Published in Proc Natl Acad Sci U S A on January 01, 1979
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Procoat, the precursor of M13 coat protein, requires an electrochemical potential for membrane insertion. Proc Natl Acad Sci U S A (1980) 2.57
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Soluble precursor of an integral membrane protein: synthesis of procoat protein in Escherichia coli infected with bacteriophage M13. Proc Natl Acad Sci U S A (1979) 1.99
Isolation of the Escherichia coli leader peptidase gene and effects of leader peptidase overproduction in vivo. Proc Natl Acad Sci U S A (1981) 1.96
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Post-translational cleavage of presecretory proteins with an extract of rough microsomes from dog pancreas containing signal peptidase activity. Proc Natl Acad Sci U S A (1977) 3.54
Detection of prokaryotic signal peptidase in an Escherichia coli membrane fraction: endoproteolytic cleavage of nascent f1 pre-coat protein. Proc Natl Acad Sci U S A (1978) 3.48
Extracellular labeling of nascent polypeptides traversing the membrane of Escherichia coli. Proc Natl Acad Sci U S A (1977) 3.16
Precursors of three exported proteins in Escherichia coli. Proc Natl Acad Sci U S A (1978) 2.91
Asymmetric orientation of phage M13 coat protein in Escherichia coli cytoplasmic membranes and in synthetic lipid vesicles. Proc Natl Acad Sci U S A (1976) 2.84
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Localization of polyribosomes containing alkaline phosphatase nascent polypeptides on membranes of Escherichia coli. J Bacteriol (1974) 1.78
Identification and characterization of the in vitro synthesized gene products of bacteriophage M13. J Virol (1975) 1.75
Synthesis of phage M13 coat protein and its assembly into membranes in vitro. Proc Natl Acad Sci U S A (1978) 1.69
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Binding, eclipse, and penetration of the filamentous bacteriophage M13 in intact and disrupted cells. Virology (1974) 1.59
Heterogeneity of membrane vesicles from Escherichia coli and their subfractionation with antibody to ATPase. Proc Natl Acad Sci U S A (1974) 1.54
Association of the major coat protein of fd bacteriophage with phospholipid vesicles. Biochim Biophys Acta (1978) 0.99
Identification of a cyclic-AMP-responsive element within the rat somatostatin gene. Proc Natl Acad Sci U S A (1986) 10.41
RNA synthesis initiates in vitro conversion of M13 DNA to its replicative form. Proc Natl Acad Sci U S A (1972) 8.09
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Initiation of DNA synthesis: synthesis of phiX174 replicative form requires RNA synthesis resistant to rifampicin. Proc Natl Acad Sci U S A (1972) 5.74
Sec18p (NSF)-driven release of Sec17p (alpha-SNAP) can precede docking and fusion of yeast vacuoles. Cell (1996) 5.18
Conserved residues of the leader peptide are essential for cleavage by leader peptidase. J Biol Chem (1985) 4.89
The purified E. coli integral membrane protein SecY/E is sufficient for reconstitution of SecA-dependent precursor protein translocation. Cell (1990) 4.78
CoREST: a functional corepressor required for regulation of neural-specific gene expression. Proc Natl Acad Sci U S A (1999) 4.59
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The ATPase activity of SecA is regulated by acidic phospholipids, SecY, and the leader and mature domains of precursor proteins. Cell (1990) 4.00
SecA promotes preprotein translocation by undergoing ATP-driven cycles of membrane insertion and deinsertion. Cell (1994) 3.95
The GTPase Ypt7p of Saccharomyces cerevisiae is required on both partner vacuoles for the homotypic fusion step of vacuole inheritance. EMBO J (1995) 3.76
The binding cascade of SecB to SecA to SecY/E mediates preprotein targeting to the E. coli plasma membrane. Cell (1990) 3.58
Defining the functions of trans-SNARE pairs. Nature (1998) 3.52
Multiple methods of visualizing the yeast vacuole permit evaluation of its morphology and inheritance during the cell cycle. J Cell Biol (1987) 3.48
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A vacuolar v-t-SNARE complex, the predominant form in vivo and on isolated vacuoles, is disassembled and activated for docking and fusion. J Cell Biol (1998) 3.44
Leader peptidase catalyzes the release of exported proteins from the outer surface of the Escherichia coli plasma membrane. J Biol Chem (1985) 3.35
SecA protein hydrolyzes ATP and is an essential component of the protein translocation ATPase of Escherichia coli. EMBO J (1989) 3.33
