Published in J Cell Biol on March 23, 1998
The integrin-actin connection, an eternal love affair. EMBO J (2003) 2.26
Proteomic analysis of exosomes secreted by human mesothelioma cells. Am J Pathol (2004) 2.13
Mutations in Mlph, encoding a member of the Rab effector family, cause the melanosome transport defects observed in leaden mice. Proc Natl Acad Sci U S A (2001) 2.00
Mice deficient in alpha-actinin-4 have severe glomerular disease. J Clin Invest (2003) 1.69
Quantitative proteomic analysis of single pancreatic islets. Proc Natl Acad Sci U S A (2009) 1.62
Alpha-actinin-4-mediated FSGS: an inherited kidney disease caused by an aggregated and rapidly degraded cytoskeletal protein. PLoS Biol (2004) 1.58
Integrin-dependent force transmission to the extracellular matrix by α-actinin triggers adhesion maturation. Proc Natl Acad Sci U S A (2013) 1.44
Interaction of G-protein βγ complex with chromatin modulates GPCR-dependent gene regulation. PLoS One (2013) 1.43
Focal adhesion size uniquely predicts cell migration. FASEB J (2012) 1.40
CART: an Hrs/actinin-4/BERP/myosin V protein complex required for efficient receptor recycling. Mol Biol Cell (2005) 1.39
A retrovirus-based protein complementation assay screen reveals functional AKT1-binding partners. Proc Natl Acad Sci U S A (2006) 1.36
Isoform-specific contributions of alpha-actinin to glioma cell mechanobiology. PLoS One (2009) 1.34
Motility-related proteins as markers for head and neck squamous cell cancer. Laryngoscope (2001) 1.28
Differentiation- and stress-dependent nuclear cytoplasmic redistribution of myopodin, a novel actin-bundling protein. J Cell Biol (2001) 1.25
Dynamic (re)organization of the podocyte actin cytoskeleton in the nephrotic syndrome. Pediatr Nephrol (2003) 1.25
The role of palladin in actin organization and cell motility. Eur J Cell Biol (2008) 1.22
Palladin contributes to invasive motility in human breast cancer cells. Oncogene (2008) 1.17
Molecular processes during fat cell development revealed by gene expression profiling and functional annotation. Genome Biol (2005) 1.16
α-actinin-4 is essential for maintaining the spreading, motility and contractility of fibroblasts. PLoS One (2010) 1.11
Quantitative proteomics investigation of pancreatic intraepithelial neoplasia. Electrophoresis (2009) 1.08
Cell Adhesion and Transcriptional Activity - Defining the Role of the Novel Protooncogene LPP. Transl Oncol (2009) 1.05
Glomerular diseases: genetic causes and future therapeutics. Nat Rev Nephrol (2010) 1.03
Cytoplasmic Ig-domain proteins: cytoskeletal regulators with a role in human disease. Cell Motil Cytoskeleton (2009) 1.02
Motility-related actinin alpha-4 is associated with advanced and metastatic ovarian carcinoma. Lab Invest (2008) 1.01
The actin-binding protein, actinin alpha 4 (ACTN4), is a nuclear receptor coactivator that promotes proliferation of MCF-7 breast cancer cells. J Biol Chem (2010) 1.00
Actin stress fibre subtypes in mesenchymal-migrating cells. Open Biol (2013) 0.99
UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE) binds to alpha-actinin 1: novel pathways in skeletal muscle? PLoS One (2008) 0.98
MTBP suppresses cell migration and filopodia formation by inhibiting ACTN4. Oncogene (2012) 0.94
ICAM-2 expression mediates a membrane-actin link, confers a nonmetastatic phenotype and reflects favorable tumor stage or histology in neuroblastoma. PLoS One (2008) 0.94
Identification of a novel LXXLL motif in α-actinin 4-spliced isoform that is critical for its interaction with estrogen receptor α and co-activators. J Biol Chem (2012) 0.93
Ultrastructural localization of actin and actin-binding proteins in the nucleus. Histochem Cell Biol (2008) 0.93
Intermediate filament protein synemin contributes to the migratory properties of astrocytoma cells by influencing the dynamics of the actin cytoskeleton. FASEB J (2008) 0.91
