Published in Adv Cancer Res on January 01, 1978
Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma. Am J Pathol (1993) 6.55
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Intratumor microvessel density as a prognostic factor in cancer. Am J Pathol (1995) 4.37
History of myeloid-derived suppressor cells. Nat Rev Cancer (2013) 3.14
Actinin-4, a novel actin-bundling protein associated with cell motility and cancer invasion. J Cell Biol (1998) 2.62
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Technical considerations for studying cancer metastasis in vivo. Clin Exp Metastasis (1997) 1.62
A potential role for interleukin-8 in the metastatic phenotype of breast carcinoma cells. Am J Pathol (2001) 1.51
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Enhanced expression of urokinase plasminogen activator and its receptor in pancreatic carcinoma. Br J Cancer (1997) 1.47
The extent of primary melanoma excision. A re-evaluation--how wide is wide? Ann Surg (1983) 1.45
Oligosaccharide modification by swainsonine treatment inhibits pulmonary colonization by B16-F10 murine melanoma cells. Proc Natl Acad Sci U S A (1986) 1.37
Eradication of spontaneous metastases and activation of alveolar macrophages by intravenous injection of liposomes containing muramyl dipeptide. Proc Natl Acad Sci U S A (1981) 1.34
Mucin production by human colonic carcinoma cells correlates with their metastatic potential in animal models of colon cancer metastasis. J Clin Invest (1991) 1.32
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Targeting cancer micrometastases with monoclonal antibodies: a binding-site barrier. Proc Natl Acad Sci U S A (1995) 1.27
Expression of human recombinant plasminogen activators enhances invasion and experimental metastasis of H-ras-transformed NIH 3T3 cells. Mol Cell Biol (1989) 1.21
Investigation of the biological effects of anti-cell adhesive synthetic peptides that inhibit experimental metastasis of B16-F10 murine melanoma cells. J Clin Invest (1988) 1.18
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Differential adhesion of tumor cells to capillary endothelial cells in vitro. Proc Natl Acad Sci U S A (1984) 1.13
Cellular heterogeneity in a tissue culture cell line derived from a human bladder carcinoma. Br J Cancer (1983) 1.10
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Interactions of human prostatic epithelial cells with bone marrow endothelium: binding and invasion. Br J Cancer (2001) 1.00
Metastatic variants are generated spontaneously at a high rate in mouse KHT tumor. Proc Natl Acad Sci U S A (1982) 0.99
Tumor promoter-induced membrane-bound protein kinase C regulates hematogenous metastasis. Proc Natl Acad Sci U S A (1988) 0.98
Malignancies of metastatic murine lymphosarcoma cell lines and clones correlate with decreased cell surface display of RNA tumor virus envelope glycoprotein gp70. Proc Natl Acad Sci U S A (1980) 0.98
New paradigm for vessel intravasation by tumor cells. Am J Pathol (2002) 0.98
Effect of piperine on the inhibition of lung metastasis induced B16F-10 melanoma cells in mice. Clin Exp Metastasis (2002) 0.98
Rejection of B16 melanoma induced by expression of a transfected major histocompatibility complex class I gene. Mol Cell Biol (1988) 0.97
Tobacco smoke tumor promoters, catechol and hydroquinone, induce oxidative regulation of protein kinase C and influence invasion and metastasis of lung carcinoma cells. Proc Natl Acad Sci U S A (1994) 0.95
Five human tumour cell lines derived from a primary squamous carcinoma of the tongue, two subsequent local recurrences and two nodal metastases. Br J Cancer (1981) 0.95
The ultrastructure of conjunctival melanocytic tumors. Trans Am Ophthalmol Soc (1984) 0.93
Isolation and preliminary characterisation of cDNA clones representing mRNAs associated with tumour progression and metastasis in colorectal cancer. Br J Cancer (1988) 0.91
Murine melanoma: a model for intracranial metastasis. Br J Cancer (1980) 0.89
Inhibitory effect of serum from rats administered with coffee on the proliferation and invasion of rat ascites hepatoma cells. Cytotechnology (1997) 0.87
