Published in Nucleic Acids Res on October 24, 1986
5-Nitroindole as an universal base analogue. Nucleic Acids Res (1994) 2.78
Difluorotoluene, a Nonpolar Isostere for Thymine, Codes Specifically and Efficiently for Adenine in DNA Replication. J Am Chem Soc (1997) 2.37
Aromatic Nonpolar Nucleosides as Hydrophobic Isosteres of Pyrimidine and Purine Nucleosides. J Org Chem (1994) 2.12
Mutagenic potentials of damaged nucleic acids produced by reactive oxygen/nitrogen species: approaches using synthetic oligonucleotides and nucleotides: survey and summary. Nucleic Acids Res (2003) 1.73
Effect of 3' flanking neighbors on kinetics of pairing of dCTP or dTTP opposite O6-methylguanine in a defined primed oligonucleotide when Escherichia coli DNA polymerase I is used. Proc Natl Acad Sci U S A (1989) 1.26
Highly Precise Shape Mimicry by a Difluorotoluene Deoxynucleoside, a Replication-Competent Substitute for Thymidine. Angew Chem Int Ed Engl (1997) 1.14
Novel repair activities of AlkA (3-methyladenine DNA glycosylase II) and endonuclease VIII for xanthine and oxanine, guanine lesions induced by nitric oxide and nitrous acid. Nucleic Acids Res (2002) 1.05
The synthesis and properties of oligodeoxyribonucleotides containing N6-methoxyadenine. Nucleic Acids Res (1992) 1.03
Stability of 2'-deoxyxanthosine in DNA. Nucleic Acids Res (2003) 1.03
Biochemical characterization of a novel hypoxanthine/xanthine dNTP pyrophosphatase from Methanococcus jannaschii. Nucleic Acids Res (2001) 1.00
DNA containing the base analogue 2-aminoadenine: preparation, use as hybridization probes and cleavage by restriction endonucleases. Nucleic Acids Res (1988) 0.97
The influence of exocyclic substituents of purine bases on DNA curvature. Proc Natl Acad Sci U S A (1987) 0.95
Mechanisms of base selection by the Escherichia coli mispaired uracil glycosylase. J Biol Chem (2008) 0.94
Hypoxanthine incorporation is nonmutagenic in Escherichia coli. J Bacteriol (2006) 0.90
Steric and electrostatic effects at the C2 atom substituent influence replication and miscoding of the DNA deamination product deoxyxanthosine and analogs by DNA polymerases. J Mol Biol (2009) 0.89
Template directed incorporation of nucleotide mixtures using azole-nucleobase analogs. Nucleic Acids Res (1997) 0.89
NMR structure of a DNA duplex containing nucleoside analog 1-(2'-deoxy-beta-D-ribofuranosyl)-3-nitropyrrole and the structure of the unmodified control. Nucleic Acids Res (2000) 0.86
Role of pK(a) of nucleobases in the origins of chemical evolution. Acc Chem Res (2012) 0.86
DNA ligases ensure fidelity by interrogating minor groove contacts. Nucleic Acids Res (2004) 0.84
Covalent capture of a human O(6)-alkylguanine alkyltransferase-DNA complex using N(1),O(6)-ethanoxanthosine, a mechanism-based crosslinker. Nucleic Acids Res (2001) 0.82
An altered-specificity mutation in a human POU domain demonstrates functional analogy between the POU-specific subdomain and phage lambda repressor. Proc Natl Acad Sci U S A (1994) 0.81
Aromatic N versus aromatic F: bioisosterism discovered in RNA base pairing interactions leads to a novel class of universal base analogs. Nucleic Acids Res (2010) 0.80
Mispair formation in DNA can involve rare tautomeric forms in the template. Nucleic Acids Res (1988) 0.79
Sequencing end-labeled DNA with base-specific chemical cleavages. Methods Enzymol (1980) 287.68
Polymer support oligonucleotide synthesis XVIII: use of beta-cyanoethyl-N,N-dialkylamino-/N-morpholino phosphoramidite of deoxynucleosides for the synthesis of DNA fragments simplifying deprotection and isolation of the final product. Nucleic Acids Res (1984) 12.11
