Published in PLoS One on May 18, 2012
De Novo assembly of the Japanese flounder (Paralichthys olivaceus) spleen transcriptome to identify putative genes involved in immunity. PLoS One (2015) 1.49
Deep sequencing for de novo construction of a marine fish (Sparus aurata) transcriptome database with a large coverage of protein-coding transcripts. BMC Genomics (2013) 1.00
Transcriptome analysis of androgenic gland for discovery of novel genes from the oriental river prawn, Macrobrachium nipponense, using Illumina Hiseq 2000. PLoS One (2013) 0.91
Genetic architecture of sex determination in fish: applications to sex ratio control in aquaculture. Front Genet (2014) 0.91
A combined strategy involving Sanger and 454 pyrosequencing increases genomic resources to aid in the management of reproduction, disease control and genetic selection in the turbot (Scophthalmus maximus). BMC Genomics (2013) 0.90
Characterization of Liaoning cashmere goat transcriptome: sequencing, de novo assembly, functional annotation and comparative analysis. PLoS One (2013) 0.88
Analysis of the skin transcriptome in two oujiang color varieties of common carp. PLoS One (2014) 0.86
Characterization of the rainbow trout spleen transcriptome and identification of immune-related genes. Front Genet (2014) 0.86
Development and Validation of Single Nucleotide Polymorphisms (SNPs) Markers from Two Transcriptome 454-Runs of Turbot (Scophthalmus maximus) Using High-Throughput Genotyping. Int J Mol Sci (2013) 0.84
De novo assembly of mud loach (Misgurnus anguillicaudatus) skin transcriptome to identify putative genes involved in immunity and epidermal mucus secretion. PLoS One (2013) 0.83
De novo assembly of the Indo-Pacific humpback dolphin leucocyte transcriptome to identify putative genes involved in the aquatic adaptation and immune response. PLoS One (2013) 0.83
De novo assembly, characterization and functional annotation of Senegalese sole (Solea senegalensis) and common sole (Solea solea) transcriptomes: integration in a database and design of a microarray. BMC Genomics (2014) 0.81
Molecular analysis of endocrine disruption in hornyhead turbot at wastewater outfalls in southern california using a second generation multi-species microarray. PLoS One (2013) 0.80
Transcriptome profiling analysis on whole bodies of microbial challenged Eriocheir sinensis larvae for immune gene identification and SNP development. PLoS One (2013) 0.80
Whole genome sequencing of turbot (Scophthalmus maximus; Pleuronectiformes): a fish adapted to demersal life. DNA Res (2016) 0.79
Proliferation and resistance difference of a liver-parasitized myxosporean in two different gynogenetic clones of gibel carp. Parasitol Res (2014) 0.79
Transcriptome profiles associated to VHSV infection or DNA vaccination in turbot (Scophthalmus maximus). PLoS One (2014) 0.78
Transcriptome analysis of the Trachinotus ovatus: identification of reproduction, growth and immune-related genes and microsatellite markers. PLoS One (2014) 0.78
The Function of Fish Cytokines. Biology (Basel) (2016) 0.78
Whole transcriptome analysis using next-generation sequencing of sterile-cultured Eisenia andrei for immune system research. PLoS One (2015) 0.77
Second generation physical and linkage maps of yellowtail (Seriola quinqueradiata) and comparison of synteny with four model fish. BMC Genomics (2015) 0.76
Turbot (Scophthalmus maximus) vs. VHSV (Viral Hemorrhagic Septicemia Virus): A Review. Front Physiol (2016) 0.75
Transcriptome Analysis for Identification of Genes Related to Gonad Differentiation, Growth, Immune Response and Marker Discovery in The Turbot (Scophthalmus maximus). PLoS One (2016) 0.75
