Published in Nucleic Acids Res on August 26, 1986
XIST RNA paints the inactive X chromosome at interphase: evidence for a novel RNA involved in nuclear/chromosome structure. J Cell Biol (1996) 5.51
Role of RNase H in hybrid-arrested translation by antisense oligonucleotides. Proc Natl Acad Sci U S A (1988) 2.98
Inhibition of human immunodeficiency virus replication by antisense oligodeoxynucleotides. Proc Natl Acad Sci U S A (1988) 2.85
Molecular cloning and characterization of the mRNA for cyclin from sea urchin eggs. EMBO J (1987) 2.71
Enzymatic amplification of translation inhibition of rabbit beta-globin mRNA mediated by anti-messenger oligodeoxynucleotides covalently linked to intercalating agents. Nucleic Acids Res (1987) 2.41
Selective elimination of mRNAs in vivo: complementary oligodeoxynucleotides promote RNA degradation by an RNase H-like activity. Proc Natl Acad Sci U S A (1987) 2.23
Hepatitis B virus persistence after recovery from acute viral hepatitis. J Clin Invest (1994) 2.10
Comparative hybrid arrest by tandem antisense oligodeoxyribonucleotides or oligodeoxyribonucleoside methylphosphonates in a cell-free system. Nucleic Acids Res (1988) 2.10
Comparative inhibition of chloramphenicol acetyltransferase gene expression by antisense oligonucleotide analogues having alkyl phosphotriester, methylphosphonate and phosphorothioate linkages. Nucleic Acids Res (1987) 2.06
Comparative inhibition of rabbit globin mRNA translation by modified antisense oligodeoxynucleotides. Nucleic Acids Res (1989) 1.98
Molecular cloning and chromosomal localization of the human T-cell receptor zeta chain: distinction from the molecular CD3 complex. Proc Natl Acad Sci U S A (1988) 1.95
The stability, toxicity and effectiveness of unmodified and phosphorothioate antisense oligodeoxynucleotides in Xenopus oocytes and embryos. Nucleic Acids Res (1990) 1.93
Efficient initiation of mammalian mRNA translation at a CUG codon. Nucleic Acids Res (1989) 1.90
Scanning independent ribosomal initiation of the Sendai virus X protein. EMBO J (1988) 1.77
Antisense oligonucleotide-directed cleavage of mRNA in Xenopus oocytes and eggs. EMBO J (1988) 1.75
Silencing disease genes in the laboratory and the clinic. J Pathol (2011) 1.72
Molecular evidence that insecticide resistance in peach-potato aphids (Myzus persicae Sulz.) results from amplification of an esterase gene. Biochem J (1988) 1.68
A tripartite structure of the signals that determine protein insertion into the endoplasmic reticulum membrane. J Cell Biol (1989) 1.61
Scanning independent ribosomal initiation of the Sendai virus Y proteins in vitro and in vivo. EMBO J (1989) 1.54
alpha-DNA. VI: Comparative study of alpha- and beta-anomeric oligodeoxyribonucleotides in hybridization to mRNA and in cell free translation inhibition. Nucleic Acids Res (1987) 1.53
Site-specific excision from RNA by RNase H and mixed-phosphate-backbone oligodeoxynucleotides. Proc Natl Acad Sci U S A (1990) 1.50
Inhibition of simian virus 40 DNA replication in CV-1 cells by an oligodeoxynucleotide covalently linked to an intercalating agent. Nucleic Acids Res (1990) 1.42
Inhibition of translation initiation by antisense oligonucleotides via an RNase-H independent mechanism. Nucleic Acids Res (1991) 1.29
A rapid in vitro method for obtaining RNA accessibility patterns for complementary DNA probes: correlation with an intracellular pattern and known RNA structures. Nucleic Acids Res (1997) 1.26
Xenopus oocyte maturation does not require new cyclin synthesis. J Cell Biol (1991) 1.26
Number and distribution of methylphosphonate linkages in oligodeoxynucleotides affect exo- and endonuclease sensitivity and ability to form RNase H substrates. Nucleic Acids Res (1989) 1.26
Mapping of monoclonal antibodies to the Sendai virus P protein and the location of its phosphates. J Virol (1988) 1.25
Target-specific arrest of mRNA translation by antisense 2'-O-alkyloligoribonucleotides. Nucleic Acids Res (1994) 1.24
Short modified antisense oligonucleotides directed against Ha-ras point mutation induce selective cleavage of the mRNA and inhibit T24 cells proliferation. EMBO J (1991) 1.22
