The human hematopoietic colony-stimulating factors.

PubWeight™: 5.86‹?› | Rank: Top 1%

🔗 View Article (PMID 3296190)

Published in Science on June 05, 1987

Authors

S C Clark, R Kamen

Associated clinical trials:

Phase I Trial of FLAC (5-Fluorouracil, Leucovorin, Adriamycin, Cytoxan) Plus GM-CSF (Granulocyte-Macrophage Colony Stimulating Factor) Plus Dose Escalation of IL-3 (Interleukin-3) in Metastatic Breast Cancer | NCT00001269

Combination Chemotherapy (FLAC) Combined With Granulocyte-Macrophage Colony Stimulating Factor in Locally Advanced and Metastatic Breast Cancer | NCT00001239

Articles citing this

(truncated to the top 100)

Efficient isolation and propagation of human immunodeficiency virus on recombinant colony-stimulating factor 1-treated monocytes. J Exp Med (1988) 9.21

Positive and negative elements regulate human interleukin 3 expression. Proc Natl Acad Sci U S A (1990) 7.44

Interleukin 6 enhancement of interleukin 3-dependent proliferation of multipotential hemopoietic progenitors. Proc Natl Acad Sci U S A (1987) 3.92

Taxonomy, biology, and clinical aspects of Fusarium species. Clin Microbiol Rev (1994) 3.58

Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): reconstitution of a high-affinity GM-CSF receptor. Proc Natl Acad Sci U S A (1990) 3.36

Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction. Proc Natl Acad Sci U S A (1993) 2.88

Nuclear proteins interacting with the promoter region of the human granulocyte/macrophage colony-stimulating factor gene. Proc Natl Acad Sci U S A (1988) 2.74

Multiple myeloma: increasing evidence for a multistep transformation process. Blood (1998) 2.29

Macrophages prevent human red blood cell reconstitution in immunodeficient mice. Blood (2011) 2.24

Selective modulation of human natural killer cells in vivo after prolonged infusion of low dose recombinant interleukin 2. J Clin Invest (1993) 2.18

Human eosinophils have prolonged survival, enhanced functional properties, and become hypodense when exposed to human interleukin 3. J Clin Invest (1988) 2.15

Critical cytoplasmic domains of the common beta subunit of the human GM-CSF, IL-3 and IL-5 receptors for growth signal transduction and tyrosine phosphorylation. EMBO J (1992) 2.11

Identification of another member of the transforming growth factor type beta gene family. Proc Natl Acad Sci U S A (1988) 2.07

Replication of human immunodeficiency virus in monocytes. Granulocyte/macrophage colony-stimulating factor (GM-CSF) potentiates viral production yet enhances the antiviral effect mediated by 3'-azido-2'3'-dideoxythymidine (AZT) and other dideoxynucleoside congeners of thymidine. J Exp Med (1989) 1.99

Regulation of apoptosis in interleukin-3-dependent hemopoietic cells by interleukin-3 and calcium ionophores. EMBO J (1990) 1.94

Reconstitution of functional receptors for human granulocyte/macrophage colony-stimulating factor (GM-CSF): evidence that the protein encoded by the AIC2B cDNA is a subunit of the murine GM-CSF receptor. Proc Natl Acad Sci U S A (1991) 1.91

Hematopoietic cell phosphatase associates with the interleukin-3 (IL-3) receptor beta chain and down-regulates IL-3-induced tyrosine phosphorylation and mitogenesis. Mol Cell Biol (1993) 1.86

Amyloid-beta peptide-receptor for advanced glycation endproduct interaction elicits neuronal expression of macrophage-colony stimulating factor: a proinflammatory pathway in Alzheimer disease. Proc Natl Acad Sci U S A (1997) 1.82

Leukotriene production in human neutrophils primed by recombinant human granulocyte/macrophage colony-stimulating factor and stimulated with the complement component C5A and FMLP as second signals. J Exp Med (1988) 1.79

Granulocyte-macrophage colony-stimulating factor promotes differentiation and survival of human peripheral blood dendritic cells in vitro. J Clin Invest (1990) 1.72

Hematopoietic growth factors activate the tyrosine phosphorylation of distinct sets of proteins in interleukin-3-dependent murine cell lines. Mol Cell Biol (1988) 1.70

The neutrophil-activating peptide NAF/NAP-1 induces histamine and leukotriene release by interleukin 3-primed basophils. J Exp Med (1989) 1.65