Pyrimidine-specific chemical reactions useful for DNA sequencing. Nucleic Acids Res (1980) 9.12
Use of synthetic oligonucleotides as hybridization probes: isolation of cloned cDNA sequences for human beta 2-microglobulin. Proc Natl Acad Sci U S A (1981) 7.24
Base-base mismatches. Thermodynamics of double helix formation for dCA3XA3G + dCT3YT3G (X, Y = A,C,G,T). Nucleic Acids Res (1985) 7.19
An alternative approach to deoxyoligonucleotides as hybridization probes by insertion of deoxyinosine at ambiguous codon positions. J Biol Chem (1985) 4.44
Base pairing involving deoxyinosine: implications for probe design. Nucleic Acids Res (1985) 4.41
Molecular cloning of the human cholecystokinin gene by use of a synthetic probe containing deoxyinosine. Proc Natl Acad Sci U S A (1985) 3.01
Synthesis and biophysical studies of short oligodeoxynucleotides with novel modifications: a possible approach to the problem of mixed base oligodeoxynucleotide synthesis. Nucleic Acids Res (1984) 3.00
Studies on the biochemical basis of spontaneous mutation. II. The incorporation of a base and its analogue into DNA by wild-type, mutator and antimutator DNA polymerases. J Mol Biol (1974) 2.79
Mismatches in DNA double strands: thermodynamic parameters and their correlation to repair efficiencies. Nucleic Acids Res (1986) 2.73
Isolation of a human anti-haemophilic factor IX cDNA clone using a unique 52-base synthetic oligonucleotide probe deduced from the amino acid sequence of bovine factor IX. Nucleic Acids Res (1983) 2.56
Error induction and correction by mutant and wild type T4 DNA polymerases. Kinetic error discrimination mechanisms. J Biol Chem (1979) 2.53
A high molecular weight DNA polymerase from Drosophila melanogaster embryos. Purification, structure, and partial characterization. J Biol Chem (1979) 2.23
Base pairing and mutagenesis: observation of a protonated base pair between 2-aminopurine and cytosine in an oligonucleotide by proton NMR. Proc Natl Acad Sci U S A (1986) 2.09
Quantitative studies of the avidity of naturally occurring substances for trace metals. III. Pteridines, riboflavin and purines. Biochem J (1953) 1.98
Comparison of nucleotide interactions in water, proteins, and vacuum: model for DNA polymerase fidelity. Proc Natl Acad Sci U S A (1986) 1.80
Synthesis and properties of O6-methyldeoxyguanylic acid and its copolymers with deoxycytidylic acid. Biochim Biophys Acta (1978) 1.74
Solid-phase synthesis of polynucleotides. VIII: A simplified synthesis of oligodeoxyribonucleotides. Cold Spring Harb Symp Quant Biol (1983) 1.70
Synthesis and properties of defined DNA oligomers containing base mispairs involving 2-aminopurine. Nucleic Acids Res (1986) 1.57
Synthesis and hybridization of dodecadeoxyribonucleotides containing a fluorescent pyridopyrimidine deoxynucleoside. Nucleic Acids Res (1985) 1.38
On the molecular basis of transition mutations: frequencies of forming 2-aminopurine.cytosine and adenine.cytosine base mispairs in vitro. Proc Natl Acad Sci U S A (1981) 1.22
On the molecular basis of transition mutations. Frequency of forming 2-aminopurine-cytosine base mispairs in the G X C----A X T mutational pathway by T4 DNA polymerase in vitro. J Biol Chem (1984) 1.06
Polynucleotide analogues. IX. Polyxanthylic acid. Biochim Biophys Acta (1966) 1.00
Properties of poly-xanthylic acid and its reactions with potentially complementary homopolynucleotides. Acta Biochim Pol (1969) 0.84
Investigations on the structures of xanthine-uracil and xanthine-adenine copolymers and their complexes with homopolynucleotides. Acta Biochim Pol (1970) 0.79
Hybridization of synthetic oligodeoxyribonucleotides to phi chi 174 DNA: the effect of single base pair mismatch. Nucleic Acids Res (1979) 14.12