Cytoskeletal signaling by way of alpha-actinin-1 mediates ERK1/2 activation by repetitive deformation in human Caco2 intestinal epithelial cells. Am J Surg (2007) 0.90
Identification of BERP (brain-expressed RING finger protein) as a p53 target gene that modulates seizure susceptibility through interacting with GABA(A) receptors. Proc Natl Acad Sci U S A (2010) 0.89
Serial analysis of gene expression reveals differential expression between endometriosis and normal endometrium. Possible roles for AXL and SHC1 in the pathogenesis of endometriosis. Reprod Biol Endocrinol (2008) 0.89
Genetics of focal segmental glomerulosclerosis. Pediatr Nephrol (2007) 0.89
The role of alpha-actinin-4 in human kidney disease. Cell Biosci (2015) 0.89
The biological role of actinin-4 (ACTN4) in malignant phenotypes of cancer. Cell Biosci (2015) 0.89
Downregulation of thrombomodulin, a novel target of Snail, induces tumorigenesis through epithelial-mesenchymal transition. Mol Cell Biol (2010) 0.88
Alpha-actinin 4 and BAT1 interaction with the cytochrome c promoter upon skeletal muscle differentiation. Curr Genet (2005) 0.88
Expression of nephrin, podocin, alpha-actinin, and WT1 in children with nephrotic syndrome. Pediatr Nephrol (2003) 0.88
Altered plasma apolipoprotein modifications in patients with pancreatic cancer: protein characterization and multi-institutional validation. PLoS One (2012) 0.87
Proteome analysis of multidrug-resistant, breast cancer-derived microparticles. J Extracell Vesicles (2014) 0.87
Familial focal segmental glomerulosclerosis (FSGS)-linked α-actinin 4 (ACTN4) protein mutants lose ability to activate transcription by nuclear hormone receptors. J Biol Chem (2012) 0.87
Comparative analysis of tumorbiology and CD133 positivity in primary and recurrent pancreatic ductal adenocarcinoma. Clin Exp Metastasis (2009) 0.87
Actinin-4 in keratinocytes regulates motility via an effect on lamellipodia stability and matrix adhesions. FASEB J (2012) 0.86
Tumor antigens for cancer immunotherapy: therapeutic potential of xenogeneic DNA vaccines. J Transl Med (2004) 0.86
Plasma biomarker for detection of early stage pancreatic cancer and risk factors for pancreatic malignancy using antibodies for apolipoprotein-AII isoforms. Sci Rep (2015) 0.86
ACTN4 copy number increase as a predictive biomarker for chemoradiotherapy of locally advanced pancreatic cancer. Br J Cancer (2015) 0.85
Copy number increase of ACTN4 is a prognostic indicator in salivary gland carcinoma. Cancer Med (2014) 0.85
Proteomic-based biosignatures in breast cancer classification and prediction of therapeutic response. Int J Proteomics (2011) 0.85
Cell mechanosensitivity: mechanical properties and interaction with gravitational field. Biomed Res Int (2012) 0.84
Proteomic analysis reveals novel binding partners of metabotropic glutamate receptor 1. J Neurochem (2009) 0.84
Nucleocytoplasmic shuttling of cytoskeletal proteins: molecular mechanism and biological significance. Int J Cell Biol (2011) 0.84
α-Actinin-4 is required for amoeboid-type invasiveness of melanoma cells. J Biol Chem (2014) 0.84
The actinin family of actin cross-linking proteins - a genetic perspective. Cell Biosci (2015) 0.84
Focal Contact and Hemidesmosomal Proteins in Keratinocyte Migration and Wound Repair. Adv Wound Care (New Rochelle) (2014) 0.83
α-actinin1 and 4 tyrosine phosphorylation is critical for stress fiber establishment, maintenance and focal adhesion maturation. Exp Cell Res (2013) 0.83
The parafibromin tumor suppressor protein interacts with actin-binding proteins actinin-2 and actinin-3. Mol Cancer (2008) 0.82
Small leucine zipper protein (sLZIP) negatively regulates skeletal muscle differentiation via interaction with α-actinin-4. J Biol Chem (2013) 0.82
Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development. PLoS Genet (2015) 0.82
PDZ and LIM domain protein 1(PDLIM1)/CLP36 promotes breast cancer cell migration, invasion and metastasis through interaction with α-actinin. Oncogene (2014) 0.82
α-Actinin 4 potentiates nuclear factor κ-light-chain-enhancer of activated B-cell (NF-κB) activity in podocytes independent of its cytoplasmic actin binding function. J Biol Chem (2014) 0.81
The carboxyl tail of alpha-actinin-4 regulates its susceptibility to m-calpain and thus functions in cell migration and spreading. Int J Biochem Cell Biol (2013) 0.81
Concomitant inhibition of HSP90, its mitochondrial localized homologue TRAP1 and HSP27 by green tea in pancreatic cancer HPAF-II cells. Proteomics (2011) 0.81
Alpha-actinin-4 and CLP36 protein deficiencies contribute to podocyte defects in multiple human glomerulopathies. J Biol Chem (2011) 0.81
Structural characterization of the interactions between palladin and α-actinin. J Mol Biol (2011) 0.81
Podocyte Injury Associated with Mutant α-Actinin-4. J Signal Transduct (2011) 0.80
Adhesion protein networks reveal functions proximal and distal to cell-matrix contacts. Curr Opin Cell Biol (2016) 0.80
ACTN4 and the pathways associated with cell motility and adhesion contribute to the process of lung cancer metastasis to the brain. BMC Cancer (2015) 0.80
Phylogenetic analysis of gene structure and alternative splicing in alpha-actinins. Mol Biol Evol (2009) 0.80
An image-based multi-label human protein subcellular localization predictor (iLocator) reveals protein mislocalizations in cancer tissues. Bioinformatics (2013) 0.80
HAMLET binding to α-actinin facilitates tumor cell detachment. PLoS One (2011) 0.80
Separation and identification of HSP-associated protein complexes from pancreatic cancer cell lines using 2D CN/SDS-PAGE coupled with mass spectrometry. J Biomed Biotechnol (2011) 0.80
Distraction-induced intestinal growth: the role of mechanotransduction mechanisms in a mouse model of short bowel syndrome. Tissue Eng Part A (2013) 0.80
Inhibition of breast cancer invasion by TIS21(/BTG2/Pc3)-Akt1-Sp1-Nox4 pathway targeting actin nucleators, mDia genes. Oncogene (2015) 0.79
PDLIM1 inhibits NF-κB-mediated inflammatory signaling by sequestering the p65 subunit of NF-κB in the cytoplasm. Sci Rep (2015) 0.79
Relevance of the ACTN4 gene in African-Americans with non-diabetic end-stage renal disease. Am J Nephrol (2012) 0.79
Actin-binding protein alpha-actinin 4 (ACTN4) is a transcriptional co-activator of RelA/p65 sub-unit of NF-kB. Oncotarget (2013) 0.79
Alpha-actinin 4 and tumorigenesis of breast cancer. Vitam Horm (2013) 0.78
The role of the actin cytoskeleton in regulating Drosophila behavior. Rev Neurosci (2013) 0.78
Structure and functional characteristics of rat's left ventricle cardiomyocytes under antiorthostatic suspension of various duration and subsequent reloading. J Biomed Biotechnol (2012) 0.78
Identification of dynamic changes in proteins associated with the cellular cytoskeleton after exposure to okadaic acid. Mar Drugs (2013) 0.78
Dynamic regulation of endothelial NOS mediated by competitive interaction with alpha-actinin-4 and calmodulin. FASEB J (2008) 0.78
Cadherin selectivity filter regulates endothelial sieving properties. Nat Commun (2012) 0.78
α-Actinin-4 enhances colorectal cancer cell invasion by suppressing focal adhesion maturation. PLoS One (2015) 0.77
Efficacy of adjuvant chemotherapy for non-small cell lung cancer assessed by metastatic potential associated with ACTN4. Oncotarget (2016) 0.77
MTBP inhibits migration and metastasis of hepatocellular carcinoma. Clin Exp Metastasis (2015) 0.77
