Published in J Bacteriol on October 01, 1977
Yeast chromosome replication and segregation. Microbiol Rev (1988) 3.40
Construction, replication, and chromatin structure of TRP1 RI circle, a multiple-copy synthetic plasmid derived from Saccharomyces cerevisiae chromosomal DNA. Mol Cell Biol (1982) 2.85
Yeast gene CDC8 encodes thymidylate kinase and is complemented by herpes thymidine kinase gene TK. Proc Natl Acad Sci U S A (1984) 2.36
Cell cycle-dependent expression of thymidylate synthase in Saccharomyces cerevisiae. Mol Cell Biol (1984) 2.11
Temperature-sensitive mutations in the yeast DNA polymerase I gene. Proc Natl Acad Sci U S A (1987) 2.09
Yeast cdc35 mutants are defective in adenylate cyclase and are allelic with cyr1 mutants while CAS1, a new gene, is involved in the regulation of adenylate cyclase. EMBO J (1985) 2.04
Maintenance and integrity of the mitochondrial genome: a plethora of nuclear genes in the budding yeast. Microbiol Mol Biol Rev (2000) 2.02
Cell division from a genetic perspective. J Cell Biol (1978) 1.68
Thymidine utilization by tut mutants and facile cloning of mutant alleles by plasmid conversion in S. cerevisiae. Genetics (1986) 1.63
Identification of tubulin from the yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1978) 1.57
Yeast mating pheromone alpha factor inhibits adenylate cyclase. Proc Natl Acad Sci U S A (1980) 1.57
Efficient labeling of fission yeast Schizosaccharomyces pombe with thymidine and BUdR. Nucleic Acids Res (2003) 1.51
G1 cyclin degradation: the PEST motif of yeast Cln2 is necessary, but not sufficient, for rapid protein turnover. Mol Cell Biol (1994) 1.36
CHL12, a gene essential for the fidelity of chromosome transmission in the yeast Saccharomyces cerevisiae. Genetics (1994) 1.27
Isolation of yeast DNA replication mutants in permeabilized cells. Proc Natl Acad Sci U S A (1983) 1.23
Mutations in the pho80 gene confer permeability to 5'-mononucleotides in Saccharomyces cerevisiae. Genetics (1982) 1.08
Induction of mitotic recombination in yeast by starvation for thymine nucleotides. Proc Natl Acad Sci U S A (1980) 1.04
Isolation of the thymidylate synthetase gene (TMP1) by complementation in Saccharomyces cerevisiae. Mol Cell Biol (1982) 1.03
Cloning, purification, and properties of Candida albicans thymidylate synthase. J Bacteriol (1989) 1.02
Genetic and molecular analysis of the SOE1 gene: a tRNA(3Glu) missense suppressor of yeast cdc8 mutations. Genetics (1990) 0.95
Replication of bromodeoxyuridylate-substituted mitochondrial DNA in yeast. J Bacteriol (1978) 0.95
Induction of intrachromosomal recombination in yeast by inhibition of thymidylate biosynthesis. Genetics (1986) 0.92
Exogenous dTMP utilization by a novel tup mutant of Saccharomyces cerevisiae. J Bacteriol (1982) 0.90
Thymidine-requiring mutants of Dictyostelium discoideum. Mol Cell Biol (1984) 0.90
Molecular cloning and expression of the human deoxythymidylate kinase gene in yeast. Nucleic Acids Res (1991) 0.89
Significance of ribosomal ribonucleic acid synthesis for control of the G1 period in the cell cycle of the heterobasidiomycetous yeast Rhodosporidium toruloides. J Bacteriol (1980) 0.84
Limited TTP supply affects telomere length regulation in a telomerase-independent fashion. Nucleic Acids Res (2005) 0.82
Inhibitors of DNA precursor metabolism in Dictyostelium discoideum. Antimicrob Agents Chemother (1982) 0.81
Growth-rate-dependent regulation of the expression and inactivation of thymidylate synthase in Saccharomyces cerevisiae. J Bacteriol (1986) 0.80
Identification of Glycolytic Enzyme Polypeptides on the Two-Dimensional Protein Map of Saccharomyces cerevisiae and Application to the Study of Some Wine Yeasts. Appl Environ Microbiol (1985) 0.78
Influence of the nuclear gene tmp3 on the loss of mitochondrial genes in Saccharomyces cerevisiae. Mol Cell Biol (1982) 0.75
Unbiased segregation of yeast chromatids in Saccharomyces cerevisiae. Chromosome Res (2013) 0.75
Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91
The utilization of exogenous pyrimidines and the recycling of uridine-5'-phosphate derivatives in Saccharomyces cerevisiae, as studied by means of mutants affected in pyrimidine uptake and metabolism. Eur J Biochem (1969) 3.94
Three additional genes required for deoxyribonucleic acid synthesis in Saccharomyces cerevisiae. J Bacteriol (1973) 3.82
Thymidine kinase: evidence for its absence from Neurospora crassa and some other micro-organisms, and the relevance of this to the specific labelling of deoxyribonucleic acid. J Gen Microbiol (1968) 3.00
Two chromosomal genes required for killing expression in killer strains of Saccharomyces cerevisiae. Genetics (1976) 2.71
An enzymatic method for the determination of formic acid. J Biol Chem (1957) 2.70
Mitochondrial DNA synthesis in cell cycle mutants of Saccharomyces cerevisiae. Cell (1975) 2.09
Method for decryptification of -glucosidase in yeast with dimethyl sulfoxide. Anal Biochem (1972) 1.92
Evidence for a complex regulating the in vivo activities of early enzymes induced by bacteriophage T4. J Biol Chem (1974) 1.87
Assay of yeast enzymes in situ. A potential tool in regulation studies. Eur J Biochem (1973) 1.83
Yeast cell-cycle mutant cdc21 is a temperature-sensitive thymidylate auxotroph. Mol Gen Genet (1976) 1.59
Defective DNA synthesis in permeabilized yeast mutants. Nat New Biol (1971) 1.25
Isolation and characterization of mutants of Saccharomyces cerevisiae auxotrophic and conditionally auxotrophic for 5'-dTMP. Z Naturforsch C (1975) 1.22
"Thymineless death" in a strain of Saccharomyces cerevisiae auxotrophic for deoxythymidine-5'-monophosphate. Mol Gen Genet (1974) 1.17
An improved method for the preparation of yeast enzymes in situ. Biochem Biophys Res Commun (1975) 1.12
A rapid assay for thymidylate synthetase. Anal Biochem (1966) 1.12
A temperature-sensitive thy mutant blocked in the synthesis of thymidylate synthetase. J Biol Chem (1971) 1.04
Mutants of Saccharomyces cerevisiae that incorporate deoxythymidine 5'-monophosphate into DNA in vivo. Methods Cell Biol (1975) 1.02
Isolation and characterization of mutants of Saccharomyces cerevisiae able to grow after inhibition of dTMP synthesis. Methods Cell Biol (1975) 1.00
Model systems for the study of seven-transmembrane-segment receptors. Annu Rev Biochem (1991) 5.70
Glycosylation and processing of prepro-alpha-factor through the yeast secretory pathway. Cell (1984) 5.53
Isolation of the putative structural gene for the lysine-arginine-cleaving endopeptidase required for processing of yeast prepro-alpha-factor. Cell (1984) 5.26
Yeast alpha factor is processed from a larger precursor polypeptide: the essential role of a membrane-bound dipeptidyl aminopeptidase. Cell (1983) 4.24
Saccharomyces cerevisiae STE6 gene product: a novel pathway for protein export in eukaryotic cells. EMBO J (1989) 4.10
Enzymes required for yeast prohormone processing. Annu Rev Physiol (1988) 4.06
A putative protein kinase overcomes pheromone-induced arrest of cell cycling in S. cerevisiae. Cell (1989) 3.99
An MF alpha 1-SUC2 (alpha-factor-invertase) gene fusion for study of protein localization and gene expression in yeast. Proc Natl Acad Sci U S A (1983) 3.95
Genetic and pharmacological suppression of oncogenic mutations in ras genes of yeast and humans. Science (1989) 3.90
A candidate protein kinase C gene, PKC1, is required for the S. cerevisiae cell cycle. Cell (1990) 3.87
Homing of a DNA endonuclease gene by meiotic gene conversion in Saccharomyces cerevisiae. Nature (1992) 3.77
Intracellular targeting and structural conservation of a prohormone-processing endoprotease. Science (1989) 3.61
Yeast prohormone processing enzyme (KEX2 gene product) is a Ca2+-dependent serine protease. Proc Natl Acad Sci U S A (1989) 3.49
Mot1, a global repressor of RNA polymerase II transcription, inhibits TBP binding to DNA by an ATP-dependent mechanism. Genes Dev (1994) 3.45
