Turbulent fluid shear stress induces vascular endothelial cell turnover in vitro.

PubWeight™: 2.73‹?› | Rank: Top 1%

🔗 View Article (PMC 323241)

Published in Proc Natl Acad Sci U S A on April 01, 1986

Authors

P F Davies, A Remuzzi, E J Gordon, C F Dewey, M A Gimbrone

Articles citing this

Flow-mediated endothelial mechanotransduction. Physiol Rev (1995) 10.13

A tense situation: forcing tumour progression. Nat Rev Cancer (2009) 7.80

Effects of disturbed flow on vascular endothelium: pathophysiological basis and clinical perspectives. Physiol Rev (2011) 5.51

Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress. Proc Natl Acad Sci U S A (1996) 3.93

Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology. Nat Clin Pract Cardiovasc Med (2008) 3.49

Vascular remodeling of the mouse yolk sac requires hemodynamic force. Development (2007) 3.26

Biomechanical activation of vascular endothelium as a determinant of its functional phenotype. Proc Natl Acad Sci U S A (2001) 2.89

Shear stress selectively upregulates intercellular adhesion molecule-1 expression in cultured human vascular endothelial cells. J Clin Invest (1994) 2.35

The role of the glycocalyx in reorganization of the actin cytoskeleton under fluid shear stress: a "bumper-car" model. Proc Natl Acad Sci U S A (2004) 2.05

Molecular mechanism of endothelial growth arrest by laminar shear stress. Proc Natl Acad Sci U S A (2000) 1.83

Theoretical estimates of mechanical properties of the endothelial cell cytoskeleton. Biophys J (1996) 1.79

Spatial and temporal regulation of gap junction connexin43 in vascular endothelial cells exposed to controlled disturbed flows in vitro. Proc Natl Acad Sci U S A (1999) 1.75

A hitchhiker's guide to mechanobiology. Dev Cell (2011) 1.72

The effects of hemodynamic force on embryonic development. Microcirculation (2010) 1.66

Vascular endothelium, hemodynamic forces, and atherogenesis. Am J Pathol (1999) 1.57

Dynamics of neutrophil rolling over stimulated endothelium in vitro. Biophys J (1994) 1.55

The leukocyte response to fluid stress. Proc Natl Acad Sci U S A (1997) 1.53

Flow, NO, and atherogenesis. Proc Natl Acad Sci U S A (2003) 1.51

Cytotoxic mAb from rheumatic carditis recognizes heart valves and laminin. J Clin Invest (2000) 1.46

Autoantibodies against heat shock protein 60 mediate endothelial cytotoxicity. J Clin Invest (1995) 1.45

MicroRNA-23b regulates cyclin-dependent kinase-activating kinase complex through cyclin H repression to modulate endothelial transcription and growth under flow. Arterioscler Thromb Vasc Biol (2014) 1.43

The HDL hypothesis: does high-density lipoprotein protect from atherosclerosis? J Lipid Res (2010) 1.36

In vitro blood-brain barrier models: current and perspective technologies. J Pharm Sci (2011) 1.36

Autonomously vascularized cellular constructs in tissue engineering: opening a new perspective for biomedical science. J Cell Mol Med (2007) 1.31

The atherosusceptible endothelium: endothelial phenotypes in complex haemodynamic shear stress regions in vivo. Cardiovasc Res (2013) 1.30

The role of cellular adaptation to mechanical forces in atherosclerosis. Arterioscler Thromb Vasc Biol (2008) 1.28

Endothelial cell responses to atheroprone flow are driven by two separate flow components: low time-average shear stress and fluid flow reversal. Am J Physiol Heart Circ Physiol (2009) 1.27

High definition live 3D-OCT in vivo: design and evaluation of a 4D OCT engine with 1 GVoxel/s. Biomed Opt Express (2014) 1.26

The role of shear stress in Blood-Brain Barrier endothelial physiology. BMC Neurosci (2011) 1.25

