Published in J Biol Chem on May 15, 1987
Novel non-templated nucleotide addition reactions catalyzed by procaryotic and eucaryotic DNA polymerases. Nucleic Acids Res (1988) 15.37
Comparison between DNA melting thermodynamics and DNA polymerase fidelity. Proc Natl Acad Sci U S A (1988) 4.07
A thymidine triphosphate shape analog lacking Watson-Crick pairing ability is replicated with high sequence selectivity. Proc Natl Acad Sci U S A (1997) 2.85
Proliferating cell nuclear antigen-dependent abasic site repair in Xenopus laevis oocytes: an alternative pathway of base excision DNA repair. Mol Cell Biol (1994) 2.42
Difluorotoluene, a Nonpolar Isostere for Thymine, Codes Specifically and Efficiently for Adenine in DNA Replication. J Am Chem Soc (1997) 2.37
Mutation frequency and spectrum resulting from a single abasic site in a single-stranded vector. Nucleic Acids Res (1990) 2.29
Biochemical basis of SOS-induced mutagenesis in Escherichia coli: reconstitution of in vitro lesion bypass dependent on the UmuD'2C mutagenic complex and RecA protein. Proc Natl Acad Sci U S A (1998) 2.22
Activity of the purified mutagenesis proteins UmuC, UmuD', and RecA in replicative bypass of an abasic DNA lesion by DNA polymerase III. Proc Natl Acad Sci U S A (1992) 2.03
Mutagenic potentials of damaged nucleic acids produced by reactive oxygen/nitrogen species: approaches using synthetic oligonucleotides and nucleotides: survey and summary. Nucleic Acids Res (2003) 1.73
Reverse chemical mutagenesis: identification of the mutagenic lesions resulting from reactive oxygen species-mediated damage to DNA. Proc Natl Acad Sci U S A (1994) 1.69
An abasic site in DNA. Solution conformation determined by proton NMR and molecular mechanics calculations. Nucleic Acids Res (1987) 1.47
Bypass and termination at apurinic sites during replication of single-stranded DNA in vitro: a model for apurinic site mutagenesis. Proc Natl Acad Sci U S A (1988) 1.39
Proliferating cell nuclear antigen promotes DNA synthesis past template lesions by mammalian DNA polymerase delta. Proc Natl Acad Sci U S A (1997) 1.38
Specificity of the mutator caused by deletion of the yeast structural gene (APN1) for the major apurinic endonuclease. Proc Natl Acad Sci U S A (1994) 1.36
DNA sequence analysis of spontaneous mutagenesis in Saccharomyces cerevisiae. Genetics (1998) 1.35
Influence of abasic and anucleosidic sites on the stability, conformation, and melting behavior of a DNA duplex: correlations of thermodynamic and structural data. Proc Natl Acad Sci U S A (1989) 1.31
8-Hydroxyadenine (7,8-dihydro-8-oxoadenine) induces misincorporation in in vitro DNA synthesis and mutations in NIH 3T3 cells. Nucleic Acids Res (1995) 1.26
Biological properties of single chemical-DNA adducts: a twenty year perspective. Chem Res Toxicol (2007) 1.24
Disruption of the RAD52 gene alters the spectrum of spontaneous SUP4-o mutations in Saccharomyces cerevisiae. Genetics (1989) 1.23
DNA polymerase II of Escherichia coli in the bypass of abasic sites in vivo. Genetics (1994) 1.21
Human cells contain protein specifically binding to a single 1,N6-ethenoadenine in a DNA fragment. Proc Natl Acad Sci U S A (1991) 1.19
Replication through an abasic DNA lesion: structural basis for adenine selectivity. EMBO J (2010) 1.16
Mechanism of mutation on DNA templates containing synthetic abasic sites: study with a double strand vector. Nucleic Acids Res (1994) 1.15
Difference between deoxyribose- and tetrahydrofuran-type abasic sites in the in vivo mutagenic responses in yeast. Nucleic Acids Res (2002) 1.12
DNA oligonucleotides with A, T, G or C opposite an abasic site: structure and dynamics. Nucleic Acids Res (2007) 1.08