Immunohistochemical method identifies lymphovascular invasion in a majority of oral squamous cell carcinomas and discriminates between blood and lymphatic vessel invasion. J Histochem Cytochem (2008) 0.87
Transcriptional analysis of the mts1 gene with specific reference to 5' flanking sequences. Proc Natl Acad Sci U S A (1992) 0.86
Properties of metastatic and nonmetastatic cloned subpopulations of an ultraviolet-light-induced murine fibrosarcoma of recent origin. Am J Pathol (1979) 0.84
Differential expression of a tropomyosin isoform in low- and high-metastatic Lewis lung carcinoma cells. Mol Cell Biol (1988) 0.84
Inhibitory effect of ascorbic Acid on the proliferation and invasion of hepatoma cells in culture. Cytotechnology (2005) 0.83
Suppression of pulmonary tumour metastasis in mice by recombinant human interleukin-2: role of asialo GM1-positive cells. Immunology (1987) 0.83
Inostamycin, an inhibitor of cytidine 5'-diphosphate 1,2-diacyl-sn-glycerol (CDP-DG): inositol transferase, suppresses invasion ability by reducing productions of matrix metalloproteinase-2 and -9 and cell motility in HSC-4 tongue carcinoma cell line. Clin Exp Metastasis (2000) 0.81
Culturing of human hepatocellular carcinoma. A simple and reproducible method. Am J Pathol (1985) 0.81
Host proteolytic activity is necessary for infectious bursal disease virus capsid protein assembly. J Biol Chem (2012) 0.80
Deoxyribonuclease treatment prevents blood-borne liver metastasis of cutaneously transplanted tumour cells in mice. Br J Cancer (1993) 0.79
Invasion and metastasis. Can Med Assoc J (1983) 0.79
Thymosin beta15 expression in tumor cell lines with varying metastatic potential. Clin Exp Metastasis (1998) 0.79
Clonal variation in the arrest, survival and growth of RIF-1 mouse sarcoma cells in the lungs of C3H mice. Br J Cancer (1983) 0.79
Differential distributions of CSE1L/CAS and E-cadherin in the polarized and non-polarized epithelial glands of neoplastic colorectal epithelium. J Mol Histol (2010) 0.78
Some aspects of the metastatic process. J Clin Pathol (1982) 0.78
Distribution of anionic surface sites on human melanocytes and human melanoma cells in culture. Arch Dermatol Res (1983) 0.78
Cytotoxicity of unstimulated and thrombin-activated platelets to human tumour cells. Immunology (1993) 0.78
Metastasis of murine mammary tumour lines from the mammary gland and ectopic sites. Br J Cancer (1984) 0.78
Minimal residual disease in breast cancer: an overview of circulating and disseminated tumour cells. Clin Exp Metastasis (2016) 0.77
CARP is a potential tumor suppressor in gastric carcinoma and a single-nucleotide polymorphism in CARP gene might increase the risk of gastric carcinoma. PLoS One (2014) 0.76
Swainsonine: a new antineoplastic immunomodulator. J Natl Med Assoc (1989) 0.75
The evolving concept of liver cancer stem cells. Mol Cancer (2017) 0.75
Variant selection and blood-borne "clonogenic" tumour cells in metastasis of FSA cell clones. Br J Cancer (1983) 0.75
Morphological characterization of cellular and extracellular components of 7,12 dimethylbenz[a]anthracene induced melanoma tumours. Br J Exp Pathol (1987) 0.75
Differing lectin-binding patterns of malignant melanoma and nevocellular and Spitz nevi. Arch Dermatol Res (1987) 0.75
Immunohistological detection of human malignant melanoma using monoclonal antibody to a melanoma-associated antigen. Arch Dermatol Res (1985) 0.75
Elevated glycosyltransferase activities in infected or traumatized hosts: nonspecific response to inflammation. Infect Immun (1980) 0.75
Biology of human cutaneous melanoma. Cancers (Basel) (2010) 0.75
Collagenase derived from human fibrosarcoma is responsible for degradation of basement membranes. Int J Exp Pathol (1991) 0.75
Chemical carcinogens: a review of the science and its associated principles. U.S. Interagency Staff Group on Carcinogens. Environ Health Perspect (1986) 0.75
