Published in Proc Natl Acad Sci U S A on May 01, 1978
Isolation and characterization of a major tandem repeat family from the human X chromosome. Nucleic Acids Res (1983) 2.94
Chromosome-specific organization of human alpha satellite DNA. Am J Hum Genet (1985) 2.10
Chromosomal basis of X chromosome inactivation: identification of a multigene domain in Xp11.21-p11.22 that escapes X inactivation. Proc Natl Acad Sci U S A (1998) 1.43
Partial purification and characterization of DNA from the human X chromosome. Proc Natl Acad Sci U S A (1979) 1.01
Contiguous deletion of the X-linked adrenoleukodystrophy gene (ABCD1) and DXS1357E: a novel neonatal phenotype similar to peroxisomal biogenesis disorders. Am J Hum Genet (2002) 1.00
Histone modifications within the human X centromere region. PLoS One (2009) 0.97
Carcinoembryonic antigen family: expression in a mouse L-cell transfectant and characterization of a partial cDNA in bacteriophage lambda gt11. Proc Natl Acad Sci U S A (1987) 0.96
Human transferrin receptor: expression of the receptor is assigned to chromosome 3. Proc Natl Acad Sci U S A (1982) 0.94
Genetic and biochemical characterization of human lymphocyte cell surface antigens. The A-1A5 and A-3A4 determinants. J Exp Med (1984) 0.93
SELECTION OF HYBRIDS FROM MATINGS OF FIBROBLASTS IN VITRO AND THEIR PRESUMED RECOMBINANTS. Science (1964) 24.40
Clonal growth of mammalian cells in vitro; growth characteristics of colonies from single HeLa cells with and without a feeder layer. J Exp Med (1956) 22.68
THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS. Exp Cell Res (1965) 21.61
Identification of human chromosomes by DNA-binding fluorescent agents. Chromosoma (1970) 6.57
The status of the gene map of the human chromosomes. Science (1977) 5.44
THREE DEGREES OF GUANYLIC ACID--INOSINIC ACID PYROPHOSPHORYLASE DEFICIENCY IN MOUSE FIBROBLASTS. Nature (1964) 4.67
Localization of the human alpha-globin structural gene to chromosome 16 in somatic cell hybrids by molecular hybridization assay. Cell (1977) 4.34
Transfer of the human gene for hypoxanthine-guanine phosphoribosyltransferase via isolated human metaphase chromosomes into mouse L-cells. Proc Natl Acad Sci U S A (1975) 3.91
A review of enzyme polymorphism, linkage and electrophoretic conditions for mouse and somatic cell hybrids in starch gels. J Histochem Cytochem (1973) 3.33
THE INOSINIC ACID PYROPHOSPHORYLASE ACTIVITY OF MOUSE FIBROBLASTS PARTIALLY RESISTANT TO 8-AZAGUANINE. Proc Natl Acad Sci U S A (1963) 2.75
A sequential staining technique for the chromosomal analysis of the interspecific mouse/hamster and mouse/human somatic cell hybrids. Exp Cell Res (1977) 2.71
STUDIES ON THYMIDINE KINASE IN CULTURED MOUSE FIBROBLASTS. Biochim Biophys Acta (1965) 2.47
The beta2-microglobulin gene is on chromosome 15 and not in the HL-A region. Nature (1975) 2.29
Fluorescence-activated cell sorting. Sci Am (1976) 2.12
Genetics of somatic mammalian cells: lethal antigens as genetic markers for study of human linkage groups. Proc Natl Acad Sci U S A (1971) 2.00
Differential staining of interspecific chromosomes in somatic cell hybrids by alkaline Giemsa stain. Somatic Cell Genet (1976) 1.98
Assignment of the gene for adenine phosphoribosyltransferase to human chromosome 16 by mouse-human somatic cell hybridization. Proc Natl Acad Sci U S A (1974) 1.97
Human chromosome 21 dosage: effect on the expression of the interferon induced antiviral state. Science (1974) 1.95
Quantitative single cell analysis and sorting. Science (1977) 1.82
Two-color immunofluorescence using a fluorescence-activated cell sorter. J Histochem Cytochem (1977) 1.67
Antibodies to a cell-surface component coded by human chromosome 21 inhibit action of interferon. Nature (1976) 1.35
