Published in Gene on October 25, 1981
Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences. EMBO J (1991) 23.69
Patterns of integration of DNA microinjected into cultured mammalian cells: evidence for homologous recombination between injected plasmid DNA molecules. Mol Cell Biol (1982) 7.49
Encapsidation sequences for spleen necrosis virus, an avian retrovirus, are between the 5' long terminal repeat and the start of the gag gene. Proc Natl Acad Sci U S A (1982) 5.56
Mechanisms of DNA uptake by mammalian cells: fate of exogenously added DNA monitored by the use of fluorescent dyes. Proc Natl Acad Sci U S A (1982) 5.30
Bovine papillomavirus vector that propagates as a plasmid in both mouse and bacterial cells. Proc Natl Acad Sci U S A (1982) 4.69
Extrachromosomal DNA transformation of Caenorhabditis elegans. Mol Cell Biol (1985) 4.37
Structure and expression of a mouse major histocompatibility antigen gene, H-2Ld. Proc Natl Acad Sci U S A (1982) 3.73
Cre-stimulated recombination at loxP-containing DNA sequences placed into the mammalian genome. Nucleic Acids Res (1989) 3.63
Transformation of Tetrahymena thermophila by microinjection of ribosomal RNA genes. Proc Natl Acad Sci U S A (1986) 2.75
Novel use of synthetic oligonucleotide insertion mutants for the study of homologous recombination in mammalian cells. Proc Natl Acad Sci U S A (1983) 2.67
Versatile cosmid vectors for the isolation, expression, and rescue of gene sequences: studies with the human alpha-globin gene cluster. Proc Natl Acad Sci U S A (1983) 2.14
Homologous recombination between overlapping thymidine kinase gene fragments stably inserted into a mouse cell genome. Mol Cell Biol (1984) 1.88
Gene shuttling: moving of cloned DNA into and out of eukaryotic cells. Nucleic Acids Res (1982) 1.85
Stable transformation of mouse L cells for human membrane T-cell differentiation antigens, HLA and beta 2-microglobulin: selection by fluorescence-activated cell sorting. Proc Natl Acad Sci U S A (1983) 1.80
Vectors containing a prokaryotic dihydrofolate reductase gene transform Drosophila cells to methotrexate-resistance. EMBO J (1983) 1.74
Inducer-responsive expression of the cloned human interferon beta 1 gene introduced into cultured mouse cells. Nucleic Acids Res (1982) 1.69
Stable transformation of tobacco by electroporation: evidence for plasmid concatenation. Proc Natl Acad Sci U S A (1986) 1.61
Intrachromosomal recombination in plants. EMBO J (1990) 1.40
Expression of adenovirus E1a and E1b gene products and the Escherichia coli XGPRT gene in KB cells. J Virol (1983) 1.39
Expression of transferred thymidine kinase genes is controlled by methylation. Proc Natl Acad Sci U S A (1982) 1.39
DNA-mediated gene transfer without carrier DNA. J Cell Biol (1981) 1.25
Asbestos fibers mediate transformation of monkey cells by exogenous plasmid DNA. Proc Natl Acad Sci U S A (1988) 1.14
Sequences involved in the regulated expression of the human interferon-beta1 gene in recombinant SV40 DNA vectors replicating in monkey cells. EMBO J (1983) 1.14
ADP-ribosylation is involved in the integration of foreign DNA into the mammalian cell genome. Nucleic Acids Res (1988) 1.12
Cycloheximide induces expression of the human interferon beta 1 gene in mouse cells transformed by bovine papillomavirus-interferon beta 1 recombinants. J Virol (1983) 1.08
BK virus-plasmid expression vector that persists episomally in human cells and shuttles into Escherichia coli. Mol Cell Biol (1984) 1.06
Fate of exogenous recombinant plasmids introduced into mouse and human cells. Nucleic Acids Res (1985) 1.06
Procaryotic genomic DNA inhibits mammalian cell transformation. Mol Cell Biol (1983) 0.94
Homologous recombination and the repair of double-strand breaks during cotransformation of Dictyostelium discoideum. Mol Cell Biol (1988) 0.90
Regulated expression of a Drosophila melanogaster heat shock locus after stable integration in a Drosophila hydei cell line. Mol Cell Biol (1985) 0.85
Enhancement of DNA-mediated gene transfer by high-Mr carrier DNA in synchronized CV-1 cells. Biochem J (1985) 0.85
Transfection by genomic DNA of cytochrome P1-450 enzymatic activity and inducibility. Mol Cell Biol (1985) 0.84
The uptake and stability of simian-virus-40 DNA after calcium phosphate transfection of CV-1 cells. Biochem J (1984) 0.80
