by different mechanisms. J Virol (1989) 3.02

The major human papillomavirus protein in cervical cancers is a cytoplasmic phosphoprotein. J Virol (1987) 2.90

Mutational analysis of cis elements involved in E2 modulation of human papillomavirus type 16 P97 and type 18 P105 promoters. J Virol (1990) 2.90

Identification of the HPV-16 E6 protein from transformed mouse cells and human cervical carcinoma cell lines. EMBO J (1987) 2.84

Identification of human papillomavirus type 18 transforming genes in immortalized and primary cells. J Virol (1989) 2.76

Bovine papillomavirus type 1 3' early region transformation and plasmid maintenance functions. J Virol (1986) 2.62

The E6-E7 region of human papillomavirus type 18 is sufficient for transformation of NIH 3T3 and rat-1 cells. J Virol (1987) 2.60

Human papillomavirus types 6 and 11 mRNAs from genital condylomata acuminata. J Virol (1987) 2.57

Identification of early proteins of the human papilloma viruses type 16 (HPV 16) and type 18 (HPV 18) in cervical carcinoma cells. EMBO J (1987) 2.56

The human papillomavirus type 18 (HPV18) E2 gene product is a repressor of the HPV18 regulatory region in human keratinocytes. J Virol (1989) 2.50

Sequences homologous to 5' splice sites are required for the inhibitory activity of papillomavirus late 3' untranslated regions. Mol Cell Biol (1994) 2.49

Transient replication of bovine papilloma virus type 1 plasmids: cis and trans requirements. Proc Natl Acad Sci U S A (1986) 2.49

Establishment of papillomavirus infection is enhanced by promyelocytic leukemia protein (PML) expression. Proc Natl Acad Sci U S A (2004) 2.43

Bovine papillomavirus type 1 encodes two forms of a transcriptional repressor: structural and functional analysis of new viral cDNAs. J Virol (1989) 2.38

Enhancers and trans-acting E2 transcriptional factors of papillomaviruses. J Virol (1987) 2.36

Bovine papilloma virus-transformed cells contain multiple E2 proteins. Proc Natl Acad Sci U S A (1988) 2.29

Genetic and biochemical definition of the bovine papillomavirus E5 transforming protein. EMBO J (1987) 2.23

Nonsense mutation in open reading frame E2 of bovine papillomavirus DNA. J Virol (1986) 2.22

Characterization of a transcriptional promoter of human papillomavirus 18 and modulation of its expression by simian virus 40 and adenovirus early antigens. J Virol (1987) 2.21

Identification of the human papilloma virus-1a E4 gene products. EMBO J (1986) 2.21

The bovine papillomavirus E6 oncoprotein interacts with paxillin and disrupts the actin cytoskeleton. Proc Natl Acad Sci U S A (1997) 2.00

Transforming activity of human papillomavirus type 16 DNA sequence in a cervical cancer. Proc Natl Acad Sci U S A (1986) 1.99

The chromosomal gene structure and two mRNAs for human granulocyte colony-stimulating factor. EMBO J (1986) 1.98

Human papillomavirus type 16 open reading frame E7 encodes a transforming gene for rat 3Y1 cells. J Virol (1988) 1.97

Complementation of a bovine papilloma virus low-copy-number mutant: evidence for a temporal requirement of the complementing gene. Mol Cell Biol (1986) 1.96

A transcription factor with homology to the AP-1 family links RNA transcription and DNA replication in the lytic cycle of Epstein-Barr virus. EMBO J (1993) 1.96

Bovine papillomavirus mutant temperature sensitive for transformation, replication and transactivation. EMBO J (1988) 1.89

Continued expression of HPV-16 E7 protein is required for maintenance of the transformed phenotype of cells co-transformed by HPV-16 plus EJ-ras. EMBO J (1989) 1.84

Bromodomain protein 4 mediates the papillomavirus E2 transcriptional activation function. J Virol (2006) 1.81

Molecular cloning and nucleotide sequence of deer papillomavirus. J Virol (1985) 1.78

Identification of a transforming gene of human papillomavirus type 16. J Virol (1989) 1.75

A bovine papillomavirus type 1-encoded modulator function is dispensable for transient viral replication but is required for establishment of the stable plasmid state. J Virol (1986) 1.74