Human antigen and enzyme markers in man-Chinese hamster somatic cell hybrids: evidence for synteny between the HL-A, PGM3, ME1, and IPO-B loci. Proc Natl Acad Sci U S A (1974) 1.32
Genetic analysis of the cell surface: association of human chromosome 5 with sensitivity to diphtheria toxin in mouse-human somatic cell hybrids. Proc Natl Acad Sci U S A (1975) 1.26
Selective and nonselective isolation of temperature-sensitive mutants of mouse L-cells and their characterization. J Cell Physiol (1971) 1.25
Complement-mediated antiserum cytotoxic reactions to human chromosome 7 coded antigen(s): immunoselection of rearranged human chromosome 7 in human-mouse somatic cell hybrids. J Exp Med (1977) 1.15
Detection of interspecific translocations in mouse-human hybrids by alkaline Giemsa staining. Exp Cell Res (1976) 1.15
Mammalian chromosome identification in interspecific hybride cells using "Hoechst 33258". Humangenetik (1975) 1.14
beta2-microglobulin locus on human chromosome 15. Somatic Cell Genet (1976) 1.12
Chromosomal localization of human genes governing the interferon-induced antiviral state. Proc Natl Acad Sci U S A (1975) 1.09
Somatic cell hybrids between mouse peritoneal macrophages and SV40-transformed human cells. III. Identification of surface antigens coded for by human chromosomes 7 and 17. J Immunol (1977) 0.88
Expression of the Xga antigen on cells in culture and its segregation in somatic cell hybrids. Ann Hum Genet (1974) 0.87
A (6;21) translocation, unbalanced, 46 chromosomes. Repository identification no. GM-144. Cytogenet Cell Genet (1974) 0.86
Linkage relationships of the HL-A system and beta 2 microglobulin. Birth Defects Orig Artic Ser (1975) 0.78
A human chromosomal determinant for susceptibility to herpes simplex virus. Nature (1976) 0.78
Evidence for synteny between a polio receptor gene and glucose phosphate isomerase (GPI) by analysis of human-mouse hybrids. Cytogenet Cell Genet (1976) 0.78
Regional mapping of the X-linked gene for a human cell surface antigen, SA-X. Birth Defects Orig Artic Ser (1976) 0.77
A (1;15) translocation, balanced, 46 chromosomes. Repository identification No. GM-126. Cytogenet Cell Genet (1975) 0.77
Initial sequencing and analysis of the human genome. Nature (2001) 212.86
The DNA sequence of human chromosome 22. Nature (1999) 30.88
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature (1998) 21.49
A physical map of the human genome. Nature (2001) 12.39
The DNA sequence of human chromosome 21. Nature (2000) 10.66
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase. Nat Genet (2000) 7.83
Genetic transformation of mouse embryos by microinjection of purified DNA. Proc Natl Acad Sci U S A (1980) 5.47
Positional cloning of the APECED gene. Nat Genet (1997) 5.47
The status of the gene map of the human chromosomes. Science (1977) 5.44
Mechanisms of DNA uptake by mammalian cells: fate of exogenously added DNA monitored by the use of fluorescent dyes. Proc Natl Acad Sci U S A (1982) 5.30
trans activation of the latent Epstein-Barr virus (EBV) genome after transfection of the EBV DNA fragment. J Virol (1986) 5.25
Somatic cell genetics and gene families. Science (1983) 4.61
Complete nucleotide sequence of an infectious clone of human T-cell leukemia virus type II: an open reading frame for the protease gene. Proc Natl Acad Sci U S A (1985) 4.28
A conversational system for the computer analysis of nucleic acid sequences. Nucleic Acids Res (1981) 4.07
Transfer of the human gene for hypoxanthine-guanine phosphoribosyltransferase via isolated human metaphase chromosomes into mouse L-cells. Proc Natl Acad Sci U S A (1975) 3.91