Endothelial Cell Dysfunction and the Pathobiology of Atherosclerosis. Circ Res (2016) 1.20

Biomechanics of the sensor-tissue interface-effects of motion, pressure, and design on sensor performance and the foreign body response-part I: theoretical framework. J Diabetes Sci Technol (2011) 1.18

'Pressure-flow'-triggered intracellular Ca2+ transients in rat cardiac myocytes: possible mechanisms and role of mitochondria. J Physiol (2008) 1.15

Dynamic responses of endothelial cells to changes in blood flow during vascular remodeling of the mouse yolk sac. Development (2013) 1.13

Disturbed blood flow acutely induces activation and apoptosis of the human vascular endothelium. Hypertension (2013) 1.13

Nitric oxide-dependent stimulation of endothelial cell proliferation by sustained high flow. Am J Physiol Heart Circ Physiol (2008) 1.10

The multiparametric effects of hydrodynamic environments on stem cell culture. Tissue Eng Part B Rev (2011) 1.06

Response of cultured endothelial cells to mechanical stimulation. Basic Res Cardiol (1989) 1.06

Variable expression of desmin in rat glomerular epithelial cells. Am J Pathol (1990) 1.03

Acute and chronic exposure to shear stress have opposite effects on endothelial permeability to macromolecules. Am J Physiol Heart Circ Physiol (2010) 1.00

Rheoreceptors in the carotid sinus of dog. Proc Natl Acad Sci U S A (1988) 1.00

Flow-dependent cellular mechanotransduction in atherosclerosis. J Cell Sci (2013) 1.00

GM-CSF contributes to aortic aneurysms resulting from SMAD3 deficiency. J Clin Invest (2013) 0.99

Expression of the bumetanide-sensitive Na-K-Cl cotransporter BSC2 is differentially regulated by fluid mechanical and inflammatory cytokine stimuli in vascular endothelium. J Clin Invest (1997) 0.99

Analysis of haemodynamic disturbance in the atherosclerotic carotid artery using computational fluid dynamics. Eur Radiol (2006) 0.98

Lipid deposition and intimal stress and strain. A study in rats with aortic stenosis. Am J Pathol (1991) 0.98

Animal, in vitro, and ex vivo models of flow-dependent atherosclerosis: role of oxidative stress. Antioxid Redox Signal (2010) 0.97

Role of cellular mechanics in the function and life span of vascular endothelium. Pflugers Arch (2011) 0.96

RNA interference mutant induction in vivo demonstrates the essential nature of trypanosome flagellar function during mammalian infection. Eukaryot Cell (2007) 0.94

The mechanics of development: Models and methods for tissue morphogenesis. Birth Defects Res C Embryo Today (2010) 0.93

Localization of calcium and microfilament changes in mechanically stressed cells. Cell Biophys (1990) 0.93

Molecular mechanisms responsible for the atheroprotective effects of laminar shear stress. Antioxid Redox Signal (2009) 0.91

Vascular endothelial cells minimize the total force on their nuclei. Biophys J (2000) 0.87

Quantitative morphodynamics of endothelial cells within confluent cultures in response to fluid shear stress. Biophys J (2000) 0.87

Direct numerical simulation of transitional flow in a stenosed carotid bifurcation. J Biomech (2008) 0.86

Elevated electrochemical impedance in the endoluminal regions with high shear stress: implication for assessing lipid-rich atherosclerotic lesions. Biosens Bioelectron (2012) 0.86

MEMS thermal sensors to detect changes in heat transfer in the pre-atherosclerotic regions of fat-fed New Zealand white rabbits. Ann Biomed Eng (2011) 0.85

Shear stress regulation of nitric oxide production in uterine and placental artery endothelial cells: experimental studies and hemodynamic models of shear stresses on endothelial cells. Int J Dev Biol (2010) 0.85