Mutational specificity of gamma-radiation-induced guanine-thymine and thymine-guanine intrastrand cross-links in mammalian cells and translesion synthesis past the guanine-thymine lesion by human DNA polymerase eta. Biochemistry (2008) 1.04
DNA synthesis across an abasic lesion by human DNA polymerase iota. Structure (2009) 1.04
The yeast rad18 mutator specifically increases G.C----T.A transversions without reducing correction of G-A or C-T mismatches to G.C pairs. Mol Cell Biol (1991) 1.03
An abasic site analogue activates a c-Ha-ras gene by a point mutation at modified and adjacent positions. Nucleic Acids Res (1992) 1.02
High-fidelity DNA polymerase enhances the sensitivity of a peptide nucleic acid clamp PCR assay for K-ras mutations. J Mol Diagn (2008) 1.01
Replication of DNA templates containing 5-formyluracil, a major oxidative lesion of thymine in DNA. Nucleic Acids Res (1997) 0.96
Evolving a polymerase for hydrophobic base analogues. J Am Chem Soc (2009) 0.95
Translesional synthesis on DNA templates containing the 2'-deoxyribonolactone lesion. Nucleic Acids Res (2001) 0.94
Kinetics of error generation in homologous B-family DNA polymerases. Nucleic Acids Res (2006) 0.94
DNA duplex stability: the role of preorganized electrostatics. J Phys Chem B (2010) 0.93
Replication bypass and mutagenic effect of alpha-deoxyadenosine site-specifically incorporated into single-stranded vectors. Nucleic Acids Res (1997) 0.93
Chemistry and structural biology of DNA damage and biological consequences. Chem Biodivers (2011) 0.92
The steric gate of DNA polymerase ι regulates ribonucleotide incorporation and deoxyribonucleotide fidelity. J Biol Chem (2014) 0.92
Dihydrothymidine and thymidine glycol triphosphates as substrates for DNA polymerases: differential recognition of thymine C5-C6 bond saturation and sequence specificity of incorporation. Nucleic Acids Res (1988) 0.91
The production of PCR products with 5' single-stranded tails using primers that incorporate novel phosphoramidite intermediates. Nucleic Acids Res (1993) 0.88
RB69 DNA polymerase structure, kinetics, and fidelity. Biochemistry (2014) 0.86
Contribution of partial charge interactions and base stacking to the efficiency of primer extension at and beyond abasic sites in DNA. Biochemistry (2012) 0.86
DNA synthesis across an abasic lesion by yeast REV1 DNA polymerase. J Mol Biol (2010) 0.85
Incorporation by chemical synthesis and characterization of deoxyribosylformylamine into DNA. Nucleic Acids Res (1991) 0.82
Mechanisms by which herpes simplex virus DNA polymerase limits translesion synthesis through abasic sites. DNA Repair (Amst) (2007) 0.82
Action of a mammalian AP-endonuclease on DNAs of defined sequences. Nucleic Acids Res (1989) 0.82
The effect of the 2-amino group of 7,8-dihydro-8-oxo-2'-deoxyguanosine on translesion synthesis and duplex stability. Nucleic Acids Res (2005) 0.81
Ligation-independent cloning of PCR products with primers containing nonbase residues. Nucleic Acids Res (1994) 0.81
Analysis of cleavage products of DNA repair enzymes and other nucleases. Characterization of an apurinic/apyrimidinic specific endonuclease from mouse plasmacytoma cells. Nucleic Acids Res (1988) 0.80
Amino acid templating mechanisms in selection of nucleotides opposite abasic sites by a family a DNA polymerase. J Biol Chem (2012) 0.80
Solution conformation of an oligonucleotide containing a urea deoxyribose residue in front of a thymine. Nucleic Acids Res (1992) 0.80
On the mechanism of preferential incorporation of dAMP at abasic sites in translesional DNA synthesis. Role of proofreading activity of DNA polymerase and thermodynamic characterization of model template-primers containing an abasic site. Nucleic Acids Res (1995) 0.79
Polymerase incorporation and miscoding properties of 5-chlorouracil. Chem Res Toxicol (2010) 0.79