Correlation between differentiation and lung colonization by retinoic acid-treated F9 cells as revealed by the expression pattern of extracellular matrix and cell surface antigens. Am J Pathol (1988) 0.75
Down-regulation of focal adhesion kinase, pp125FAK, in endothelial cell retraction during tumor cell invasion. Clin Exp Metastasis (1998) 0.75
Metastasis results from preexisting variant cells within a malignant tumor. Science (1977) 6.47
The pathogenesis of cancer metastasis. Nature (1980) 5.74
Selection of successive tumour lines for metastasis. Nat New Biol (1973) 5.03
Metastasis: quantitative analysis of distribution and fate of tumor emboli labeled with 125 I-5-iodo-2'-deoxyuridine. J Natl Cancer Inst (1970) 4.88
Biological diversity in metastatic neoplasms: origins and implications. Science (1982) 3.95
A line of non-tumorigenic mouse melanocytes, syngeneic with the B16 melanoma and requiring a tumour promoter for growth. Int J Cancer (1987) 3.80
Biological behavior of malignant melanoma cells correlated to their survival in vivo. Cancer Res (1975) 3.59
Tumor heterogeneity and the biology of cancer invasion and metastasis. Cancer Res (1978) 3.54
Simulation technology for health care professional skills training and assessment. JAMA (1999) 3.49
Correlation of patterns of anchorage-independent growth with in vivo behavior of cells from a murine fibrosarcoma. Proc Natl Acad Sci U S A (1980) 3.38
Orthotopic models are necessary to predict therapy of transplantable tumors in mice. Cancer Metastasis Rev (1999) 2.83
Blockade of NF-kappaB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis. Oncogene (2001) 2.71
In vivo selection and characterization of metastatic variants from human pancreatic adenocarcinoma by using orthotopic implantation in nude mice. Neoplasia (1999) 2.71
Influence of organ environment on the growth, selection, and metastasis of human colon carcinoma cells in nude mice. Cancer Res (1988) 2.67
Selection of highly metastatic variants of different human prostatic carcinomas using orthotopic implantation in nude mice. Clin Cancer Res (1996) 2.59
The relationship of embolic homogeneity, number, size and viability to the incidence of experimental metastasis. Eur J Cancer (1973) 2.54
Early onset of breast cancer in a group of British black women. Br J Cancer (2008) 2.47
Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma. Cancer Res (2000) 2.43
Rationale and methods for the use of nude mice to study the biology and therapy of human cancer metastasis. Cancer Metastasis Rev (1986) 2.42
The selection and characterization of an invasive variant of the B16 melanoma. Am J Pathol (1979) 2.42
In vitro selection of murine B16 melanoma variants with enhanced tissue-invasive properties. Cancer Res (1980) 2.40
Interferon-alpha-mediated down-regulation of angiogenesis-related genes and therapy of bladder cancer are dependent on optimization of biological dose and schedule. Clin Cancer Res (1999) 2.39
Staining for enzymatic activity after gel electrophoresis, I. Anal Biochem (1992) 2.39
Elevated expression of phosphatidylserine in the outer membrane leaflet of human tumor cells and recognition by activated human blood monocytes. Cancer Res (1991) 2.37
In vivo selection of highly metastatic cells from surgical specimens of different primary human colon carcinomas implanted into nude mice. Cancer Res (1988) 2.36
Expression of angiogenesis-related genes and progression of human ovarian carcinomas in nude mice. J Natl Cancer Inst (1998) 2.36
Growth and metastasis of tumor cells isolated from a human renal cell carcinoma implanted into different organs of nude mice. Cancer Res (1986) 2.30
Expression of interleukin 8 correlates with the metastatic potential of human melanoma cells in nude mice. Cancer Res (1994) 2.28
Metastatic heterogeneity of cells from an ultraviolet light-induced murine fibrosarcoma of recent origin. Cancer Res (1978) 2.28
Macrophage-derived metalloelastase is responsible for the generation of angiostatin in Lewis lung carcinoma. Cell (1997) 2.16
Metastatic behavior of human tumor cell lines grown in the nude mouse. Cancer Res (1984) 2.13