Sequence of the leader peptidase gene of Escherichia coli and the orientation of leader peptidase in the bacterial envelope. J Biol Chem (1983) 3.22
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Synthesis, assembly into the cytoplasmic membrane, and proteolytic processing of the precursor of coliphage M13 coat protein. J Biol Chem (1980) 3.09
Delta mu H+ and ATP function at different steps of the catalytic cycle of preprotein translocase. Cell (1991) 2.98
Trigger factor: a soluble protein that folds pro-OmpA into a membrane-assembly-competent form. Proc Natl Acad Sci U S A (1987) 2.97
Phase variation: evolution of a controlling element. Science (1980) 2.96
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Three pure chaperone proteins of Escherichia coli--SecB, trigger factor and GroEL--form soluble complexes with precursor proteins in vitro. EMBO J (1989) 2.89
Variations in polyoma virus genotype in relation to tumor induction in mice. Characterization of wild type strains with widely differing tumor profiles. Am J Pathol (1987) 2.84
Asymmetric orientation of phage M13 coat protein in Escherichia coli cytoplasmic membranes and in synthetic lipid vesicles. Proc Natl Acad Sci U S A (1976) 2.84
Purification and characterization of leader (signal) peptidase from Escherichia coli. J Biol Chem (1980) 2.76
Identification of PN1, a predominant voltage-dependent sodium channel expressed principally in peripheral neurons. Proc Natl Acad Sci U S A (1997) 2.75
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Distinct catalytic roles of the SecYE, SecG and SecDFyajC subunits of preprotein translocase holoenzyme. EMBO J (1997) 2.60
SecA membrane cycling at SecYEG is driven by distinct ATP binding and hydrolysis events and is regulated by SecD and SecF. Cell (1995) 2.58
Homotypic vacuole fusion requires Sec17p (yeast alpha-SNAP) and Sec18p (yeast NSF). EMBO J (1996) 2.52
Docking of yeast vacuoles is catalyzed by the Ras-like GTPase Ypt7p after symmetric priming by Sec18p (NSF). J Cell Biol (1997) 2.51
Mechanisms of membrane assembly: effects of energy poisons on the conversion of soluble M13 coliphage procoat to membrane-bound coat protein. Proc Natl Acad Sci U S A (1980) 2.51
G-protein ligands inhibit in vitro reactions of vacuole inheritance. J Cell Biol (1994) 2.51
ProOmpA is stabilized for membrane translocation by either purified E. coli trigger factor or canine signal recognition particle. Cell (1988) 2.42
A new form of DNA polymerase 3 and a copolymerase replicate a long, single-stranded primer-template. Proc Natl Acad Sci U S A (1973) 2.42
Effects of two sec genes on protein assembly into the plasma membrane of Escherichia coli. J Biol Chem (1985) 2.40
Use of phoA fusions to study the topology of the Escherichia coli inner membrane protein leader peptidase. J Bacteriol (1989) 2.38
SecA protein, a peripheral protein of the Escherichia coli plasma membrane, is essential for the functional binding and translocation of proOmpA. EMBO J (1989) 2.33
Three v-SNAREs and two t-SNAREs, present in a pentameric cis-SNARE complex on isolated vacuoles, are essential for homotypic fusion. J Cell Biol (1999) 2.31
The co-repressor mSin3A is a functional component of the REST-CoREST repressor complex. J Biol Chem (2000) 2.28
In vitro reactions of vacuole inheritance in Saccharomyces cerevisiae. J Cell Biol (1992) 2.28
Both ATP and the electrochemical potential are required for optimal assembly of pro-OmpA into Escherichia coli inner membrane vesicles. Proc Natl Acad Sci U S A (1986) 2.16
The docking stage of yeast vacuole fusion requires the transfer of proteins from a cis-SNARE complex to a Rab/Ypt protein. J Cell Biol (2000) 2.13
The isolation of homogeneous leader peptidase from a strain of Escherichia coli which overproduces the enzyme. J Biol Chem (1982) 2.11
ProOmpA spontaneously folds in a membrane assembly competent state which trigger factor stabilizes. EMBO J (1988) 2.10
Intervacuole exchange in the yeast zygote: a new pathway in organelle communication. Science (1988) 2.06
Soluble precursor of an integral membrane protein: synthesis of procoat protein in Escherichia coli infected with bacteriophage M13. Proc Natl Acad Sci U S A (1979) 1.99
Genetic mapping of the Escherichia coli leader (signal) peptidase gene (lep): a new approach for determining the map position of a cloned gene. J Bacteriol (1983) 1.98
Isolation of mutants in M13 coat protein that affect its synthesis, processing, and assembly into phage. J Biol Chem (1985) 1.96
Isolation of the Escherichia coli leader peptidase gene and effects of leader peptidase overproduction in vivo. Proc Natl Acad Sci U S A (1981) 1.96