Distinct profiles of endothelial gene expression in hyperpermeable regions of the porcine aortic arch and thoracic aorta. Atherosclerosis (2007) 0.85

miR-126 Is Involved in Vascular Remodeling under Laminar Shear Stress. Biomed Res Int (2015) 0.84

Impedance analysis of GPCR-mediated changes in endothelial barrier function: overview and fundamental considerations for stable and reproducible measurements. Pflugers Arch (2014) 0.84

Blood pressure regulation VIII: resistance vessel tone and implications for a pro-atherogenic conduit artery endothelial cell phenotype. Eur J Appl Physiol (2013) 0.84

Real-time assessment of flow reversal in an eccentric arterial stenotic model. J Biomech (2010) 0.84

Experimental insights into flow impingement in cerebral aneurysm by stereoscopic particle image velocimetry: transition from a laminar regime. J R Soc Interface (2013) 0.84

Role of caveolin-1 in the regulation of the vascular shear stress response. J Clin Invest (2006) 0.84

Transcriptional regulation of endothelial dysfunction in atherosclerosis: an epigenetic perspective. J Biomed Res (2013) 0.84

Engineered arterial models to correlate blood flow to tissue biological response. Ann N Y Acad Sci (2012) 0.83

Mechanomics: an emerging field between biology and biomechanics. Protein Cell (2014) 0.83

Interaction between drug delivery vehicles and cells under the effect of shear stress. Biomicrofluidics (2015) 0.83

Effect of Static Pre-stretch Induced Surface Anisotropy on Orientation of Mesenchymal Stem Cells. Cell Mol Bioeng (2014) 0.82

Factors affecting formation and rupture of intracranial saccular aneurysms. Neurosurg Rev (2013) 0.82

Long-range ordered vorticity patterns in living tissue induced by cell division. Nat Commun (2014) 0.82

Hemodynamic Shear Stress and Endothelial Dysfunction in Hemodialysis Access. Open Urol Nephrol J (2014) 0.81

Flow in the early embryonic human heart: a numerical study. Pediatr Cardiol (2003) 0.81

Atrial fibrillation pacing decreases intravascular shear stress in a New Zealand white rabbit model: implications in endothelial function. Biomech Model Mechanobiol (2012) 0.81

Mechanical valve dysfunction in yemen. Heart Views (2010) 0.80

Engineering clinically relevant volumes of vascularized bone. J Cell Mol Med (2015) 0.79

Biomechanical Forces Promote Immune Regulatory Function of Bone Marrow Mesenchymal Stromal Cells. Stem Cells (2017) 0.79

Vascular Adaptation to Exercise in Humans: Role of Hemodynamic Stimuli. Physiol Rev (2017) 0.79

Particle depositions and related hemodynamic parameters in the multiple stenosed right coronary artery. J Clin Med Res (2012) 0.78

Analysis of both pulsatile and streamline blood flow patterns during aerobic and resistance exercise. Eur J Appl Physiol (2012) 0.77

Techniques and assays for the study of angiogenesis. Exp Biol Med (Maywood) (2014) 0.77

Large animal models of cardiovascular disease. Cell Biochem Funct (2016) 0.77

Carotid artery stenosis near a bifurcation investigated by fluid dynamic analyses. Neuroradiol J (2013) 0.77

The effect of noisy flow on endothelial cell mechanotransduction: a computational study. Ann Biomed Eng (2010) 0.76

Transitional Flow in a Cylindrical Flow Chamber for Studies at the Cellular Level. Cardiovasc Eng Technol (2012) 0.76

Physiologically Modeled Pulse Dynamics to Improve Function in In Vitro-Endothelialized Small-Diameter Vascular Grafts. Tissue Eng Part C Methods (2015) 0.75

Fluid Dynamics Appearing during Simulated Microgravity Using Random Positioning Machines. PLoS One (2017) 0.75