α-Actinin-4 induces the epithelial-to-mesenchymal transition and tumorigenesis via regulation of Snail expression and β-catenin stabilization in cervical cancer. Oncogene (2016) 0.77
1H, 13C and 15N resonance assignments of the third spectrin repeat of alpha-actinin-4. J Biomol NMR (2004) 0.76
Label-free LC-MSe in tissue and serum reveals protein networks underlying differences between benign and malignant serous ovarian tumors. PLoS One (2014) 0.76
Identification of CLP36 as a tumor antigen that induces an antibody response in pancreatic cancer. Cancer Res Treat (2005) 0.76
Molecular characterization and clinical course of MLL-ACTN4 rearrangement in therapy-related hematologic malignancies. Haematologica (2014) 0.76
Alpha actinin-1 regulates cell-matrix adhesion organization in keratinocytes: consequences for skin cell motility. J Invest Dermatol (2014) 0.76
Regulation of Cancer Cell Behavior by the Small GTPase Rab13. J Biol Chem (2016) 0.76
Curcumin modulates chronic myelogenous leukemia exosomes composition and affects angiogenic phenotype via exosomal miR-21. Oncotarget (2016) 0.75
Rapamycin regulates autophagy and cell adhesion in induced pluripotent stem cells. Stem Cell Res Ther (2016) 0.75
Poly-L-ornithine enhances migration of neural stem/progenitor cells via promoting α-Actinin 4 binding to actin filaments. Sci Rep (2016) 0.75
An Omics Perspective on Molecular Biomarkers for Diagnosis, Prognosis, and Therapeutics of Cholangiocarcinoma. Int J Genomics (2015) 0.75
The actinin family proteins: biological function and clinical implications. Cell Biosci (2015) 0.75
Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci U S A (1979) 365.71
Efficient isolation of genes by using antibody probes. Proc Natl Acad Sci U S A (1983) 34.00
Cell migration: a physically integrated molecular process. Cell (1996) 23.49
In vitro cultivation of human tumors: establishment of cell lines derived from a series of solid tumors. J Natl Cancer Inst (1973) 11.26
Alpha-actinin: immunofluorescent localization of a muscle structural protein in nonmuscle cells. Cell (1975) 6.93
Integrin function: molecular hierarchies of cytoskeletal and signaling molecules. J Cell Biol (1995) 6.74
On the crawling of animal cells. Science (1993) 6.39
An interaction between alpha-actinin and the beta 1 integrin subunit in vitro. J Cell Biol (1990) 5.66
Interaction of alpha-actinin with the cadherin/catenin cell-cell adhesion complex via alpha-catenin. J Cell Biol (1995) 3.86
Identification of novel graded polarity actin filament bundles in locomoting heart fibroblasts: implications for the generation of motile force. J Cell Biol (1997) 3.25
Nuclear localization signals (NLS). Crit Rev Eukaryot Gene Expr (1993) 3.05
The biology of cancer invasion and metastasis. Adv Cancer Res (1978) 2.94
Cell-to-substratum contacts in living cells: a direct correlation between interference-reflexion and indirect-immunofluorescence microscopy using antibodies against actin and alpha-actinin. J Cell Sci (1979) 2.93
Modular organization of actin crosslinking proteins. Trends Biochem Sci (1991) 2.69
Cytochalasin D inhibits actin polymerization and induces depolymerization of actin filaments formed during platelet shape change. Nature (1981) 2.63
Requirement of phosphatidylinositol 4,5-bisphosphate for alpha-actinin function. Nature (1992) 2.62
Molecular aspects of tumor cell invasion and metastasis. Cancer (1993) 2.24
The AMeX method. A simplified technique of tissue processing and paraffin embedding with improved preservation of antigens for immunostaining. Am J Pathol (1986) 2.19
Mapping of the alpha-actinin binding site within the beta 1 integrin cytoplasmic domain. J Biol Chem (1993) 1.95
Molecular and cellular features of esophageal cancer cells. J Cancer Res Clin Oncol (1993) 1.95
Thymosin beta 15: a novel regulator of tumor cell motility upregulated in metastatic prostate cancer. Nat Med (1996) 1.94