Inactivation of erythropoietin receptor function by point mutations in a region having homology with other cytokine receptors. Mol Cell Biol (1993) 1.62

De Novo assembly of the Japanese flounder (Paralichthys olivaceus) spleen transcriptome to identify putative genes involved in immunity. PLoS One (2015) 1.49

Granulocyte colony-stimulating factor enhances interleukin 3-dependent proliferation of multipotential hemopoietic progenitors. Proc Natl Acad Sci U S A (1988) 1.49

Interleukin 3-dependent mediator release in basophils triggered by C5a. J Exp Med (1989) 1.48

The murine myeloperoxidase promoter contains several functional elements, one of which binds a cell type-restricted transcription factor, myeloid nuclear factor 1 (MyNF1). Mol Cell Biol (1993) 1.48

Cell cycle-dependent initiation and lineage-dependent abrogation of GATA-1 expression in pure differentiating hematopoietic progenitors. Proc Natl Acad Sci U S A (1992) 1.45

Cytokines from activated T cells induce normal endothelial cells to acquire the phenotypic and functional features of AIDS-Kaposi's sarcoma spindle cells. J Clin Invest (1995) 1.43

Interleukin-1 beta and tumor necrosis factor-alpha induce gene expression and production of leukocyte chemotactic factors, colony-stimulating factors, and interleukin-6 in human mesangial cells. Am J Pathol (1991) 1.41

Distinct cytoplasmic regions of the human granulocyte colony-stimulating factor receptor involved in induction of proliferation and maturation. Mol Cell Biol (1993) 1.38

Selection of lineage-restricted cell lines immortalized at different stages of hematopoietic differentiation from the murine cell line 32D. J Cell Biol (1989) 1.37

Retracted Granulocyte-macrophage colony-stimulating factor induces cytokine secretion by human polymorphonuclear leukocytes. J Clin Invest (1989) 1.37

In vitro and in vivo activation of endothelial cells by colony-stimulating factors. J Clin Invest (1991) 1.31

Molecular regulation of the human IL-3 gene: inducible T cell-restricted expression requires intact AP-1 and Elf-1 nuclear protein binding sites. J Exp Med (1993) 1.31

Regulatory elements responsible for inducible expression of the granulocyte colony-stimulating factor gene in macrophages. Mol Cell Biol (1990) 1.29

Activation of the granulocyte-macrophage colony-stimulating factor promoter in T cells requires cooperative binding of Elf-1 and AP-1 transcription factors. Mol Cell Biol (1994) 1.28

Human granulocyte-macrophage colony-stimulating factor is a growth factor active on a variety of cell types of nonhemopoietic origin. Proc Natl Acad Sci U S A (1988) 1.27

Angiotensin II stimulates proliferation of normal early erythroid progenitors. J Clin Invest (1997) 1.19

Proliferation and differentiation of highly enriched mouse hematopoietic stem cells and progenitor cells in response to defined growth factors. J Exp Med (1988) 1.19

Ovarian adenocarcinomas express fms-complementary transcripts and fms antigen, often with coexpression of CSF-1. Am J Pathol (1990) 1.18

The control of hematopoiesis and leukemia: from basic biology to the clinic. Proc Natl Acad Sci U S A (1996) 1.18

Analysis in serum-free culture of the targets of recombinant human hemopoietic growth factors: interleukin 3 and granulocyte/macrophage-colony-stimulating factor are specific for early developmental stages. Proc Natl Acad Sci U S A (1988) 1.18

Antisense oligonucleotides from the stage-specific myeloid zinc finger gene MZF-1 inhibit granulopoiesis in vitro. J Exp Med (1991) 1.17

Characterization of a human hematopoietic progenitor cell capable of forming blast cell containing colonies in vitro. J Clin Invest (1988) 1.16

Tec kinase associates with c-kit and is tyrosine phosphorylated and activated following stem cell factor binding. Mol Cell Biol (1994) 1.15

Granulocyte-macrophage colony-stimulating factor enhances neutrophil function in acquired immunodeficiency syndrome patients. Proc Natl Acad Sci U S A (1988) 1.15

Stage-related proliferative activity determines c-myb functional requirements during normal human hematopoiesis. J Clin Invest (1990) 1.13

Phospholipase C release of basic fibroblast growth factor from human bone marrow cultures as a biologically active complex with a phosphatidylinositol-anchored heparan sulfate proteoglycan. J Cell Biol (1991) 1.13