Efficient functioning of plant promoters and poly(A) sites in Xenopus oocytes. Nucleic Acids Res (1989) 0.79
Differential expression of porcine major histocompatibility DNA sequences introduced into mouse L cells. Mol Cell Biol (1983) 0.78
Transfection of normal human and Chinese hamster DNA corrects diepoxybutane-induced chromosomal hypersensitivity of Fanconi anemia fibroblasts. Proc Natl Acad Sci U S A (1987) 0.77
Genetic engineering: moral aspects and control of practice. J Assist Reprod Genet (1997) 0.75
Genetic transformation of mouse embryos by microinjection of purified DNA. Proc Natl Acad Sci U S A (1980) 5.47
The status of the gene map of the human chromosomes. Science (1977) 5.44
Mechanisms of DNA uptake by mammalian cells: fate of exogenously added DNA monitored by the use of fluorescent dyes. Proc Natl Acad Sci U S A (1982) 5.30
Somatic cell genetics and gene families. Science (1983) 4.61
Recombination during gene transfer into mouse cells can restore the function of deleted genes. Science (1983) 4.32
A conversational system for the computer analysis of nucleic acid sequences. Nucleic Acids Res (1981) 4.07
Transfer of the human gene for hypoxanthine-guanine phosphoribosyltransferase via isolated human metaphase chromosomes into mouse L-cells. Proc Natl Acad Sci U S A (1975) 3.91
Use of a protein-blotting procedure and a specific DNA probe to identify nuclear proteins that recognize the promoter region of the transferrin receptor gene. Proc Natl Acad Sci U S A (1985) 3.91
Gene transfer, expression, and molecular cloning of the human transferrin receptor gene. Cell (1984) 3.42
A review of enzyme polymorphism, linkage and electrophoretic conditions for mouse and somatic cell hybrids in starch gels. J Histochem Cytochem (1973) 3.33
Human nucleolus organizers on nonhomologous chromosomes can share the same ribosomal gene variants. Proc Natl Acad Sci U S A (1981) 3.21
The human transferrin receptor gene: genomic organization, and the complete primary structure of the receptor deduced from a cDNA sequence. Cell (1984) 3.14
Molecular cloning and chromosome mapping of a mouse DNA sequence homologous to homeotic genes of Drosophila. Cell (1984) 2.89
Controlled production of proliferating somatic cell hybrids. J Cell Biol (1970) 2.78
Mammalian Trithorax and polycomb-group homologues are antagonistic regulators of homeotic development. Proc Natl Acad Sci U S A (1999) 2.76
A sequential staining technique for the chromosomal analysis of the interspecific mouse/hamster and mouse/human somatic cell hybrids. Exp Cell Res (1977) 2.71
Chromosomal localization of human beta globin gene on human chromosome 11 in somatic cell hybrids. Proc Natl Acad Sci U S A (1978) 2.65
Regional mapping of the phenylalanine hydroxylase gene and the phenylketonuria locus in the human genome. Proc Natl Acad Sci U S A (1985) 2.58
International system for human gene nomenclature (1979) ISGN (1979). Cytogenet Cell Genet (1979) 2.58
The linkage of genes for the human interferon-induced antiviral protein and indophenol oxidase-B traits to chromosome G-21. J Exp Med (1973) 2.57
Linkage analysis in man by somatic cell genetics. Nature (1973) 2.33
Integration and stable germ line transmission of genes injected into mouse pronuclei. Science (1981) 2.31
Gene transfer into mouse embryos: production of transgenic mice by pronuclear injection. Methods Enzymol (1983) 2.23
Two steps in the evolution of Antennapedia-class vertebrate homeobox genes. Proc Natl Acad Sci U S A (1989) 2.23
Spatial restriction in expression of a mouse homoeo box locus within the central nervous system. Nature (1986) 2.16
Molecular cloning and structural analysis of murine thymidine kinase genomic and cDNA sequences. Mol Cell Biol (1985) 2.13
Gene linkage analysis in the mouse by somatic cell hybridization: assignment of adenine phosphoribosyltransferase to chromosome 8 and alpha-galactosidase to the X chromosome. Somatic Cell Genet (1975) 2.11
Prevention of allogeneic bone marrow graft rejection by H-2 transgene in donor mice. Science (1989) 2.08
Chromosomal location of structural genes encoding murine immunoglobulin lambda light chains. Genetics of murine lambda light chains. J Exp Med (1981) 2.07