Cloning and characterization of two human skeletal muscle alpha-actinin genes located on chromosomes 1 and 11. J Biol Chem (1992) 1.91
Hepatocyte growth factor-induced scatter of Madin-Darby canine kidney cells requires phosphatidylinositol 3-kinase. J Biol Chem (1995) 1.82
Estradiol induced proteins in the MCF7 human breast cancer cell line. Biochem Biophys Res Commun (1979) 1.76
Cancer metastasis: tumor cell and host organ properties important in metastasis to specific secondary sites. Biochim Biophys Acta (1988) 1.75
Suppression of tumorigenicity in simian virus 40-transformed 3T3 cells transfected with alpha-actinin cDNA. Proc Natl Acad Sci U S A (1993) 1.69
The cellular basis of site-specific tumor metastasis. N Engl J Med (1990) 1.60
Fourier analysis of cell motility: correlation of motility with metastatic potential. Proc Natl Acad Sci U S A (1989) 1.55
Actin-membrane interaction in focal adhesions. Cell Differ Dev (1990) 1.47
Analysis of the actin-binding domain of alpha-actinin by mutagenesis and demonstration that dystrophin contains a functionally homologous domain. J Cell Biol (1992) 1.43
The fibroblast growth factor family: structural and biological properties. Prog Growth Factor Res (1989) 1.42
Activation of phosphatidylinositol 3-kinase by epidermal growth factor, basic fibroblast growth factor, and nerve growth factor in PC12 pheochromocytoma cells. Proc Natl Acad Sci U S A (1992) 1.31
Dominant negative inhibition of the association between beta-catenin and c-erbB-2 by N-terminally deleted beta-catenin suppresses the invasion and metastasis of cancer cells. Oncogene (1996) 1.30
Modulation of alpha-actinin levels affects cell motility and confers tumorigenicity on 3T3 cells. J Cell Sci (1994) 1.26
Identification of a phosphatidylinositol 4,5-bisphosphate-binding site in chicken skeletal muscle alpha-actinin. J Biol Chem (1996) 1.24
The Ca(2+)-binding domains in non-muscle type alpha-actinin: biochemical and genetic analysis. J Cell Biol (1993) 1.22
The identification and characterisation of an actin-binding site in alpha-actinin by mutagenesis. FEBS Lett (1992) 1.22
The isolation and long-term culture of normal human endometrial epithelium and stroma. Expression of mRNAs for angiogenic polypeptides basally and on oestrogen and progesterone challenges. J Cell Sci (1995) 1.17
Estrogens and growth factors induce the mRNA of the 52K-pro-cathepsin-D secreted by breast cancer cells. Nucleic Acids Res (1988) 1.15
Cloning and chromosomal localization of the human cytoskeletal alpha-actinin gene reveals linkage to the beta-spectrin gene. Am J Hum Genet (1990) 1.13
Mbh 1: a novel gelsolin/severin-related protein which binds actin in vitro and exhibits nuclear localization in vivo. EMBO J (1991) 1.11
The cDNA sequence of a human placental alpha-actinin. Nucleic Acids Res (1989) 1.06
Giant cell carcinomas of the lung producing colony-stimulating factor in vitro and in vivo. Jpn J Cancer Res (1985) 0.96
Monoclonal antibody reactive with the sialyl-sugar residue of a high molecular weight glycoprotein in sera of cancer patients. Gan (1984) 0.87
In vitro motility of cells from human epidermoid carcinomas. A study by phase-contrast and reflection-contrast cinematography. Int J Cancer (1981) 0.86
Wortmannin inhibits serum-induced activation of phosphoinositide 3-kinase and proliferation of CHRF-288 cells. Biochem Biophys Res Commun (1994) 0.85
Molecular cloning of a cell-surface glycoprotein that can potentially discriminate mesothelium from epithelium: its identification as vascular cell adhesion molecule 1. Br J Cancer (1995) 0.84
Molecular cloning of low-Ca(2+)-sensitive-type non-muscle alpha-actinin. Eur J Biochem (1994) 0.83
Fibroblast growth factor-1-inducible gene FR-17 encodes a nonmuscle alpha-actinin isoform. J Cell Physiol (1996) 0.82
