Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis.

PubWeight™: 5.76‹?› | Rank: Top 1%

🔗 View Article (PMID 1990440)

Published in Science on February 15, 1991

Authors

M I Cybulsky1, M A Gimbrone

Author Affiliations

1: Department of Pathology, Brigham and Women's Hospital, Boston, MA.

Articles citing this

(truncated to the top 100)

Flow-mediated endothelial mechanotransduction. Physiol Rev (1995) 10.13

Conditional vascular cell adhesion molecule 1 deletion in mice: impaired lymphocyte migration to bone marrow. J Exp Med (2001) 5.97

Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines. J Clin Invest (1995) 5.09

A major role for VCAM-1, but not ICAM-1, in early atherosclerosis. J Clin Invest (2001) 4.98

Expression of monocyte chemoattractant protein 1 in macrophage-rich areas of human and rabbit atherosclerotic lesions. Proc Natl Acad Sci U S A (1991) 4.56

Inflammation in atherosclerosis. Arterioscler Thromb Vasc Biol (2012) 4.52

Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress. Proc Natl Acad Sci U S A (1996) 3.93

T lymphocytes from human atherosclerotic plaques recognize oxidized low density lipoprotein. Proc Natl Acad Sci U S A (1995) 3.54

NF-kappaB: pivotal mediator or innocent bystander in atherogenesis? J Clin Invest (2001) 3.34

Vascular and inflammatory stresses mediate atherosclerosis via RAGE and its ligands in apoE-/- mice. J Clin Invest (2008) 3.11

Functional analysis of the human vascular cell adhesion molecule 1 promoter. J Exp Med (1992) 3.03

Monocyte rolling, arrest and spreading on IL-4-activated vascular endothelium under flow is mediated via sequential action of L-selectin, beta 1-integrins, and beta 2-integrins. J Cell Biol (1994) 3.02

Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells. J Clin Invest (1993) 2.97

Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion. J Clin Invest (1996) 2.96

Vascular cell adhesion molecule-1 is expressed in human coronary atherosclerotic plaques. Implications for the mode of progression of advanced coronary atherosclerosis. J Clin Invest (1993) 2.89

Advanced glycation endproducts interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice. A potential mechanism for the accelerated vasculopathy of diabetes. J Clin Invest (1995) 2.80

The combined role of P- and E-selectins in atherosclerosis. J Clin Invest (1998) 2.53

Lysophosphatidylcholine, a component of atherogenic lipoproteins, induces mononuclear leukocyte adhesion molecules in cultured human and rabbit arterial endothelial cells. J Clin Invest (1992) 2.45

Telomere length and replicative aging in human vascular tissues. Proc Natl Acad Sci U S A (1995) 2.40

Shear stress selectively upregulates intercellular adhesion molecule-1 expression in cultured human vascular endothelial cells. J Clin Invest (1994) 2.35

Monocyte-endothelial cell interactions in the development of atherosclerosis. Trends Cardiovasc Med (2008) 2.22

Macrophage colony-stimulating factor gene expression in vascular cells and in experimental and human atherosclerosis. Am J Pathol (1992) 2.19

Expression of intercellular adhesion molecule-1 in atherosclerotic plaques. Am J Pathol (1992) 2.12

Endothelial interferon regulatory factor 1 cooperates with NF-kappa B as a transcriptional activator of vascular cell adhesion molecule 1. Mol Cell Biol (1995) 2.12

PPARalpha activators inhibit cytokine-induced vascular cell adhesion molecule-1 expression in human endothelial cells. Circulation (1999) 2.02

CD1d-dependent activation of NKT cells aggravates atherosclerosis. J Exp Med (2004) 1.80

Gene structure, chromosomal location, and basis for alternative mRNA splicing of the human VCAM1 gene. Proc Natl Acad Sci U S A (1991) 1.79

MRI of carotid atherosclerosis: clinical implications and future directions. Nat Rev Cardiol (2010) 1.78

Increased type 1 plasminogen activator inhibitor gene expression in atherosclerotic human arteries. Proc Natl Acad Sci U S A (1992) 1.76

