Published in J Biol Chem on March 25, 1986
Macrophage colony-stimulating factor (rM-CSF) stimulates pinocytosis in bone marrow-derived macrophages. J Exp Med (1989) 2.74
Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells. J Leukoc Biol (2010) 2.71
Ligand and protein kinase C downmodulate the colony-stimulating factor 1 receptor by independent mechanisms. Mol Cell Biol (1989) 2.12
Hematopoietic growth factors. J Clin Invest (1987) 2.11
Macrophages specifically regulate the concentration of their own growth factor in the circulation. Proc Natl Acad Sci U S A (1987) 1.82
Ligand-induced tyrosine kinase activity of the colony-stimulating factor 1 receptor in a murine macrophage cell line. Mol Cell Biol (1988) 1.80
Expression of the human c-fms proto-oncogene product (colony-stimulating factor-1 receptor) on peripheral blood mononuclear cells and choriocarcinoma cell lines. J Clin Invest (1986) 1.77
Synthesis of membrane-bound colony-stimulating factor 1 (CSF-1) and downmodulation of CSF-1 receptors in NIH 3T3 cells transformed by cotransfection of the human CSF-1 and c-fms (CSF-1 receptor) genes. Mol Cell Biol (1987) 1.71
Gene expression analysis of macrophages that facilitate tumor invasion supports a role for Wnt-signaling in mediating their activity in primary mammary tumors. J Immunol (2009) 1.64
A point mutation at tyrosine-809 in the human colony-stimulating factor 1 receptor impairs mitogenesis without abrogating tyrosine kinase activity, association with phosphatidylinositol 3-kinase, or induction of c-fos and junB genes. Proc Natl Acad Sci U S A (1990) 1.58
Colony stimulating factor-1 (CSF-1) stimulates temperature dependent phosphorylation and activation of the RAF-1 proto-oncogene product. EMBO J (1990) 1.55
Identification and subcellular localization of proteins that are rapidly phosphorylated in tyrosine in response to colony-stimulating factor 1. Proc Natl Acad Sci U S A (1988) 1.51
Purification of the colony-stimulating factor 1 receptor and demonstration of its tyrosine kinase activity. Proc Natl Acad Sci U S A (1987) 1.45
Expression of colony-stimulating factor 1 receptor during prostate development and prostate cancer progression. Proc Natl Acad Sci U S A (2002) 1.40
Role of dimerization and modification of the CSF-1 receptor in its activation and internalization during the CSF-1 response. EMBO J (1991) 1.38
The role of kinase activity and the kinase insert region in ligand-induced internalization and degradation of the c-fms protein. EMBO J (1991) 1.38
The role of G proteins in transmembrane signalling. Biochem J (1990) 1.34
Macrophage-colony-stimulating factor (CSF-1) induces proliferation, chemotaxis, and reversible monocytic differentiation in myeloid progenitor cells transfected with the human c-fms/CSF-1 receptor cDNA. Proc Natl Acad Sci U S A (1990) 1.31
Comparative effects in vivo of recombinant murine interleukin 3, natural murine colony-stimulating factor-1, and recombinant murine granulocyte-macrophage colony-stimulating factor on myelopoiesis in mice. J Clin Invest (1987) 1.14
Macrophage production during murine listeriosis: colony-stimulating factor 1 (CSF-1) and CSF-1-binding cells in genetically resistant and susceptible mice. Infect Immun (1988) 1.12
Ligand-induced phosphorylation of the colony-stimulating factor 1 receptor can occur through an intermolecular reaction that triggers receptor down modulation. Mol Cell Biol (1990) 1.11
CSF-1 receptor signaling in myeloid cells. Cold Spring Harb Perspect Biol (2014) 1.10
Macrophage colony stimulating factor activates phosphatidylcholine hydrolysis by cytoplasmic phospholipase A2. EMBO J (1992) 1.06
Detection of transcripts for the receptor for macrophage colony-stimulating factor, c-fms, in murine osteoclasts. Proc Natl Acad Sci U S A (1992) 1.05
Efficient translocation of positively charged residues of M13 procoat protein across the membrane excludes electrophoresis as the primary force for membrane insertion. EMBO J (1990) 1.04