Expression of functional human EGF receptor on murine bone marrow cells. EMBO J (1988) 1.13

Hepatocyte growth factor induces proliferation and differentiation of multipotent and erythroid hemopoietic progenitors. J Cell Biol (1994) 1.12

trans activation of granulocyte-macrophage colony-stimulating factor and the interleukin-2 receptor in transgenic mice carrying the human T-lymphotropic virus type 1 tax gene. Mol Cell Biol (1989) 1.12

Interleukin 1 binds to specific receptors on human keratinocytes and induces granulocyte macrophage colony-stimulating factor mRNA and protein. A potential autocrine role for interleukin 1 in epidermis. J Clin Invest (1988) 1.11

Selective and indirect modulation of human multipotential and erythroid hematopoietic progenitor cell proliferation by recombinant human activin and inhibin. Proc Natl Acad Sci U S A (1988) 1.11

Interleukin 1 as an autocrine growth factor for acute myeloid leukemia cells. Proc Natl Acad Sci U S A (1989) 1.11

Expression of interleukin-5 and granulocyte-macrophage colony-stimulating factor in human peripheral blood mononuclear cells after activation with phorbol myristate acetate. Immunology (1992) 1.10

Regulation of interleukin 3 gene induction in normal human T cells. J Clin Invest (1989) 1.10

High-throughput sequence analysis of turbot (Scophthalmus maximus) transcriptome using 454-pyrosequencing for the discovery of antiviral immune genes. PLoS One (2012) 1.08

Differential processing of colony-stimulating factor 1 precursors encoded by two human cDNAs. Mol Cell Biol (1988) 1.08

Reconstituted human granulocyte-macrophage colony-stimulating factor receptor transduces growth-promoting signals in mouse NIH 3T3 cells: comparison with signalling in BA/F3 pro-B cells. Mol Cell Biol (1993) 1.07

In vivo activation of neutrophil function in hamsters by recombinant human granulocyte colony-stimulating factor. Infect Immun (1988) 1.07

A novel tumor necrosis factor-responsive transcription factor which recognizes a regulatory element in hemopoietic growth factor genes. Mol Cell Biol (1990) 1.06

Erythropoietin receptor. Subunit structure and activation. J Clin Invest (1990) 1.05

The repeated sequence CATT(A/T) is required for granulocyte-macrophage colony-stimulating factor promoter activity. Mol Cell Biol (1990) 1.03

Identification of a common signal associated with cellular proliferation stimulated by four haemopoietic growth factors in a highly enriched population of granulocyte/macrophage colony-forming cells. EMBO J (1989) 1.02

v-myb blocks granulocyte colony-stimulating factor-induced myeloid cell differentiation but not proliferation. Mol Cell Biol (1993) 1.01

Control of hematopoietic differentiation: lack of specificity in signaling by cytokine receptors. Proc Natl Acad Sci U S A (1998) 1.01

Microglial progenitors with a high proliferative potential in the embryonic and adult mouse brain. Proc Natl Acad Sci U S A (1991) 1.01

Granulocyte/macrophage colony-stimulating factor is an intrinsic keratinocyte-derived growth factor for human melanocytes in UVA-induced melanosis. Biochem J (1996) 1.01

Pretreatment with granulocyte colony-stimulating factor attenuates the inflammatory response but not the bacterial load in cerebrospinal fluid during experimental pneumococcal meningitis in rabbits. Infect Immun (1999) 1.00

Growth factor-dependent inhibition of normal hematopoiesis by N-ras antisense oligodeoxynucleotides. J Exp Med (1992) 1.00

Retracted Participation of the cytokines interleukin 6, tumor necrosis factor-alpha, and interleukin 1-beta secreted by acute myelogenous leukemia blasts in autocrine and paracrine leukemia growth control. J Clin Invest (1989) 0.99

Comparative study of the cytokine/chemokine response in children with differing disease severity in enterovirus 71-induced hand, foot, and mouth disease. PLoS One (2013) 0.99

Production of granulocyte/macrophage-colony-stimulating factor by human natural killer cells. Modulation by the p75 subunit of the interleukin 2 receptor and by the CD2 receptor. J Clin Invest (1991) 0.98

Identification of a functional receptor for granulocyte colony-stimulating factor on platelets. J Clin Invest (1993) 0.98

Enhanced resistance against Listeria monocytogenes achieved by pretreatment with granulocyte colony-stimulating factor. Infect Immun (1991) 0.97