Characterization of the Transcriptome and Gene Expression of Brain Tissue in Sevenband Grouper (Hyporthodus septemfasciatus) in Response to NNV Infection. Genes (Basel) (2017) 0.75
The transcriptome of metamorphosing flatfish. BMC Genomics (2016) 0.75
Basic local alignment search tool. J Mol Biol (1990) 659.07
KEGG: kyoto encyclopedia of genes and genomes. Nucleic Acids Res (2000) 117.00
Blast2GO: a universal tool for annotation, visualization and analysis in functional genomics research. Bioinformatics (2005) 46.40
TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol (1989) 31.72
Apoptosis: a review of programmed cell death. Toxicol Pathol (2007) 17.92
High-throughput functional annotation and data mining with the Blast2GO suite. Nucleic Acids Res (2008) 13.51
Using the miraEST assembler for reliable and automated mRNA transcript assembly and SNP detection in sequenced ESTs. Genome Res (2004) 10.40
TLR signaling pathways. Semin Immunol (2004) 9.08
Positive and negative selection of T cells. Annu Rev Immunol (2002) 8.32
MHC-dependent antigen processing and peptide presentation: providing ligands for T lymphocyte activation. Cell (1994) 6.92
Peptide antimicrobial agents. Clin Microbiol Rev (2006) 6.04
The human hematopoietic colony-stimulating factors. Science (1987) 5.86
Toll-like receptor signaling pathways. Science (2003) 5.86
The complement system in regulation of adaptive immunity. Nat Immunol (2004) 4.58
Simple cDNA normalization using kamchatka crab duplex-specific nuclease. Nucleic Acids Res (2004) 3.99
Biology and biochemistry of the chemokines: a family of chemotactic and inflammatory cytokines. Crit Rev Immunol (1992) 3.81
A hitchhiker's guide to expressed sequence tag (EST) analysis. Brief Bioinform (2006) 3.36
Affinity dependence of the B cell response to antigen: a threshold, a ceiling, and the importance of off-rate. Immunity (1998) 3.27
Hyaluronan as an immune regulator in human diseases. Physiol Rev (2011) 2.74
Proteinase-activated receptors: transducers of proteinase-mediated signaling in inflammation and immune response. Endocr Rev (2005) 2.42
Complement: a unique innate immune sensor for danger signals. Mol Immunol (2004) 2.42
B cell signaling and fate decision. Annu Rev Immunol (2010) 2.33
The structural basis for membrane binding and pore formation by lymphocyte perforin. Nature (2010) 2.23
Antifreeze Proteins: Structures and Mechanisms of Function. Chem Rev (1996) 2.05
A novel method for SNP detection using a new duplex-specific nuclease from crab hepatopancreas. Genome Res (2002) 1.98
Haptoglobin, inflammation and disease. Trans R Soc Trop Med Hyg (2008) 1.94
Cationic host defence peptides: innate immune regulatory peptides as a novel approach for treating infections. Cell Mol Life Sci (2007) 1.79
Caspase substrates and cellular remodeling. Annu Rev Biochem (2011) 1.79
Immunomodulatory properties of defensins and cathelicidins. Curr Top Microbiol Immunol (2006) 1.76
Viral infection and iron metabolism. Nat Rev Microbiol (2008) 1.61
Characterization of the rainbow trout transcriptome using Sanger and 454-pyrosequencing approaches. BMC Genomics (2010) 1.61
EST clustering error evaluation and correction. Bioinformatics (2004) 1.54
Emerging viral diseases of fish and shrimp. Vet Res (2010) 1.53
Heme scavenging and the other facets of hemopexin. Antioxid Redox Signal (2010) 1.52
Immunocalins: a lipocalin subfamily that modulates immune and inflammatory responses. Biochim Biophys Acta (2000) 1.41
Sequencing, de novo annotation and analysis of the first Anguilla anguilla transcriptome: EeelBase opens new perspectives for the study of the critically endangered European eel. BMC Genomics (2010) 1.39