Metabolic Imaging of Head and Neck Cancer Organoids. PLoS One (2017) 0.75

Different Effects of Orbital Shear Stress on Vascular Endothelial Cells: Comparison with the Results of In Vivo Study with Rats. Vasc Specialist Int (2015) 0.75

Numerical analysis of the effect of turbulence transition on the hemodynamic parameters in human coronary arteries. Cardiovasc Diagn Ther (2016) 0.75

The importance of velocity acceleration to flow-mediated dilation. Int J Vasc Med (2012) 0.75

Yap/Taz transcriptional activity is essential for vascular regression via Ctgf expression and actin polymerization. PLoS One (2017) 0.75

Computational analysis of fluid flow within a device for applying biaxial strain to cultured cells. J Biomech Eng (2015) 0.75

Axillobifemoral bypass: a brief surgical and historical review. Einstein J Biol Med (2016) 0.75

Ultrasonic Transducer-Guided Electrochemical Impedance Spectroscopy to Assess Lipid-Laden Plaques. Sens Actuators B Chem (2016) 0.75

A method for high-throughput functional imaging of single cells within heterogeneous cell preparations. Sci Rep (2016) 0.75

Heart Valve Biomechanics and Underlying Mechanobiology. Compr Physiol (2016) 0.75

Applying shear stress to endothelial cells in a new perfusion chamber: hydrodynamic analysis. J Artif Organs (2014) 0.75

Mechanotransduction Effects on Endothelial Cell Proliferation via CD31 and VEGFR2: Implications for Immunomagnetic Separation. Biotechnol J (2017) 0.75

Articles cited by this

Carotid bifurcation atherosclerosis. Quantitative correlation of plaque localization with flow velocity profiles and wall shear stress. Circ Res (1983) 4.25

Acute vascular endothelial changes associated with increased blood velocity gradients. Circ Res (1968) 3.77

Atheroma and arterial wall shear. Observation, correlation and proposal of a shear dependent mass transfer mechanism for atherogenesis. Proc R Soc Lond B Biol Sci (1971) 3.70

Mediation of pinocytosis in cultured arterial smooth muscle and endothelial cells by platelet-derived growth factor. J Cell Biol (1978) 2.16

Cell replication in the aortic endothelium: a new method for study of the problem. Lab Invest (1973) 1.99

Influence of hemodynamic forces on vascular endothelial function. In vitro studies of shear stress and pinocytosis in bovine aortic cells. J Clin Invest (1984) 1.77

Apparatus for subjecting living cells to fluid shear stress. Rev Sci Instrum (1982) 1.53

A quantitative study of the localization of atherosclerotic lesions in the rabbit aorta. Atherosclerosis (1976) 1.51

Mitosis patterns in aortic endothelium. Atherosclerosis (1972) 1.43

Flow patterns in the human carotid artery bifurcation. Stroke (1984) 1.35

Relationship between blood flow direction and endothelial cell orientation at arterial branch sites in rabbits and mice. Circ Res (1981) 1.32

Correlation between intimal thickness and fluid shear in human arteries. Atherosclerosis (1981) 1.20

Effects of cytoskeletal disrupting agents on replication of bovine endothelium. J Cell Physiol (1981) 1.19

Wall shear stress distribution in a model canine artery during steady flow. Circ Res (1977) 1.10

Scanning electron microscopy in the evaluation of endothelial integrity of the fatty lesion in atherosclerosis. Atherosclerosis (1976) 1.10

Relationship between low intensity shear stress, aortic histamine formation, and aortic albumin uptake. Exp Mol Pathol (1980) 0.89

Articles by these authors

Endothelial leukocyte adhesion molecule 1: an inducible receptor for neutrophils related to complement regulatory proteins and lectins. Science (1989) 10.70

Identification of an inducible endothelial-leukocyte adhesion molecule. Proc Natl Acad Sci U S A (1987) 10.43