The E5 oncoprotein of bovine papillomavirus binds to a 16 kd cellular protein. EMBO J (1990) 1.72

The E6/E7 promoter of extrachromosomal HPV16 DNA in cervical cancers escapes from cellular repression by mutation of target sequences for YY1. EMBO J (1994) 1.71

Accumulation of RNA homologous to human papillomavirus type 16 open reading frames in genital precancers. J Virol (1988) 1.70

The human papillomavirus type 6 and 16 E5 proteins are membrane-associated proteins which associate with the 16-kilodalton pore-forming protein. J Virol (1993) 1.67

Conserved chromosomal positions of dual domains of the ets protooncogene in cats, mice, and humans. Proc Natl Acad Sci U S A (1986) 1.67

Bovine papillomavirus type 1 E1 replication-defective mutants are altered in their transcriptional regulation. J Virol (1988) 1.67

Phenotypic analysis of bovine papillomavirus type 1 E2 repressor mutants. J Virol (1990) 1.65

Efficient transactivation and morphologic transformation by bovine papillomavirus genes expressed from a bovine papillomavirus/simian virus 40 recombinant virus. Proc Natl Acad Sci U S A (1988) 1.62

The bovine papillomavirus P2443 promoter is E2 trans-responsive: evidence for E2 autoregulation. EMBO J (1988) 1.61

Dose-dependent regulation of the early promoter of human papillomavirus type 18 by the viral E2 protein. J Virol (1997) 1.59

Mutational analysis of the 3' open reading frames and the splice junction at nucleotide 3225 of bovine papillomavirus type 1. J Virol (1987) 1.58

Evidence for cooperativity between E2 binding sites in E2 trans-regulation of bovine papillomavirus type 1. J Virol (1988) 1.55

Transforming activity of a 16-amino-acid segment of the bovine papillomavirus E5 protein linked to random sequences of hydrophobic amino acids. J Virol (1989) 1.54

Identification of a novel constitutive enhancer element and an associated binding protein: implications for human papillomavirus type 11 enhancer regulation. J Virol (1989) 1.52

Open reading frames E6 and E7 of bovine papillomavirus type 1 are both required for full transformation of mouse C127 cells. J Virol (1989) 1.52

Proteins encoded by the bovine papillomavirus E1 open reading frame: expression in heterologous systems and in virally transformed cells. J Virol (1990) 1.49

Bovine papillomavirus type 1 E2 transcriptional regulators directly bind two cellular transcription factors, TFIID and TFIIB. J Virol (1995) 1.48

Identification and mapping of human papillomavirus type 1 RNA transcripts recovered from plantar warts and infected epithelial cell cultures. J Virol (1987) 1.44

Bovine papillomavirus E2 gene regulates expression of the viral E5 transforming gene. J Virol (1988) 1.40

Identification of the E5 open reading frame of human papillomavirus type 16. J Virol (1988) 1.38

Genetic evidence that acute morphologic transformation, induction of cellular DNA synthesis, and focus formation are mediated by a single activity of the bovine papillomavirus E5 protein. Mol Cell Biol (1989) 1.37

Localization of bovine papillomavirus type 1 E5 protein to transformed basal keratinocytes and permissive differentiated cells in fibropapilloma tissue. Proc Natl Acad Sci U S A (1992) 1.35

Bovine papillomavirus E2 repressor mutant displays a high-copy-number phenotype and enhanced transforming activity. J Virol (1990) 1.32

Promoters and processing sites within the transforming region of bovine papillomavirus type 1. J Virol (1987) 1.32

Human papillomavirus type 1 produces redundant as well as polycistronic mRNAs in plantar warts. J Virol (1990) 1.31

Separation of the transcriptional activation and replication functions of the bovine papillomavirus-1 E2 protein. EMBO J (1992) 1.31

Multiple cis-active elements in the long control region of bovine papillomavirus type 1 (BPV-1). Nucleic Acids Res (1987) 1.27

An E1M--E2C fusion protein encoded by human papillomavirus type 11 is asequence-specific transcription repressor. J Virol (1991) 1.24

Characterization of the cis elements involved in basal and E2-transactivated expression of the bovine papillomavirus P2443 promoter. J Virol (1991) 1.23

Nucleotide sequences of cDNAs for human papillomavirus type 18 transcripts in HeLa cells. J Virol (1988) 1.22

