Structure, expression, and chromosomal location of the human c-fgr gene.

PubWeight™: 1.47‹?› | Rank: Top 5%

🔗 View Article (PMC 367540)

Published in Mol Cell Biol on February 01, 1986

Authors

M Nishizawa, K Semba, M C Yoshida, T Yamamoto, M Sasaki, K Toyoshima

Articles citing this

yes-related protooncogene, syn, belongs to the protein-tyrosine kinase family. Proc Natl Acad Sci U S A (1986) 3.19

The level of c-fgr RNA is increased by EBNA-2, an Epstein-Barr virus gene required for B-cell immortalization. J Virol (1990) 2.75

Activation of the oncogenic potential of the avian cellular src protein by specific structural alteration of the carboxy terminus. EMBO J (1987) 2.67

Mutation of a site of tyrosine phosphorylation in the lymphocyte-specific tyrosine protein kinase, p56lck, reveals its oncogenic potential in fibroblasts. Proc Natl Acad Sci U S A (1988) 2.60

Novel protein-tyrosine kinase gene (hck) preferentially expressed in cells of hematopoietic origin. Mol Cell Biol (1987) 2.52

The yes-related cellular gene lyn encodes a possible tyrosine kinase similar to p56lck. Mol Cell Biol (1987) 2.44

Identification and characterization of p59fyn (a src-like protein tyrosine kinase) in normal and polyoma virus transformed cells. EMBO J (1988) 2.28

Characterization of cDNA clones for the human c-yes gene. Mol Cell Biol (1987) 2.11

Do exons code for structural or functional units in proteins? Proc Natl Acad Sci U S A (1988) 2.06

Structure of the murine lck gene and its rearrangement in a murine lymphoma cell line. Mol Cell Biol (1988) 1.66

The 5' splice site: phylogenetic evolution and variable geometry of association with U1RNA. Nucleic Acids Res (1989) 1.60

Primary structure of the human fgr proto-oncogene product p55c-fgr. Mol Cell Biol (1988) 1.48

Localization of a lymphocyte-specific protein tyrosine kinase gene (lck) at a site of frequent chromosomal abnormalities in human lymphomas. Proc Natl Acad Sci U S A (1986) 1.42

A mutation in v-src that removes a single conserved residue in the SH-2 domain of pp60v-src restricts transformation in a host-dependent manner. J Virol (1989) 1.40

Cellular proteins homologous to the viral yes gene product. Mol Cell Biol (1986) 1.40

The carboxy terminus of pp60c-src is a regulatory domain and is involved in complex formation with the middle-T antigen of polyomavirus. Mol Cell Biol (1988) 1.26

Two additional protein-tyrosine kinases expressed in human lung: fourth member of the fibroblast growth factor receptor family and an intracellular protein-tyrosine kinase. Proc Natl Acad Sci U S A (1991) 1.20

Oncogenic activation of the Lck protein accompanies translocation of the LCK gene in the human HSB2 T-cell leukemia. Mol Cell Biol (1994) 1.19

Rapid and efficient purification of Src homology 2 domain-containing proteins: Fyn, Csk and phosphatidylinositol 3-kinase p85. Biochem J (1994) 1.10

Evolution, expression, and chromosomal location of a novel receptor tyrosine kinase gene, eph. Mol Cell Biol (1988) 1.07

Differential expression and regulation of the c-src and c-fgr protooncogenes in myelomonocytic cells. Proc Natl Acad Sci U S A (1987) 1.05

Natural biology of polyomavirus middle T antigen. Microbiol Mol Biol Rev (2001) 1.02

The carboxy-terminal sequence of p56lck can regulate p60c-src. Mol Cell Biol (1988) 1.01

Transformation of chicken embryo fibroblast cells by avian retroviruses containing the human Fyn gene and its mutated genes. Mol Cell Biol (1990) 0.89

Structure and expression of c-fgr protooncogene mRNA in Epstein-Barr virus converted cell lines. Br J Cancer (1988) 0.83

Articles cited by this

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry (1979) 180.95

New M13 vectors for cloning. Methods Enzymol (1983) 90.74

A membrane-filter technique for the detection of complementary DNA. Biochem Biophys Res Commun (1966) 71.25

Construction of improved M13 vectors using oligodeoxynucleotide-directed mutagenesis. Gene (1983) 44.52

A catalogue of splice junction sequences. Nucleic Acids Res (1982) 39.41

RNA molecular weight determinations by gel electrophoresis under denaturing conditions, a critical reexamination. Biochemistry (1977) 38.82

The isolation of structural genes from libraries of eucaryotic DNA. Cell (1978) 37.13

The structure and evolution of the human beta-globin gene family. Cell (1980) 21.24