DNA-mediated gene transfer of a circular plasmid into murine cells. Proc Natl Acad Sci U S A (1979) 2.02
Differential staining of interspecific chromosomes in somatic cell hybrids by alkaline Giemsa stain. Somatic Cell Genet (1976) 1.98
Microcell-mediated transfer of murine chromosomes into mouse, Chinese hamster, and human somatic cells. Proc Natl Acad Sci U S A (1977) 1.97
Assignment of the gene for adenine phosphoribosyltransferase to human chromosome 16 by mouse-human somatic cell hybridization. Proc Natl Acad Sci U S A (1974) 1.97
Glutamate oxalate transaminase (GOT) genetics in Mus musculus: linkage, polymorphism, and phenotypes of the Got-2 and Got-1 loci. Biochem Genet (1970) 1.96
A new era in mammalian gene mapping: somatic cell genetics and recombinant DNA methodologies. Nature (1981) 1.96
Human chromosome 21 dosage: effect on the expression of the interferon induced antiviral state. Science (1974) 1.95
Assignment of three human genes to chromosomes (LDH-A to 11, TK to 17, and IDH to 20) and evidence for translocation between human and mouse chromosomes in somatic cell hybrids (thymidine kinase-lactate dehydrogenase A-isocitrate dehydrogenase-C-11, E-17, and F-20 chromosomes). Proc Natl Acad Sci U S A (1972) 1.93
Homeo box gene complex on mouse chromosome 11: molecular cloning, expression in embryogenesis, and homology to a human homeo box locus. Cell (1985) 1.92
Chromosomal assignment of the mouse kappa light chain genes. Proc Natl Acad Sci U S A (1979) 1.87
Receptors for human alpha and beta interferon but not for gamma interferon are specified by human chromosome 21. Proc Natl Acad Sci U S A (1984) 1.86
Human chromosome 7 carries the beta 2 interferon gene. Proc Natl Acad Sci U S A (1986) 1.82
Two homoeo box loci mapped in evolutionarily related mouse and human chromosomes. Nature (1985) 1.81
Starch gel electrophoretic phenotypes of mouse times human somatic cell hybrids and mouse isozyme polymorphisms. In Vitro (1974) 1.81
A new vector for recombination-based cloning of large DNA fragments from yeast artificial chromosomes. Nucleic Acids Res (1995) 1.80
A new electrophoretic-autoradiographic method for the visual detection of phosphotransferases. Anal Biochem (1973) 1.78
Chromosomal location of the structural gene cluster encoding murine immunoglobulin heavy chains. J Exp Med (1980) 1.76
Chromosome-mediated gene transfer results in two classes of unstable transformants. Proc Natl Acad Sci U S A (1980) 1.74
Co-transfer of human X-linked markers into murine somatic cells via isolated metaphase chromosomes. Proc Natl Acad Sci U S A (1978) 1.73
Phenotype stabilisation and integration of transferred material in chromosome-mediated gene transfer. Nature (1979) 1.73
Genetic analysis with man-mouse somatic cell hybrids. Linkage between human lactate dehydrogenase A and B and peptidase B. Nature (1970) 1.73
An efficient cis-element discovery method using multiple sequence comparisons based on evolutionary relationships. Genomics (2001) 1.72
Sequence analysis of the murine Hox-2.2, -2.3, and -2.4 homeo boxes: evolutionary and structural comparisons. Genomics (1987) 1.71
Multiplex gene regulation: a two-tiered approach to transgene regulation in transgenic mice. Proc Natl Acad Sci U S A (1989) 1.69
Genetic control of two electrophoretic variants of glucosephosphate isomerase in the mouse (Mus musculus). Biochem Genet (1969) 1.69
Karyotype analysis utilizing differentially stained constitutive heterochromatin of human and murine chromosomes. Chromosoma (1971) 1.68
Cotransfer of thymidine kinase and galactokinase genes by chromosome-mediated gene transfer. Proc Natl Acad Sci U S A (1978) 1.67
Chromosome polymorphism in American Negro and White populations. Nature (1971) 1.66
The evolution of the vertebrate Dlx gene family. Proc Natl Acad Sci U S A (1996) 1.64
Chromosomal abnormalities in the human population: estimation of rates based on New Haven newborn study. Science (1970) 1.64
Biological detection of specific mRNA molecules by microinjection. Proc Natl Acad Sci U S A (1979) 1.63
Cloning and expression of murine lymphotoxin cDNA. J Immunol (1987) 1.62
Parasexual approaches to the genetics of man. Annu Rev Genet (1975) 1.62
Genetic complementation in heterokaryons of human fibroblasts defective in cobalamin metabolism. Proc Natl Acad Sci U S A (1975) 1.62