Papillomavirus E6 oncoproteins. Virology (2013) 1.21

Differentiation-specific expression from the bovine papillomavirus type 1 P2443 and late promoters. J Virol (1993) 1.21

Identification of three transforming proteins encoded by cottontail rabbit papillomavirus. J Virol (1992) 1.20

Brd4-independent transcriptional repression function of the papillomavirus e2 proteins. J Virol (2007) 1.19

Transcriptional termination between bovine papillomavirus type 1 (BPV-1) early and late polyadenylation sites blocks late transcription in BPV-1-transformed cells. J Virol (1989) 1.18

A papillomavirus E2 phosphorylation mutant exhibits normal transient replication and transcription but is defective in transformation and plasmid retention. J Virol (1997) 1.17

Mutational analysis of open reading frame E4 of bovine papillomavirus type 1. J Virol (1987) 1.17

Regulation of early gene expression from the bovine papillomavirus genome in transiently transfected C127 cells. J Virol (1991) 1.16

Amino acids critical for the functions of the bovine papillomavirus type 1 E2 transactivator. J Virol (1996) 1.14

Transcriptional activation of several heterologous promoters by the E6 protein of human papillomavirus type 16. J Virol (1992) 1.14

The bovine papillomavirus distal "enhancer" is not cis essential for transformation or for plasmid maintenance. Mol Cell Biol (1985) 1.14

Direct interaction between nucleosome assembly protein 1 and the papillomavirus E2 proteins involved in activation of transcription. Mol Cell Biol (2004) 1.14

The bovine papillomavirus E5 oncogene can cooperate with ras: identification of p21 amino acids critical for transformation by c-rasH but not v-rasH. Mol Cell Biol (1991) 1.13

Levels of bovine papillomavirus RNA and protein expression correlate with variations in the tumorigenic phenotype of hamster cells. J Virol (1987) 1.13

Repression of bovine papillomavirus type 1 transcription by the E1 replication protein. J Virol (1993) 1.13

Sequence duplication and internal deletion in the integrated human papillomavirus type 16 genome cloned from a cervical carcinoma. J Virol (1988) 1.12

E2 of cottontail rabbit papillomavirus is a nuclear phosphoprotein translated from an mRNA encoding multiple open reading frames. J Virol (1988) 1.12

Glucocorticoid inhibition of transcription from episomal proopiomelanocortin gene promoter. Proc Natl Acad Sci U S A (1986) 1.12

Bovine papilloma virus encoded E2 protein activates lymphokine genes through DNA elements, distinct from the consensus motif, in the long control region of its own genome. EMBO J (1989) 1.10

Cooperative activation of human papillomavirus type 8 gene expression by the E2 protein and the cellular coactivator p300. J Virol (2002) 1.10

Induction of bovine papillomavirus E2 gene expression and early region transcription by cell growth arrest: correlation with viral DNA amplification and evidence for differential promoter induction. J Virol (1990) 1.08

Bovine papillomavirus type 1 E1 and simian virus 40 large T antigen share regions of sequence similarity required for multiple functions. J Virol (1997) 1.08

Regulation of human papillomavirus type 31 polyadenylation during the differentiation-dependent life cycle. J Virol (1999) 1.06

Articles cited by this

Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol (1975) 503.08

A new method for sequencing DNA. Proc Natl Acad Sci U S A (1977) 250.51

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I. J Mol Biol (1977) 205.11

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry (1979) 180.95

A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology (1973) 127.36

Studies on transformation of Escherichia coli with plasmids. J Mol Biol (1983) 116.81

Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene. Proc Natl Acad Sci U S A (1975) 77.46

In vivo sequence requirements of the SV40 early promotor region. Nature (1981) 25.00

A cDNA cloning vector that permits expression of cDNA inserts in mammalian cells. Mol Cell Biol (1983) 18.32

Possible role of flanking nucleotides in recognition of the AUG initiator codon by eukaryotic ribosomes. Nucleic Acids Res (1981) 18.27

The sequence 5'-AAUAAA-3'forms parts of the recognition site for polyadenylation of late SV40 mRNAs. Cell (1981) 12.26

Mouse cells transformed by bovine papillomavirus contain only extrachromosomal viral DNA sequences. Proc Natl Acad Sci U S A (1981) 9.27

The primary structure and genetic organization of the bovine papillomavirus type 1 genome. Nature (1982) 7.24