Motility of rat ascites hepatoma cells, with reference to malignant characteristics in cancer metastasis. Gan (1978) 0.81
Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease). Nature (2000) 5.71
Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas. J Natl Cancer Inst (1998) 5.30
Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics. Mol Cell Biol (2000) 5.28
IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain. J Biol Chem (1999) 5.16
Identification of a neural alpha-catenin as a key regulator of cadherin function and multicellular organization. Cell (1992) 5.01
Structure of the promoter for chicken alpha 2 type I collagen gene. Proc Natl Acad Sci U S A (1981) 4.89
Regulation of lactate dehydrogenase and change of fermentation products in streptococci. J Bacteriol (1975) 4.60
Adoptive immunotherapy to lower postsurgical recurrence rates of hepatocellular carcinoma: a randomised trial. Lancet (2000) 4.60
Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor. Nature (2001) 4.55
Extrathoracic solitary fibrous tumors: their histological variability and potentially aggressive behavior. Hum Pathol (1999) 4.48
Cadherin cell-adhesion molecules in human epithelial tissues and carcinomas. Cancer Res (1989) 4.34
Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas. Proc Natl Acad Sci U S A (1995) 4.28
Complete nucleotide sequence of the 16S rRNA gene of Mycobacterium bovis BCG. J Bacteriol (1988) 4.10
Cloning and expression of the Mycobacterium bovis BCG gene for extracellular alpha antigen. J Bacteriol (1988) 3.97
Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase. Proc Natl Acad Sci U S A (1995) 3.94
Small adenocarcinoma of the lung. Histologic characteristics and prognosis. Cancer (1995) 3.83
The collagen gene: evidence for its evolutinary assembly by amplification of a DNA segment containing an exon of 54 bp. Cell (1980) 3.66
Rapid detection and evaluation of clinical characteristics of emerging multiple-drug-resistant gram-negative rods carrying the metallo-beta-lactamase gene blaIMP. Antimicrob Agents Chemother (1998) 3.57
An improved method for isolation of mouse pancreatic islets. Transplantation (1985) 3.52
The prognostic significance of amplification and overexpression of c-met and c-erb B-2 in human gastric carcinomas. Cancer (1999) 3.47
A new form of amyloid protein associated with chronic hemodialysis was identified as beta 2-microglobulin. Biochem Biophys Res Commun (1985) 3.40
Idiopathic pulmonary alveolar proteinosis as an autoimmune disease with neutralizing antibody against granulocyte/macrophage colony-stimulating factor. J Exp Med (1999) 3.36
Three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties. J Biol Chem (1999) 3.34
Soluble interleukin-6 receptor triggers osteoclast formation by interleukin 6. Proc Natl Acad Sci U S A (1993) 3.29
A role for hematopoietic stem cells in promoting angiogenesis. Cell (2000) 3.25
Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation. EMBO J (1999) 3.22
SOX9 enhances aggrecan gene promoter/enhancer activity and is up-regulated by retinoic acid in a cartilage-derived cell line, TC6. J Biol Chem (2000) 3.20
Enzymatic Adenylylation of Streptomycin and Spectinomycin by R-Factor-Resistant Escherichia coli. Infect Immun (1970) 3.02
Complete coding sequence and deduced primary structure of the human cartilage large aggregating proteoglycan, aggrecan. Human-specific repeats, and additional alternatively spliced forms. J Biol Chem (1991) 3.01
Two different laminin domains mediate the differentiation of human endothelial cells into capillary-like structures in vitro. Cell (1989) 3.00
Antitumor effect of genetically engineered mesenchymal stem cells in a rat glioma model. Gene Ther (2004) 2.97