The carboxy-terminal segment of the yeast alpha-factor receptor is a regulatory domain. Cell (1988) 3.42
Recovery of S. cerevisiae a cells from G1 arrest by alpha factor pheromone requires endopeptidase action. Cell (1979) 3.23
Isolation of the yeast calmodulin gene: calmodulin is an essential protein. Cell (1986) 3.17
Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro-beta-NGF in vivo. J Cell Biol (1990) 3.03
Yeast has homologs (CNA1 and CNA2 gene products) of mammalian calcineurin, a calmodulin-regulated phosphoprotein phosphatase. Proc Natl Acad Sci U S A (1991) 3.02
Cell interactions and regulation of cell type in the yeast Saccharomyces cerevisiae. Annu Rev Microbiol (1983) 3.00
Protein splicing elements: inteins and exteins--a definition of terms and recommended nomenclature. Nucleic Acids Res (1994) 2.97
Inhibitory and activating functions for MAPK Kss1 in the S. cerevisiae filamentous-growth signalling pathway. Nature (1997) 2.85
RGS proteins and signaling by heterotrimeric G proteins. J Biol Chem (1997) 2.82
Regulatory subunit (CNB1 gene product) of yeast Ca2+/calmodulin-dependent phosphoprotein phosphatases is required for adaptation to pheromone. Mol Cell Biol (1992) 2.80
Cell-cell recognition in Saccharomyces cerevisiae: regulation of mating-specific adhesion. J Bacteriol (1978) 2.76
Direct involvement of phosphatidylinositol 4-phosphate in secretion in the yeast Saccharomyces cerevisiae. J Biol Chem (1999) 2.72
Signaling in the yeast pheromone response pathway: specific and high-affinity interaction of the mitogen-activated protein (MAP) kinases Kss1 and Fus3 with the upstream MAP kinase kinase Ste7. Mol Cell Biol (1996) 2.57
Functional counterparts of mammalian protein kinases PDK1 and SGK in budding yeast. Curr Biol (1999) 2.56
A presumptive helicase (MOT1 gene product) affects gene expression and is required for viability in the yeast Saccharomyces cerevisiae. Mol Cell Biol (1992) 2.56
Hsl7 localizes to a septin ring and serves as an adapter in a regulatory pathway that relieves tyrosine phosphorylation of Cdc28 protein kinase in Saccharomyces cerevisiae. Mol Cell Biol (1999) 2.54
Two novel targets of the MAP kinase Kss1 are negative regulators of invasive growth in the yeast Saccharomyces cerevisiae. Genes Dev (1996) 2.49
The yeast ARD1 gene product is required for repression of cryptic mating-type information at the HML locus. Mol Cell Biol (1987) 2.30
Signal propagation and regulation in the mating pheromone response pathway of the yeast Saccharomyces cerevisiae. Dev Biol (1994) 2.30
Sst2, a negative regulator of pheromone signaling in the yeast Saccharomyces cerevisiae: expression, localization, and genetic interaction and physical association with Gpa1 (the G-protein alpha subunit). Mol Cell Biol (1996) 2.20
A conserved docking site in MEKs mediates high-affinity binding to MAP kinases and cooperates with a scaffold protein to enhance signal transmission. J Biol Chem (2000) 1.96
Yeast homologue of neuronal frequenin is a regulator of phosphatidylinositol-4-OH kinase. Nat Cell Biol (1999) 1.94
Novel yeast protein kinase (YPK1 gene product) is a 40-kilodalton phosphotyrosyl protein associated with protein-tyrosine kinase activity. Mol Cell Biol (1990) 1.93
The STE2 gene product is the ligand-binding component of the alpha-factor receptor of Saccharomyces cerevisiae. J Biol Chem (1988) 1.92
Repression of yeast Ste12 transcription factor by direct binding of unphosphorylated Kss1 MAPK and its regulation by the Ste7 MEK. Genes Dev (1998) 1.92
Ste5 RING-H2 domain: role in Ste4-promoted oligomerization for yeast pheromone signaling. Science (1997) 1.88
The yeast repeated element sigma contains a hormone-inducible promoter. Mol Cell Biol (1987) 1.88
Phosphatidylinositol 4-kinase: gene structure and requirement for yeast cell viability. Science (1993) 1.86