Organ selectivity for implantation survival and growth of B16 melanoma variant tumor lines. J Natl Cancer Inst (1976) 2.09
A human melanoma line heterogeneous with respect to metastatic capacity in athymic nude mice. J Natl Cancer Inst (1984) 2.08
BEME Guide No. 1: Best Evidence Medical Education. Med Teach (1999) 2.01
Influence of organ environment on extracellular matrix degradative activity and metastasis of human colon carcinoma cells. J Natl Cancer Inst (1990) 2.00
Metastatic model for human prostate cancer using orthotopic implantation in nude mice. J Natl Cancer Inst (1992) 2.00
Specificity of arrest, survival, and growth of selected metastatic variant cell lines. Cancer Res (1978) 1.99
Blockade of nuclear factor-kappaB signaling inhibits angiogenesis and tumorigenicity of human ovarian cancer cells by suppressing expression of vascular endothelial growth factor and interleukin 8. Cancer Res (2000) 1.98
Role of organ selectivity in the determination of metastatic patterns of B16 melanoma. Cancer Res (1980) 1.97
Relative malignant potential of human breast carcinoma cell lines established from pleural effusions and a brain metastasis. Invasion Metastasis (1991) 1.95
Mekk3 is essential for early embryonic cardiovascular development. Nat Genet (2000) 1.95
A simple quantitative assay for studying the invasive potential of high and low human metastatic variants. Cancer Lett (1987) 1.94
E-cadherin expression in colorectal cancer. An immunocytochemical and in situ hybridization study. Am J Pathol (1993) 1.89
Interferons alpha and beta down-regulate the expression of basic fibroblast growth factor in human carcinomas. Proc Natl Acad Sci U S A (1995) 1.87
Interactions among clonal subpopulations affect stability of the metastatic phenotype in polyclonal populations of B16 melanoma cells. Proc Natl Acad Sci U S A (1981) 1.87
Isolation and characterization of metastatic variants from human transitional cell carcinoma passaged by orthotopic implantation in athymic nude mice. J Urol (1995) 1.82
Expression of interleukin-8 correlates with vascularity in human gastric carcinomas. Am J Pathol (1998) 1.75
Angiogenesis and metastasis. Eur J Cancer (1996) 1.72
Level and function of epidermal growth factor receptor predict the metastatic potential of human colon carcinoma cells. Clin Cancer Res (1995) 1.71
Inhibition of murine melanoma experimental metastasis by recombinant desulfatohirudin, a highly specific thrombin inhibitor. Cancer Res (1991) 1.70
Multiple ways of silencing E-cadherin gene expression in lobular carcinoma of the breast. Int J Cancer (2001) 1.64
The effect of human recombinant macrophage colony-stimulating factor (CSF-1) on the murine mononuclear phagocyte system in vivo. J Immunol (1988) 1.63
In vivo selection of human renal cell carcinoma cells with high metastatic potential in nude mice. Clin Exp Metastasis (1989) 1.62
Development of a quantitative method to analyse tumour cell invasion in organotypic culture. J Pathol (2005) 1.61
Inhibitors of nitric oxide synthase selectively reduce flow in tumor-associated neovasculature. Br J Pharmacol (1992) 1.61
Angiogenesis and breast cancer metastasis. Lancet (1995) 1.55
Destruction of bystander cells by tumor cells transfected with inducible nitric oxide (NO) synthase gene. J Natl Cancer Inst (1997) 1.55
Expression of interleukin-8 correlates with angiogenesis, tumorigenicity, and metastasis of human prostate cancer cells implanted orthotopically in nude mice. Neoplasia (2001) 1.52
Evidence for the clonal origin of spontaneous metastases. Science (1982) 1.52
Role of tumor necrosis factor in flavone acetic acid-induced tumor vasculature shutdown. Cancer Res (1990) 1.51
Use of tissue-specific expression of the herpes simplex virus thymidine kinase gene to inhibit growth of established murine melanomas following direct intratumoral injection of DNA. Cancer Res (1993) 1.50
Orthotopic and ectopic organ environments differentially influence the sensitivity of murine colon carcinoma cells to doxorubicin and 5-fluorouracil. Int J Cancer (1992) 1.50