Effects of low dose GM-CSF on microglial inflammatory profiles to diverse pathogen-associated molecular patterns (PAMPs). J Neuroinflammation (2007) 0.97

Interleukin 3 stimulates proliferation and triggers endothelial-leukocyte adhesion molecule 1 gene activation of human endothelial cells. J Clin Invest (1993) 0.97

Hematopoietic activity of granulocyte/macrophage colony-stimulating factor is dependent upon two distinct regions of the molecule: functional analysis based upon the activities of interspecies hybrid growth factors. Proc Natl Acad Sci U S A (1989) 0.97

Haemopoietic growth factors. BMJ (1991) 0.96

Autoregulation of interleukin 6 and granulocyte-macrophage colony-stimulating factor in the differentiation of myeloid leukemic cells. Mol Cell Biol (1989) 0.95

Autocrine stimulation of interleukin 1 beta in acute myelogenous leukemia cells. J Exp Med (1987) 0.95

Interferon-gamma inhibits macrophage apolipoprotein E production by posttranslational mechanisms. J Clin Invest (1993) 0.95

Activating point mutations in the common beta subunit of the human GM-CSF, IL-3 and IL-5 receptors suggest the involvement of beta subunit dimerization and cell type-specific molecules in signalling. EMBO J (1995) 0.94

Involvement of a phospholipase D in the mechanism of action of granulocyte-macrophage colony-stimulating factor (GM-CSF): priming of human neutrophils in vitro with GM-CSF is associated with accumulation of phosphatidic acid and diradylglycerol. J Exp Med (1990) 0.94

The c-fms gene complements the mitogenic defect in mast cells derived from mutant W mice but not mi (microphthalmia) mice. Proc Natl Acad Sci U S A (1991) 0.93

Signal transduction of human interleukin 3 and granulocyte-macrophage colony-stimulating factor through serine and tyrosine phosphorylation. Biochem J (1990) 0.93

In vivo treatment with the herbal phenylethanoid acteoside ameliorates intestinal inflammation in dextran sulphate sodium-induced colitis. Clin Exp Immunol (2007) 0.93

Identification and cellular distribution of distinct proteins forming human GM-CSF receptor. Cell Regul (1990) 0.93

Stimulation of human prostatic carcinoma cell growth by factors present in human bone marrow. J Clin Invest (1989) 0.93

Recombinant human macrophage colony-stimulating factor (M-CSF) requires subliminal concentrations of granulocyte/macrophage (GM)-CSF for optimal stimulation of human macrophage colony formation in vitro. J Exp Med (1987) 0.91

Interleukin-3 induces antimicrobial activity against Leishmania amazonensis and Trypanosoma cruzi and tumoricidal activity in human peripheral blood-derived macrophages. Infect Immun (1992) 0.90

Interleukin 3 prevents delayed neuronal death in the hippocampal CA1 field. J Exp Med (1998) 0.90

Large-scale hematopoietic differentiation of human induced pluripotent stem cells provides granulocytes or macrophages for cell replacement therapies. Stem Cell Reports (2015) 0.89

Granulocyte-colony stimulating factor administration ameliorates liver regeneration in animal model of fulminant hepatic failure and encephalopathy. Dig Dis Sci (2003) 0.89

Regulated expression of human alpha- and beta-globin genes in transient heterokaryons. Mol Cell Biol (1991) 0.89

A human interleukin 3 analog with increased biological and binding activities. Proc Natl Acad Sci U S A (1992) 0.89

Elevated IL-5 levels in pleural fluid of patients with paragonimiasis westermani. Clin Exp Immunol (2001) 0.88

Transduction of human colony-stimulating factor-1 (CSF-1) receptor into interleukin-3-dependent mouse myeloid cells induces both CSF-1-dependent and factor-independent growth. Mol Cell Biol (1989) 0.87

Human interleukin-3 (IL-3) induces disulfide-linked IL-3 receptor alpha- and beta-chain heterodimerization, which is required for receptor activation but not high-affinity binding. Mol Cell Biol (1996) 0.87

Articles by these authors

A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell (1986) 36.96

Transcription maps of polyoma virus-specific RNA: analysis by two-dimensional nuclease S1 gel mapping. Methods Enzymol (1980) 24.43

Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes. J Exp Med (1989) 10.60

Induction of interferon gamma production by natural killer cell stimulatory factor: characterization of the responder cells and synergy with other inducers. J Exp Med (1991) 7.52

