Published in EMBO J on September 15, 1999
Rad23 promotes the targeting of proteolytic substrates to the proteasome. Mol Cell Biol (2002) 3.01
Budding yeast Dsk2p is a polyubiquitin-binding protein that can interact with the proteasome. Proc Natl Acad Sci U S A (2002) 2.63
Identification of ubiquilin, a novel presenilin interactor that increases presenilin protein accumulation. J Cell Biol (2000) 2.11
Nonperiodic activity of the human anaphase-promoting complex-Cdh1 ubiquitin ligase results in continuous DNA synthesis uncoupled from mitosis. Mol Cell Biol (2000) 1.74
Interaction with a ubiquitin-like protein enhances the ubiquitination and degradation of hepatitis C virus RNA-dependent RNA polymerase. J Virol (2003) 1.32
The DNA damage-inducible UbL-UbA protein Ddi1 participates in Mec1-mediated degradation of Ho endonuclease. Mol Cell Biol (2005) 1.30
Kaposi's sarcoma-associated herpesvirus K7 protein targets a ubiquitin-like/ubiquitin-associated domain-containing protein to promote protein degradation. Mol Cell Biol (2004) 1.10
Viral cyclin-cyclin-dependent kinase 6 complexes initiate nuclear DNA replication. Mol Cell Biol (2001) 1.09
The ubiquitin-related protein PLIC-1 regulates heterotrimeric G protein function through association with Gbetagamma. J Cell Biol (2003) 1.09
The ubiquilin gene family: evolutionary patterns and functional insights. BMC Evol Biol (2014) 1.08
The RAD23 family provides an essential connection between the 26S proteasome and ubiquitylated proteins in Arabidopsis. Plant Cell (2010) 1.03
Alzheimer's disease-associated ubiquilin-1 regulates presenilin-1 accumulation and aggresome formation. Traffic (2011) 1.02
Dimerization of ubiquilin is dependent upon the central region of the protein: evidence that the monomer, but not the dimer, is involved in binding presenilins. Biochem J (2006) 0.97
Coordination of centrosome homeostasis and DNA repair is intact in MCF-7 and disrupted in MDA-MB 231 breast cancer cells. Cancer Res (2010) 0.89
Studies of the role of ubiquitination in the interaction of ubiquilin with the loop and carboxyl terminal regions of presenilin-2. Biochemistry (2007) 0.85
The TREX1 C-terminal region controls cellular localization through ubiquitination. J Biol Chem (2013) 0.83
Involvement of rhp23, a Schizosaccharomyces pombe homolog of the human HHR23A and Saccharomyces cerevisiae RAD23 nucleotide excision repair genes, in cell cycle control and protein ubiquitination. Nucleic Acids Res (2002) 0.82
Cyclin: a protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division. Cell (1983) 9.90
Engineered GFP as a vital reporter in plants. Curr Biol (1996) 9.03
A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins. Cell (1994) 8.52
Preparation and use of nuclease-treated rabbit reticulocyte lysates for the translation of eukaryotic messenger RNA. Methods Enzymol (1983) 7.38
Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle. Science (1992) 6.40
Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing. Environ Mol Mutagen (2000) 6.24
Phosphorylation of initiation factor elF-2 and the control of reticulocyte protein synthesis. Cell (1977) 6.22
Cut2 proteolysis required for sister-chromatid seperation in fission yeast. Nature (1996) 4.86
Recombinant leptin for weight loss in obese and lean adults: a randomized, controlled, dose-escalation trial. JAMA (1999) 4.71
Cyclin is a component of maturation-promoting factor from Xenopus. Cell (1990) 4.70
Translation of cyclin mRNA is necessary for extracts of activated xenopus eggs to enter mitosis. Cell (1989) 4.56
The Cdt1 protein is required to license DNA for replication in fission yeast. Nature (2000) 4.46
The A- and B-type cyclin associated cdc2 kinases in Xenopus turn on and off at different times in the cell cycle. EMBO J (1990) 4.25
The RCC1 protein, a regulator for the onset of chromosome condensation locates in the nucleus and binds to DNA. J Cell Biol (1989) 4.13
Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations. Hum Mol Genet (2005) 4.12
Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint. J Cell Biol (2001) 3.86
Messenger RNA for the coat protein of tobacco mosaic virus. Nature (1976) 3.85
Premature of chromosome condensation in a ts DNA- mutant of BHK cells. Cell (1978) 3.55
Control of globin synthesis: the role of heme. J Mol Biol (1972) 3.47
Rearrangement of the MLL gene in acute lymphoblastic and acute myeloid leukemias with 11q23 chromosomal translocations. N Engl J Med (1993) 3.37
Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B. J Biol Chem (2000) 3.17
Cyclin A and the retinoblastoma gene product complex with a common transcription factor. Nature (1991) 3.15