Role of natural killer cells in the destruction of circulating tumor emboli. J Natl Cancer Inst (1980) 1.49
A rapid, novel method for the solid-phase derivatization of IgG antibodies for immune-affinity chromatography. J Immunol Methods (1978) 1.49
Nuclear factor-kappaB activity correlates with growth, angiogenesis, and metastasis of human melanoma cells in nude mice. Clin Cancer Res (2000) 1.48
Acidic pH-induced elevation in interleukin 8 expression by human ovarian carcinoma cells. Cancer Res (2000) 1.47
Metastatic behavior of tumor cells isolated from primary and metastatic human colorectal carcinomas implanted into different sites in nude mice. Cancer Res (1986) 1.47
Constitutive and inducible interleukin 8 expression by hypoxia and acidosis renders human pancreatic cancer cells more tumorigenic and metastatic. Clin Cancer Res (1999) 1.45
Increasing metastatic potential is associated with increasing genetic instability of clones isolated from murine neoplasms. Proc Natl Acad Sci U S A (1981) 1.44
Characterization in vivo and in vitro of tumor cells selected for resistance to syngeneic lymphocyte-mediated cytotoxicity. Cancer Res (1976) 1.44
Tyrosine phosphorylation of mitogen-activated protein kinases is necessary for activation of murine macrophages by natural and synthetic bacterial products. J Exp Med (1993) 1.44
Macrophages and metastasis--a biological approach to cancer therapy. Cancer Res (1985) 1.43
Specific chromosomal defects associated with metastatic potential in K-1735 melanoma clones. Involvement of chromosomes 4 and 14. Cancer Genet Cytogenet (1991) 1.41
Involvement of macrophages in the eradication of established metastases following intravenous injection of liposomes containing macrophage activators. Cancer Res (1982) 1.40
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Experimental nude mouse model of human colorectal cancer liver metastases. J Natl Cancer Inst (1986) 1.38
Organ-specific modulation of steady-state mdr gene expression and drug resistance in murine colon cancer cells. J Natl Cancer Inst (1994) 1.37
Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells. J Exp Med (1995) 1.37
Demonstration of multiple phenotypic diversity in a murine melanoma of recent origin. J Natl Cancer Inst (1981) 1.37
Cell uptake, distribution and response to aluminium chloro sulphonated phthalocyanine, a potential anti-tumour photosensitizer. Br J Cancer (1986) 1.36
Expression of vascular endothelial growth factor is necessary but not sufficient for production and growth of brain metastasis. Cancer Res (2000) 1.36
Integrin alpha5beta1-mediated adenovirus infection is enhanced by the integrin-activating antibody TS2/16. J Virol (1997) 1.34
Eradication of spontaneous metastases and activation of alveolar macrophages by intravenous injection of liposomes containing muramyl dipeptide. Proc Natl Acad Sci U S A (1981) 1.34
Evidence that intravenously derived murine pulmonary melanoma metastases can originate from the expansion of a single tumor cell. Cancer Res (1986) 1.33
Relationship of host immune status to tumor cell arrest, distribution, and survival in experimental metastasis. Cancer (1977) 1.33
Interleukin 8: an autocrine growth factor for human ovarian cancer. Oncol Res (2000) 1.33
Correlation of growth capacity of human tumor cells in hard agarose with their in vivo proliferative capacity at specific metastatic sites. J Natl Cancer Inst (1989) 1.32
Analysis of the fate of systemically administered liposomes and implications for their use in drug delivery. Cancer Res (1982) 1.32
Differential permeability of the blood-brain barrier in experimental brain metastases produced by human neoplasms implanted into nude mice. Am J Pathol (1992) 1.31
Inhibition of pulmonary metastasis by intravenous injection of specifically activated macrophages. Cancer Res (1974) 1.30
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Colocalization of kindlin-1, kindlin-2, and migfilin at keratinocyte focal adhesion and relevance to the pathophysiology of Kindler syndrome. J Invest Dermatol (2008) 1.29
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