Use of a protein-blotting procedure and a specific DNA probe to identify nuclear proteins that recognize the promoter region of the transferrin receptor gene. Proc Natl Acad Sci U S A (1985) 3.91
Mechanisms and applications of DNA-mediated gene transfer in mammalian cells - a review. Gene (1981) 3.46
Gene transfer, expression, and molecular cloning of the human transferrin receptor gene. Cell (1984) 3.42
A review of enzyme polymorphism, linkage and electrophoretic conditions for mouse and somatic cell hybrids in starch gels. J Histochem Cytochem (1973) 3.33
Human nucleolus organizers on nonhomologous chromosomes can share the same ribosomal gene variants. Proc Natl Acad Sci U S A (1981) 3.21
The human transferrin receptor gene: genomic organization, and the complete primary structure of the receptor deduced from a cDNA sequence. Cell (1984) 3.14
Identification of the spinocerebellar ataxia type 2 gene using a direct identification of repeat expansion and cloning technique, DIRECT. Nat Genet (1996) 3.07
Host range mutant of human immunodeficiency virus type 1: modification of cell tropism by a single point mutation at the neutralization epitope in the env gene. J Virol (1991) 3.07
Molecular cloning and chromosome mapping of a mouse DNA sequence homologous to homeotic genes of Drosophila. Cell (1984) 2.89
Controlled production of proliferating somatic cell hybrids. J Cell Biol (1970) 2.78
Mammalian Trithorax and polycomb-group homologues are antagonistic regulators of homeotic development. Proc Natl Acad Sci U S A (1999) 2.76
A sequential staining technique for the chromosomal analysis of the interspecific mouse/hamster and mouse/human somatic cell hybrids. Exp Cell Res (1977) 2.71
Chromosomal localization of human beta globin gene on human chromosome 11 in somatic cell hybrids. Proc Natl Acad Sci U S A (1978) 2.65
International system for human gene nomenclature (1979) ISGN (1979). Cytogenet Cell Genet (1979) 2.58
Regional mapping of the phenylalanine hydroxylase gene and the phenylketonuria locus in the human genome. Proc Natl Acad Sci U S A (1985) 2.58
The linkage of genes for the human interferon-induced antiviral protein and indophenol oxidase-B traits to chromosome G-21. J Exp Med (1973) 2.57
Pulmonary function, postoperative pain, and serum cytokine level after lobectomy: a comparison of VATS and conventional procedure. Ann Thorac Surg (2001) 2.55
A SNP resource for human chromosome 22: extracting dense clusters of SNPs from the genomic sequence. Genome Res (2001) 2.49
Linkage analysis in man by somatic cell genetics. Nature (1973) 2.33
Integration and stable germ line transmission of genes injected into mouse pronuclei. Science (1981) 2.31
Characterization of autoantibodies in pemphigus using antigen-specific enzyme-linked immunosorbent assays with baculovirus-expressed recombinant desmogleins. J Immunol (1997) 2.31
Localization of multidrug resistance-associated DNA sequences to human chromosome 7. Somat Cell Mol Genet (1986) 2.27
Gene transfer into mouse embryos: production of transgenic mice by pronuclear injection. Methods Enzymol (1983) 2.23
Two steps in the evolution of Antennapedia-class vertebrate homeobox genes. Proc Natl Acad Sci U S A (1989) 2.23
Cloning and chromosomal mapping of the human nonfunctional gene for L-gulono-gamma-lactone oxidase, the enzyme for L-ascorbic acid biosynthesis missing in man. J Biol Chem (1994) 2.22
Spatial restriction in expression of a mouse homoeo box locus within the central nervous system. Nature (1986) 2.16
Molecular cloning and structural analysis of murine thymidine kinase genomic and cDNA sequences. Mol Cell Biol (1985) 2.13
Gene linkage analysis in the mouse by somatic cell hybridization: assignment of adenine phosphoribosyltransferase to chromosome 8 and alpha-galactosidase to the X chromosome. Somatic Cell Genet (1975) 2.11