The effects of the ring fragmentation product of thymidine C5-hydrate on phosphodiesterases and klenow (exo-) fragment. Nucleic Acids Res (1995) 0.78
Physical and functional interactions between Escherichia coli MutY and endonuclease VIII. Biochem J (2006) 0.78
Effect of sequence context and direction of replication on AP site bypass in Saccharomyces cerevisiae. Mutat Res (2009) 0.78
Blockage of polymerase-catalyzed DNA chain elongation by chemically modified cytosine residues in templates and the release of blockage for readthrough. Nucleic Acids Res (1992) 0.77
Escherichia coli exonuclease III enhances long PCR amplification of damaged DNA templates. Nucleic Acids Res (2000) 0.77
Aberrant expression of N-methylpurine-DNA glycosylase influences patient survival in malignant gliomas. J Biomed Biotechnol (2012) 0.77
The discovery of error-prone DNA polymerase V and its unique regulation by RecA and ATP. J Biol Chem (2014) 0.76
Template-directed addition of nucleosides to DNA by the BfiI restriction enzyme. Nucleic Acids Res (2008) 0.75
DNA polymerase V kinetics support the instructive nature of an oxidized abasic lesion in Escherichia coli. Biochemistry (2013) 0.75
The importance of repairing stalled replication forks. Nature (2000) 7.93
The Y-family of DNA polymerases. Mol Cell (2001) 6.49
Fidelity mechanisms in DNA replication. Annu Rev Biochem (1991) 5.93
Prenylation of oncogenic human PTP(CAAX) protein tyrosine phosphatases. Cancer Lett (1996) 5.75
Biochemical basis of DNA replication fidelity. Crit Rev Biochem Mol Biol (1993) 4.69
UmuD'(2)C is an error-prone DNA polymerase, Escherichia coli pol V. Proc Natl Acad Sci U S A (1999) 4.24
Comparison between DNA melting thermodynamics and DNA polymerase fidelity. Proc Natl Acad Sci U S A (1988) 4.07
Roles of E. coli DNA polymerases IV and V in lesion-targeted and untargeted SOS mutagenesis. Nature (2000) 3.95
Extension of base mispairs by Taq DNA polymerase: implications for single nucleotide discrimination in PCR. Nucleic Acids Res (1992) 3.74
Gel fidelity assay measuring nucleotide misinsertion, exonucleolytic proofreading, and lesion bypass efficiencies. Methods Enzymol (1995) 3.65
DNA polymerase insertion fidelity. Gel assay for site-specific kinetics. J Biol Chem (1987) 3.59
Base mispair extension kinetics. Comparison of DNA polymerase alpha and reverse transcriptase. J Biol Chem (1990) 3.38
Studies on the biochemical basis of spontaneous mutation. II. The incorporation of a base and its analogue into DNA by wild-type, mutator and antimutator DNA polymerases. J Mol Biol (1974) 2.79
Crystal structure of a DNA Holliday junction. Nat Struct Biol (1999) 2.69
Error induction and correction by mutant and wild type T4 DNA polymerases. Kinetic error discrimination mechanisms. J Biol Chem (1979) 2.53
Nearest neighbor influences on DNA polymerase insertion fidelity. J Biol Chem (1989) 2.29
Biochemical basis of SOS-induced mutagenesis in Escherichia coli: reconstitution of in vitro lesion bypass dependent on the UmuD'2C mutagenic complex and RecA protein. Proc Natl Acad Sci U S A (1998) 2.22
Properties of the partially purified tonoplast H+-pumping ATPase from oat roots. J Biol Chem (1986) 2.16
Base pairing and mutagenesis: observation of a protonated base pair between 2-aminopurine and cytosine in an oligonucleotide by proton NMR. Proc Natl Acad Sci U S A (1986) 2.09
Activity of the purified mutagenesis proteins UmuC, UmuD', and RecA in replicative bypass of an abasic DNA lesion by DNA polymerase III. Proc Natl Acad Sci U S A (1992) 2.03
Purification and characterization of an inducible Escherichia coli DNA polymerase capable of insertion and bypass at abasic lesions in DNA. J Biol Chem (1988) 1.97
Comparison of HIV-1 and avian myeloblastosis virus reverse transcriptase fidelity on RNA and DNA templates. J Biol Chem (1992) 1.96