Circulating levels of colony-stimulating factor 1 as a prognostic indicator in 82 patients with epithelial ovarian cancer. Br J Cancer (1994) 1.03
Receptors for IgG complexes activate synthesis of monocyte chemoattractant peptide 1 and colony-stimulating factor 1. Proc Natl Acad Sci U S A (1992) 1.00
Phosphatidylcholine hydrolysis and c-myc expression are in collaborating mitogenic pathways activated by colony-stimulating factor 1. Mol Cell Biol (1993) 0.99
The effect of activating mutations on dimerization, tyrosine phosphorylation and internalization of the macrophage colony stimulating factor receptor. Mol Biol Cell (1994) 0.98
Macrophage growth arrest by cyclic AMP defines a distinct checkpoint in the mid-G1 stage of the cell cycle and overrides constitutive c-myc expression. Mol Cell Biol (1992) 0.96
Developmental and functional significance of the CSF-1 proteoglycan chondroitin sulfate chain. Blood (2005) 0.96
Colony-stimulating factor 1-mediated regulation of a chimeric c-fms/v-fms receptor containing the v-fms-encoded tyrosine kinase domain. Proc Natl Acad Sci U S A (1988) 0.91
Transduction of human colony-stimulating factor-1 (CSF-1) receptor into interleukin-3-dependent mouse myeloid cells induces both CSF-1-dependent and factor-independent growth. Mol Cell Biol (1989) 0.87
Antibody-induced mitogenicity mediated by a chimeric CD2-c-fms receptor. Mol Cell Biol (1990) 0.83
Association between phosphatidylinositol-3 kinase, Cbl and other tyrosine phosphorylated proteins in colony-stimulating factor-1-stimulated macrophages. Biochem J (1996) 0.82
Subtilase cytotoxin enhances Escherichia coli survival in macrophages by suppression of nitric oxide production through the inhibition of NF-κB activation. Infect Immun (2012) 0.81
Separation and characterization of the activated pool of colony-stimulating factor 1 receptor forming distinct multimeric complexes with signalling molecules in macrophages. Mol Cell Biol (1999) 0.81
The TAL1/SCL transcription factor regulates cell cycle progression and proliferation in differentiating murine bone marrow monocyte precursors. Mol Cell Biol (2010) 0.81
Chromatin-associated CSF-1R binds to the promoter of proliferation-related genes in breast cancer cells. Oncogene (2013) 0.80
Different pathways of colony-stimulating factor 1 degradation in macrophage populations revealed by wortmannin sensitivity. Biochem J (1998) 0.79
Selective Regulation of MAPK Signaling Mediates RANKL-dependent Osteoclast Differentiation. Int J Biol Sci (2016) 0.78
Loss of both CSF1R (FMS) alleles in patients with myelodysplasia and a chromosome 5 deletion. Proc Natl Acad Sci U S A (1991) 0.76
Diverse in vivo effects of soluble and membrane-bound M-CSF on tumor-associated macrophages in lymphoma xenograft model. Oncotarget (2016) 0.76
CSF-1 receptor signalling is governed by pre-requisite EHD1 mediated receptor display on the macrophage cell surface. Cell Signal (2016) 0.75
Understanding macrophage differentiation during space flight: The importance of ground-based experiments before space flight. Recent Pat Space Technol (2013) 0.75
The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF-1. Cell (1985) 10.17
Survival of mononuclear phagocytes depends on a lineage-specific growth factor that the differentiated cells selectively destroy. Cell (1982) 5.19
Total absence of colony-stimulating factor 1 in the macrophage-deficient osteopetrotic (op/op) mouse. Proc Natl Acad Sci U S A (1990) 5.05
Factors regulating macrophage production and growth. Purification and some properties of the colony stimulating factor from medium conditioned by mouse L cells. J Biol Chem (1977) 4.63
Role of colony stimulating factor-1 in the establishment and regulation of tissue macrophages during postnatal development of the mouse. Development (1994) 3.86
CSF-1--a mononuclear phagocyte lineage-specific hemopoietic growth factor. J Cell Biochem (1983) 3.31