Adhesion molecules on the endothelium and mononuclear cells in human atherosclerotic lesions. Am J Pathol (1992) 1.66

Role of beta 1 and beta 2 integrins in the adhesion of human CD34hi stem cells to bone marrow stroma. J Clin Invest (1992) 1.65

Molecular imaging in atherosclerosis, thrombosis, and vascular inflammation. Arterioscler Thromb Vasc Biol (2009) 1.65

Absence of P-selectin delays fatty streak formation in mice. J Clin Invest (1997) 1.63

Differential regulation of vascular cell adhesion molecule 1 gene expression by specific NF-kappa B subunits in endothelial and epithelial cells. Mol Cell Biol (1993) 1.62

Neonatally induced inactivation of the vascular cell adhesion molecule 1 gene impairs B cell localization and T cell-dependent humoral immune response. J Exp Med (2001) 1.62

In vivo imaging of molecularly targeted phage. Neoplasia (2006) 1.59

Inducible expression of vascular cell adhesion molecule-1 by vascular smooth muscle cells in vitro and within rabbit atheroma. Am J Pathol (1993) 1.58

Adenovirus receptors. J Virol (2005) 1.55

Structurally similar oxidized phospholipids differentially regulate endothelial binding of monocytes and neutrophils. Proc Natl Acad Sci U S A (1999) 1.53

Arsenic exposure at low-to-moderate levels and skin lesions, arsenic metabolism, neurological functions, and biomarkers for respiratory and cardiovascular diseases: review of recent findings from the Health Effects of Arsenic Longitudinal Study (HEALS) in Bangladesh. Toxicol Appl Pharmacol (2009) 1.51

Modification of high density lipoprotein by myeloperoxidase generates a pro-inflammatory particle. J Biol Chem (2009) 1.51

Leukocyte-inspired biodegradable particles that selectively and avidly adhere to inflamed endothelium in vitro and in vivo. Proc Natl Acad Sci U S A (2003) 1.48

Inflammatory processes in cardiovascular disease: a route to targeted therapies. Nat Rev Cardiol (2016) 1.46

Clinical correlates, heritability, and genetic linkage of circulating CD40 ligand in the Framingham Offspring Study. Am Heart J (2008) 1.45

The protective effect of A20 on atherosclerosis in apolipoprotein E-deficient mice is associated with reduced expression of NF-kappaB target genes. Proc Natl Acad Sci U S A (2007) 1.45

Peptide-based probes for targeted molecular imaging. Biochemistry (2010) 1.43

Residues within a conserved amino acid motif of domains 1 and 4 of VCAM-1 are required for binding to VLA-4. J Cell Biol (1994) 1.43

Interleukin 4 or oncostatin M induces a prolonged increase in P-selectin mRNA and protein in human endothelial cells. J Exp Med (1996) 1.43

Increase in the adhesion molecule P-selectin in endothelium overlying atherosclerotic plaques. Coexpression with intercellular adhesion molecule-1. Am J Pathol (1994) 1.42

Innate and adaptive immunity in atherosclerosis. Semin Immunopathol (2009) 1.40

Lymphocyte adhesion through very late antigen 4: evidence for a novel binding site in the alternatively spliced domain of vascular cell adhesion molecule 1 and an additional alpha 4 integrin counter-receptor on stimulated endothelium. J Exp Med (1992) 1.38

Biomechanical activation: an emerging paradigm in endothelial adhesion biology. J Clin Invest (1997) 1.38

CD11c/CD18 expression is upregulated on blood monocytes during hypertriglyceridemia and enhances adhesion to vascular cell adhesion molecule-1. Arterioscler Thromb Vasc Biol (2010) 1.37

Increased expression of heat shock protein 65 coincides with a population of infiltrating T lymphocytes in atherosclerotic lesions of rabbits specifically responding to heat shock protein 65. J Clin Invest (1993) 1.36

Alternative splicing of human VCAM-1 in activated vascular endothelium. Am J Pathol (1991) 1.35

Effects of 17beta-estradiol on cytokine-induced endothelial cell adhesion molecule expression. J Clin Invest (1996) 1.35