Targeting RNA for degradation with a (2'-5')oligoadenylate-antisense chimera. Proc Natl Acad Sci U S A (1993) 1.19
Predicting antisense oligonucleotide inhibitory efficacy: a computational approach using histograms and thermodynamic indices. Nucleic Acids Res (1992) 1.17
Targeted inhibition of gene expression of pancreatitis-associated proteins exacerbates the severity of acute pancreatitis in rats. Scand J Gastroenterol (2004) 1.15
Antisense oligonucleotides selected by hybridisation to scanning arrays are effective reagents in vivo. Nucleic Acids Res (2001) 1.12
An extended RNA/RNA duplex structure within the coding region of mRNA does not block translational elongation. Nucleic Acids Res (1988) 1.08
Antisense phosphorothioate oligonucleotides: selective killing of the intracellular parasite Leishmania amazonensis. Proc Natl Acad Sci U S A (1994) 1.07
2'-fluoro-4'-thioarabino-modified oligonucleotides: conformational switches linked to siRNA activity. Nucleic Acids Res (2007) 1.03
Developmental expression of the protein product of Vg1, a localized maternal mRNA in the frog Xenopus laevis. EMBO J (1989) 1.00
Purification and characterization of human ribonuclease HII. Nucleic Acids Res (1994) 0.99
Effect of downregulation of germline transcripts on immunoglobulin A isotype differentiation. J Exp Med (1993) 0.97
Effects of oligo sequence and chemistry on the efficiency of oligodeoxyribonucleotide-mediated mRNA cleavage. Nucleic Acids Res (1990) 0.95
Molecular requirements for degradation of a modified sense RNA strand by Escherichia coli ribonuclease H1. Nucleic Acids Res (2002) 0.94
Complementary oligodeoxynucleotide mediated inhibition of tobacco mosaic virus RNA translation in vitro. Nucleic Acids Res (1988) 0.92
Effect of RNA secondary structure and modified bases on the inhibition of trypanosomatid protein synthesis in cell free extracts by antisense oligodeoxynucleotides. Nucleic Acids Res (1990) 0.92
Functional mapping of the genome of the B19 (human) parvovirus by in vitro translation after negative hybrid selection. J Virol (1988) 0.91
Alpha-DNA.IX: Parallel annealing of alpha-anomeric oligodeoxyribonucleotides to natural mRNA is required for interference in RNase H mediated hydrolysis and reverse transcription. Nucleic Acids Res (1989) 0.89
mRNA fusion constructs serve in a general cell-based assay to profile oligonucleotide activity. Nucleic Acids Res (2003) 0.87
Therapeutic antisense oligonucleotides against cancer: hurdling to the clinic. Front Chem (2014) 0.84
Phosphoroselenoate oligodeoxynucleotides: synthesis, physico-chemical characterization, anti-sense inhibitory properties and anti-HIV activity. Nucleic Acids Res (1989) 0.83
Hybridization arrest of cell-free translation of the malarial dihydrofolate reductase/thymidylate synthase mRNA by anti-sense oligodeoxyribonucleotides. Nucleic Acids Res (1991) 0.82
A more efficient and specific strategy in the ablation of mRNA in Xenopus laevis using mixtures of antisense oligos. Nucleic Acids Res (1993) 0.82
Rational design of point mutation-selective antisense DNA targeted to codon 12 of Ha-ras mRNA in human cells. Nucleic Acids Res (1995) 0.80
Fast and accurate determination of sites along the FUT2 in vitro transcript that are accessible to antisense oligonucleotides by application of secondary structure predictions and RNase H in combination with MALDI-TOF mass spectrometry. Nucleic Acids Res (2003) 0.79
Antisense morpholino targeting just upstream from a poly(A) tail junction of maternal mRNA removes the tail and inhibits translation. Nucleic Acids Res (2012) 0.79
Selective inhibition of cell-free translation by oligonucleotides targeted to a mRNA hairpin structure. Nucleic Acids Res (1998) 0.79
Synthetic antisense oligodeoxynucleotides to transiently suppress different nucleus- and chloroplast-encoded proteins of higher plant chloroplasts. Plant Physiol (2011) 0.78
5'-O-Methylphosphonate nucleic acids--new modified DNAs that increase the Escherichia coli RNase H cleavage rate of hybrid duplexes. Nucleic Acids Res (2014) 0.77
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Novel antisense oligonucleotides containing hydroxamate linkages: targeted iron-triggered chemical nucleases. Biometals (2009) 0.75