Activation of human macrophages. Comparison of other cytokines with interferon-gamma. J Exp Med (1984) 3.02
The macrophage colony-stimulating factor, CSF-1. Methods Enzymol (1985) 2.91
Role for c-myc in activation-induced apoptotic cell death in T cell hybridomas. Science (1992) 2.90
Anti-colony-stimulating factor-1 antibody staining in primary breast adenocarcinomas correlates with marked inflammatory cell infiltrates and prognosis. J Natl Cancer Inst (1994) 2.58
Macrophage colony-stimulating factor is indispensable for both proliferation and differentiation of osteoclast progenitors. J Clin Invest (1993) 2.52
Isolation and characterization of a cloned growth factor dependent macrophage cell line, BAC1.2F5. J Cell Physiol (1987) 2.42
Colony-stimulating factor (CSF) radioimmunoassay: detection of a CSF subclass stimulating macrophage production. Proc Natl Acad Sci U S A (1979) 2.35
Apparent role of the macrophage growth factor, CSF-1, in placental development. Nature (1988) 2.22
Stimulation of macrophage plasminogen activator activity by colony-stimulating factors. J Cell Physiol (1980) 2.15
Specific interaction of murine colony-stimulating factor with mononuclear phagocytic cells. J Cell Biol (1980) 2.12
The Cbl protooncoprotein stimulates CSF-1 receptor multiubiquitination and endocytosis, and attenuates macrophage proliferation. EMBO J (1999) 2.08
Production of colony-stimulating factors (CSFs) during infection: separate determinations of macrophage-, granulocyte-, granulocyte-macrophage-, and multi-CSFs. Infect Immun (1988) 2.04
Partial replacement of serum by selenite, transferrin, albumin and lecithin in haemopoietic cell cultures. Nature (1976) 2.02
Regulation of colony-stimulating factor 1 during pregnancy. J Exp Med (1986) 2.00
Distribution of cells bearing receptors for a colony-stimulating factor (CSF-1) in murine tissues. J Cell Biol (1981) 1.99
Complete replacement of serum in primary cultures of erythropoietin-dependent red cell precursors (CFU-E) by albumin, transferrin, iron, unsaturated fatty acid, lecithin and cholesterol. Exp Cell Res (1980) 1.98
Regulation of very primitive, multipotent, hemopoietic cells by hemopoietin-1. Cell (1986) 1.89
Macrophages specifically regulate the concentration of their own growth factor in the circulation. Proc Natl Acad Sci U S A (1987) 1.82
Expression of the human c-fms proto-oncogene product (colony-stimulating factor-1 receptor) on peripheral blood mononuclear cells and choriocarcinoma cell lines. J Clin Invest (1986) 1.77
Temporal expression and location of colony-stimulating factor 1 (CSF-1) and its receptor in the female reproductive tract are consistent with CSF-1-regulated placental development. Proc Natl Acad Sci U S A (1989) 1.77
Molecules stimulating early red cell, granulocyte, macrophage, and megakaryocyte precursors in culture: similarity in size, hydrophobicity, and charge. J Cell Physiol Suppl (1982) 1.77
Factors regulating macrophage production and growth: identity of colony-stimulating factor and macrophage growth factor. J Exp Med (1976) 1.69
c-Cbl is transiently tyrosine-phosphorylated, ubiquitinated, and membrane-targeted following CSF-1 stimulation of macrophages. J Biol Chem (1996) 1.69
Colony stimulating factor and the regulation of granulopoiesis and macrophage production. Fed Proc (1975) 1.68
Human colony-stimulating factor (CSF-1) radioimmunoassay: resolution of three subclasses of human colony-stimulating factors. Blood (1981) 1.67
Induction of macrophage production and proliferation by a purified colony stimulating factor. Nature (1978) 1.66
Effects of human recombinant CSF-GM and highly purified CSF-1 on the formation of multinucleated cells with osteoclast characteristics in long-term bone marrow cultures. J Bone Miner Res (1986) 1.64
Structure-function studies of a colony stimulating factor (CSF-1). J Biol Chem (1982) 1.64
Correction by CSF-1 of defects in the osteopetrotic op/op mouse suggests local, developmental, and humoral requirements for this growth factor. Exp Hematol (1991) 1.62