Expression of liver phenotypes in cultured mouse hepatoma cells. J Natl Cancer Inst (1980) 1.60
Pluripotent teratocarcinoma-thymus somatic cell hybrids. Cell (1976) 1.60
Mouse-human heterokaryon analysis with a 33258 Hoechst-Giemsa technique. J Cell Biol (1975) 1.59
Embryonal carcinoma cells (and their somatic cell hybrids) are resistant to infection by the murine parvovirus MVM, which does infect other teratocarcinoma-derived cell lines. J Cell Physiol (1977) 1.58
Detection of homeobox genes in development and evolution. Proc Natl Acad Sci U S A (1991) 1.55
A herpes simplex virus 1 integration site in the mouse genome defined by somatic cell genetic analysis. Cell (1978) 1.54
Cyclic changes in enzyme activity in synchronized mammalian cell cultures. Science (1968) 1.53
Chromosomal assignment of a family of human oncogenes. Proc Natl Acad Sci U S A (1983) 1.53
Expansion of the Hox gene family and the evolution of chordates. Proc Natl Acad Sci U S A (1993) 1.52
Assignment of a gene for adenosine deaminase to human chromosome 20. Hum Hered (1974) 1.52
The William Allan Memorial Award address: Reverse genetics and beyond. Am J Hum Genet (1984) 1.52
DNA sequence associated with chromosome translocations in mouse plasmacytomas. Proc Natl Acad Sci U S A (1982) 1.51
Assignment of nucleoside phosphorylase to D-14 and localization of X-linked loci in man by somatic cell genetics. Nat New Biol (1973) 1.51
Tay-Sachs' and Sandhoff's diseases: the assignment of genes for hexosaminidase A and B to individual human chromosomes. Proc Natl Acad Sci U S A (1975) 1.49
Fibroblast interferon in man is coded by two loci on separate chromosomes. Cell (1979) 1.49
Assignment of the gene for galactokinase to human chromosome 17 and its regional localisation to band q21-22. Nature (1974) 1.49
Deoxyribonucleic acid-mediated gene transfer in mammalian cells: molecular analysis of unstable transformants and their progression to stability. Mol Cell Biol (1981) 1.47
The somatic cell genetics of human interferon: assignment of human interferon loci to chromosomes 2 and 5. Proc Natl Acad Sci U S A (1974) 1.46
Stable association of the human transgenome and host murine chromosomes demonstrated with trispecific microcell hybrids. Proc Natl Acad Sci U S A (1977) 1.45
Regulated expression of a murine class I gene in transgenic mice. Mol Cell Biol (1986) 1.44
The genes coding for the muscle contractile proteins, myosin heavy chain, myosin light chain 2, and skeletal muscle actin are located on three different mouse chromosomes. EMBO J (1982) 1.44
Isolation, chromosomal localization, and nucleotide sequence of the human HOX 1.4 homeobox. Genomics (1989) 1.43
The PKU locus in man is on chromosome 12. Am J Hum Genet (1984) 1.42
Transcriptional regulation by iron of the gene for the transferrin receptor. Mol Cell Biol (1986) 1.42
Localization and induction of the human thymidine kinase gene by adenovirus 12. Nat New Biol (1973) 1.42
Murine alpha-fetoprotein and albumin: two evolutionarily linked proteins encoded on the same mouse chromosome. Somatic Cell Genet (1981) 1.41
Phylogenetic reconstruction of vertebrate Hox cluster duplications. Mol Biol Evol (1997) 1.41
Identification of human genomic clones coding the major histocompatibility antigens HLA-a2 and HLA-B7 by DNA-mediated gene transfer. Proc Natl Acad Sci U S A (1982) 1.39
Expression of transferred thymidine kinase genes is controlled by methylation. Proc Natl Acad Sci U S A (1982) 1.39
Linkage of isozyyme loci in the mouse: phosphoglucomutase-2 (Pgm-2), mitochondrial NADP malate dehydrogenase (Mod-2), and dipeptidase-1 (Dip-1). Biochem Genet (1971) 1.37
Linkage analysis using somatic cell hybrids. Adv Hum Genet (1972) 1.36
Modification of expression and cis-regulation of Hoxc8 in the evolution of diverged axial morphology. Proc Natl Acad Sci U S A (1998) 1.36
Antibodies to a cell-surface component coded by human chromosome 21 inhibit action of interferon. Nature (1976) 1.35
Natural resistance against lymphoma grafts conveyed by H-2Dd transgene to C57BL mice. J Exp Med (1988) 1.34
Mitochondrial malate dehydrogenase and malic enzyme: Mendelian inherited electrophoretic variants in the mouse. Biochem Genet (1970) 1.33
Localization of the casein gene family to a single mouse chromosome. J Cell Biol (1982) 1.33