Monocyte adhesion to activated aortic endothelium: role of L-selectin and heparan sulfate proteoglycans. J Cell Biol (1997) 1.32

Flow dynamics, binding and detachment of spherical carriers targeted to ICAM-1 on endothelial cells. Biorheology (2009) 1.32

Identification of putative ligand-binding sites of the integrin alpha 4 beta 1 (VLA-4, CD49d/CD29) Biochem J (1995) 1.32

Advanced glycation endproducts promote adhesion molecule (VCAM-1, ICAM-1) expression and atheroma formation in normal rabbits. Mol Med (1995) 1.31

VCAM-1 expression in adult hematopoietic and nonhematopoietic cells is controlled by tissue-inductive signals and reflects their developmental origin. Blood (2005) 1.30

VCAM-1 is critical in atherosclerosis. J Clin Invest (2001) 1.30

Activated endothelium binds lymphocytes through a novel binding site in the alternately spliced domain of vascular cell adhesion molecule-1. J Exp Med (1992) 1.30

Molecular imaging of atherosclerosis for improving diagnostic and therapeutic development. Circ Res (2012) 1.29

Interleukin-13 protects from atherosclerosis and modulates plaque composition by skewing the macrophage phenotype. EMBO Mol Med (2012) 1.28

P2 receptors: new potential players in atherosclerosis. Br J Pharmacol (2002) 1.27

Perlecan is required to inhibit thrombosis after deep vascular injury and contributes to endothelial cell-mediated inhibition of intimal hyperplasia. Proc Natl Acad Sci U S A (2000) 1.25

Exogenous Molecular Probes for Targeted Imaging in Cancer: Focus on Multi-modal Imaging. Cancers (Basel) (2010) 1.24

Adenovirus-mediated gene transfer into normal rabbit arteries results in prolonged vascular cell activation, inflammation, and neointimal hyperplasia. J Clin Invest (1995) 1.23

Arrangement of domains, and amino acid residues required for binding of vascular cell adhesion molecule-1 to its counter-receptor VLA-4 (alpha 4 beta 1). J Cell Biol (1994) 1.23

Identification of CAD candidate genes in GWAS loci and their expression in vascular cells. J Lipid Res (2013) 1.23

Endothelial Cell Dysfunction and the Pathobiology of Atherosclerosis. Circ Res (2016) 1.20

Cyclophilin A is an inflammatory mediator that promotes atherosclerosis in apolipoprotein E-deficient mice. J Exp Med (2010) 1.18

Regulation of smooth muscle cell scavenger receptor expression in vivo by atherogenic diets and in vitro by cytokines. J Clin Invest (1995) 1.17

Extravasation of leukocytes in comparison to tumor cells. Cell Commun Signal (2008) 1.16

Vascular cell adhesion molecule-1 and smooth muscle cell activation during atherogenesis. J Clin Invest (1993) 1.16

Regulation of endothelial cell adhesion molecule expression by mast cells, macrophages, and neutrophils. PLoS One (2011) 1.15

Rous-Whipple Award Lecture. Atherosclerosis: a defense mechanism gone awry. Am J Pathol (1993) 1.15

Association between arsenic exposure from drinking water and plasma levels of soluble cell adhesion molecules. Environ Health Perspect (2007) 1.15

Minimally modified low-density lipoprotein induces monocyte adhesion to endothelial connecting segment-1 by activating beta1 integrin. J Clin Invest (1999) 1.14

Monocyte adhesion to endothelium in simian immunodeficiency virus-induced AIDS encephalitis is mediated by vascular cell adhesion molecule-1/alpha 4 beta 1 integrin interactions. Am J Pathol (1994) 1.14

Immunotargeting of liposomes to activated vascular endothelial cells: a strategy for site-selective delivery in the cardiovascular system. Proc Natl Acad Sci U S A (1997) 1.14

In vivo interrogation of the molecular display of atherosclerotic lesion surfaces. Am J Pathol (2003) 1.13

Structural specializations of α(4)β(7), an integrin that mediates rolling adhesion. J Cell Biol (2012) 1.13