Delayed hematopoietic development in osteopetrotic (op/op) mice. J Exp Med (1993) 1.62
Synergism between hemopoietic growth factors (HGFs) detected by their effects on cells bearing receptors for a lineage specific HGF: assay of hemopoietin-1. J Cell Physiol (1985) 1.61
cDNA cloning and expression of murine macrophage colony-stimulating factor from L929 cells. Proc Natl Acad Sci U S A (1988) 1.60
Methods for the purification, assay, characterization and target cell binding of a colony stimulating factor (CSF-1). J Immunol Methods (1981) 1.60
Pregnancy impairs resistance of C57BL/6 mice to Leishmania major infection and causes decreased antigen-specific IFN-gamma response and increased production of T helper 2 cytokines. J Immunol (1996) 1.60
Partial purification and some properties of the factor in normal and leukaemic human urine stimulating mouse bone marrow colony growth in vitro. Aust J Exp Biol Med Sci (1969) 1.58
Elongation factor-1 alpha is an overexpressed actin binding protein in metastatic rat mammary adenocarcinoma. J Cell Sci (1996) 1.56
The regulation of mononuclear phagocyte entry into S phase by the colony stimulating factor CSF-1. J Cell Physiol (1985) 1.55
Colony stimulating factor-1 (CSF-1) stimulates temperature dependent phosphorylation and activation of the RAF-1 proto-oncogene product. EMBO J (1990) 1.55
The biology of CSF-1 and its receptor. Curr Top Microbiol Immunol (1992) 1.55
Identification and subcellular localization of proteins that are rapidly phosphorylated in tyrosine in response to colony-stimulating factor 1. Proc Natl Acad Sci U S A (1988) 1.51
Specific binding of the mononuclear phagocyte colony-stimulating factor CSF-1 to the product of the v-fms oncogene. Proc Natl Acad Sci U S A (1986) 1.46
Purification of the colony-stimulating factor 1 receptor and demonstration of its tyrosine kinase activity. Proc Natl Acad Sci U S A (1987) 1.45
A pregnancy defect in the osteopetrotic (op/op) mouse demonstrates the requirement for CSF-1 in female fertility. Dev Biol (1991) 1.42
Inducible production of human macrophage growth factor, CSF-1. Blood (1986) 1.40
Composition and functional integrity of the in vitro hemopoietic microenvironment in acute myelogenous leukemia: effect of macrophage colony-stimulating factor. Exp Hematol (1992) 1.40
Role of dimerization and modification of the CSF-1 receptor in its activation and internalization during the CSF-1 response. EMBO J (1991) 1.38
Protein tyrosine phosphatase-1C is rapidly phosphorylated in tyrosine in macrophages in response to colony stimulating factor-1. J Biol Chem (1992) 1.37
The role of colony-stimulating factor 1 and its receptor in the etiopathogenesis of endometrial adenocarcinoma. Clin Cancer Res (1995) 1.35
Properties of the colony stimulating factor in leukaemic and normal mouse serum. Aust J Exp Biol Med Sci (1968) 1.34
Cytotoxicity of tumour necrosis factor-alpha and gamma-interferon against primary human placental trophoblasts. Placenta (1994) 1.34
Factors from mouse tissues stimulating colony growth of mouse bone marrow cells in vitro. Aust J Exp Biol Med Sci (1971) 1.32
Development of methods for the quantitative in vitro analysis of androgen-dependent and autonomous Shionogi carcinoma 115 cells. Cell (1977) 1.31
Tissue sources of bone marrow colony stimulating factor. J Cell Physiol (1971) 1.30
Cytoadherence of Plasmodium falciparum to intercellular adhesion molecule 1 and chondroitin-4-sulfate expressed by the syncytiotrophoblast in the human placenta. Infect Immun (1997) 1.28
Properties of the mouse embryo conditioned medium factor(s) stimulationg colony formation by mouse bone marrow cells grown in vitro. J Cell Physiol (1971) 1.26
Purification of hemopoietin 1: a multilineage hemopoietic growth factor. Proc Natl Acad Sci U S A (1985) 1.25
Stimulation of bone marrow colony growth in vitro by human urine. Blood (1969) 1.23