DNA polymerase II is encoded by the DNA damage-inducible dinA gene of Escherichia coli. Proc Natl Acad Sci U S A (1990) 1.95
Spectroscopic and calorimetric characterizations of DNA duplexes containing 2-aminopurine. Biochemistry (1996) 1.88
Proofreading-defective DNA polymerase II increases adaptive mutation in Escherichia coli. Proc Natl Acad Sci U S A (1995) 1.85
Abasic translesion synthesis by DNA polymerase beta violates the "A-rule". Novel types of nucleotide incorporation by human DNA polymerase beta at an abasic lesion in different sequence contexts. J Biol Chem (1997) 1.83
The abasic site as a challenge to DNA polymerase. A nuclear magnetic resonance study of G, C and T opposite a model abasic site. J Mol Biol (1990) 1.81
Comparison of nucleotide interactions in water, proteins, and vacuum: model for DNA polymerase fidelity. Proc Natl Acad Sci U S A (1986) 1.80
Direct detection of HIV-1 RNA from AIDS and ARC patient samples. DNA (1988) 1.79
Influence of neighboring bases on DNA polymerase insertion and proofreading fidelity. J Biol Chem (1985) 1.78
Inhibition of human immunodeficiency virus by using an oligonucleoside methylphosphonate targeted to the tat-3 gene. J Virol (1988) 1.73
Crystal structure of a DinB family error-prone DNA polymerase from Sulfolobus solfataricus. Nat Struct Biol (2001) 1.72
Processive DNA synthesis by DNA polymerase II mediated by DNA polymerase III accessory proteins. J Biol Chem (1992) 1.72
Fidelity of Escherichia coli DNA polymerase III holoenzyme. The effects of beta, gamma complex processivity proteins and epsilon proofreading exonuclease on nucleotide misincorporation efficiencies. J Biol Chem (1997) 1.70
A phenotype for enigmatic DNA polymerase II: a pivotal role for pol II in replication restart in UV-irradiated Escherichia coli. Proc Natl Acad Sci U S A (1999) 1.69
A novel p34(cdc2)-binding and activating protein that is necessary and sufficient to trigger G(2)/M progression in Xenopus oocytes. Genes Dev (1999) 1.66
Pre-steady-state kinetic analysis of sequence-dependent nucleotide excision by the 3'-exonuclease activity of bacteriophage T4 DNA polymerase. Biochemistry (1994) 1.65
On the fidelity of DNA replication. The accuracy of T4 DNA polymerases in copying phi X174 DNA in vitro. J Biol Chem (1984) 1.65
Mechanism of human methyl-directed DNA methyltransferase and the fidelity of cytosine methylation. Proc Natl Acad Sci U S A (1992) 1.64
The structure of plasmid-encoded transcriptional repressor CopG unliganded and bound to its operator. EMBO J (1998) 1.64
Purification of a soluble UmuD'C complex from Escherichia coli. Cooperative binding of UmuD'C to single-stranded DNA. J Biol Chem (1996) 1.64
Identification of a DinB/UmuC homolog in the archeon Sulfolobus solfataricus. Mutat Res (1996) 1.61
Recognition of unusual DNA structures by human DNA (cytosine-5)methyltransferase. J Mol Biol (1991) 1.61
Involvement of Escherichia coli DNA polymerase II in response to oxidative damage and adaptive mutation. J Bacteriol (1994) 1.60
A compact system of small planets around a former red-giant star. Nature (2011) 1.60
Synthesis and properties of oligonucleotides containing 2'-deoxynebularine and 2'-deoxyxanthosine. Nucleic Acids Res (1986) 1.60
Stability of intrastrand hairpin structures formed by the CAG/CTG class of DNA triplet repeats associated with neurological diseases. Nucleic Acids Res (1996) 1.59
Synthesis and properties of defined DNA oligomers containing base mispairs involving 2-aminopurine. Nucleic Acids Res (1986) 1.57
Enthalpy-entropy compensation in DNA melting thermodynamics. J Biol Chem (1995) 1.54
Amplification of padlock probes for DNA diagnostics by cascade rolling circle amplification or the polymerase chain reaction. Arch Pathol Lab Med (1999) 1.49