Expressed sequence tags--ESTablishing bridges between genomes. Trends Genet (1998) 1.38
Alpha-1-antitrypsin is an endogenous inhibitor of proinflammatory cytokine production in whole blood. J Leukoc Biol (2009) 1.37
Overview of the immune response. J Allergy Clin Immunol (2010) 1.32
Fish immunity and parasite infections: from innate immunity to immunoprophylactic prospects. Vet Immunol Immunopathol (2008) 1.29
Animal lectins: a historical introduction and overview. Biochim Biophys Acta (2002) 1.20
Herring antifreeze protein: primary structure and evidence for a C-type lectin evolutionary origin. Mol Mar Biol Biotechnol (1993) 1.17
Immunostimulatory combinations: designing the next generation of vaccine adjuvants. J Leukoc Biol (2006) 1.10
alpha(1)-Microglobulin: a yellow-brown lipocalin. Biochim Biophys Acta (2000) 1.08
Transcriptome analysis of female and male Xiphophorus maculatus Jp 163 A. PLoS One (2011) 1.04
Fibrinogen and fibrin induce synthesis of proinflammatory cytokines from isolated peripheral blood mononuclear cells. Thromb Haemost (2007) 1.03
Keratinocytes and cytokine/growth factors. Crit Rev Oral Biol Med (1996) 0.99
Immunomodulators as adjuvants for vaccines and antimicrobial therapy. Ann N Y Acad Sci (2010) 0.97
Conventional and unconventional antimicrobials from fish, marine invertebrates and micro-algae. Mar Drugs (2010) 0.96
Expressed sequence tags (ESTs) from immune tissues of turbot (Scophthalmus maximus) challenged with pathogens. BMC Vet Res (2008) 0.95
Apolipoproteins A-I and A-II are potentially important effectors of innate immunity in the teleost fish Cyprinus carpio. Eur J Biochem (2004) 0.94
Apolipoprotein A-I, an antimicrobial protein in Oncorhynchus mykiss: evaluation of its expression in primary defence barriers and plasma levels in sick and healthy fish. Fish Shellfish Immunol (2006) 0.94
On the structure and function of apolipoproteins: more than a family of lipid-binding proteins. Prog Biophys Mol Biol (2003) 0.93
Local expression of apolipoprotein A-I gene and a possible role for HDL in primary defence in the carp skin. Fish Shellfish Immunol (2003) 0.91
Comparative analysis of the global transcriptome of Anopheles funestus from Mali, West Africa. PLoS One (2009) 0.91
Proinflammatory role of trypsin and protease-activated receptor-2 in a rat model of acute pancreatitis. Pancreas (2005) 0.89
Pro-inflammatory effect of fibrinogen and FDP on vascular smooth muscle cells by IL-6, TNF-α and iNOS. Life Sci (2011) 0.88
Inhibition of virus-induced cell fusion by apolipoprotein A-I and its amphipathic peptide analogs. J Cell Biochem (1991) 0.88
Design and performance of a turbot (Scophthalmus maximus) oligo-microarray based on ESTs from immune tissues. Mar Biotechnol (NY) (2009) 0.88
Homologue of mammalian apolipoprotein A-II in non-mammalian vertebrates. Acta Biochim Biophys Sin (Shanghai) (2009) 0.86
Characterization of the capsid protein gene from a nodavirus strain affecting the Atlantic halibut Hippoglossus hippoglossus and design of an optimal reverse-transcriptase polymerase chain reaction (RT-PCR) detection assay. Dis Aquat Organ (2000) 0.86
Antimicrobial activity of lipoprotein particles containing apolipoprotein Al. Mol Cell Biochem (1993) 0.86
Defensins--non-antibiotic use for vaccine development. Curr Protein Pept Sci (2005) 0.82
Suppression subtraction hybridization (SSH) and macroarray techniques reveal differential gene expression profiles in brain of sea bream infected with nodavirus. Mol Immunol (2006) 0.82
Serotransferrin, ovotransferrin and metallothionein levels during an immune response in chickens. Comp Biochem Physiol Biochem Mol Biol (1994) 0.81