Absence of colony-stimulating factor-1 in osteopetrotic (csfmop/csfmop) mice results in male fertility defects. Biol Reprod (1996) 1.20
Stimulation and inhibition by normal human serum of colony formation in vitro by bone marrow cells. Br J Haematol (1971) 1.20
Interleukin 1 plus interleukin 3 plus colony-stimulating factor 1 are essential for clonal proliferation of primitive myeloid bone marrow cells. Exp Hematol (1989) 1.19
FMS (CSF-1 receptor) and CSF-1 transcripts and protein are expressed by human breast carcinomas in vivo and in vitro. Oncogene (1991) 1.18
Quantitative studies on the stimulation of mouse bone marrow colony growth in vitro by normal human urine. Aust J Exp Biol Med Sci (1969) 1.17
Colony-stimulating factor-1 induces rapid behavioural responses in the mouse macrophage cell line, BAC1.2F5. J Cell Sci (1989) 1.16
ICAM-1-mediated adhesion of peripheral blood monocytes to the maternal surface of placental syncytiotrophoblasts: implications for placental villitis. Am J Pathol (1997) 1.16
Standardized bioassay for bone marrow colony stimulating factor in human urine: levels in normal man. J Lab Clin Med (1972) 1.16
Discrimination of a colony stimulating factor subclass by a specific receptor on a macrophage cell line. J Cell Physiol (1980) 1.16
Action of the colony-stimulating factor, CSF-1. Ciba Found Symp (1986) 1.15
Regulation of mouse podocyte process dynamics by protein tyrosine phosphatases rapid communication. Kidney Int (2000) 1.15
Permissive cytomegalovirus infection of primary villous term and first trimester trophoblasts. J Virol (1998) 1.13
Macrophage production during murine listeriosis: colony-stimulating factor 1 (CSF-1) and CSF-1-binding cells in genetically resistant and susceptible mice. Infect Immun (1988) 1.12
Colony-stimulating factor-1 stimulates the formation of multimeric cytosolic complexes of signaling proteins and cytoskeletal components in macrophages. J Biol Chem (1998) 1.11
Chemical crosslinking of the mononuclear phagocyte specific growth factor CSF-1 to its receptor at the cell surface. Biochem Biophys Res Commun (1984) 1.11
Expression of colony-stimulating factor-1 in the human uterus and placenta. J Clin Endocrinol Metab (1992) 1.10
v-raf confers CSF-1 independent growth to a macrophage cell line and leads to immediate early gene expression without MAP-kinase activation. Oncogene (1993) 1.10
Protein tyrosine phosphatase phi regulates paxillin tyrosine phosphorylation and mediates colony-stimulating factor 1-induced morphological changes in macrophages. Mol Cell Biol (2001) 1.09
Enzyme treatment of colony stimulating factor: evidence for a peptide component. Aust J Exp Biol Med Sci (1971) 1.09
The role of cytokines in gestation. Crit Rev Immunol (1994) 1.09
Biology of the hemopoietic microenvironment. Eur J Haematol (1992) 1.08
A novel macrophage actin-associated protein (MAYP) is tyrosine-phosphorylated following colony stimulating factor-1 stimulation. J Biol Chem (1998) 1.08
Haematological effects in mice of partially purified colony stimulating factor (CSF) prepared from human urine. Br J Haematol (1971) 1.07
SHP-1 regulation of p62(DOK) tyrosine phosphorylation in macrophages. J Biol Chem (1999) 1.06
Immunomodulating activity of CVT-E002, a proprietary extract from North American ginseng (Panax quinquefolium). J Pharm Pharmacol (2001) 1.05
Regulation of monocyte chemoattractant protein-1 and macrophage colony-stimulating factor-1 by IFN-gamma, tumor necrosis factor-alpha, IgG aggregates, and cAMP in mouse mesangial cells. J Immunol (1993) 1.04
Circulating levels of CSF-1 (M-CSF) a lymphohematopoietic cytokine may be a useful marker of disease status in patients with malignant ovarian neoplasms. Int J Radiat Oncol Biol Phys (1989) 1.04
CSF-1 stimulated multiubiquitination of the CSF-1 receptor and of Cbl follows their tyrosine phosphorylation and association with other signaling proteins. J Cell Biochem (1999) 1.04