ATP-linked calcium transport in cells and membrane vesicles of Streptococcus faecalis. J Biol Chem (1978) 3.14
The proteolysis of mitotic cyclins in mammalian cells persists from the end of mitosis until the onset of S phase. EMBO J (1996) 3.12
Bone marrow contributes to renal parenchymal turnover and regeneration. J Pathol (2001) 3.04
The cdc2-related protein p40MO15 is the catalytic subunit of a protein kinase that can activate p33cdk2 and p34cdc2. EMBO J (1993) 3.03
Double-stranded poliovirus RNA inhibits initiation of protein synthesis by reticulocyte lysates. Proc Natl Acad Sci U S A (1971) 2.99
The use of single-stranded DNA and RNase H to promote quantitative 'hybrid arrest of translation' of mRNA/DNA hybrids in reticulocyte lysate cell-free translations. Nucleic Acids Res (1986) 2.97
The 3'-untranslated regions of c-mos and cyclin mRNAs stimulate translation by regulating cytoplasmic polyadenylation. Genes Dev (1994) 2.95
Triggering of cyclin degradation in interphase extracts of amphibian eggs by cdc2 kinase. Nature (1990) 2.89
Non-invasive quantitative detection and applications of non-toxic, S65T-type green fluorescent protein in living plants. Plant J (1999) 2.88
Loss of RCC1, a nuclear DNA-binding protein, uncouples the completion of DNA replication from the activation of cdc2 protein kinase and mitosis. EMBO J (1991) 2.86
The characteristics of inhibition of protein synthesis by double-stranded ribonucleic acid in reticulocyte lysates. J Biol Chem (1975) 2.84
A single-point mutation in HCF causes temperature-sensitive cell-cycle arrest and disrupts VP16 function. Genes Dev (1997) 2.84
The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis. J Exp Med (1997) 2.83
Initiation of protein synthesis: evidence for messenger RNA-independent binding of methionyl-transfer RNA to the 40 S ribosomal subunit. J Mol Biol (1973) 2.80
Cyclin is a component of the sea urchin egg M-phase specific histone H1 kinase. EMBO J (1989) 2.75
A proton-translocating ATPase regulates pH of the bacterial cytoplasm. J Biol Chem (1985) 2.71
Molecular cloning and characterization of the mRNA for cyclin from sea urchin eggs. EMBO J (1987) 2.71
A brain-specific activator of cyclin-dependent kinase 5. Nature (1994) 2.71
Psychometric validation of an overactive bladder symptom and health-related quality of life questionnaire: the OAB-q. Qual Life Res (2002) 2.66
Expression of stromal cell-derived factor 1 and CXCR4 ligand receptor system in pancreatic cancer: a possible role for tumor progression. Clin Cancer Res (2000) 2.61
Regulation of the cytoplasmic pH in Streptococcus faecalis. J Biol Chem (1982) 2.61
Chemical and immunological characterization of the extracellular galactomannan of Aspergillus fumigatus. Infect Immun (1994) 2.60
Self-organization of microtubule asters induced in Xenopus egg extracts by GTP-bound Ran. Science (1999) 2.59
RagA is a functional homologue of S. cerevisiae Gtr1p involved in the Ran/Gsp1-GTPase pathway. J Cell Sci (1998) 2.58
Selective translation of mRNA controls the pattern of protein synthesis during early development of the surf clam, Spisula solidissima. Cell (1980) 2.49
Cloning of ELL, a gene that fuses to MLL in a t(11;19)(q23;p13.1) in acute myeloid leukemia. Proc Natl Acad Sci U S A (1994) 2.44
Control of protein synthesis in reticulocyte lysates by haemin. Nat New Biol (1973) 2.39
The human licensing factor for DNA replication Cdt1 accumulates in G1 and is destabilized after initiation of S-phase. J Biol Chem (2001) 2.38
Estimation of polyamine binding to macromolecules and ATP in bovine lymphocytes and rat liver. J Biol Chem (1991) 2.36
Cyclin synthesis, modification and destruction during meiotic maturation of the starfish oocyte. Dev Biol (1987) 2.35
The human CCG1 gene, essential for progression of the G1 phase, encodes a 210-kilodalton nuclear DNA-binding protein. Mol Cell Biol (1991) 2.30
The crystal structure of cyclin A. Structure (1995) 2.28
Green-fluorescent protein as a new vital marker in plant cells. Plant J (1995) 2.28
Unique morphology of the human eye. Nature (1997) 2.27
Rapid acquisition of multicellular drug resistance after a single exposure of mammary tumor cells to antitumor alkylating agents. J Natl Cancer Inst (1994) 2.25
DNA methylation as a mechanism of transcriptional regulation in nonphotosynthetic plastids in plant cells. Proc Natl Acad Sci U S A (1988) 2.19
Simultaneous detection of multiple green fluorescent proteins in live cells by fluorescence lifetime imaging microscopy. Curr Biol (1999) 2.18
The role of proteolysis in cell cycle progression in Schizosaccharomyces pombe. EMBO J (1996) 2.13