Cellular oncogenes and retroviruses. Annu Rev Biochem (1983) 10.65

Structure and sequence of the cellular gene homologous to the RSV src gene and the mechanism for generating the transforming virus. Cell (1983) 7.37

The molecular genetics of human hemoglobins. Annu Rev Genet (1980) 4.67

Avian sarcoma virus Y73 genome sequence and structural similarity of its transforming gene product to that of Rous sarcoma virus. Nature (1982) 4.33

Identification of transforming gene in two human sarcoma cell lines as a new member of the ras gene family located on chromosome 1. Nature (1983) 3.86

Characterization of Y73, an avian sarcoma virus: a unique transforming gene and its product, a phosphopolyprotein with protein kinase activity. Proc Natl Acad Sci U S A (1980) 3.58

Isolation and preliminary characterization of the transforming gene of a human neuroblastoma cell line. Proc Natl Acad Sci U S A (1983) 3.52

DNA sequence of the viral and cellular src gene of chickens. 1. Complete nucleotide sequence of an EcoRI fragment of recovered avian sarcoma virus which codes for gp37 and pp60src. J Virol (1982) 3.35

Gene product of v-fgr onc: hybrid protein containing a portion of actin and a tyrosine-specific protein kinase. Science (1984) 3.06

The mouse c-abl locus: molecular cloning and characterization. Cell (1984) 2.33

Structure and biological activity of human homologs of the raf/mil oncogene. Mol Cell Biol (1985) 2.19

Evidence for two distinct c-src loci on human chromosomes 1 and 20. Nature (1984) 1.91

Chromosome abnormalities in poorly differentiated lymphocytic lymphoma. Cancer Res (1979) 1.69

Nucleotide sequences of the Drosophila src and abl homologs: conservation and variability in the src family oncogenes. Cell (1983) 1.65

Homologous cell-derived oncogenes in avian carcinoma virus MH2 and murine sarcoma virus 3611. Nature (1984) 1.56

Chromosomal assignment of a family of human oncogenes. Proc Natl Acad Sci U S A (1983) 1.53

Location of the c-yes gene on the human chromosome and its expression in various tissues. Science (1985) 1.46

Human cellular src gene: nucleotide sequence and derived amino acid sequence of the region coding for the carboxy-terminal two-thirds of pp60c-src. Mol Cell Biol (1985) 1.46

Proliferation and differentiation of lymphoid cells: studies with human lymphoid cell lines and immunoglobulin synthesis. Ann N Y Acad Sci (1971) 1.43

Drosophila melanogaster DNA clones homologous to vertebrate oncogenes: evidence for a common ancestor to the src and abl cellular genes. Cell (1983) 1.43

Isolation of duplicated human c-src genes located on chromosomes 1 and 20. Mol Cell Biol (1985) 1.39

Three loci related to the src oncogene and tyrosine-specific protein kinase activity in Drosophila. Nature (1983) 1.38

Isolation of a sarcoma virus from a spontaneous chicken tumor. Gan (1978) 1.23

Isolation and structural mapping of a human c-src gene homologous to the transforming gene (v-src) of Rous sarcoma virus. J Virol (1985) 1.20

Analysis of the primary translational product and integrated DNA of a new feline sarcoma virus, GR-FeSV. Virology (1983) 1.15

Transforming genes of avian (v-fps) and mammalian (v-fes) retroviruses correspond to a common cellular locus. Virology (1983) 1.15

Origin and biological properties of a new feline sarcoma virus. Virology (1982) 1.13

Molecular cloning of integrated Gardner-Rasheed feline sarcoma virus: genetic structure of its cell-derived sequence differs from that of other tyrosine kinase-coding onc genes. J Virol (1983) 1.05

Localisation of the human N-ras oncogene to chromosome 1cen - p21 by in situ hybridisation. EMBO J (1983) 1.02

Regional mapping of the human proto-oncogene c-yes-1 to chromosome 18 at band q21.3. Jpn J Cancer Res (1985) 0.96

Human c-f gr gene does not contain coding sequence for actin-like protein. Jpn J Cancer Res (1985) 0.82

Articles by these authors

The human LDL receptor: a cysteine-rich protein with multiple Alu sequences in its mRNA. Cell (1984) 12.54

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice. Nature (1995) 11.06

Toward a protein-protein interaction map of the budding yeast: A comprehensive system to examine two-hybrid interactions in all possible combinations between the yeast proteins. Proc Natl Acad Sci U S A (2000) 10.98

New procedure for DNA transfection with polycation and dimethyl sulfoxide. Mol Cell Biol (1984) 8.63

A high-density rice genetic linkage map with 2275 markers using a single F2 population. Genetics (1998) 6.82

Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor. Nature (1986) 6.67

Thermodynamic parameters to predict stability of RNA/DNA hybrid duplexes. Biochemistry (1995) 6.40

Enhancement and inhibition of avian sarcoma viruses by polycations and polyanions. Virology (1969) 6.24

Identification of a functional promoter in the long terminal repeat of Rous sarcoma virus. Cell (1980) 5.51

Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho. EMBO J (1996) 5.14

Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene. Science (1997) 4.62

Novel single-balloon enteroscopy for diagnosis and treatment of the small intestine: preliminary experiences. Endoscopy (2007) 4.52

Human immunodeficiency viruses. Science (1986) 4.34

Avian sarcoma virus Y73 genome sequence and structural similarity of its transforming gene product to that of Rous sarcoma virus. Nature (1982) 4.33

Clinically mild encephalitis/encephalopathy with a reversible splenial lesion. Neurology (2004) 4.24

Domain map of the LDL receptor: sequence homology with the epidermal growth factor precursor. Cell (1984) 4.21

Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins. Nature (1994) 4.20

Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity. Science (2001) 4.13

Natural inhibitor of transforming growth factor-beta protects against scarring in experimental kidney disease. Nature (1992) 3.96

Amplification of c-erbB-2 oncogene in human adenocarcinomas in vivo. Lancet (1986) 3.93

Association of B cell antigen receptor with protein tyrosine kinase Lyn. Science (1991) 3.86

The erbB gene of avian erythroblastosis virus is a member of the src gene family. Cell (1983) 3.82

A v-erbB-related protooncogene, c-erbB-2, is distinct from the c-erbB-1/epidermal growth factor-receptor gene and is amplified in a human salivary gland adenocarcinoma. Proc Natl Acad Sci U S A (1985) 3.80

Preferential inactivation of the paternally derived X chromosome in the extraembryonic membranes of the mouse. Nature (1975) 3.75

The product of the human c-erbB-2 gene: a 185-kilodalton glycoprotein with tyrosine kinase activity. Science (1986) 3.74

Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site. Mol Cell Biol (1996) 3.72

Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient mice. Genes Cells (1999) 3.69

Characterization of Y73, an avian sarcoma virus: a unique transforming gene and its product, a phosphopolyprotein with protein kinase activity. Proc Natl Acad Sci U S A (1980) 3.58

Discovery of a cool planet of 5.5 Earth masses through gravitational microlensing. Nature (2006) 3.53

Binding of APC to the human homolog of the Drosophila discs large tumor suppressor protein. Science (1996) 3.42

Highly conserved core domain and unique N terminus with presumptive regulatory motifs in a human TATA factor (TFIID). Nature (1990) 3.42

BDCA-2, a novel plasmacytoid dendritic cell-specific type II C-type lectin, mediates antigen capture and is a potent inhibitor of interferon alpha/beta induction. J Exp Med (2001) 3.40

Identification of toxin A-negative, toxin B-positive Clostridium difficile by PCR. J Clin Microbiol (1998) 3.34

Homologous recombination at c-fyn locus of mouse embryonic stem cells with use of diphtheria toxin A-fragment gene in negative selection. Proc Natl Acad Sci U S A (1990) 3.31

Analysis of myocilin mutations in 1703 glaucoma patients from five different populations. Hum Mol Genet (1999) 3.24

Analysis of a human DNA excision repair gene involved in group A xeroderma pigmentosum and containing a zinc-finger domain. Nature (1990) 3.23

yes-related protooncogene, syn, belongs to the protein-tyrosine kinase family. Proc Natl Acad Sci U S A (1986) 3.19

TCGF (IL 2)-receptor inducing factor(s). I. Regulation of IL 2 receptor on a natural killer-like cell line (YT cells). J Immunol (1985) 3.18

Maf nuclear oncoprotein recognizes sequences related to an AP-1 site and forms heterodimers with both Fos and Jun. Mol Cell Biol (1994) 3.15

A comparative study of modified Bielschowsky, Bodian and thioflavin S stains on Alzheimer's neurofibrillary tangles. Neuropathol Appl Neurobiol (1986) 3.09

Identification of the spinocerebellar ataxia type 2 gene using a direct identification of repeat expansion and cloning technique, DIRECT. Nat Genet (1996) 3.07

Amplification and enhanced expression of the epidermal growth factor receptor gene in A431 human carcinoma cells. Science (1984) 3.06

Complete coding sequence and deduced primary structure of the human cartilage large aggregating proteoglycan, aggrecan. Human-specific repeats, and additional alternatively spliced forms. J Biol Chem (1991) 3.01

Response of anti-NMDA receptor encephalitis without tumor to immunotherapy including rituximab. Neurology (2008) 2.85