Identification of immune-related genes from kidney and spleen of turbot, Psetta maxima (L.), by suppression subtractive hybridization following challenge with Vibrio harveyi. J Fish Dis (2008) 0.80
Nodavirus increases the expression of Mx and inflammatory cytokines in fish brain. Mol Immunol (2007) 0.80
Immunological responses of turbot (Psetta maxima) to nodavirus infection or polyriboinosinic polyribocytidylic acid (pIC) stimulation, using expressed sequence tags (ESTs) analysis and cDNA microarrays. Fish Shellfish Immunol (2008) 0.79
Identification of immune genes in grass carp Ctenopharyngodon idella in response to infection of the parasitic copepod Sinergasilus major. Parasitol Res (2005) 0.76
Structure-activity analysis of an antimicrobial peptide derived from bovine apolipoprotein A-II. J Biochem (2002) 0.76
Transcriptome and genome sequencing uncovers functional variation in humans. Nature (2013) 8.89
Skin pigmentation, biogeographical ancestry and admixture mapping. Hum Genet (2003) 4.67
Recurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy. Nat Genet (2013) 2.44
The 8818G allele of the agouti signaling protein (ASIP) gene is ancestral and is associated with darker skin color in African Americans. Hum Genet (2005) 1.97
Efficacy of hypomethylating agents in therapy-related myelodysplastic syndromes. Leuk Res (2012) 1.47
Clathrin-dependent and independent endocytosis of glucose transporter 4 (GLUT4) in myoblasts: regulation by mitochondrial uncoupling. Traffic (2008) 1.31
Perkinsoide chabelardi n. gen., a protozoan parasite with an intermediate evolutionary position: possible cause of the decrease of sardine fisheries? Environ Microbiol (2006) 1.26
Fish under exercise. Fish Physiol Biochem (2011) 1.23
The effects of duodenal-jejunal exclusion on hormonal regulation of glucose metabolism in Goto-Kakizaki rats. Am J Surg (2007) 1.21
Endotoxin recognition: in fish or not in fish? FEBS Lett (2005) 1.18
MytiBase: a knowledgebase of mussel (M. galloprovincialis) transcribed sequences. BMC Genomics (2009) 1.18
Bacterial communities from shoreline environments (costa da morte, northwestern Spain) affected by the prestige oil spill. Appl Environ Microbiol (2009) 1.16
Zebrafish: model for the study of inflammation and the innate immune response to infectious diseases. Adv Exp Med Biol (2012) 1.15
Insights into the innate immunity of the Mediterranean mussel Mytilus galloprovincialis. BMC Genomics (2011) 1.05
Zebrafish (Danio rerio) as a model for the study of vaccination against viral haemorrhagic septicemia virus (VHSV). Vaccine (2006) 0.99
Guanosine protects human neuroblastoma SH-SY5Y cells against mitochondrial oxidative stress by inducing heme oxigenase-1 via PI3K/Akt/GSK-3β pathway. Neurochem Int (2012) 0.99
Evaluation of candidate reference genes for QPCR during ontogenesis and of immune-relevant tissues of European seabass (Dicentrarchus labrax). Comp Biochem Physiol B Biochem Mol Biol (2009) 0.98
Deep RNA sequencing of the skeletal muscle transcriptome in swimming fish. PLoS One (2013) 0.98
Establishing zebrafish as a novel exercise model: swimming economy, swimming-enhanced growth and muscle growth marker gene expression. PLoS One (2010) 0.97
Comparative analysis of dental enamel polyvinylsiloxane impression and polyurethane casting methods for SEM research. Microsc Res Tech (2006) 0.97
AMP-activated protein kinase plays an important evolutionary conserved role in the regulation of glucose metabolism in fish skeletal muscle cells. PLoS One (2012) 0.96
Scrapie infectivity is quickly cleared in tissues of orally-infected farmed fish. BMC Vet Res (2006) 0.96
Tumor necrosis factors. Dev Comp Immunol (2004) 0.96