An abasic site in DNA. Solution conformation determined by proton NMR and molecular mechanics calculations. Nucleic Acids Res (1987) 1.47
Peripheral and integral subunits of the tonoplast H+-ATPase from oat roots. J Biol Chem (1988) 1.46
On the enzymatic basis for mutagenesis by manganese. J Biol Chem (1983) 1.42
Mutation induced by DNA damage: a many protein affair. Mutat Res (1990) 1.41
A model for SOS-lesion-targeted mutations in Escherichia coli. Nature (2001) 1.41
Analysis of strand slippage in DNA polymerase expansions of CAG/CTG triplet repeats associated with neurodegenerative disease. J Biol Chem (1998) 1.41
Purification and properties of wild-type and exonuclease-deficient DNA polymerase II from Escherichia coli. J Biol Chem (1995) 1.40
Influence of 5'-nearest neighbors on the insertion kinetics of the fluorescent nucleotide analog 2-aminopurine by Klenow fragment. Biochemistry (1993) 1.39
Molecular and general genetics of a hybrid foreign gene introduced into tobacco by direct gene transfer. Mol Gen Genet (1985) 1.37
Mitochondrial precursor protein. Effects of 70-kilodalton heat shock protein on polypeptide folding, aggregation, and import competence. J Biol Chem (1990) 1.37
Base analog and neighboring base effects on substrate specificity of recombinant human G:T mismatch-specific thymine DNA-glycosylase. Biochemistry (1996) 1.32
Mutation of the cyclin-dependent kinase phosphorylation site in simian virus 40 (SV40) large T antigen specifically blocks SV40 origin DNA unwinding. J Virol (1993) 1.30
Error-prone candidates vie for somatic mutation. J Exp Med (2000) 1.27
Roles of DNA polymerases V and II in SOS-induced error-prone and error-free repair in Escherichia coli. Proc Natl Acad Sci U S A (2001) 1.27
Kinetics of extension of O6-methylguanine paired with cytosine or thymine in defined oligonucleotide sequences. Biochemistry (1991) 1.26
Effect of 3' flanking neighbors on kinetics of pairing of dCTP or dTTP opposite O6-methylguanine in a defined primed oligonucleotide when Escherichia coli DNA polymerase I is used. Proc Natl Acad Sci U S A (1989) 1.26
Chimeric DNA-RNA hammerhead ribozymes have enhanced in vitro catalytic efficiency and increased stability in vivo. Nucleic Acids Res (1992) 1.24
A model for Escherichia coli DNA polymerase III holoenzyme assembly at primer/template ends. DNA triggers a change in binding specificity of the gamma complex clamp loader. J Biol Chem (2000) 1.24
Spontaneous and UV-induced mutations in Escherichia coli K-12 strains with altered or absent DNA polymerase I. J Bacteriol (1989) 1.24
Escherichia coli DNA polymerase II catalyzes chromosomal and episomal DNA synthesis in vivo. Proc Natl Acad Sci U S A (1997) 1.24
First record and establishment of the mosquito Aedes albopictus in Spain. Med Vet Entomol (2006) 1.23
Base mispair extension kinetics. Binding of avian myeloblastosis reverse transcriptase to matched and mismatched base pair termini. J Biol Chem (1992) 1.22
On the molecular basis of transition mutations: frequencies of forming 2-aminopurine.cytosine and adenine.cytosine base mispairs in vitro. Proc Natl Acad Sci U S A (1981) 1.22
Inhibition of lung injury, inflammation, and interstitial pulmonary fibrosis by polyethylene glycol-conjugated catalase in a rapid inhalation model of asbestosis. Am Rev Respir Dis (1990) 1.22
The fidelity of base selection by the polymerase subunit of DNA polymerase III holoenzyme. Nucleic Acids Res (1988) 1.22
Gel kinetic analysis of DNA polymerase fidelity in the presence of proofreading using bacteriophage T4 DNA polymerase. J Biol Chem (1995) 1.22
Three-dimensional crystal structure of the A-tract DNA dodecamer d(CGCAAATTTGCG) complexed with the minor-groove-binding drug Hoechst 33258. Eur J Biochem (1994) 1.20