Kabuki make-up (Niikawa-Kuroki) syndrome: a study of 62 patients. Am J Med Genet (1988) 2.94
Molecular cloning of a porcine gene syk that encodes a 72-kDa protein-tyrosine kinase showing high susceptibility to proteolysis. J Biol Chem (1991) 2.89
Cadherin dysfunction in a human cancer cell line: possible involvement of loss of alpha-catenin expression in reduced cell-cell adhesiveness. Cancer Res (1992) 2.89
Identification of an amino acid sequence in laminin mediating cell attachment, chemotaxis, and receptor binding. Cell (1987) 2.84
Sequence of the cDNA encoding the laminin B1 chain reveals a multidomain protein containing cysteine-rich repeats. Proc Natl Acad Sci U S A (1987) 2.82
Molecular cloning, expression, and gene localization of a fourth melanocortin receptor. J Biol Chem (1993) 2.81
Anti-inflammatory properties of a platelet-activating factor acetylhydrolase. Nature (1995) 2.79
Laminin, a multidomain protein. The A chain has a unique globular domain and homology with the basement membrane proteoglycan and the laminin B chains. J Biol Chem (1988) 2.74
Oxidative degradation of squalene by Arthrobacter species. Appl Microbiol (1975) 2.73
Early stages of motor neuron differentiation revealed by expression of homeobox gene Islet-1. Science (1992) 2.70
Cloning and characterization of the gene for immunogenic protein MPB64 of Mycobacterium bovis BCG. Infect Immun (1989) 2.62
[Testicular atrophy of mice induced by ethylene glycol mono alkyl ethers (author's transl)]. Sangyo Igaku (1979) 2.61
Mice lacking link protein develop dwarfism and craniofacial abnormalities. Nat Genet (1999) 2.58
Expression of E- and P-cadherin in gastric carcinomas. Cancer Res (1991) 2.56
Uterine sutures at prior caesarean section and placenta accreta in subsequent pregnancy: a case-control study. BJOG (2014) 2.56
A new method of diagnosing gastric intestinal metaplasia: narrow-band imaging with magnifying endoscopy. Endoscopy (2006) 2.52
Total synthesis of the gene for an alanine transfer ribonucleic acid from yeast. Nature (1970) 2.51
Enzymatic inactivation of streptomycin by R factor-resistant Escherichia coli. Nature (1968) 2.45
Exacerbation of autoimmune thyroid dysfunction after unilateral adrenalectomy in patients with Cushing's syndrome due to an adrenocortical adenoma. N Engl J Med (1990) 2.40
Osteoarthritis development in novel experimental mouse models induced by knee joint instability. Osteoarthritis Cartilage (2005) 2.36
E-cadherin gene mutations in human gastric carcinoma cell lines. Proc Natl Acad Sci U S A (1994) 2.35
Directed disruption of the tobacco ndhB gene impairs cyclic electron flow around photosystem I. Proc Natl Acad Sci U S A (1998) 2.34
Organization of rRNA genes in Mycobacterium bovis BCG. J Bacteriol (1987) 2.33
The laminin B2 chain has a multidomain structure homologous to the B1 chain. J Biol Chem (1987) 2.30
Glucose intolerance caused by a defect in the entero-insular axis: a study in gastric inhibitory polypeptide receptor knockout mice. Proc Natl Acad Sci U S A (1999) 2.29
Germ-line mutation of the hMSH6/GTBP gene in an atypical hereditary nonpolyposis colorectal cancer kindred. Cancer Res (1997) 2.28
Beta-catenin mutation in carcinoma of the uterine endometrium. Cancer Res (1998) 2.27
The complete sequence of perlecan, a basement membrane heparan sulfate proteoglycan, reveals extensive similarity with laminin A chain, low density lipoprotein-receptor, and the neural cell adhesion molecule. J Biol Chem (1991) 2.23
Growth and spread of hepatocellular carcinoma. A review of 240 consecutive autopsy cases. Cancer (1990) 2.22
Perlecan is essential for cartilage and cephalic development. Nat Genet (1999) 2.21
Codon usage and tRNA genes in eukaryotes: correlation of codon usage diversity with translation efficiency and with CG-dinucleotide usage as assessed by multivariate analysis. J Mol Evol (2001) 2.20