The use of synthetic oligonucleotides as hybridization probes. II. Hybridization of oligonucleotides of mixed sequence to rabbit beta-globin DNA. Nucleic Acids Res (1981) 9.56
Expression in Escherichia coli of a chemically synthesized gene for the hormone somatostatin. Science (1977) 9.28
The importance of repairing stalled replication forks. Nature (2000) 7.93
Detection of sickle cell beta S-globin allele by hybridization with synthetic oligonucleotides. Proc Natl Acad Sci U S A (1983) 7.52
Use of synthetic oligonucleotides as hybridization probes: isolation of cloned cDNA sequences for human beta 2-microglobulin. Proc Natl Acad Sci U S A (1981) 7.24
Crystal structure analysis of a complete turn of B-DNA. Nature (1980) 7.18
Directed deletion of a yeast transfer RNA intervening sequence. Science (1980) 6.67
The Y-family of DNA polymerases. Mol Cell (2001) 6.49
Solid phase synthesis of polynucleotides. VI. Further studies on polystyrene copolymers for the solid support. Nucleic Acids Res (1982) 6.38
Structure of a B-DNA dodecamer: conformation and dynamics. Proc Natl Acad Sci U S A (1981) 6.38
Chemical synthesis of genes for human insulin. Proc Natl Acad Sci U S A (1978) 6.09
Fidelity mechanisms in DNA replication. Annu Rev Biochem (1991) 5.93
High-salt d(CpGpCpG), a left-handed Z' DNA double helix. Nature (1980) 5.46
Synthetic lac operator DNA is functional in vivo. Nature (1976) 5.36
A set of synthetic oligodeoxyribonucleotide primers for DNA sequencing in the plasmid vector pBR322. Gene (1981) 5.06
Chemical synthesis of restriction enzyme recognition sites useful for cloning. Science (1977) 4.81
Expression in Escherichia coli of chemically synthesized genes for human insulin. Proc Natl Acad Sci U S A (1979) 4.72
Solid-phase synthesis of polynucleotides. III. Synthesis of polynucleotides with defined sequences by the block coupling phosphotriester method. Nucleic Acids Res (1980) 4.69
Simplications in the synthesis of short oligonucleotide blocks. Nucleic Acids Res (1980) 4.64
Oligonucleotide-directed mutagenesis as a general and powerful method for studies of protein function. Proc Natl Acad Sci U S A (1982) 4.64
Synthesis and use of synthetic oligonucleotides. Annu Rev Biochem (1984) 4.53
alpha 1-antitrypsin deficiency detection by direct analysis of the mutation in the gene. Nature (1983) 4.38
UmuD'(2)C is an error-prone DNA polymerase, Escherichia coli pol V. Proc Natl Acad Sci U S A (1999) 4.24
Efficient correction of a mutation by use of chemically synthesized DNA. Proc Natl Acad Sci U S A (1978) 4.13
Improved triester approach for the synthesis of pentadecathymidylic acid. J Am Chem Soc (1975) 4.08
Comparison between DNA melting thermodynamics and DNA polymerase fidelity. Proc Natl Acad Sci U S A (1988) 4.07
Roles of E. coli DNA polymerases IV and V in lesion-targeted and untargeted SOS mutagenesis. Nature (2000) 3.95
Oligonucleotide directed mutagenesis of the human beta-globin gene: a general method for producing specific point mutations in cloned DNA. Nucleic Acids Res (1981) 3.87
Direct expression in Escherichia coli of a DNA sequence coding for human growth hormone. Nature (1979) 3.80
Structure, dynamics, and energetics of deoxyguanosine . thymidine wobble base pair formation in the self-complementary d(CGTGAATTCGCG) duplex in solution. Biochemistry (1982) 3.76
Extension of base mispairs by Taq DNA polymerase: implications for single nucleotide discrimination in PCR. Nucleic Acids Res (1992) 3.74
Gel fidelity assay measuring nucleotide misinsertion, exonucleolytic proofreading, and lesion bypass efficiencies. Methods Enzymol (1995) 3.65