A quantitative in vitro focus assay for bovine papilloma virus. Virology (1980) 7.14

In vitro tumorigenic transformation by a defined sub-genomic fragment of bovine papilloma virus DNA. Nature (1980) 6.67

Identification of a second transforming region in bovine papillomavirus DNA. Proc Natl Acad Sci U S A (1984) 5.88

DNA sequence and genome organization of genital human papillomavirus type 6b. EMBO J (1983) 5.42

Characterization of the bovine papilloma virus plasmid maintenance sequences. Cell (1984) 5.01

BKV splice sequences based on analysis of preferred donor and acceptor sites. Nucleic Acids Res (1979) 4.86

Localization and analysis of bovine papillomavirus type 1 transforming functions. J Virol (1984) 4.77

Bovine papilloma virus deoxyribonucleic acid: a novel eucaryotic cloning vector. Mol Cell Biol (1981) 4.75

Bovine papilloma virus contains an activator of gene expression at the distal end of the early transcription unit. Mol Cell Biol (1983) 4.56

Virus-specific transcription in bovine papillomavirus-transformed mouse cells. Virology (1982) 4.52

New region of the simian virus 40 genome required for efficient viral transformation. Proc Natl Acad Sci U S A (1978) 4.24

The roles of the simian virus 40 tumor antigens in transformation of Chinese hamster lung cells. Cell (1979) 3.57

The transforming function of bovine papillomavirus DNA. Proc Natl Acad Sci U S A (1983) 3.19

Bovine papilloma virus transcription: polyadenylated RNA species and assessment of the direction of transcription. J Virol (1982) 3.04

Transcriptional organization of bovine papillomavirus type 1. J Virol (1983) 2.84

Comparative analysis of the human type 1a and bovine type 1 papillomavirus genomes. J Virol (1983) 2.69

Sequences of bovine papillomavirus type 1 DNA--functional and evolutionary implications. Nucleic Acids Res (1983) 1.68

Articles by these authors

High-efficiency transformation of mammalian cells by plasmid DNA. Mol Cell Biol (1987) 43.61

High-efficiency cloning of full-length cDNA. Mol Cell Biol (1982) 22.81

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell (1990) 20.60

Loop-mediated isothermal amplification of DNA. Nucleic Acids Res (2000) 19.30

A cDNA cloning vector that permits expression of cDNA inserts in mammalian cells. Mol Cell Biol (1983) 18.32

The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product. Science (1989) 16.54

Association of human papillomavirus types 16 and 18 E6 proteins with p53. Science (1990) 12.88

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell (1993) 12.41

Isolation and characterization of full-length cDNA clones for human alpha-, beta-, and gamma-actin mRNAs: skeletal but not cytoplasmic actins have an amino-terminal cysteine that is subsequently removed. Mol Cell Biol (1983) 11.06

High efficiency transformation of Escherichia coli with plasmids. Gene (1990) 10.65

Mouse cells transformed by bovine papillomavirus contain only extrachromosomal viral DNA sequences. Proc Natl Acad Sci U S A (1981) 9.27

The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes. J Virol (1989) 8.68

Structure and organization of the hepatitis C virus genome isolated from human carriers. J Virol (1991) 8.33

Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product. EMBO J (1989) 7.69

Transactivation of a bovine papilloma virus transcriptional regulatory element by the E2 gene product. Cell (1985) 7.56

The primary structure and genetic organization of the bovine papillomavirus type 1 genome. Nature (1982) 7.24

Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo. Mol Cell (1998) 7.01

Calcium phosphate-mediated gene transfer: a highly efficient transfection system for stably transforming cells with plasmid DNA. Biotechniques (1990) 6.90

In vitro tumorigenic transformation by a defined sub-genomic fragment of bovine papilloma virus DNA. Nature (1980) 6.67

Structural and transcriptional analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines. J Virol (1987) 6.65

The human papillomavirus type 16 E7 gene encodes transactivation and transformation functions similar to those of adenovirus E1A. Cell (1988) 6.28

Presence and expression of human papillomavirus sequences in human cervical carcinoma cell lines. Am J Pathol (1985) 6.18

A transcriptional repressor encoded by BPV-1 shares a common carboxy-terminal domain with the E2 transactivator. Cell (1987) 5.75