Rabbit models for the study of human atherosclerosis: from pathophysiological mechanisms to translational medicine. Pharmacol Ther (2014) 1.12

Tissue engineered perivascular endothelial cell implants regulate vascular injury. Proc Natl Acad Sci U S A (1995) 1.12

Induction of experimental bone metastasis in mice by transfection of integrin alpha 4 beta 1 into tumor cells. Am J Pathol (1996) 1.12

Serum lipid profiles are associated with disability and MRI outcomes in multiple sclerosis. J Neuroinflammation (2011) 1.11

Tumor cell surface alpha 4 beta 1 integrin mediates adhesion to vascular endothelium: demonstration of an interaction with the N-terminal domains of INCAM-110/VCAM-1. Cell Regul (1991) 1.10

Immune and inflammatory mechanisms in the development of atherosclerosis. Br Heart J (1993) 1.09

Gene expression profile in interleukin-4-stimulated human vascular endothelial cells. Mol Med (2004) 1.09

Magnolol attenuates VCAM-1 expression in vitro in TNF-alpha-treated human aortic endothelial cells and in vivo in the aorta of cholesterol-fed rabbits. Br J Pharmacol (2002) 1.08

An approach to molecular imaging of atherosclerosis, thrombosis, and vascular inflammation using microparticles of iron oxide. Atherosclerosis (2009) 1.08

Long-chain n-3 polyunsaturated fatty acids: new insights into mechanisms relating to inflammation and coronary heart disease. Br J Pharmacol (2009) 1.07

Endothelial dysfunction in diabetes: multiple targets for treatment. Pflugers Arch (2010) 1.07

Increased ferritin gene expression in atherosclerotic lesions. J Clin Invest (1996) 1.07

High-affinity self-reactive human antibodies by design and selection: targeting the integrin ligand binding site. Proc Natl Acad Sci U S A (1993) 1.06

Rosuvastatin, inflammation, C-reactive protein, JUPITER, and primary prevention of cardiovascular disease--a perspective. Drug Des Devel Ther (2010) 1.06

Mutation of putative divalent cation sites in the alpha 4 subunit of the integrin VLA-4: distinct effects on adhesion to CS1/fibronectin, VCAM-1, and invasin. J Cell Biol (1993) 1.06

Integrin-based therapeutics: biological basis, clinical use and new drugs. Nat Rev Drug Discov (2016) 1.06

Articles by these authors

Endothelial leukocyte adhesion molecule 1: an inducible receptor for neutrophils related to complement regulatory proteins and lectins. Science (1989) 10.70

Identification of an inducible endothelial-leukocyte adhesion molecule. Proc Natl Acad Sci U S A (1987) 10.43

Interleukin 1 acts on cultured human vascular endothelium to increase the adhesion of polymorphonuclear leukocytes, monocytes, and related leukocyte cell lines. J Clin Invest (1985) 8.70

Overlapping patterns of activation of human endothelial cells by interleukin 1, tumor necrosis factor, and immune interferon. J Immunol (1986) 8.22

Culture of vascular endothelium. Prog Hemost Thromb (1976) 7.05

The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling. Cell (1997) 6.34

Human vascular endothelial cells in culture. Growth and DNA synthesis. J Cell Biol (1974) 5.95

Interleukin 1 (IL-1) induces biosynthesis and cell surface expression of procoagulant activity in human vascular endothelial cells. J Exp Med (1984) 5.89

Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: characterization and comparison with the actions of interleukin 1. Proc Natl Acad Sci U S A (1986) 5.83

Two distinct monokines, interleukin 1 and tumor necrosis factor, each independently induce biosynthesis and transient expression of the same antigen on the surface of cultured human vascular endothelial cells. J Immunol (1986) 5.57

Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines. J Clin Invest (1995) 5.09

Ia expression by vascular endothelium is inducible by activated T cells and by human gamma interferon. J Exp Med (1983) 4.92

Immune interferon activates multiple class II major histocompatibility complex genes and the associated invariant chain gene in human endothelial cells and dermal fibroblasts. Proc Natl Acad Sci U S A (1984) 4.43