Genetic manipulation of Saccharomyces cerevisiae by use of the LYS2 gene. Mol Cell Biol (1986) 1.84
Differential regulation of transcription: repression by unactivated mitogen-activated protein kinase Kss1 requires the Dig1 and Dig2 proteins. Proc Natl Acad Sci U S A (1998) 1.73
Genetic and biochemical characterization of a phosphatidylinositol-specific phospholipase C in Saccharomyces cerevisiae. Mol Cell Biol (1993) 1.71
Protein-tyrosine kinase activity in Saccharomyces cerevisiae. Science (1986) 1.68
The a-factor transporter (STE6 gene product) and cell polarity in the yeast Saccharomyces cerevisiae. J Cell Biol (1993) 1.67
Solid phase peptide synthesis of alpha-factor, a yeast mating pheromone. Biochem Biophys Res Commun (1977) 1.66
Yeast KEX2 endopeptidase correctly cleaves a neuroendocrine prohormone in mammalian cells. Science (1988) 1.64
Molecular cloning of hormone-responsive genes from the yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1984) 1.59
Identification of tubulin from the yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1978) 1.57
Yeast mating pheromone alpha factor inhibits adenylate cyclase. Proc Natl Acad Sci U S A (1980) 1.57
Expression and purification of the Saccharomyces cerevisiae alpha-factor receptor (Ste2p), a 7-transmembrane-segment G protein-coupled receptor. J Biol Chem (1997) 1.56
Putting it on and taking it off: phosphoprotein phosphatase involvement in cell cycle regulation. Cell (1989) 1.55
A conserved motif at the amino termini of MEKs might mediate high-affinity interaction with the cognate MAPKs. Trends Biochem Sci (1996) 1.54
Identification and characterization of an essential family of inositol polyphosphate 5-phosphatases (INP51, INP52 and INP53 gene products) in the yeast Saccharomyces cerevisiae. Genetics (1998) 1.52
Dynamic localization of the Swe1 regulator Hsl7 during the Saccharomyces cerevisiae cell cycle. Mol Biol Cell (2001) 1.49
Dominant and recessive suppressors that restore glucose transport in a yeast snf3 mutant. Genetics (1991) 1.48
Extracellular suppression allows mating by pheromone-deficient sterile mutants of Saccharomyces cerevisiae. J Bacteriol (1983) 1.46
Mutational activation of the STE5 gene product bypasses the requirement for G protein beta and gamma subunits in the yeast pheromone response pathway. Mol Cell Biol (1994) 1.46
Beta and gamma subunits of a yeast guanine nucleotide-binding protein are not essential for membrane association of the alpha subunit but are required for receptor coupling. Proc Natl Acad Sci U S A (1990) 1.46
A functional prepro-alpha-factor gene in Saccharomyces yeasts can contain three, four, or five repeats of the mature pheromone sequence. Mol Cell Biol (1983) 1.45
Multiple Ca2+/calmodulin-dependent protein kinase genes in a unicellular eukaryote. EMBO J (1991) 1.43
Nucleotidylation, not phosphorylation, is the major source of the phosphotyrosine detected in enteric bacteria. J Bacteriol (1989) 1.42
Mutational analysis of STE5 in the yeast Saccharomyces cerevisiae: application of a differential interaction trap assay for examining protein-protein interactions. Genetics (1997) 1.38
Phosphorylation and localization of Kss1, a MAP kinase of the Saccharomyces cerevisiae pheromone response pathway. Mol Biol Cell (1995) 1.36
G1 cyclin degradation: the PEST motif of yeast Cln2 is necessary, but not sufficient, for rapid protein turnover. Mol Cell Biol (1994) 1.36
Structure and calcium-binding properties of Frq1, a novel calcium sensor in the yeast Saccharomyces cerevisiae. Biochemistry (2000) 1.32
Purification and characterization of VDE, a site-specific endonuclease from the yeast Saccharomyces cerevisiae. J Biol Chem (1993) 1.29
Vertebrate and yeast calmodulin, despite significant sequence divergence, are functionally interchangeable. Proc Natl Acad Sci U S A (1989) 1.29
Control of yeast mating signal transduction by a mammalian beta 2-adrenergic receptor and Gs alpha subunit. Science (1990) 1.28