Isolation and characterization of a full-length expressible cDNA for human hypoxanthine phosphoribosyl transferase. Proc Natl Acad Sci U S A (1983) 5.50

Human IL-3 (multi-CSF): identification by expression cloning of a novel hematopoietic growth factor related to murine IL-3. Cell (1986) 5.43

A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18. EMBO J (1991) 5.39

A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase. Proc Natl Acad Sci U S A (1995) 5.37

A rapid method for detecting and mapping homology between heterologous DNAs. Evaluation of polyomavirus genomes. J Biol Chem (1979) 5.32

The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines. Proc Natl Acad Sci U S A (1991) 5.31

Transformation and replication in mouse cells of a bovine papillomavirus--pML2 plasmid vector that can be rescued in bacteria. Proc Natl Acad Sci U S A (1982) 5.22

High-efficiency cloning of full-length cDNA; construction and screening of cDNA expression libraries for mammalian cells. Methods Enzymol (1987) 5.08

High-frequency transformation method and library transducing vectors for cloning mammalian cDNAs by trans-complementation of Schizosaccharomyces pombe. Nucleic Acids Res (1990) 5.00

Trans-activation of the human immunodeficiency virus long terminal repeat sequence by DNA viruses. Proc Natl Acad Sci U S A (1986) 4.89

Localization and analysis of bovine papillomavirus type 1 transforming functions. J Virol (1984) 4.77

Bovine papilloma virus deoxyribonucleic acid: a novel eucaryotic cloning vector. Mol Cell Biol (1981) 4.75

Virus-specific transcription in bovine papillomavirus-transformed mouse cells. Virology (1982) 4.52

Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product. Proc Natl Acad Sci U S A (1992) 4.27

Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade. Science (1999) 4.21

Genetic programs of epithelial cell plasticity directed by transforming growth factor-beta. Proc Natl Acad Sci U S A (2001) 4.20

Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activity. Genes Dev (1998) 4.06

Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53. Mol Cell Biol (1993) 4.04

A kinase from fission yeast responsible for blocking mitosis in S phase. Nature (1995) 3.83

Differential promoter utilization by the bovine papillomavirus in transformed cells and productively infected wart tissues. EMBO J (1987) 3.77

Bovine papillomavirus transcriptional regulation: localization of the E2-responsive elements of the long control region. J Virol (1987) 3.66

Dissociation of transforming and trans-activation functions for bovine papillomavirus type 1. Nature (1986) 3.63

TGF-beta 1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains. Cell (1990) 3.55

In vivo ubiquitination and proteasome-mediated degradation of p53(1). Cancer Res (1996) 3.50

The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome. Mol Cell (2000) 3.39

The E5 transforming gene of bovine papillomavirus encodes a small, hydrophobic polypeptide. Science (1986) 3.37

Cloning of human papilloma virus genomic DNAs and analysis of homologous polynucleotide sequences. J Virol (1980) 3.34

p300/MDM2 complexes participate in MDM2-mediated p53 degradation. Mol Cell (1998) 3.27

The papillomavirus E2 regulatory proteins. J Biol Chem (1991) 3.27

Transcriptional trans-activation by the human papillomavirus type 16 E2 gene product. J Virol (1987) 3.24

Analysis of a human DNA excision repair gene involved in group A xeroderma pigmentosum and containing a zinc-finger domain. Nature (1990) 3.23

The carboxy-terminal domain shared by the bovine papillomavirus E2 transactivator and repressor proteins contains a specific DNA binding activity. EMBO J (1988) 3.20

E2 polypeptides encoded by bovine papillomavirus type 1 form dimers through the common carboxyl-terminal domain: transactivation is mediated by the conserved amino-terminal domain. Proc Natl Acad Sci U S A (1989) 3.18

Ubiquitination and degradation of the substrate recognition subunits of SCF ubiquitin-protein ligases. Mol Cell (1998) 3.12

Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53. Proc Natl Acad Sci U S A (1994) 3.12

The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein. EMBO J (1992) 2.97

Cdc25A is a novel phosphatase functioning early in the cell cycle. EMBO J (1994) 2.95

Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteins. Mol Cell Biol (1993) 2.91

Mutational analysis of cis elements involved in E2 modulation of human papillomavirus type 16 P97 and type 18 P105 promoters. J Virol (1990) 2.90