Analysis of genes isolated from lipopolysaccharide-stimulated rainbow trout (Oncorhynchus mykiss) macrophages. Mol Immunol (2004) 0.95
Expression of rainbow trout glucose transporters GLUT1 and GLUT4 during in vitro muscle cell differentiation and regulation by insulin and IGF-I. Am J Physiol Regul Integr Comp Physiol (2008) 0.95
The C1q domain containing proteins of the Mediterranean mussel Mytilus galloprovincialis: a widespread and diverse family of immune-related molecules. Dev Comp Immunol (2011) 0.95
Neurotoxicity induced by okadaic acid in the human neuroblastoma SH-SY5Y line can be differentially prevented by α7 and β2* nicotinic stimulation. Toxicol Sci (2011) 0.94
Expression and role of Elovl4 elongases in biosynthesis of very long-chain fatty acids during zebrafish Danio rerio early embryonic development. Biochim Biophys Acta (2010) 0.94
Thermal evolution of gene expression profiles in Drosophila subobscura. BMC Evol Biol (2007) 0.94
LPS-stimulated expression of a tumor necrosis factor-alpha mRNA in primary trout monocytes and in vitro differentiated macrophages. Dev Comp Immunol (2003) 0.94
Profiling of infection specific mRNA transcripts of the European seabass Dicentrarchus labrax. BMC Genomics (2009) 0.93
Thyroid hormones down-regulate thyrotropin beta subunit and thyroglobulin during metamorphosis in the flatfish Senegalese sole (Solea senegalensis Kaup). Gen Comp Endocrinol (2007) 0.92
Transcriptomics of in vitro immune-stimulated hemocytes from the Manila clam Ruditapes philippinarum using high-throughput sequencing. PLoS One (2012) 0.92
Genomic resources for a commercial flatfish, the Senegalese sole (Solea senegalensis): EST sequencing, oligo microarray design, and development of the Soleamold bioinformatic platform. BMC Genomics (2008) 0.92
High sequence variability of myticin transcripts in hemocytes of immune-stimulated mussels suggests ancient host-pathogen interactions. Dev Comp Immunol (2007) 0.92
Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. BMC Dev Biol (2010) 0.91
Comparative analysis of the acute response of the trout, O. mykiss, head kidney to in vivo challenge with virulent and attenuated infectious hematopoietic necrosis virus and LPS-induced inflammation. BMC Genomics (2008) 0.91
Cholinergic and neuroprotective drugs for the treatment of Alzheimer and neuronal vascular diseases. II. Synthesis, biological assessment, and molecular modelling of new tacrine analogues from highly substituted 2-aminopyridine-3-carbonitriles. Bioorg Med Chem (2010) 0.91
beta-Glucan administration enhances disease resistance and some innate immune responses in zebrafish (Danio rerio). Fish Shellfish Immunol (2009) 0.91
A combined strategy involving Sanger and 454 pyrosequencing increases genomic resources to aid in the management of reproduction, disease control and genetic selection in the turbot (Scophthalmus maximus). BMC Genomics (2013) 0.90
Conserved chromosomal clustering of genes governed by chromatin regulators in Drosophila. Genome Biol (2008) 0.90
New insights into the apoptotic process in mollusks: characterization of caspase genes in Mytilus galloprovincialis. PLoS One (2011) 0.89
Transcriptomic characterization of the larval stage in gilthead seabream (Sparus aurata) by 454 pyrosequencing. Mar Biotechnol (NY) (2011) 0.89
Evolutionary conserved pro-inflammatory and antigen presentation functions of zebrafish IFNγ revealed by transcriptomic and functional analysis. Mol Immunol (2011) 0.89
Transcriptional assessment by microarray analysis and large-scale meta-analysis of the metabolic capacity of cardiac and skeletal muscle tissues to cope with reduced nutrient availability in Gilthead Sea Bream (Sparus aurata L.). Mar Biotechnol (NY) (2014) 0.88