Transformation of rat cells by an altered polyoma virus genome expressing only the middle-T protein. Nature (1981) 6.70

A region of the polyoma virus genome between the replication origin and late protein coding sequences is required in cis for both early gene expression and viral DNA replication. Nucleic Acids Res (1981) 6.11

Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production. Nature (1997) 5.35

Response of resting human peripheral blood natural killer cells to interleukin 2. J Exp Med (1984) 5.26

The roles of individual polyoma virus early proteins in oncogenic transformation. Nature (1982) 4.57

Polyoma virus DNA replication requires an enhancer. Nature (1984) 4.32

Correlations and interactions in the production of interleukin-6 (IL-6), IL-1, and tumor necrosis factor (TNF) in human blood mononuclear cells: IL-6 suppresses IL-1 and TNF. Blood (1990) 4.13

Interleukin 6 enhancement of interleukin 3-dependent proliferation of multipotential hemopoietic progenitors. Proc Natl Acad Sci U S A (1987) 3.92

Polyomavirus enhancer contains multiple redundant sequence elements that activate both DNA replication and gene expression. Mol Cell Biol (1985) 3.91

Purified human granulocyte-macrophage colony-stimulating factor: direct action on neutrophils. Science (1984) 3.84

Recombinant human granulocyte-macrophage colony-stimulating factor stimulates in vitro mature human neutrophil and eosinophil function, surface receptor expression, and survival. J Clin Invest (1986) 3.78

Human granulocyte-macrophage colony-stimulating factor is a neutrophil activator. Nature (1985) 3.73

Expression of the large T protein of polyoma virus promotes the establishment in culture of "normal" rodent fibroblast cell lines. Proc Natl Acad Sci U S A (1983) 3.65

Multiple actions of interleukin 6 within a cytokine network. Immunol Today (1988) 3.62

Genetic Recombination in DNA-Induced Transformation of Pneumococcus. I. the Problem of Relative Efficiency of Transforming Factors. Genetics (1965) 3.52

B-cell-stimulatory factor 2 (beta 2 interferon) functions as a second signal for interleukin 2 production by mature murine T cells. Proc Natl Acad Sci U S A (1987) 3.33

Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells. EMBO J (1995) 3.16

Virus-specific RNA in cells productively infected or transformed by polyoma virus. Cold Spring Harb Symp Quant Biol (1975) 3.06

Awareness of illness in schizophrenia and schizoaffective and mood disorders. Arch Gen Psychiatry (1994) 2.69

The high affinity binding site on polyoma virus DNA for the viral large-T protein. Nucleic Acids Res (1981) 2.67

State and organization of polyoma virus DNA sequences in transformed rat cell lines. J Virol (1979) 2.47

Biologic properties in vitro of a recombinant human granulocyte-macrophage colony-stimulating factor. Blood (1986) 2.45

Proteolytic activation of protein kinase C delta by an ICE/CED 3-like protease induces characteristics of apoptosis. J Exp Med (1996) 2.42

Molecular characterization of genome of a novel human T-cell leukaemia virus. Nature (1983) 2.36

Stimulation of haematopoiesis in primates by continuous infusion of recombinant human GM-CSF. Nature (1986) 2.36

Sequences at the capped 5'-ends of polyoma virus late region mRNAs: an example of extreme terminal heterogeneity. Nucleic Acids Res (1981) 2.32

Multiple binding sites for polyomavirus large T antigen within regulatory sequences of polyomavirus DNA. J Virol (1984) 2.25

Characterization of the subunits of Q-beta replicase. Nature (1970) 2.24

Molecular cloning of a cDNA encoding a human macrophage migration inhibitory factor. Proc Natl Acad Sci U S A (1989) 2.24

Multiple 5' terminal cap structures in late polyoma virus RNA. Cell (1979) 2.21

B cell stimulatory factor-2 is involved in the differentiation of cytotoxic T lymphocytes. J Immunol (1988) 2.20

Expression of human interleukin-3 (multi-CSF) is restricted to human lymphocytes and T-cell tumor lines. Blood (1989) 2.13

Human T-cell growth factor: partial amino acid sequence, cDNA cloning, and organization and expression in normal and leukemic cells. Proc Natl Acad Sci U S A (1984) 2.12

Molecular cloning of a cDNA encoding interleukin 11, a stromal cell-derived lymphopoietic and hematopoietic cytokine. Proc Natl Acad Sci U S A (1990) 2.03