Chromosomal location of structural genes encoding murine immunoglobulin lambda light chains. Genetics of murine lambda light chains. J Exp Med (1981) 2.07
Charcot-Marie-Tooth neuropathy type 1B is associated with mutations of the myelin P0 gene. Nat Genet (1993) 2.07
Insertion of beta-satellite repeats identifies a transmembrane protease causing both congenital and childhood onset autosomal recessive deafness. Nat Genet (2001) 2.06
DNA-mediated gene transfer of a circular plasmid into murine cells. Proc Natl Acad Sci U S A (1979) 2.02
Thoracoscopic operation for secondary pneumothorax under local and epidural anesthesia in high-risk patients. Ann Thorac Surg (1998) 1.99
Differential staining of interspecific chromosomes in somatic cell hybrids by alkaline Giemsa stain. Somatic Cell Genet (1976) 1.98
Microcell-mediated transfer of murine chromosomes into mouse, Chinese hamster, and human somatic cells. Proc Natl Acad Sci U S A (1977) 1.97
Assignment of the gene for adenine phosphoribosyltransferase to human chromosome 16 by mouse-human somatic cell hybridization. Proc Natl Acad Sci U S A (1974) 1.97
Glutamate oxalate transaminase (GOT) genetics in Mus musculus: linkage, polymorphism, and phenotypes of the Got-2 and Got-1 loci. Biochem Genet (1970) 1.96
A new era in mammalian gene mapping: somatic cell genetics and recombinant DNA methodologies. Nature (1981) 1.96
Human chromosome 21 dosage: effect on the expression of the interferon induced antiviral state. Science (1974) 1.95
Assignment of three human genes to chromosomes (LDH-A to 11, TK to 17, and IDH to 20) and evidence for translocation between human and mouse chromosomes in somatic cell hybrids (thymidine kinase-lactate dehydrogenase A-isocitrate dehydrogenase-C-11, E-17, and F-20 chromosomes). Proc Natl Acad Sci U S A (1972) 1.93
Homeo box gene complex on mouse chromosome 11: molecular cloning, expression in embryogenesis, and homology to a human homeo box locus. Cell (1985) 1.92
Manipulation of the small intestine as a cause of the increased inflammatory response after open compared with laparoscopic surgery. Br J Surg (2006) 1.88
Epithelial overexpression of interleukin-32alpha in inflammatory bowel disease. Clin Exp Immunol (2007) 1.87
Chromosomal assignment of the mouse kappa light chain genes. Proc Natl Acad Sci U S A (1979) 1.87
Receptors for human alpha and beta interferon but not for gamma interferon are specified by human chromosome 21. Proc Natl Acad Sci U S A (1984) 1.86
Immunohistochemical and subcellular localization of Parkin protein: absence of protein in autosomal recessive juvenile parkinsonism patients. Ann Neurol (1999) 1.86
Observations on cholera treated orally and intravenously with antibiotics. With particular reference to the number of vibrios excreted in the stool. Bull World Health Organ (1967) 1.85
Chromophore/protein interaction in bacterial sensory rhodopsin and bacteriorhodopsin. Biophys J (1986) 1.83
Human chromosome 7 carries the beta 2 interferon gene. Proc Natl Acad Sci U S A (1986) 1.82
Starch gel electrophoretic phenotypes of mouse times human somatic cell hybrids and mouse isozyme polymorphisms. In Vitro (1974) 1.81
Two homoeo box loci mapped in evolutionarily related mouse and human chromosomes. Nature (1985) 1.81
Molecular cloning of a novel putative Ca2+ channel protein (TRPC7) highly expressed in brain. Genomics (1998) 1.80
A new vector for recombination-based cloning of large DNA fragments from yeast artificial chromosomes. Nucleic Acids Res (1995) 1.80
A novel myosin-like protein (myocilin) expressed in the connecting cilium of the photoreceptor: molecular cloning, tissue expression, and chromosomal mapping. Genomics (1997) 1.80