Mutational analysis suggests that activation of the yeast pheromone response mitogen-activated protein kinase pathway involves conformational changes in the Ste5 scaffold protein. Mol Biol Cell (2000) 1.25
Secretion of peptides and proteins lacking hydrophobic signal sequences: the role of adenosine triphosphate-driven membrane translocators. Endocr Rev (1992) 1.20
VDE endonuclease cleaves Saccharomyces cerevisiae genomic DNA at a single site: physical mapping of the VMA1 gene. Nucleic Acids Res (1992) 1.19
A novel FK506- and rapamycin-binding protein (FPR3 gene product) in the yeast Saccharomyces cerevisiae is a proline rotamase localized to the nucleolus. J Cell Biol (1994) 1.19
Functional expression of human mdr1 in the yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1992) 1.17
Transient gene expression in HEK293 cells: peptone addition posttransfection improves recombinant protein synthesis. Biotechnol Bioeng (2005) 1.17
Overexpression of the yeast MCK1 protein kinase suppresses conditional mutations in centromere-binding protein genes CBF2 and CBF5. Mol Gen Genet (1995) 1.15
Casein kinase II catalyzes tyrosine phosphorylation of the yeast nucleolar immunophilin Fpr3. J Biol Chem (1997) 1.15
Purification and characterization of a soluble phosphatidylinositol 4-kinase from the yeast Saccharomyces cerevisiae. J Biol Chem (1992) 1.12
Saccharomyces cerevisiae STE14 gene is required for COOH-terminal methylation of a-factor mating pheromone. J Biol Chem (1990) 1.10
Mutations in the pho80 gene confer permeability to 5'-mononucleotides in Saccharomyces cerevisiae. Genetics (1982) 1.08
High-throughput screening for drug discovery. Nature (1996) 1.08
An essential function of a phosphoinositide-specific phospholipase C is relieved by inhibition of a cyclin-dependent protein kinase in the yeast Saccharomyces cerevisiae. Genetics (1998) 1.08
Isolation of the yeast calmodulin gene using synthetic oligonucleotide probes. Methods Enzymol (1987) 1.05
Identification and characterization of the CLK1 gene product, a novel CaM kinase-like protein kinase from the yeast Saccharomyces cerevisiae. J Biol Chem (1996) 1.03
Yeast MCK1 protein kinase autophosphorylates at tyrosine and serine but phosphorylates exogenous substrates at serine and threonine. J Biol Chem (1993) 1.03
High affinity interaction of yeast transcriptional regulator, Mot1, with TATA box-binding protein (TBP). J Biol Chem (2001) 1.03
Pheromone action regulates G-protein alpha-subunit myristoylation in the yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1993) 1.03
Purification and enzymic properties of Mot1 ATPase, a regulator of basal transcription in the yeast Saccharomyces cerevisiae. J Biol Chem (2000) 1.02
Complete nucleotide sequence of the gene encoding the regulatory subunit of 3',5'-cyclic AMP-dependent protein kinase from the yeast Saccharomyces cerevisiae. Nucleic Acids Res (1987) 0.98
An essential role for cyclic AMP in growth control: the case for yeast. Cell (1982) 0.96
The PAL1 gene product is a peroxisomal ATP-binding cassette transporter in the yeast Saccharomyces cerevisiae. J Cell Biol (1996) 0.96
Thymidylate synthetase from Saccharomyces cerevisiae. Purification and enzymic properties. J Biol Chem (1981) 0.96
Receptor-G protein signaling in yeast. Annu Rev Physiol (1991) 0.95
The MF alpha 1 gene of Saccharomyces cerevisiae: genetic mapping and mutational analysis of promoter elements. Genetics (1989) 0.93
Adherence to Universal (barrier) Precautions during interventions on critically ill and injured emergency department patients. J Acquir Immune Defic Syndr (1990) 0.93
Aberrant protein phosphorylation at tyrosine is responsible for the growth-inhibitory action of pp60v-src expressed in the yeast Saccharomyces cerevisiae. Mol Biol Cell (1994) 0.92
Yeast mating pheromone activates mammalian gonadotrophs: evolutionary conservation of a reproductive hormone? Science (1982) 0.91