Published in Proc Natl Acad Sci U S A on October 15, 1992
Commitment and differentiation of osteoclast precursor cells by the sequential expression of c-Fms and receptor activator of nuclear factor kappaB (RANK) receptors. J Exp Med (1999) 3.07
Vascular endothelial growth factor can substitute for macrophage colony-stimulating factor in the support of osteoclastic bone resorption. J Exp Med (1999) 2.13
BCA-1 is highly expressed in Helicobacter pylori-induced mucosa-associated lymphoid tissue and gastric lymphoma. J Clin Invest (1999) 1.94
Macrophage colony-stimulating factor stimulates survival and chemotactic behavior in isolated osteoclasts. J Exp Med (1993) 1.63
Colony-stimulating factor-1 induces cytoskeletal reorganization and c-src-dependent tyrosine phosphorylation of selected cellular proteins in rodent osteoclasts. J Clin Invest (1997) 1.32
Mechanisms of bone metastases of breast cancer. Endocr Relat Cancer (2009) 1.25
Colony-stimulating factor-1 (CSF-1) directly inhibits receptor activator of nuclear factor-{kappa}B ligand (RANKL) expression by osteoblasts. Endocrinology (2009) 0.87
ERK1 regulates the hematopoietic stem cell niches. PLoS One (2012) 0.82
Molecular cloning and expression of a unique rabbit osteoclastic phosphotyrosyl phosphatase. Biochem J (1996) 0.80
The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF-1. Cell (1985) 10.17
The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene. Nature (1990) 8.94
Survival of mononuclear phagocytes depends on a lineage-specific growth factor that the differentiated cells selectively destroy. Cell (1982) 5.19
Total absence of colony-stimulating factor 1 in the macrophage-deficient osteopetrotic (op/op) mouse. Proc Natl Acad Sci U S A (1990) 5.05
CSF-1--a mononuclear phagocyte lineage-specific hemopoietic growth factor. J Cell Biochem (1983) 3.31
Hematological characterization of congenital osteopetrosis in op/op mouse. Possible mechanism for abnormal macrophage differentiation. J Exp Med (1982) 2.39
Congenital osteoclast deficiency in osteopetrotic (op/op) mice is cured by injections of macrophage colony-stimulating factor. J Exp Med (1991) 2.31
Osteopetrosis, a new recessive skeletal mutation on chromosome 12 of the mouse. J Hered (1976) 2.08
Macrophage colony stimulating factor restores in vivo bone resorption in the op/op osteopetrotic mouse. Endocrinology (1990) 2.02
Impairment of macrophage colony-stimulating factor production and lack of resident bone marrow macrophages in the osteopetrotic op/op mouse. J Bone Miner Res (1990) 1.97
Immunophenotypic differences between osteoclasts and macrophage polykaryons: immunohistological distinction and implications for osteoclast ontogeny and function. J Clin Pathol (1990) 1.94
The interaction of 125I-colony-stimulating factor-1 with bone marrow-derived macrophages. J Biol Chem (1986) 1.92
Deficiency of osteoclasts in osteopetrotic mice is due to a defect in the local microenvironment provided by osteoblastic cells. Endocrinology (1991) 1.90
Macrophages specifically regulate the concentration of their own growth factor in the circulation. Proc Natl Acad Sci U S A (1987) 1.82
Investigation of cell lineage in bone using a chimaera of chick and quial embryonic tissue. Nature (1975) 1.80
Murine c-fms cDNA: cloning, sequence analysis and retroviral expression. Oncogene Res (1988) 1.79
In vitro osteoclast generation from different bone marrow fractions, including a highly enriched haematopoietic stem cell population. Nature (1986) 1.50
Calcitonin receptors as markers for osteoclastic differentiation: correlation between generation of bone-resorptive cells and cells that express calcitonin receptors in mouse bone marrow cultures. Endocrinology (1989) 1.44
Expression of the c-fms proto-oncogene and of the cytokine, CSF-1, during mouse embryogenesis. Dev Biol (1989) 1.42
Role of colony-stimulating factors in osteoclast development. J Bone Miner Res (1991) 1.16
Growth of osteoclast precursor-like cells from whole mouse bone marrow: inhibitory effect of CSF-1. Bone Miner (1987) 1.14
Human macrophage colony-stimulating factor inhibits bone resorption by osteoclasts disaggregated from rat bone. J Cell Physiol (1988) 1.13
The mononuclear phagocyte system of the mouse defined by immunohistochemical localization of antigen F4/80: macrophages of bone and associated connective tissue. J Cell Sci (1984) 1.13