Interleukin 1 acts on cultured human vascular endothelium to increase the adhesion of polymorphonuclear leukocytes, monocytes, and related leukocyte cell lines. J Clin Invest (1985) 8.70

Overlapping patterns of activation of human endothelial cells by interleukin 1, tumor necrosis factor, and immune interferon. J Immunol (1986) 8.22

Culture of vascular endothelium. Prog Hemost Thromb (1976) 7.05

The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling. Cell (1997) 6.34

Human vascular endothelial cells in culture. Growth and DNA synthesis. J Cell Biol (1974) 5.95

Interleukin 1 (IL-1) induces biosynthesis and cell surface expression of procoagulant activity in human vascular endothelial cells. J Exp Med (1984) 5.89

Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: characterization and comparison with the actions of interleukin 1. Proc Natl Acad Sci U S A (1986) 5.83

Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis. Science (1991) 5.76

Two distinct monokines, interleukin 1 and tumor necrosis factor, each independently induce biosynthesis and transient expression of the same antigen on the surface of cultured human vascular endothelial cells. J Immunol (1986) 5.57

Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines. J Clin Invest (1995) 5.09

Ia expression by vascular endothelium is inducible by activated T cells and by human gamma interferon. J Exp Med (1983) 4.92

Immune interferon activates multiple class II major histocompatibility complex genes and the associated invariant chain gene in human endothelial cells and dermal fibroblasts. Proc Natl Acad Sci U S A (1984) 4.43

Tumor dormancy in vivo by prevention of neovascularization. J Exp Med (1972) 4.34

The dynamic response of vascular endothelial cells to fluid shear stress. J Biomech Eng (1981) 4.27

MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under flow conditions. Nature (1999) 4.19

Lymphocytes recognize human vascular endothelial and dermal fibroblast Ia antigens induced by recombinant immune interferon. Nature (1983) 4.16

Tumor growth and neovascularization: an experimental model using the rabbit cornea. J Natl Cancer Inst (1974) 4.05

Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress. Proc Natl Acad Sci U S A (1996) 3.93

Activated macrophages induce vascular proliferation. Nature (1977) 3.74

Induction and detection of a human endothelial activation antigen in vivo. J Exp Med (1986) 3.66

Haemodynamic shear stress activates a K+ current in vascular endothelial cells. Nature (1988) 3.12

Activation of cultured human endothelial cells by recombinant lymphotoxin: comparison with tumor necrosis factor and interleukin 1 species. J Immunol (1987) 3.06

Leukocyte adhesion molecule-1 (LAM-1, L-selectin) interacts with an inducible endothelial cell ligand to support leukocyte adhesion. J Immunol (1991) 3.05

Monocyte rolling, arrest and spreading on IL-4-activated vascular endothelium under flow is mediated via sequential action of L-selectin, beta 1-integrins, and beta 2-integrins. J Cell Biol (1994) 3.02

IL-4 induces adherence of human eosinophils and basophils but not neutrophils to endothelium. Association with expression of VCAM-1. J Immunol (1992) 2.89

Biomechanical activation of vascular endothelium as a determinant of its functional phenotype. Proc Natl Acad Sci U S A (2001) 2.89

A role for smad6 in development and homeostasis of the cardiovascular system. Nat Genet (2000) 2.80

Endothelial-leukocyte adhesion molecule-1-dependent and leukocyte (CD11/CD18)-dependent mechanisms contribute to polymorphonuclear leukocyte adhesion to cytokine-activated human vascular endothelium. J Immunol (1989) 2.80

Cytokine-activated human endothelial monolayers support enhanced neutrophil transmigration via a mechanism involving both endothelial-leukocyte adhesion molecule-1 and intercellular adhesion molecule-1. J Immunol (1991) 2.77

An atherogenic diet rapidly induces VCAM-1, a cytokine-regulatable mononuclear leukocyte adhesion molecule, in rabbit aortic endothelium. Arterioscler Thromb (1993) 2.77