Identification of a region in the human vasoactive intestinal polypeptide gene responsible for regulation by cyclic AMP. J Biol Chem (1987) 1.96
Genomic organization and deduced amino acid sequence of a putative sodium channel gene in Drosophila. Science (1987) 1.92
The SecA and SecY subunits of translocase are the nearest neighbors of a translocating preprotein, shielding it from phospholipids. EMBO J (1993) 1.91
M13 procoat and a pre-immunoglobulin share processing specificity but use different membrane receptor mechanisms. Proc Natl Acad Sci U S A (1983) 1.90
Asymmetric orientation of a phage coat protein in cytoplasmic membrane of Escherichia coli. Proc Natl Acad Sci U S A (1975) 1.89
Molecular characterization of VAC1, a gene required for vacuole inheritance and vacuole protein sorting. J Biol Chem (1992) 1.89
Vam7p, a vacuolar SNAP-25 homolog, is required for SNARE complex integrity and vacuole docking and fusion. EMBO J (1998) 1.89
The "trigger factor cycle" includes ribosomes, presecretory proteins, and the plasma membrane. Cell (1988) 1.86
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Phosphatidylinositol 4,5-bisphosphate regulates two steps of homotypic vacuole fusion. Mol Biol Cell (2000) 1.80
Silencing the type II sodium channel gene: a model for neural-specific gene regulation. Neuron (1992) 1.80
Interactions of melittin, a preprotein model, with detergents. Biochemistry (1979) 1.80
The SecDFyajC domain of preprotein translocase controls preprotein movement by regulating SecA membrane cycling. EMBO J (1997) 1.74
Sequential action of two GTPases to promote vacuole docking and fusion. EMBO J (2000) 1.73
Transformation by polyoma virus is drastically reduced by substitution of phenylalanine for tyrosine at residue 315 of middle-sized tumor antigen. Proc Natl Acad Sci U S A (1984) 1.71
SecA protein needs both acidic phospholipids and SecY/E protein for functional high-affinity binding to the Escherichia coli plasma membrane. J Biol Chem (1991) 1.71
Synthesis of phage M13 coat protein and its assembly into membranes in vitro. Proc Natl Acad Sci U S A (1978) 1.69
The CGTCA sequence motif is essential for biological activity of the vasoactive intestinal peptide gene cAMP-regulated enhancer. Proc Natl Acad Sci U S A (1988) 1.68
Rho1p and Cdc42p act after Ypt7p to regulate vacuole docking. EMBO J (2001) 1.65
Ergosterol is required for the Sec18/ATP-dependent priming step of homotypic vacuole fusion. EMBO J (2001) 1.65
Polyomavirus tumor induction in mice: influences of viral coding and noncoding sequences on tumor profiles. J Virol (1987) 1.65
SecY, SecE, and band 1 form the membrane-embedded domain of Escherichia coli preprotein translocase. J Biol Chem (1992) 1.65
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A heterodimer of thioredoxin and I(B)2 cooperates with Sec18p (NSF) to promote yeast vacuole inheritance. J Cell Biol (1997) 1.60
LMA1 binds to vacuoles at Sec18p (NSF), transfers upon ATP hydrolysis to a t-SNARE (Vam3p) complex, and is released during fusion. Cell (1998) 1.59
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Trigger factor depletion or overproduction causes defective cell division but does not block protein export. J Bacteriol (1990) 1.59
Determination of four biochemically distinct, sequential stages during vacuole inheritance in vitro. J Cell Biol (1994) 1.56
Bacterial leader peptidase, a membrane protein without a leader peptide, uses the same export pathway as pre-secretory proteins. Cell (1984) 1.56
Specific recognition of the leader region of precursor proteins is required for the activation of translocation ATPase of Escherichia coli. Proc Natl Acad Sci U S A (1989) 1.53
A single zinc finger motif in the silencing factor REST represses the neural-specific type II sodium channel promoter. Proc Natl Acad Sci U S A (1997) 1.52
The biosynthesis of membrane-bound M13 coat protein. Energetics and assembly intermediates. J Biol Chem (1982) 1.50
Biogenesis of the gram-negative bacterial envelope. Cell (1997) 1.49
Tuna cytochrome c at 2.0 A resolution. III. Coordinate optimization and comparison of structures. J Biol Chem (1977) 1.44
The secY protein can act post-translationally to promote bacterial protein export. J Biol Chem (1986) 1.44
Vacuole acidification is required for trans-SNARE pairing, LMA1 release, and homotypic fusion. Proc Natl Acad Sci U S A (1999) 1.40
The cytoplasmic carboxy terminus of M13 procoat is required for the membrane insertion of its central domain. Nature (1986) 1.40
Melittin forms crystals which are suitable for high resolution X-ray structural analysis and which reveal a molecular 2-fold axis of symmetry. J Biol Chem (1980) 1.40