Osteotropic factor responsiveness of highly purified populations of early and late precursors for human multinucleated cells expressing the osteoclast phenotype. J Bone Miner Res (1991) 1.04
The effect of parathyroid hormone, 1,25-dihydroxycholecalciferol and prostaglandins on the cytoplasmic activity of isolated osteoclasts. J Pathol (1982) 1.03
Differentiation kinetics of osteoclasts in the periosteum of embryonic bones in vivo and in vitro. Anat Rec (1986) 1.03
Lineage specific receptors used to identify a growth factor for developmentally early hemopoietic cells: assay of hemopoietin-2. J Cell Physiol (1985) 1.00
Effects of ionizing irradiation on formation and resorbing activity of osteoclasts in vitro. Lab Invest (1985) 0.97
Identification of osteoclast precursors in multilineage hemopoietic colonies. Endocrinology (1991) 0.95
Localization and function of tissue macrophages. Ciba Found Symp (1986) 0.94
Effect of macrophage colony-stimulating factor on in vitro osteoclast generation and bone resorption. Endocrinology (1992) 0.91
Lack of Fc receptors on osteoclasts. Cell Tissue Res (1980) 0.86
Specificity of action of colony-stimulating factors in the differentiation of granulocytes and macrophages. Ciba Found Symp (1986) 0.81
c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling. Science (1994) 5.97
Hyperthermia in combined treatment of cancer. Lancet Oncol (2002) 4.41
Role of colony stimulating factor-1 in the establishment and regulation of tissue macrophages during postnatal development of the mouse. Development (1994) 3.86
GATA-4/5/6, a subfamily of three transcription factors transcribed in developing heart and gut. J Biol Chem (1994) 3.65
Patient-related barriers to management of cancer pain. Pain (1993) 3.33
The mouse stargazer gene encodes a neuronal Ca2+-channel gamma subunit. Nat Genet (1998) 3.31
Microinjection of early SV40 DNA fragments and T antigen. Methods Enzymol (1980) 3.01
Current use of bisphosphonates in oncology. International Bone and Cancer Study Group. J Clin Oncol (1998) 2.73
24-hour coverage by attending physicians: a new paradigm. AJR Am J Roentgenol (1996) 2.70
Primary interferon resistance and treatment response in chronic hepatitis C infection: a pilot study. Lancet (2001) 2.40
Anomalous origin of the right vertebral artery: review of the literature and case report of right vertebral artery origin distal to the left subclavian artery. AJNR Am J Neuroradiol (1999) 2.34
Diphosphonates inhibit hydroxyapatite dissolution in vitro and bone resorption in tissue culture and in vivo. Science (1969) 2.30
Early events in T-cell maturation. Annu Rev Immunol (1987) 2.27
Diphosphonates inhibit formation of calcium phosphate crystals in vitro and pathological calcification in vivo. Science (1969) 2.20
Characterization and cloning of the E11 antigen, a marker expressed by rat osteoblasts and osteocytes. Bone (1996) 2.11
Intraaneurysmal flow: evaluation with Doppler guidewires. AJNR Am J Neuroradiol (1996) 2.09
Mapping of early SV40-specific functions by microinjection of different early viral DNA fragments. Cell (1978) 2.08
Expression of interleukin-8 gene in inflammatory bowel disease is related to the histological grade of active inflammation. Am J Pathol (1994) 2.04
Macrophage colony stimulating factor restores in vivo bone resorption in the op/op osteopetrotic mouse. Endocrinology (1990) 2.02
Impairment of macrophage colony-stimulating factor production and lack of resident bone marrow macrophages in the osteopetrotic op/op mouse. J Bone Miner Res (1990) 1.97
Magnetic resonance cholangiopancreatography-guided unilateral endoscopic stent placement for Klatskin tumors. Gastrointest Endosc (2001) 1.90
Use of dermestid beetles for cleaning bones. Calcif Tissue Int (1980) 1.88
Inductive heating of ferrimagnetic particles and magnetic fluids: physical evaluation of their potential for hyperthermia. 1993. Int J Hyperthermia (2009) 1.87
Liver tumors: comparison of MR imaging with Gd-EOB-DTPA and Gd-DTPA. Radiology (1996) 1.86
Effect of ethane-1-hydroxy-1,1-diphosphonate (EHDP) and dichloromethylene diphosphonate (Cl 2 MDP) on the calcification and resorption of cartilage and bone in the tibial epiphysis and metaphysis of rats. Calcif Tissue Res (1973) 1.85
Analysis of naturally occurring delayed-type hypersensitivity reactions in leprosy by in situ hybridization. J Exp Med (1989) 1.82