Construction and functional characterization of polyomavirus genomes that separately encode the three early proteins. J Virol (1984) 2.02

Comparison of polyoma virus transcription in productively infected mouse cells and transformed rodent cell lines. Cold Spring Harb Symp Quant Biol (1980) 1.98

Topography of polyoma virus messenger RNA molecules. Cell (1976) 1.94

Suppression of in vitro haematopoiesis following human immunodeficiency virus infection. Nature (1987) 1.91

Reconstitution of Q replicase lacking subunit with protein-synthesis-interference factor i. Eur J Biochem (1972) 1.88

Human recombinant granulocyte-macrophage colony-stimulating factor: a multilineage hematopoietin. Science (1985) 1.86

Analysis of polyoma virus nuclear RNA by mini-blot hybridization. Proc Natl Acad Sci U S A (1977) 1.86

5' termini of polyoma virus early region transcripts synthesized in vivo by wild-type virus and viable deletion mutants. J Mol Biol (1982) 1.82

Human recombinant granulocyte-macrophage colony-stimulating factor increases cell-to-cell adhesion and surface expression of adhesion-promoting surface glycoproteins on mature granulocytes. J Clin Invest (1986) 1.76

Amplification in the leader sequence of late polyoma virus mRNAs. Cell (1979) 1.74

Production of hematopoietic colony-stimulating factors by human natural killer cells. J Exp Med (1989) 1.67

Localization of three major cappe 5' ends of polyoma virus late mRNA's within a single tetranucleotide sequence in the viral genome. J Virol (1980) 1.66

The interleukin 3 gene is located on human chromosome 5 and is deleted in myeloid leukemias with a deletion of 5q. Proc Natl Acad Sci U S A (1987) 1.64

Location of the sequences coding for capsid proteins VP1 and VP2 on polyoma virus DNA. Cell (1976) 1.63

Topography of the three late mRNA's of polyoma virus which encode the virion proteins. J Virol (1980) 1.59

The human genes for GM-CSF and IL 3 are closely linked in tandem on chromosome 5. Blood (1988) 1.54

Structure of polyoma virus late nuclear RNA. J Mol Biol (1981) 1.54

Stimulation of murine hemopoietic colony formation by human IL-6. J Immunol (1988) 1.54

Leukaemia inhibitory factor is identical to the myeloid growth factor human interleukin for DA cells. Nature (1988) 1.51

Comparison of the effects of IL-3, granulocyte-macrophage colony-stimulating factor, and macrophage colony-stimulating factor in supporting monocyte differentiation in culture. Analysis of macrophage antibody-dependent cellular cytotoxicity. J Immunol (1990) 1.51

A new method for the purification of Q RNA-dependent RNA polymerase. Biochim Biophys Acta (1972) 1.49

Granulocyte colony-stimulating factor enhances interleukin 3-dependent proliferation of multipotential hemopoietic progenitors. Proc Natl Acad Sci U S A (1988) 1.49

The myeloid blood cell differentiation-inducing protein MGI-2A is interleukin-6. Blood (1988) 1.47

Arrangement of 30S heterogeneous nuclear ribonucleoprotein on polyoma virus late nuclear transcripts. Mol Cell Biol (1981) 1.47

HTLV x-gene product: requirement for the env methionine initiation codon. Science (1985) 1.45

Expression of the 3' terminal region of human T-cell leukemia viruses. Science (1984) 1.44

Solitary fibrous tumour of the diaphragm. J Cardiovasc Surg (Torino) (1997) 1.44

Recombinant human granulocyte/macrophage colony-stimulating factor activates intracellular killing of Leishmania donovani by human monocyte-derived macrophages. J Exp Med (1987) 1.41

Composition and functional integrity of the in vitro hemopoietic microenvironment in acute myelogenous leukemia: effect of macrophage colony-stimulating factor. Exp Hematol (1992) 1.40

Determination of sequences at the capped 5' ends of polyoma virus early region transcripts synthesized in vivo and in vitro demonstrates an unusual microheterogeneity. J Mol Biol (1982) 1.39

Guanine nucleotide contacts within viral DNA sequences bound by polyomavirus large T antigen. J Virol (1986) 1.37

Purification of fetal hematopoietic progenitors and demonstration of recombinant multipotential colony-stimulating activity. J Clin Invest (1985) 1.36