Adhesion of human basophils, eosinophils, and neutrophils to interleukin 1-activated human vascular endothelial cells: contributions of endothelial cell adhesion molecules. J Exp Med (1991) 2.76

Interleukin-1 activation of vascular endothelium. Effects on procoagulant activity and leukocyte adhesion. Am J Pathol (1985) 2.59

Platelet-derived growth factor B chain promoter contains a cis-acting fluid shear-stress-responsive element. Proc Natl Acad Sci U S A (1993) 2.48

Lysophosphatidylcholine, a component of atherogenic lipoproteins, induces mononuclear leukocyte adhesion molecules in cultured human and rabbit arterial endothelial cells. J Clin Invest (1992) 2.45

Human vascular smooth muscle in culture. Growth and ultrastructure. Lab Invest (1975) 2.41

Expression of ephrinB2 identifies a stable genetic difference between arterial and venous vascular smooth muscle as well as endothelial cells, and marks subsets of microvessels at sites of adult neovascularization. Dev Biol (2001) 2.35

Shear stress selectively upregulates intercellular adhesion molecule-1 expression in cultured human vascular endothelial cells. J Clin Invest (1994) 2.35

Sustained diacylglycerol formation from inositol phospholipids in angiotensin II-stimulated vascular smooth muscle cells. J Biol Chem (1986) 2.33

Angiotensin II stimulation of prostaglandin production in cultured human vascular endothelium. Science (1975) 2.24

Hemodynamic forces are complex regulators of endothelial gene expression. FASEB J (1995) 2.23

Functional angiotensin II receptors in cultured vascular smooth muscle cells. J Cell Biol (1982) 2.22

Vascular endothelium responds to fluid shear stress gradients. Arterioscler Thromb (1992) 2.21

Stimulation of nonlymphoid mesenchymal cell proliferation by a macrophage-derived growth factor. J Immunol (1981) 2.18

Preservation of vascular integrity in organs perfused in vitro with a platelet-rich medium. Nature (1969) 2.16

Mediation of pinocytosis in cultured arterial smooth muscle and endothelial cells by platelet-derived growth factor. J Cell Biol (1978) 2.16

Vascular MADs: two novel MAD-related genes selectively inducible by flow in human vascular endothelium. Proc Natl Acad Sci U S A (1997) 2.15

Fine structure of vascular endothelium in culture. J Ultrastruct Res (1975) 2.15

Intravascular IL-8. Inhibitor of polymorphonuclear leukocyte accumulation at sites of acute inflammation. J Immunol (1991) 2.10

Cytokine activation of vascular endothelium. Effects on tissue-type plasminogen activator and type 1 plasminogen activator inhibitor. J Biol Chem (1988) 2.04

Tumor angiogenesis: iris neovascularization at a distance from experimental intraocular tumors. J Natl Cancer Inst (1973) 1.95

Nuclear factor-kappa B interacts functionally with the platelet-derived growth factor B-chain shear-stress response element in vascular endothelial cells exposed to fluid shear stress. J Clin Invest (1995) 1.94

Shear stress-induced reorganization of the surface topography of living endothelial cells imaged by atomic force microscopy. Circ Res (1994) 1.90

Regulation of the fibrinolytic system of cultured human vascular endothelium by interleukin 1. J Clin Invest (1986) 1.89

Leukotriene B4 stimulates polymorphonuclear leukocyte adhesion to cultured vascular endothelial cells. J Clin Invest (1984) 1.88

Expression of Ia-like antigens by human vascular endothelial cells is inducible in vitro: demonstration by monoclonal antibody binding and immunoprecipitation. Proc Natl Acad Sci U S A (1982) 1.87

Leukocyte-endothelial interaction is augmented by high glucose concentrations and hyperglycemia in a NF-kB-dependent fashion. J Clin Invest (1998) 1.87

Theoretical estimates of mechanical properties of the endothelial cell cytoskeleton. Biophys J (1996) 1.79