Tumor dormancy in vivo by prevention of neovascularization. J Exp Med (1972) 4.34

The dynamic response of vascular endothelial cells to fluid shear stress. J Biomech Eng (1981) 4.27

MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under flow conditions. Nature (1999) 4.19

Lymphocytes recognize human vascular endothelial and dermal fibroblast Ia antigens induced by recombinant immune interferon. Nature (1983) 4.16

Tumor growth and neovascularization: an experimental model using the rabbit cornea. J Natl Cancer Inst (1974) 4.05

Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress. Proc Natl Acad Sci U S A (1996) 3.93

Activated macrophages induce vascular proliferation. Nature (1977) 3.74

Induction and detection of a human endothelial activation antigen in vivo. J Exp Med (1986) 3.66

Activation of cultured human endothelial cells by recombinant lymphotoxin: comparison with tumor necrosis factor and interleukin 1 species. J Immunol (1987) 3.06

Leukocyte adhesion molecule-1 (LAM-1, L-selectin) interacts with an inducible endothelial cell ligand to support leukocyte adhesion. J Immunol (1991) 3.05

Monocyte rolling, arrest and spreading on IL-4-activated vascular endothelium under flow is mediated via sequential action of L-selectin, beta 1-integrins, and beta 2-integrins. J Cell Biol (1994) 3.02

IL-4 induces adherence of human eosinophils and basophils but not neutrophils to endothelium. Association with expression of VCAM-1. J Immunol (1992) 2.89

Biomechanical activation of vascular endothelium as a determinant of its functional phenotype. Proc Natl Acad Sci U S A (2001) 2.89

A role for smad6 in development and homeostasis of the cardiovascular system. Nat Genet (2000) 2.80

Endothelial-leukocyte adhesion molecule-1-dependent and leukocyte (CD11/CD18)-dependent mechanisms contribute to polymorphonuclear leukocyte adhesion to cytokine-activated human vascular endothelium. J Immunol (1989) 2.80

Cytokine-activated human endothelial monolayers support enhanced neutrophil transmigration via a mechanism involving both endothelial-leukocyte adhesion molecule-1 and intercellular adhesion molecule-1. J Immunol (1991) 2.77

An atherogenic diet rapidly induces VCAM-1, a cytokine-regulatable mononuclear leukocyte adhesion molecule, in rabbit aortic endothelium. Arterioscler Thromb (1993) 2.77

Adhesion of human basophils, eosinophils, and neutrophils to interleukin 1-activated human vascular endothelial cells: contributions of endothelial cell adhesion molecules. J Exp Med (1991) 2.76

Turbulent fluid shear stress induces vascular endothelial cell turnover in vitro. Proc Natl Acad Sci U S A (1986) 2.73

Interleukin-1 activation of vascular endothelium. Effects on procoagulant activity and leukocyte adhesion. Am J Pathol (1985) 2.59

Platelet-derived growth factor B chain promoter contains a cis-acting fluid shear-stress-responsive element. Proc Natl Acad Sci U S A (1993) 2.48

Lysophosphatidylcholine, a component of atherogenic lipoproteins, induces mononuclear leukocyte adhesion molecules in cultured human and rabbit arterial endothelial cells. J Clin Invest (1992) 2.45

Human vascular smooth muscle in culture. Growth and ultrastructure. Lab Invest (1975) 2.41

Expression of ephrinB2 identifies a stable genetic difference between arterial and venous vascular smooth muscle as well as endothelial cells, and marks subsets of microvessels at sites of adult neovascularization. Dev Biol (2001) 2.35

Shear stress selectively upregulates intercellular adhesion molecule-1 expression in cultured human vascular endothelial cells. J Clin Invest (1994) 2.35

Sustained diacylglycerol formation from inositol phospholipids in angiotensin II-stimulated vascular smooth muscle cells. J Biol Chem (1986) 2.33

Angiotensin II stimulation of prostaglandin production in cultured human vascular endothelium. Science (1975) 2.24

Hemodynamic forces are complex regulators of endothelial gene expression. FASEB J (1995) 2.23

Functional angiotensin II receptors in cultured vascular smooth muscle cells. J Cell Biol (1982) 2.22