EuFishBioMed (COST Action BM0804): a European network to promote the use of small fishes in biomedical research. Zebrafish (2012) 0.88
Effects of follicle stimulating hormone on estradiol-17 beta production and P-450 aromatase (CYP19) activity and mRNA expression in brown trout vitellogenic ovarian follicles in vitro. Gen Comp Endocrinol (2004) 0.87
Calcium signalling mediated through α7 and non-α7 nAChR stimulation is differentially regulated in bovine chromaffin cells to induce catecholamine release. Br J Pharmacol (2011) 0.86
MgC1q, a novel C1q-domain-containing protein involved in the immune response of Mytilus galloprovincialis. Dev Comp Immunol (2010) 0.86
Evolution of a multifunctional gene: The warm temperature acclimation protein Wap65 in the European seabass Dicentrarchus labrax. Mol Phylogenet Evol (2009) 0.86
Relationship between blood concentrations of heavy metals and cytogenetic and endocrine parameters among subjects involved in cleaning coastal areas affected by the 'Prestige' tanker oil spill. Chemosphere (2008) 0.85
Functional characterization of an insulin-responsive glucose transporter (GLUT4) from fish adipose tissue. Am J Physiol Endocrinol Metab (2004) 0.85
N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease. Eur J Med Chem (2011) 0.85
Zebrafish fin immune responses during high mortality infections with viral haemorrhagic septicemia rhabdovirus. A proteomic and transcriptomic approach. BMC Genomics (2010) 0.85
Fish glucose transporter (GLUT)-4 differs from rat GLUT4 in its traffic characteristics but can translocate to the cell surface in response to insulin in skeletal muscle cells. Endocrinology (2007) 0.85
Bacterioplankton composition of the coastal upwelling system of 'Ría de Vigo', NW Spain. FEMS Microbiol Ecol (2009) 0.85
Cellular and molecular evidence for a role of tumor necrosis factor alpha in the ovulatory mechanism of trout. Reprod Biol Endocrinol (2010) 0.85
Identification of quantitative trait loci associated with resistance to viral haemorrhagic septicaemia (VHS) in turbot (Scophthalmus maximus ): a comparison between bacterium, parasite and virus diseases. Mar Biotechnol (NY) (2014) 0.84
Endotoxin recognition in fish results in inflammatory cytokine secretion not gene expression. Innate Immun (2010) 0.84
Mytilus galloprovincialis myticin C: a chemotactic molecule with antiviral activity and immunoregulatory properties. PLoS One (2011) 0.84
Immune responses of mussel hemocyte subpopulations are differentially regulated by enzymes of the PI 3-K, PKC, and ERK kinase families. Dev Comp Immunol (2007) 0.84
Saving energy to fuel exercise: swimming suppresses oocyte development and downregulates ovarian transcriptomic response of rainbow trout Oncorhynchus mykiss. Am J Physiol Regul Integr Comp Physiol (2010) 0.84
Adding banding ligation is effective as rescue therapy to prevent variceal rebleeding in haemodynamic non-responders to pharmacological therapy. Dig Liver Dis (2011) 0.84
Bacterial lipopolysaccharide induces apoptosis in the trout ovary. Reprod Biol Endocrinol (2006) 0.84
Next generation sequencing gives an insight into the characteristics of highly selected breeds versus non-breed horses in the course of domestication. BMC Genomics (2014) 0.83
Synthesis, inhibitory activity of cholinesterases, and neuroprotective profile of novel 1,8-naphthyridine derivatives. J Med Chem (2010) 0.83
Involvement of pore-forming molecules in immune defense and development of the Mediterranean mussel (Mytilus galloprovincialis). Dev Comp Immunol (2011) 0.83
Mechanisms regulating GLUT4 transcription in skeletal muscle cells are highly conserved across vertebrates. PLoS One (2013) 0.83