Transcriptional organization of bovine papillomavirus type 1. J Virol (1983) 2.84

Progressive squamous epithelial neoplasia in K14-human papillomavirus type 16 transgenic mice. J Virol (1994) 2.73

Comparative analysis of the human type 1a and bovine type 1 papillomavirus genomes. J Virol (1983) 2.69

Nucleotide sequence of 3-hydroxy-3-methyl-glutaryl coenzyme A reductase, a glycoprotein of endoplasmic reticulum. Nature (1984) 2.66

Bovine papillomavirus type 1 3' early region transformation and plasmid maintenance functions. J Virol (1986) 2.62

Human CSF-1: molecular cloning and expression of 4-kb cDNA encoding the human urinary protein. Science (1987) 2.50

Cellular proteins associated with simian virus 40 early gene products in newly infected cells. J Virol (1979) 2.44

Transient replication of human papillomavirus DNAs. J Virol (1992) 2.43

Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation. Mol Cell Biol (1997) 2.41

Wee1(+)-like gene in human cells. Nature (1991) 2.41

Bacteriophage lambda vector for transducing a cDNA clone library into mammalian cells. Mol Cell Biol (1985) 2.35

Disruption of either the E1 or the E2 regulatory gene of human papillomavirus type 16 increases viral immortalization capacity. Proc Natl Acad Sci U S A (1992) 2.30

Inhibition of cyclin D-CDK4/CDK6 activity is associated with an E2F-mediated induction of cyclin kinase inhibitor activity. Proc Natl Acad Sci U S A (1996) 2.30

The functional BPV-1 E2 trans-activating protein can act as a repressor by preventing formation of the initiation complex. Genes Dev (1991) 2.24

Structure-function analysis of the human papillomavirus type 16 E7 oncoprotein. J Virol (1992) 2.24

Physical interaction between specific E2 and Hect E3 enzymes determines functional cooperativity. J Biol Chem (1997) 2.23

A stable bovine papillomavirus hybrid plasmid that expresses a dominant selective trait. Mol Cell Biol (1983) 2.21

Comparison of Southern blot hybridization and polymerase chain reaction methods for the detection of human papillomavirus DNA. J Clin Microbiol (1991) 2.19

Physical map of the BK virus genome. J Virol (1975) 2.18

Fission yeast Eso1p is required for establishing sister chromatid cohesion during S phase. Mol Cell Biol (2000) 2.17

A new cdc gene required for S phase entry of Schizosaccharomyces pombe encodes a protein similar to the cdc 10+ and SWI4 gene products. EMBO J (1992) 2.14

Hormonal markers and hepatitis B virus-related hepatocellular carcinoma risk: a nested case-control study among men. J Natl Cancer Inst (2001) 2.11

Formation of infectious hybrid virions with gibbon ape leukemia virus and human T-cell leukemia virus retroviral envelope glycoproteins and the gag and pol proteins of Moloney murine leukemia virus. J Virol (1989) 2.11

Efficiency of binding the retinoblastoma protein correlates with the transforming capacity of the E7 oncoproteins of the human papillomaviruses. Proc Natl Acad Sci U S A (1992) 2.10

Id-related genes encoding helix-loop-helix proteins are required for G1 progression and are repressed in senescent human fibroblasts. J Biol Chem (1994) 2.09

The role of E6AP in the regulation of p53 protein levels in human papillomavirus (HPV)-positive and HPV-negative cells. J Biol Chem (1998) 2.07

Chronic estrogen-induced cervical and vaginal squamous carcinogenesis in human papillomavirus type 16 transgenic mice. Proc Natl Acad Sci U S A (1996) 2.06

Structure and expression of a human oxytocin receptor. Nature (1992) 2.06

Suppression of cellular proliferation by the papillomavirus E2 protein. J Virol (1995) 2.05

Production of nonstructural proteins of hepatitis C virus requires a putative viral protease encoded by NS3. Virology (1994) 2.04

An additional homolog of the fission yeast cdc25+ gene occurs in humans and is highly expressed in some cancer cells. New Biol (1991) 2.04

Identification of HHR23A as a substrate for E6-associated protein-mediated ubiquitination. J Biol Chem (1999) 2.02

Functional analysis of E2-mediated repression of the HPV18 P105 promoter. New Biol (1991) 2.02

Pregnant, vomiting, and going blind. Lancet (1998) 2.00