GTP hydrolysis by Ran occurs at the nuclear pore complex in an early step of protein import. J Cell Biol (1995) 2.12
The c-mos proto-oncogene protein kinase turns on and maintains the activity of MAP kinase, but not MPF, in cell-free extracts of Xenopus oocytes and eggs. EMBO J (1993) 2.10
Immunohistochemical characterization of glomerular IgA deposits in IgA nephropathy. Clin Nephrol (1990) 2.09
On the translational control of suicide in red cell development. Trends Biochem Sci (1989) 2.09
The number of ribosomal RNA genes in Mycoplasma capricolum. Mol Gen Genet (1981) 2.08
RCC1, a regulator of mitosis, is essential for DNA replication. Mol Cell Biol (1992) 2.08
VP16 targets an amino-terminal domain of HCF involved in cell cycle progression. Mol Cell Biol (1997) 2.07
On the synthesis and destruction of A- and B-type cyclins during oogenesis and meiotic maturation in Xenopus laevis. J Cell Biol (1991) 2.06
A post-ribosomal supernatant from activated Xenopus eggs that displays post-translationally regulated oscillation of its cdc2+ mitotic kinase activity. EMBO J (1989) 2.05
High expression of Survivin, mapped to 17q25, is significantly associated with poor prognostic factors and promotes cell survival in human neuroblastoma. Oncogene (2000) 2.04
Streptococcal cytoplasmic pH is regulated by changes in amount and activity of a proton-translocating ATPase. J Biol Chem (1986) 2.03
Copper proteins and oxygen. Correlations between structure and function of the copper oxidases. J Gen Physiol (1965) 2.02
Lysenin, a novel sphingomyelin-specific binding protein. J Biol Chem (1998) 2.02
Inhibition of neurotransmission by peptides containing the synaptic protein interaction site of N-type Ca2+ channels. Neuron (1996) 1.98
Structure of a Ran-binding domain complexed with Ran bound to a GTP analogue: implications for nuclear transport. Nature (1999) 1.97
Cip1 blocks the initiation of DNA replication in Xenopus extracts by inhibition of cyclin-dependent kinases. Curr Biol (1994) 1.95
Carbenoxolone in the treatment of duodenal ulcer. Practitioner (1967) 1.95
Active efflux of daunorubicin and adriamycin in sensitive and resistant sublines of P388 leukemia. Cancer Res (1979) 1.93
Field test of quantum key distribution in the Tokyo QKD Network. Opt Express (2011) 1.89
Molecular cloning of a human cDNA encoding a novel protein, DAD1, whose defect causes apoptotic cell death in hamster BHK21 cells. Mol Cell Biol (1993) 1.88
Amplification of the Streptococcus faecalis proton-translocating ATPase by a decrease in cytoplasmic pH. J Bacteriol (1984) 1.87
Ubc9p and the conjugation of SUMO-1 to RanGAP1 and RanBP2. Curr Biol (1998) 1.86
Identification of the domains in cyclin A required for binding to, and activation of, p34cdc2 and p32cdk2 protein kinase subunits. Mol Biol Cell (1992) 1.85
The incidence of simple renal cyst by computed tomography. Clin Radiol (1983) 1.82
Cyclin B2-null mice develop normally and are fertile whereas cyclin B1-null mice die in utero. Proc Natl Acad Sci U S A (1998) 1.82
Molecular cloning of a human gene that regulates chromosome condensation and is essential for cell proliferation. Mol Cell Biol (1986) 1.80
Consistent intergenic splicing and production of multiple transcripts between AML1 at 21q22 and unrelated genes at 3q26 in (3;21)(q26;q22) translocations. Proc Natl Acad Sci U S A (1994) 1.78
When overexpressed, a novel centrosomal protein, RanBPM, causes ectopic microtubule nucleation similar to gamma-tubulin. J Cell Biol (1998) 1.78
A mutant form of the Ran/TC4 protein disrupts nuclear function in Xenopus laevis egg extracts by inhibiting the RCC1 protein, a regulator of chromosome condensation. EMBO J (1994) 1.76
The effect of cyclic AMP and related compounds on the control of protein synthesis in reticulocyte lysates. Biochem Biophys Res Commun (1974) 1.74
Pressure-dependent metallic and superconducting phases in a germanium artificial metal. Phys Rev Lett (2009) 1.73
Direct evidence of neuron impairment by oral infection with verotoxin-producing Escherichia coli O157:H- in mitomycin-treated mice. Infect Immun (1994) 1.72
Cytoplasm from poliovirus-infected HeLa cells inhibits cell-free haemoglobin synthesis. Nat New Biol (1971) 1.72
Actions of noradrenaline and acetylcholine on sympathetic ganglion cells. J Physiol (1970) 1.72
Genetic localization of a new locus for recessive familial spastic paraparesis to 15q13-15. Neurology (1999) 1.72
The synthesis of protein(s) for chromosome condensation may be regulated by a post-transcriptional mechanism. J Cell Physiol (1981) 1.71
Susceptibility of hepatitis B virus to disinfectants or heat. J Clin Microbiol (1984) 1.70