Drug smuggling by ingested cocaine-filled packages: conventional x-ray and ultrasound. Abdom Imaging (1995) 1.79
Inorganic pyrophosphate in plasma, urine, and synovial fluid of patients with pyrophosphate arthropathy (chondrocalcinosis or pseudogout). Lancet (1970) 1.77
The binding of pyrophosphate and two diphosphonates by hydroxyapatite crystals. Calcif Tissue Res (1973) 1.77
Inductive heating of ferrimagnetic particles and magnetic fluids: physical evaluation of their potential for hyperthermia. Int J Hyperthermia (1993) 1.77
Effect of pyrophosphate on hydroxyapatite and its implications in calcium homeostasis. Nature (1966) 1.68
Effects of magnetic fluid hyperthermia (MFH) on C3H mammary carcinoma in vivo. Int J Hyperthermia (1998) 1.67
Cellular uptake of magnetic fluid particles and their effects on human adenocarcinoma cells exposed to AC magnetic fields in vitro. Int J Hyperthermia (1997) 1.66
T1 alpha protein is developmentally regulated and expressed by alveolar type I cells, choroid plexus, and ciliary epithelia of adult rats. Am J Respir Cell Mol Biol (1996) 1.64
Pyrophosphate and diphosphonates in calcium metabolism and their possible role in renal failure. Arch Intern Med (1969) 1.64
Cytochrome P450RAI(CYP26) promoter: a distinct composite retinoic acid response element underlies the complex regulation of retinoic acid metabolism. Mol Endocrinol (2000) 1.62
Hepatocellular carcinoma in association with hepatic focal nodular hyperplasia. Acta Radiol (2006) 1.59
Bisphosphonates act on rat bone resorption through the mediation of osteoblasts. J Clin Invest (1993) 1.58
Inorganic pyrophosphate in plasma in normal persons and in patients with hypophosphatasia, osteogenesis imperfecta, and other disorders of bone. J Clin Invest (1971) 1.55
Differential in situ expression of the genes encoding the chemokines MCP-1 and RANTES in human inflammatory bowel disease. J Pathol (1996) 1.52
Hepatocellular carcinoma: evaluation with dynamic and static gadobenate dimeglumine-enhanced MR imaging and histopathologic correlation. Radiology (1997) 1.52
Comparison of CT, MRI and FDG-PET in response prediction of patients with locally advanced rectal cancer after multimodal preoperative therapy: is there a benefit in using functional imaging? Eur Radiol (2005) 1.49
Initially unresectable hilar cholangiocarcinoma: hepatic regeneration after transarterial embolization. Radiology (1998) 1.49
Transarterial chemoembolization for hepatocellular carcinoma: volumetric and morphologic CT criteria for assessment of prognosis and therapeutic success-results from a liver transplantation center. Radiology (2000) 1.48
Electron-beam computed tomography in the assessment of coronary artery disease after heart transplantation. Circulation (2000) 1.47
Kinetic and molecular properties of the dihydrofolate reductase from pyrimethamine-sensitive and pyrimethamine-resistant clones of the human malaria parasite Plasmodium falciparum. Mol Pharmacol (1987) 1.46
Magnetic resonance imaging including magnetic resonance cholangiopancreatography for tumor localization and therapy planning in malignant hilar obstructions. Acta Radiol (2005) 1.46
Nonlymphocyte-derived tumor necrosis factor is required for induction of colitis in recombination activating gene (RAG)2(-/-) mice upon transfer of CD4(+)CD45RB(hi) T cells. J Exp Med (1999) 1.46
Distribution and patterns of blunt traumatic cervical spine injury. Ann Emerg Med (2001) 1.43
Inhibition by pyrophosphate and polyphosphate of aortic calcification induced by vitamin D3 in rats. Clin Sci (1968) 1.43
Localization of a gene (MCUL1) for multiple cutaneous leiomyomata and uterine fibroids to chromosome 1q42.3-q43. Am J Hum Genet (2001) 1.42
Simulation studies promote technological development of radiofrequency phased array hyperthermia. 1996. Int J Hyperthermia (2009) 1.41
[Use of high resolution color Doppler sonography in diagnosis of temporal arteritis]. Rofo (1998) 1.41
Design and test of a new multi-amplifier system with phase and amplitude control. Int J Hyperthermia (1998) 1.41
[Indirect MR arthrography in the diagnosis of rotator cuff lesions]. Rofo (2000) 1.39
Localized expression of mRNA for phagocyte-specific chemotactic cytokines in human periodontal infections. Infect Immun (1994) 1.39
Inhibitors and promoters of stone formation. Kidney Int (1978) 1.38
Uveal melanoma: detection of extraocular growth with MR imaging and US. Radiology (1997) 1.38