Solid-phase synthesis of polynucleotides. IV. Usage of polystyrene resins for the synthesis of polydeoxyribonucleotides by the phosphostriester method. Nucleic Acids Res (1980) 3.59
DNA polymerase insertion fidelity. Gel assay for site-specific kinetics. J Biol Chem (1987) 3.59
Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue. Nature (1997) 3.55
Role of positive charge on the amino-terminal region of the signal peptide in protein secretion across the membrane. Proc Natl Acad Sci U S A (1982) 3.44
Ly-C: a third locus specifying alloantigens expressed only on thymocytes and lymphocytes. Transplantation (1971) 3.42
Nucleotide insertion kinetics opposite abasic lesions in DNA. J Biol Chem (1987) 3.41
Base mispair extension kinetics. Comparison of DNA polymerase alpha and reverse transcriptase. J Biol Chem (1990) 3.38
Genetic linkage relationships of loci specifying differentiation alloantigens in the mouse. Transplantation (1972) 3.34
Premelting and melting transitions in the d(CGCGAATTCGCG) self-complementary duplex in solution. Biochemistry (1982) 3.30
Solid-phase synthesis of polynucleotides. II. Synthesis of polythymidylic acids by the block coupling phosphotriester method. Nucleic Acids Res (1980) 3.20
The use of arylsulfonyltriazoles for the synthesis of oligonucleotides by the triester approach. J Am Chem Soc (1975) 3.16
Dissociation kinetics of 19 base paired oligonucleotide-DNA duplexes containing different single mismatched base pairs. Nucleic Acids Res (1987) 3.05
Extra adenosine stacks into the self-complementary d(CGCAGAATTCGCG) duplex in solution. Biochemistry (1982) 3.02
Chemical synthesis and sequence studies of deoxyribooligonucleotides which constitute the duplex sequence of the lactose operator of Escherichia coli. J Biol Chem (1975) 2.79
Studies on the biochemical basis of spontaneous mutation. II. The incorporation of a base and its analogue into DNA by wild-type, mutator and antimutator DNA polymerases. J Mol Biol (1974) 2.79
Crystal structure of a DNA Holliday junction. Nat Struct Biol (1999) 2.69
Effects of the complete removal of basic amino acid residues from the signal peptide on secretion of lipoprotein in Escherichia coli. J Biol Chem (1983) 2.66
Error induction and correction by mutant and wild type T4 DNA polymerases. Kinetic error discrimination mechanisms. J Biol Chem (1979) 2.53
The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways. Nature (2001) 2.46
Deoxyguanosine-deoxyadenosine pairing in the d(C-G-A-G-A-A-T-T-C-G-C-G) duplex: conformation and dynamics at and adjacent to the dG X dA mismatch site. Biochemistry (1984) 2.44
DNA conformation, dynamics, and interactions in solution. Science (1982) 2.30
Nearest neighbor influences on DNA polymerase insertion fidelity. J Biol Chem (1989) 2.29
Biochemical basis of SOS-induced mutagenesis in Escherichia coli: reconstitution of in vitro lesion bypass dependent on the UmuD'2C mutagenic complex and RecA protein. Proc Natl Acad Sci U S A (1998) 2.22
Solid phase synthesis of polynucleotides. VIII. Synthesis of mixed oligodeoxyribonucleotides by the phosphotriester solid phase method. Nucleic Acids Res (1983) 2.20
Solid-phase synthesis of polynucleotides: V. Synthesis of oligodeoxyribonucleotides by the phosphomonotriazolide method. Nucleic Acids Symp Ser (1980) 2.20
Isolation of a cDNA clone for the murine transplantation antigen H-2Kb. Proc Natl Acad Sci U S A (1982) 2.20
Base pairing and mutagenesis: observation of a protonated base pair between 2-aminopurine and cytosine in an oligonucleotide by proton NMR. Proc Natl Acad Sci U S A (1986) 2.09