A new electrophoretic-autoradiographic method for the visual detection of phosphotransferases. Anal Biochem (1973) 1.78
One-megabase sequence analysis of the human immunoglobulin lambda gene locus. Genome Res (1997) 1.77
Chromosomal location of the structural gene cluster encoding murine immunoglobulin heavy chains. J Exp Med (1980) 1.76
The medaka rs-3 locus required for scale development encodes ectodysplasin-A receptor. Curr Biol (2001) 1.75
Establishment of a new system for determination of coreceptor usages of HIV based on the human glioma NP-2 cell line. Biochem Biophys Res Commun (1999) 1.75
Chromosome-mediated gene transfer results in two classes of unstable transformants. Proc Natl Acad Sci U S A (1980) 1.74
Co-transfer of human X-linked markers into murine somatic cells via isolated metaphase chromosomes. Proc Natl Acad Sci U S A (1978) 1.73
Phenotype stabilisation and integration of transferred material in chromosome-mediated gene transfer. Nature (1979) 1.73
Genetic analysis with man-mouse somatic cell hybrids. Linkage between human lactate dehydrogenase A and B and peptidase B. Nature (1970) 1.73
An efficient cis-element discovery method using multiple sequence comparisons based on evolutionary relationships. Genomics (2001) 1.72
Sequence analysis of the murine Hox-2.2, -2.3, and -2.4 homeo boxes: evolutionary and structural comparisons. Genomics (1987) 1.71
Isolation and initial characterization of a novel zinc finger gene, DNMT3L, on 21q22.3, related to the cytosine-5-methyltransferase 3 gene family. Genomics (2000) 1.70
Multiplex gene regulation: a two-tiered approach to transgene regulation in transgenic mice. Proc Natl Acad Sci U S A (1989) 1.69
Genetic control of two electrophoretic variants of glucosephosphate isomerase in the mouse (Mus musculus). Biochem Genet (1969) 1.69
Epstein-Barr virus infection of human gastric carcinoma cells: implication of the existence of a new virus receptor different from CD21. J Virol (1997) 1.69
Karyotype analysis utilizing differentially stained constitutive heterochromatin of human and murine chromosomes. Chromosoma (1971) 1.68
Cotransfer of thymidine kinase and galactokinase genes by chromosome-mediated gene transfer. Proc Natl Acad Sci U S A (1978) 1.67
Chromosome polymorphism in American Negro and White populations. Nature (1971) 1.66
The evolution of the vertebrate Dlx gene family. Proc Natl Acad Sci U S A (1996) 1.64
Chromosomal abnormalities in the human population: estimation of rates based on New Haven newborn study. Science (1970) 1.64
Biological detection of specific mRNA molecules by microinjection. Proc Natl Acad Sci U S A (1979) 1.63
Cloning and expression of murine lymphotoxin cDNA. J Immunol (1987) 1.62
Parasexual approaches to the genetics of man. Annu Rev Genet (1975) 1.62
Genetic complementation in heterokaryons of human fibroblasts defective in cobalamin metabolism. Proc Natl Acad Sci U S A (1975) 1.62
Absorption of pathogenic autoantibodies by the extracellular domain of pemphigus vulgaris antigen (Dsg3) produced by baculovirus. J Clin Invest (1994) 1.62
PTEN activity could be a predictive marker of trastuzumab efficacy in the treatment of ErbB2-overexpressing breast cancer. Br J Cancer (2006) 1.61
Expression of liver phenotypes in cultured mouse hepatoma cells. J Natl Cancer Inst (1980) 1.60
Use of multiplex PCR and real-time PCR to detect human herpes virus genome in ocular fluids of patients with uveitis. Br J Ophthalmol (2008) 1.60
Pluripotent teratocarcinoma-thymus somatic cell hybrids. Cell (1976) 1.60
Mouse-human heterokaryon analysis with a 33258 Hoechst-Giemsa technique. J Cell Biol (1975) 1.59