[Project graph technique for time management in abdominal ultrasound evaluations]. Ultraschall Med (1999) 1.38
[The value of radioimmunoscintigraphy compared to computed tomography in the diagnosis and relapse diagnosis of colorectal tumors]. Rofo (1992) 1.38
Behavioral sensitization to cocaine is associated with increased glutamate receptor trafficking to the postsynaptic density after extended withdrawal period. Neuroscience (2008) 1.36
Expression of perforin and granzymes in vivo: potential diagnostic markers for activated cytotoxic cells. Immunol Today (1991) 1.36
In vitro coronary artery imaging with sixteen-slice helical computed tomography. Acta Radiol (2004) 1.36
The influence of pyrophosphate, condensed phosphates, phosphonates and other phosphate compounds on the dissolution of hydroxyapatite in vitro and on bone resorption induced by parathyroid hormone in tissue culture and in thyroparathyroidectomised rats. Calcif Tissue Res (1970) 1.35
Expression of tissue transglutaminase in skeletal tissues correlates with events of terminal differentiation of chondrocytes. J Cell Biol (1993) 1.35
Effect of bisphosphonates on proliferation and viability of mouse bone marrow-derived macrophages. J Bone Miner Res (1987) 1.35
Public attitudes about genetic testing for Alzheimer's disease. Health Aff (Millwood) (2001) 1.34
Structure-activity relationships of various bisphosphonates. Calcif Tissue Int (1983) 1.31
Regulatory function of simian virus 40 DNA replication for late viral gene expression. Proc Natl Acad Sci U S A (1977) 1.31
Regulation and function of the CXC chemokine ENA-78 in monocytes and its role in disease. J Leukoc Biol (1997) 1.31
The C-X-C chemokine ENA-78 is preferentially expressed in intestinal epithelium in inflammatory bowel disease. Gastroenterology (1997) 1.30
Inorganic phosphate homeostasis. Renal adaptation to the dietary intake in intact and thyroparathyroidectomized rats. J Clin Invest (1976) 1.29
Genes encoding tumor necrosis factor alpha and granzyme A are expressed during development of autoimmune diabetes. Proc Natl Acad Sci U S A (1990) 1.28
Regulatory mechanism of simian virus 40 gene expression in permissive and in nonpermissive cells. J Virol (1976) 1.28
Cytotoxic cells are activated in cellular infiltrates of alcoholic chronic pancreatitis. Gastroenterology (1997) 1.26
The effects of diphosphonates on the growth and glycolysis of connective-tissue cells in culture. Biochem J (1978) 1.26
Exposure of casino employees to environmental tobacco smoke. J Occup Environ Med (1998) 1.25
Brain tumors: MR imaging with gadolinium-DTPA. Radiology (1985) 1.24
Bisphosphonates induce osteoblasts to secrete an inhibitor of osteoclast-mediated resorption. Endocrinology (1996) 1.24
BM 21.0955, a potent new bisphosphonate to inhibit bone resorption. J Bone Miner Res (1991) 1.23
Dural sinus thrombosis: value of venous MR angiography for diagnosis and follow-up. AJR Am J Roentgenol (1994) 1.22
Infertility associated with incomplete spermatogenic arrest and oligozoospermia in Egr4-deficient mice. Development (1999) 1.22
Letter: Skin reactions to practolol. Br Med J (1974) 1.21
Disruption of an inner arm dynein heavy chain gene results in asthenozoospermia and reduced ciliary beat frequency. Hum Mol Genet (2001) 1.19
Activated CD4+ and CD8+ cytotoxic cells are present in increased numbers in the intestinal mucosa from patients with active inflammatory bowel disease. Am J Pathol (1998) 1.18
Can bisphosphonates be given to patients with fractures? J Bone Miner Res (2001) 1.18
A new method for the measurement of itch and the response to treatment. Br J Dermatol (1975) 1.17
Biochemical and biophysical evidence for gamma 2 subunit association with neuronal voltage-activated Ca2+ channels. J Biol Chem (2001) 1.16
Methicillin-resistant Staphylococcus aureus whole-body decolonization among hospitalized patients with variable site colonization by using mupirocin in combination with octenidine dihydrochloride. J Hosp Infect (2003) 1.16
Ion transport in sperm signaling. Dev Biol (2001) 1.16
Regulation of SV40 gene expression. Adv Cancer Res (1981) 1.15
Diphosphonates in the treatment of myositis ossificans. Lancet (1969) 1.14
Impact of overall treatment time on local control of anal cancer treated with radiochemotherapy. Oncology (2003) 1.14
Extracellular interaction of the voltage-dependent Ca2+ channel alpha2delta and alpha1 subunits. J Biol Chem (1997) 1.14