Vascular endothelium responds to fluid shear stress gradients. Arterioscler Thromb (1992) 2.21

Stimulation of nonlymphoid mesenchymal cell proliferation by a macrophage-derived growth factor. J Immunol (1981) 2.18

Preservation of vascular integrity in organs perfused in vitro with a platelet-rich medium. Nature (1969) 2.16

Vascular MADs: two novel MAD-related genes selectively inducible by flow in human vascular endothelium. Proc Natl Acad Sci U S A (1997) 2.15

Fine structure of vascular endothelium in culture. J Ultrastruct Res (1975) 2.15

Intravascular IL-8. Inhibitor of polymorphonuclear leukocyte accumulation at sites of acute inflammation. J Immunol (1991) 2.10

Cytokine activation of vascular endothelium. Effects on tissue-type plasminogen activator and type 1 plasminogen activator inhibitor. J Biol Chem (1988) 2.04

Tumor angiogenesis: iris neovascularization at a distance from experimental intraocular tumors. J Natl Cancer Inst (1973) 1.95

Nuclear factor-kappa B interacts functionally with the platelet-derived growth factor B-chain shear-stress response element in vascular endothelial cells exposed to fluid shear stress. J Clin Invest (1995) 1.94

Regulation of the fibrinolytic system of cultured human vascular endothelium by interleukin 1. J Clin Invest (1986) 1.89

Leukotriene B4 stimulates polymorphonuclear leukocyte adhesion to cultured vascular endothelial cells. J Clin Invest (1984) 1.88

Expression of Ia-like antigens by human vascular endothelial cells is inducible in vitro: demonstration by monoclonal antibody binding and immunoprecipitation. Proc Natl Acad Sci U S A (1982) 1.87

Gene structure, chromosomal location, and basis for alternative mRNA splicing of the human VCAM1 gene. Proc Natl Acad Sci U S A (1991) 1.79

Influence of hemodynamic forces on vascular endothelial function. In vitro studies of shear stress and pinocytosis in bovine aortic cells. J Clin Invest (1984) 1.77

Blood flow and vascular gene expression: fluid shear stress as a modulator of endothelial phenotype. Mol Med Today (1999) 1.75

Vascular endothelial cells respond to spatial gradients in fluid shear stress by enhanced activation of transcription factors. Arterioscler Thromb Vasc Biol (1999) 1.75

Human cytolytic T lymphocyte interactions with vascular endothelium and fibroblasts: role of effector and target cell molecules. J Immunol (1984) 1.75

Endothelial and leukocyte forms of IL-8. Conversion by thrombin and interactions with neutrophils. J Immunol (1990) 1.69

Structure and chromosomal location of the gene for endothelial-leukocyte adhesion molecule 1. J Biol Chem (1991) 1.66

Inducible expression of class II major histocompatibility complex antigens and the immunogenicity of vascular endothelium. Transplantation (1986) 1.64

Fluid shear stress modulates cytosolic free calcium in vascular endothelial cells. Am J Physiol (1992) 1.61

Vasoconstriction: a new activity for platelet-derived growth factor. Science (1986) 1.61

Inducible expression of vascular cell adhesion molecule-1 by vascular smooth muscle cells in vitro and within rabbit atheroma. Am J Pathol (1993) 1.58

Vascular endothelium, hemodynamic forces, and atherogenesis. Am J Pathol (1999) 1.57

Phorbol ester and 1-oleoyl-2-acetylglycerol inhibit angiotensin activation of phospholipase C in cultured vascular smooth muscle cells. J Biol Chem (1985) 1.57

Adhesion of memory lymphocytes to vascular cell adhesion molecule-1-transduced human vascular endothelial cells under simulated physiological flow conditions in vitro. Circ Res (1996) 1.55

Factors influencing the expression of stress fibers in vascular endothelial cells in situ. J Cell Biol (1983) 1.54

Apparatus for subjecting living cells to fluid shear stress. Rev Sci Instrum (1982) 1.53

Shear stress gradients remodel endothelial monolayers in vitro via a cell proliferation-migration-loss cycle. Arterioscler Thromb Vasc Biol (1997) 1.52