The effects of three recombinant growth factors, IL-3, GM-CSF, and G-CSF, on the blast cells of acute myeloblastic leukemia maintained in short-term suspension culture. Blood (1987) 1.36

Synergism between interleukin-6 and interleukin-3 in supporting proliferation of human hematopoietic stem cells: comparison with interleukin-1 alpha. Blood (1988) 1.35

DNA sequences required for specific and efficient initiation of transcription at the polyoma virus early promoter. Mol Cell Biol (1982) 1.34

Recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF) shortens the period of neutropenia after autologous bone marrow transplantation in a primate model. J Clin Invest (1987) 1.33

RFLP detected by an X-linked cDNA encoding erythroid-potentiating activity/tissue inhibitor of metalloproteinase (EPA/TIMP). Nucleic Acids Res (1986) 1.33

The structures of the spliced mRNAs encoding polyoma virus early region proteins. J Mol Appl Genet (1981) 1.28

Release of early human hematopoietic progenitors from quiescence by antisense transforming growth factor beta 1 or Rb oligonucleotides. J Exp Med (1991) 1.27

Human interleukin-3 inhibits the binding of granulocyte-macrophage colony-stimulating factor and interleukin-5 to basophils and strongly enhances their functional activity. J Cell Physiol (1990) 1.23

Orientation of the complementary strands of polyoma virus DNA with respect to the DNA physical map. J Virol (1975) 1.23

APOBEC-2, a cardiac- and skeletal muscle-specific member of the cytidine deaminase supergene family. Biochem Biophys Res Commun (1999) 1.23

Comparison of the polyoma virus early and late promoters by transcription in vitro. Nucleic Acids Res (1982) 1.22

Recombinant gibbon interleukin 3 supports formation of human multilineage colonies and blast cell colonies in culture: comparison with recombinant human granulocyte-macrophage colony-stimulating factor. Blood (1987) 1.21

Direct and synergistic effects of interleukin 11 on murine hemopoiesis in culture. Proc Natl Acad Sci U S A (1991) 1.18

Enhancement of murine hematopoiesis by synergistic interactions between steel factor (ligand for c-kit), interleukin-11, and other early acting factors in culture. Blood (1992) 1.18

Analysis in serum-free culture of the targets of recombinant human hemopoietic growth factors: interleukin 3 and granulocyte/macrophage-colony-stimulating factor are specific for early developmental stages. Proc Natl Acad Sci U S A (1988) 1.18

The flt3 ligand supports proliferation of lymphohematopoietic progenitors and early B-lymphoid progenitors. Blood (1995) 1.17

Host subunit of Q replicase is translation control factor i. Nat New Biol (1972) 1.17

Recombinant human interleukin-3 and granulocyte-macrophage colony-stimulating factor show common biological effects and binding characteristics on human monocytes. Blood (1989) 1.15

Clonal proliferation of murine lymphohemopoietic progenitors in culture. Proc Natl Acad Sci U S A (1992) 1.15

Leukemia inhibitory factor differentiation-inhibiting activity/human interleukin for DA cells augments proliferation of human hematopoietic stem cells. Blood (1990) 1.12

M-07e human leukemic factor-dependent cell line provides a rapid and sensitive bioassay for the human cytokines GM-CSF and IL-3. J Cell Physiol (1990) 1.12

Growth factor requirements for survival in G0 and entry into the cell cycle of primitive human hemopoietic progenitors. Proc Natl Acad Sci U S A (1992) 1.11

Stage-specific expression of c-kit protein by murine hematopoietic progenitors. Blood (1993) 1.11

Synergistic factors for stem cell proliferation: further studies of the target stem cells and the mechanism of stimulation by interleukin-1, interleukin-6, and granulocyte colony-stimulating factor. Blood (1988) 1.10

Infectivity of bacteriophage R17 RNA after sequential removal of 3' terminal nucleotides. Nature (1969) 1.10

A possible autocrine role for interleukin-6 in two lymphoma cell lines. Blood (1989) 1.09

Synergistic and antagonistic effects of recombinant human interleukin (IL) 3, IL-1 alpha, granulocyte and macrophage colony-stimulating factors (G-CSF and M-CSF) on the growth of GM-CSF-dependent leukemic cell lines. J Immunol (1987) 1.09

Immortalization of rat embryo fibroblasts by mutant polyomavirus large T antigens deficient in DNA binding. Mol Cell Biol (1986) 1.08