Identification of TRAF6, a novel tumor necrosis factor receptor-associated factor protein that mediates signaling from an amino-terminal domain of the CD40 cytoplasmic region. J Biol Chem (1996) 2.85

Cloning and characterization of a novel erythroid cell-derived CNC family transcription factor heterodimerizing with the small Maf family proteins. Mol Cell Biol (1995) 2.84

Purification and properties of the dnaJ replication protein of Escherichia coli. J Biol Chem (1985) 2.84

Identification of an amino acid sequence in laminin mediating cell attachment, chemotaxis, and receptor binding. Cell (1987) 2.84

Sequence of the cDNA encoding the laminin B1 chain reveals a multidomain protein containing cysteine-rich repeats. Proc Natl Acad Sci U S A (1987) 2.82

Molecular characterization of ALK, a receptor tyrosine kinase expressed specifically in the nervous system. Oncogene (1997) 2.80

Early-onset ataxia with ocular motor apraxia and hypoalbuminemia is caused by mutations in a new HIT superfamily gene. Nat Genet (2001) 2.79

Human autologous culture expanded bone marrow mesenchymal cell transplantation for repair of cartilage defects in osteoarthritic knees. Osteoarthritis Cartilage (2002) 2.78

Studies of surface immunoglobulins on human B lymphocytes. I. Dissociation of cell-bound immunoglobulins with acid pH or at 37 degrees C. J Immunol (1975) 2.77

Deletion in cysteine-rich region of LDL receptor impedes transport to cell surface in WHHL rabbit. Science (1986) 2.76

CSK: a protein-tyrosine kinase involved in regulation of src family kinases. J Biol Chem (1991) 2.75

Two erbA homologs encoding proteins with different T3 binding capacities are transcribed from opposite DNA strands of the same genetic locus. Cell (1989) 2.73

Temperature sensitive mutants of an avian sarcoma virus. Virology (1969) 2.73

K-ras is essential for the development of the mouse embryo. Oncogene (1997) 2.57

Correlation of the highest-energy cosmic rays with nearby extragalactic objects. Science (2007) 2.57

Focal adhesion kinase: at the crossroads of signal transduction. J Cell Sci (1997) 2.51

Broadband antireflection gratings fabricated upon silicon substrates. Opt Lett (1999) 2.51

Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice. Immunity (1995) 2.50

Axin, an inhibitor of the Wnt signalling pathway, interacts with beta-catenin, GSK-3beta and APC and reduces the beta-catenin level. Genes Cells (1998) 2.50

Unifected avian cells contain structurally unrelated progenitors of viral sarcoma genes. Nature (1980) 2.50

Primary structure of heat-labile enterotoxin produced by Escherichia coli pathogenic for humans. J Biol Chem (1984) 2.48

Identification of a gene conferring resistance to zinc and cadmium ions in the yeast Saccharomyces cerevisiae. Mol Gen Genet (1989) 2.46

Characterization of Fyn-mediated tyrosine phosphorylation sites on GluR epsilon 2 (NR2B) subunit of the N-methyl-D-aspartate receptor. J Biol Chem (2001) 2.46

Human intelectin is a novel soluble lectin that recognizes galactofuranose in carbohydrate chains of bacterial cell wall. J Biol Chem (2001) 2.45

Unusual features in the nucleotide sequence of a cDNA clone derived from the common region of avian sarcoma virus messenger RNA. Proc Natl Acad Sci U S A (1980) 2.45

The yes-related cellular gene lyn encodes a possible tyrosine kinase similar to p56lck. Mol Cell Biol (1987) 2.44

Expression of functional acetylcholine receptor from cloned cDNAs. Nature (1984) 2.41

Autosomal dominant non-syndromic deafness caused by a mutation in the myosin VIIA gene. Nat Genet (1997) 2.40

Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesis. EMBO J (2001) 2.37

Isolation of different kinds of non-virus producing chick cells transformed by Schmidt-Ruppin strain (subgroup A) of Rous sarcoma virus. Jpn J Exp Med (1970) 2.35

In vitro transcription of infectious RNAs from full-length cDNAs of tobacco mosaic virus. Proc Natl Acad Sci U S A (1986) 2.35

Localization of a novel v-erbB-related gene, c-erbB-2, on human chromosome 17 and its amplification in a gastric cancer cell line. Mol Cell Biol (1986) 2.33

TRAF5, a novel tumor necrosis factor receptor-associated factor family protein, mediates CD40 signaling. Proc Natl Acad Sci U S A (1996) 2.31

Specific proto-oncogenic tyrosine kinases of src family are enriched in cell-to-cell adherens junctions where the level of tyrosine phosphorylation is elevated. J Cell Biol (1991) 2.29