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Cyclin: a protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division. Cell (1983) 9.90
Nucleotide sequence of tobacco mosaic virus RNA. Proc Natl Acad Sci U S A (1982) 7.61
Structural gene identification and mapping by DNA-mRNA hybrid-arrested cell-free translation. Proc Natl Acad Sci U S A (1977) 7.46
Preparation and use of nuclease-treated rabbit reticulocyte lysates for the translation of eukaryotic messenger RNA. Methods Enzymol (1983) 7.38
Multiple factors including the small nuclear ribonucleoproteins U1 and U2 are necessary for pre-mRNA splicing in vitro. Cell (1985) 6.85
The 5' terminus of the RNA moiety of U1 small nuclear ribonucleoprotein particles is required for the splicing of messenger RNA precursors. Cell (1984) 6.25
Site specific enzymatic cleavage of RNA. Nucleic Acids Res (1979) 5.15
Injected anti-sense RNAs specifically block messenger RNA translation in vivo. Proc Natl Acad Sci U S A (1985) 5.09
Cell-free translation of messenger RNA in a wheat germ system. Methods Enzymol (1983) 4.52
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Inhibition of rabbit globin mRNA translation by sequence-specific oligodeoxyribonucleotides. Biochemistry (1985) 2.39
Quantitative hybridization-arrest of mRNA in Xenopus oocytes using single-stranded complementary DNA or oligonucleotide probes. Nucleic Acids Res (1985) 2.38
Translation arrest by oligodeoxynucleotides complementary to mRNA coding sequences yields polypeptides of predetermined length. Nucleic Acids Res (1986) 2.21
Translation of mRNA injected into Xenopus oocytes is specifically inhibited by antisense RNA. J Cell Biol (1985) 2.05
Purification and characterization of murine retroviral reverse transcriptase expressed in Escherichia coli. J Biol Chem (1985) 2.02
Methods utilizing cell-free protein-synthesizing systems for the identification of recombinant DNA molecules. Methods Enzymol (1983) 1.94
Translationally associated helix-destabilizing activity in rabbit reticulocyte lysate. J Biol Chem (1984) 1.85
The small subunit of ribonucleotide reductase is encoded by one of the most abundant translationally regulated maternal RNAs in clam and sea urchin eggs. J Cell Biol (1985) 1.68
Translational properties of rabbit globin mRNA after specific removal of poly(A) with ribonuclease H. Proc Natl Acad Sci U S A (1974) 1.41
The use of single-stranded phage DNAs in hybrid arrest and release translation. Anal Biochem (1982) 1.19
Ribonuclease H activity in germinal vesicles of oocytes from Rana pipiens. Exp Cell Res (1974) 0.87
Methods for cDNA cloning and sequencing tobacco mosaic virus RNA. Gene (1984) 0.86
Cyclin: a protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division. Cell (1983) 9.90
A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins. Cell (1994) 8.52
Preparation and use of nuclease-treated rabbit reticulocyte lysates for the translation of eukaryotic messenger RNA. Methods Enzymol (1983) 7.38
Phosphorylation of initiation factor elF-2 and the control of reticulocyte protein synthesis. Cell (1977) 6.22
Cut2 proteolysis required for sister-chromatid seperation in fission yeast. Nature (1996) 4.86
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Cyclin is a component of maturation-promoting factor from Xenopus. Cell (1990) 4.70
Translation of cyclin mRNA is necessary for extracts of activated xenopus eggs to enter mitosis. Cell (1989) 4.56
The A- and B-type cyclin associated cdc2 kinases in Xenopus turn on and off at different times in the cell cycle. EMBO J (1990) 4.25
Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations. Hum Mol Genet (2005) 4.12
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Messenger RNA for the coat protein of tobacco mosaic virus. Nature (1976) 3.85
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Cyclin A and the retinoblastoma gene product complex with a common transcription factor. Nature (1991) 3.15
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The cdc2-related protein p40MO15 is the catalytic subunit of a protein kinase that can activate p33cdk2 and p34cdc2. EMBO J (1993) 3.03
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