Hyperglycemia causes oxidative stress in pancreatic beta-cells of GK rats, a model of type 2 diabetes. Diabetes (1999) 2.19
A synthetic peptide containing the IKVAV sequence from the A chain of laminin mediates cell attachment, migration, and neurite outgrowth. J Biol Chem (1989) 2.17
The nasopharyngeal bacterial flora in children with otitis media with effusion. Eur Arch Otorhinolaryngol (1996) 2.16
Reproducible high yield of rat islets by stationary in vitro digestion following pancreatic ductal or portal venous collagenase injection. Transplantation (1987) 2.14
Studies on antioxidants: their carcinogenic and modifying effects on chemical carcinogenesis. Food Chem Toxicol (1987) 2.14
Transplantation of human tumors in nude mice. J Natl Cancer Inst (1976) 2.13
Identification of a phenotype-specific enhancer in the first intron of the rat collagen II gene. Proc Natl Acad Sci U S A (1987) 2.12
Complete primary structure of the rat cartilage proteoglycan core protein deduced from cDNA clones. J Biol Chem (1987) 2.11
Early stages of multistep hepatocarcinogenesis: adenomatous hyperplasia and early hepatocellular carcinoma. Hum Pathol (1991) 2.10
Clinicopathological and prognostic significance of EGFR, VEGF, and HER2 expression in cholangiocarcinoma. Br J Cancer (2007) 2.09
A randomized study of screening for ovarian cancer: a multicenter study in Japan. Int J Gynecol Cancer (2007) 2.07
Cloning and expression of the gene for the cross-reactive alpha antigen of Mycobacterium kansasii. Infect Immun (1990) 2.06
Over-expression of facilitative glucose transporter genes in human cancer. Biochem Biophys Res Commun (1990) 2.06
Telomestatin, a novel telomerase inhibitor from Streptomyces anulatus. J Am Chem Soc (2001) 2.05
Molecular cloning of hyoscyamine 6 beta-hydroxylase, a 2-oxoglutarate-dependent dioxygenase, from cultured roots of Hyoscyamus niger. J Biol Chem (1991) 2.03
Correlation between splicing sites within an intron and their sequence complementarity with U1 RNA. Cell (1980) 2.02
High dose rate brachytherapy for carcinoma of the uterine cervix: comparison of two different fractionation regimens. Int J Radiat Oncol Biol Phys (1995) 2.02
Analysis of genes for bilirubin UDP-glucuronosyltransferase in Gilbert's syndrome. Lancet (1995) 2.01
Immunologic reactions in amyotrophic lateral sclerosis brain and spinal cord tissue. Am J Pathol (1992) 2.01
Full-length sequence, localization, and chromosomal mapping of ameloblastin. A novel tooth-specific gene. J Biol Chem (1996) 2.00
Investigating the relationship between stroke and obstructive sleep apnea. Stroke (1996) 2.00
The structure of inducing factors for virginiamycin production in Streptomyces virginiae. J Antibiot (Tokyo) (1987) 1.99
Quasiperiodicity and chaos in cardiac fibrillation. J Clin Invest (1997) 1.99
Agr, an Agravitropic locus of Arabidopsis thaliana, encodes a novel membrane-protein family member. Plant Cell Physiol (1998) 1.98
Peculiar feature of the organization of rRNA genes of the Chlorella chloroplast DNA. Nucleic Acids Res (1986) 1.98
Involvement of oxygen-sensitive pyruvate formate-lyase in mixed-acid fermentation by Streptococcus mutans under strictly anaerobic conditions. J Bacteriol (1982) 1.97
Early hepatocellular carcinoma as an entity with a high rate of surgical cure. Hepatology (1998) 1.97
Modulation of EphA receptor function by coexpressed ephrinA ligands on retinal ganglion cell axons. Neuron (1999) 1.97
Pgp-1hi T lymphocytes accumulate with age in mice and respond poorly to concanavalin A. Eur J Immunol (1989) 1.95
Phase I/II study of S-1 combined with cisplatin in patients with advanced gastric cancer. Br J Cancer (2003) 1.95
Embryotoxic effects of ethylene glycol monomethyl ether in mice. Toxicology (1981) 1.95