Activity of the purified mutagenesis proteins UmuC, UmuD', and RecA in replicative bypass of an abasic DNA lesion by DNA polymerase III. Proc Natl Acad Sci U S A (1992) 2.03
The human papillomavirus type 16 E2 transcription factor binds with low cooperativity to two flanking sites and represses the E6 promoter through displacement of Sp1 and TFIID. J Virol (1994) 2.01
Deoxyadenosine-deoxycytidine pairing in the d(C-G-C-G-A-A-T-T-C-A-C-G) duplex: conformation and dynamics at and adjacent to the dA X dC mismatch site. Biochemistry (1984) 1.98
The use of synthetic oligodeoxyribonucleotides to produce specific deletions in the araBAD promoter of Escherichia coli B/r. Gene (1982) 1.98
Purification and characterization of an inducible Escherichia coli DNA polymerase capable of insertion and bypass at abasic lesions in DNA. J Biol Chem (1988) 1.97
Comparison of HIV-1 and avian myeloblastosis virus reverse transcriptase fidelity on RNA and DNA templates. J Biol Chem (1992) 1.96
DNA polymerase II is encoded by the DNA damage-inducible dinA gene of Escherichia coli. Proc Natl Acad Sci U S A (1990) 1.95
Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP. Nature (1997) 1.90
ATF-2 has intrinsic histone acetyltransferase activity which is modulated by phosphorylation. Nature (2000) 1.89
Spectroscopic and calorimetric characterizations of DNA duplexes containing 2-aminopurine. Biochemistry (1996) 1.88
Proofreading-defective DNA polymerase II increases adaptive mutation in Escherichia coli. Proc Natl Acad Sci U S A (1995) 1.85
Abasic translesion synthesis by DNA polymerase beta violates the "A-rule". Novel types of nucleotide incorporation by human DNA polymerase beta at an abasic lesion in different sequence contexts. J Biol Chem (1997) 1.83
Purification of insulin receptor with full binding activity. J Biol Chem (1983) 1.82
The abasic site as a challenge to DNA polymerase. A nuclear magnetic resonance study of G, C and T opposite a model abasic site. J Mol Biol (1990) 1.81
Comparison of nucleotide interactions in water, proteins, and vacuum: model for DNA polymerase fidelity. Proc Natl Acad Sci U S A (1986) 1.80
Direct detection of HIV-1 RNA from AIDS and ARC patient samples. DNA (1988) 1.79
Influence of neighboring bases on DNA polymerase insertion and proofreading fidelity. J Biol Chem (1985) 1.78
Structure of the TPR domain of p67phox in complex with Rac.GTP. Mol Cell (2000) 1.77
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Inhibition of human immunodeficiency virus by using an oligonucleoside methylphosphonate targeted to the tat-3 gene. J Virol (1988) 1.73
Crystal structure of a DinB family error-prone DNA polymerase from Sulfolobus solfataricus. Nat Struct Biol (2001) 1.72
Processive DNA synthesis by DNA polymerase II mediated by DNA polymerase III accessory proteins. J Biol Chem (1992) 1.72
Isolation of a cDNA clone for human X-linked 3-phosphoglycerate kinase by use of a mixture of synthetic oligodeoxyribonucleotides as a detection probe. Proc Natl Acad Sci U S A (1983) 1.71
Fidelity of Escherichia coli DNA polymerase III holoenzyme. The effects of beta, gamma complex processivity proteins and epsilon proofreading exonuclease on nucleotide misincorporation efficiencies. J Biol Chem (1997) 1.70
Dynamics of DNA duplexes containing internal G.T, G.A, A.C, and T.C pairs: hydrogen exchange at and adjacent to mismatch sites. Fed Proc (1984) 1.70
Solid-phase synthesis of polynucleotides. VIII: A simplified synthesis of oligodeoxyribonucleotides. Cold Spring Harb Symp Quant Biol (1983) 1.70
A phenotype for enigmatic DNA polymerase II: a pivotal role for pol II in replication restart in UV-irradiated Escherichia coli. Proc Natl Acad Sci U S A (1999) 1.69