Monocyte attachment to activated human vascular endothelium in vitro is mediated by leukocyte adhesion molecule-1 (L-selectin) under nonstatic conditions. J Exp Med (1992) 1.52

Vascular endothelium as a regulator of granulopoiesis: production of colony-stimulating activity by cultured human endothelial cells. Blood (1980) 1.51

Induction of an activation antigen on postcapillary venular endothelium in human skin organ culture. J Immunol (1987) 1.44

Plasmalemmal proteins of cultured vascular endothelial cells exhibit apical-basal polarity: analysis by surface-selective iodination. J Cell Biol (1986) 1.44

Cultured human endothelial cells express platelet-derived growth factor A chain. Am J Pathol (1987) 1.42

Lysophosphatidylcholine transcriptionally induces growth factor gene expression in cultured human endothelial cells. J Clin Invest (1994) 1.42

Cellular migration and replication in endothelial regeneration: a study using irradiated endothelial cultures. Lab Invest (1977) 1.42

Neutrophil-mediated damage to human vascular endothelium. Role of cytokine activation. Am J Pathol (1993) 1.41

CREB binding protein is a required coactivator for Smad-dependent, transforming growth factor beta transcriptional responses in endothelial cells. Proc Natl Acad Sci U S A (1998) 1.39

Interleukin-8 induces changes in human neutrophil actin conformation and distribution: relationship to inhibition of adhesion to cytokine-activated endothelium. J Leukoc Biol (1992) 1.39

The omega-3 fatty acid docosahexaenoate reduces cytokine-induced expression of proatherogenic and proinflammatory proteins in human endothelial cells. Arterioscler Thromb (1994) 1.39

Alternative splicing of human VCAM-1 in activated vascular endothelium. Am J Pathol (1991) 1.35

Leukocyte adhesion to vascular endothelium induces E-selectin linkage to the actin cytoskeleton. J Cell Biol (1996) 1.35

Studies on the interaction between GP-18-0-deficient neutrophils and vascular endothelium. Blood (1982) 1.34

Transformation of cultured human vascular endothelium by SV40 DNA. Cell (1976) 1.32

Angiotensin II-stimulated Na+/H+ exchange in cultured vascular smooth muscle cells. Evidence for protein kinase C-dependent and -independent pathways. J Biol Chem (1987) 1.31

Egr-1 is activated in endothelial cells exposed to fluid shear stress and interacts with a novel shear-stress-response element in the PDGF A-chain promoter. Arterioscler Thromb Vasc Biol (1997) 1.30

Endothelial activation during interleukin 2 immunotherapy. A possible mechanism for the vascular leak syndrome. J Immunol (1988) 1.30

Inducible endothelial functions in inflammation and coagulation. Semin Thromb Hemost (1987) 1.29

Orientation of endothelial cells in shear fields in vitro. Biorheology (1984) 1.28

In vitro inhibitory effect of IL-8 and other chemoattractants on neutrophil-endothelial adhesive interactions. J Immunol (1992) 1.26

Heterogeneity of myosin antigenic expression in vascular smooth muscle in vivo. Lab Invest (1984) 1.26

Intravenous interleukin-8 inhibits granulocyte emigration from rabbit mesenteric venules without altering L-selectin expression or leukocyte rolling. J Immunol (1993) 1.24

Regulation by angiotensin II of its receptors in resistance blood vessels. Nature (1980) 1.24

Angiotensin increases inositol trisphosphate and calcium in vascular smooth muscle. Hypertension (1985) 1.24

Arachidonic acid metabolism and the adhesion of human polymorphonuclear leukocytes to cultured vascular endothelial cells. Blood (1983) 1.23

Early agonist-mediated ionic events in cultured vascular smooth muscle cells. Calcium mobilization is associated with intracellular acidification. J Biol Chem (1987) 1.22

MEKK-1, a component of the stress (stress-activated protein kinase/c-Jun N-terminal kinase) pathway, can selectively activate Smad2-mediated transcriptional activation in endothelial cells. J Biol Chem (1999) 1.22