Gene structure, chromosomal location, and basis for alternative mRNA splicing of the human VCAM1 gene. Proc Natl Acad Sci U S A (1991) 1.79

Rapid displacement of vimentin intermediate filaments in living endothelial cells exposed to flow. Circ Res (2000) 1.77

Simultaneous measurements of actin filament turnover, filament fraction, and monomer diffusion in endothelial cells. Biophys J (1998) 1.77

Influence of hemodynamic forces on vascular endothelial function. In vitro studies of shear stress and pinocytosis in bovine aortic cells. J Clin Invest (1984) 1.77

Consensus conference on best practices in live kidney donation: recommendations to optimize education, access, and care. Am J Transplant (2015) 1.76

Blood flow and vascular gene expression: fluid shear stress as a modulator of endothelial phenotype. Mol Med Today (1999) 1.75

Vascular endothelial cells respond to spatial gradients in fluid shear stress by enhanced activation of transcription factors. Arterioscler Thromb Vasc Biol (1999) 1.75

Spatial and temporal regulation of gap junction connexin43 in vascular endothelial cells exposed to controlled disturbed flows in vitro. Proc Natl Acad Sci U S A (1999) 1.75

Human cytolytic T lymphocyte interactions with vascular endothelium and fibroblasts: role of effector and target cell molecules. J Immunol (1984) 1.75

Nitric oxide synthesis by cultured endothelial cells is modulated by flow conditions. Circ Res (1995) 1.73

Endothelial and leukocyte forms of IL-8. Conversion by thrombin and interactions with neutrophils. J Immunol (1990) 1.69

Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4. J Clin Invest (1998) 1.67

Structure and chromosomal location of the gene for endothelial-leukocyte adhesion molecule 1. J Biol Chem (1991) 1.66

Thrombotic and hemorrhagic complications in patients with mechanical heart valve prosthesis attending an anticoagulation clinic. Thromb Haemost (1993) 1.65

Inducible expression of class II major histocompatibility complex antigens and the immunogenicity of vascular endothelium. Transplantation (1986) 1.64

Vasoconstriction: a new activity for platelet-derived growth factor. Science (1986) 1.61

Stimulation of transcription factors NF kappa B and AP1 in endothelial cells subjected to shear stress. Biochem Biophys Res Commun (1994) 1.61

Fluid shear stress modulates cytosolic free calcium in vascular endothelial cells. Am J Physiol (1992) 1.61

Inducible expression of vascular cell adhesion molecule-1 by vascular smooth muscle cells in vitro and within rabbit atheroma. Am J Pathol (1993) 1.58

N-acetylcysteine potentiates platelet inhibition by endothelium-derived relaxing factor. Circ Res (1989) 1.58

Vascular endothelium, hemodynamic forces, and atherogenesis. Am J Pathol (1999) 1.57

Phorbol ester and 1-oleoyl-2-acetylglycerol inhibit angiotensin activation of phospholipase C in cultured vascular smooth muscle cells. J Biol Chem (1985) 1.57

Rolling and adhesion of human tumor cells on vascular endothelium under physiological flow conditions. J Clin Invest (1993) 1.56

Adhesion of memory lymphocytes to vascular cell adhesion molecule-1-transduced human vascular endothelial cells under simulated physiological flow conditions in vitro. Circ Res (1996) 1.55

Subcellular distribution of shear stress at the surface of flow-aligned and nonaligned endothelial monolayers. Am J Physiol (1995) 1.55

Factors influencing the expression of stress fibers in vascular endothelial cells in situ. J Cell Biol (1983) 1.54

Apparatus for subjecting living cells to fluid shear stress. Rev Sci Instrum (1982) 1.53

Shear stress gradients remodel endothelial monolayers in vitro via a cell proliferation-migration-loss cycle. Arterioscler Thromb Vasc Biol (1997) 1.52