Published in J Cell Biol on September 01, 1985
Taxol-resistant epithelial ovarian tumors are associated with altered expression of specific beta-tubulin isotypes. J Clin Invest (1997) 2.96
Identification of conserved isotype-defining variable region sequences for four vertebrate beta tubulin polypeptide classes. Proc Natl Acad Sci U S A (1986) 2.71
In vivo microtubules are copolymers of available beta-tubulin isotypes: localization of each of six vertebrate beta-tubulin isotypes using polyclonal antibodies elicited by synthetic peptide antigens. J Cell Biol (1987) 2.30
Production of hydrogen peroxide by transforming growth factor-beta 1 and its involvement in induction of egr-1 in mouse osteoblastic cells. J Cell Biol (1994) 2.27
Six mouse alpha-tubulin mRNAs encode five distinct isotypes: testis-specific expression of two sister genes. Mol Cell Biol (1986) 2.07
The mammalian beta-tubulin repertoire: hematopoietic expression of a novel, heterologous beta-tubulin isotype. J Cell Biol (1986) 1.97
Autoregulated changes in stability of polyribosome-bound beta-tubulin mRNAs are specified by the first 13 translated nucleotides. Mol Cell Biol (1988) 1.80
The tubulin code: molecular components, readout mechanisms, and functions. J Cell Biol (2014) 1.60
Differential utilization of beta-tubulin isotypes in differentiating neurites. J Cell Biol (1989) 1.54
The multitubulin hypothesis revisited: what have we learned? J Cell Biol (1987) 1.50
Internalization of Staphylococcus aureus by endothelial cells induces cytokine gene expression. Infect Immun (1995) 1.45
Relative quantification of stable isotope labeled peptides using a linear ion trap-Orbitrap hybrid mass spectrometer. Anal Chem (2007) 1.40
Posttranslational modification of class III beta-tubulin. Proc Natl Acad Sci U S A (1990) 1.34
Differential distribution of beta-tubulin isotypes in cerebellum. EMBO J (1988) 1.18
Subpellicular and flagellar microtubules of Trypanosoma brucei brucei contain the same alpha-tubulin isoforms. J Cell Biol (1987) 1.17
A pachygyria-causing alpha-tubulin mutation results in inefficient cycling with CCT and a deficient interaction with TBCB. Mol Biol Cell (2008) 1.12
In vivo coassembly of a divergent beta-tubulin subunit (c beta 6) into microtubules of different function. J Cell Biol (1987) 1.11
Sequence and expression of the chicken beta 5- and beta 4-tubulin genes define a pair of divergent beta-tubulins with complementary patterns of expression. Mol Cell Biol (1986) 1.11
Complete sequence of three alpha-tubulin cDNAs in Chinese hamster ovary cells: each encodes a distinct alpha-tubulin isoprotein. Mol Cell Biol (1986) 1.11
Multiple hormone-inducible enhancers as mediators of differential transcription. Mol Cell Biol (1986) 1.09
Complex regulation and functional versatility of mammalian alpha- and beta-tubulin isotypes during the differentiation of testis and muscle cells. J Cell Biol (1988) 1.06
Disease-associated mutations in TUBA1A result in a spectrum of defects in the tubulin folding and heterodimer assembly pathway. Hum Mol Genet (2010) 1.06
Isotypes of alpha-tubulin are differentially regulated during neuronal maturation. J Cell Biol (1987) 1.00
Structural analysis of mutations in the Drosophila beta 2-tubulin isoform reveals regions in the beta-tubulin molecular required for general and for tissue-specific microtubule functions. Genetics (1995) 0.99
Generation of antisera that discriminate among mammalian alpha-tubulins: introduction of specialized isotypes into cultured cells results in their coassembly without disruption of normal microtubule function. J Cell Biol (1988) 0.98
Cell type-specific reduction of beta tubulin isotypes synthesized in the developing gerbil organ of Corti. J Neurocytol (2003) 0.97
Beta class II tubulin predominates in normal and tumor breast tissues. Breast Cancer Res (2003) 0.97
Expression and localization of the cystic fibrosis transmembrane conductance regulator mRNA and its protein in rat brain. J Clin Invest (1995) 0.95
A kinase-negative mutant of S49 mouse lymphoma cells is defective in posttranslational maturation of catalytic subunit of cyclic AMP-dependent protein kinase. Mol Cell Biol (1991) 0.94
Alternative 3' processing of Xenopus alpha-tubulin mRNAs; efficient use of a CAUAAA polyadenylation signal. Nucleic Acids Res (1992) 0.92
Modulation of cellular macromolecular synthesis by coronavirus: implication for pathogenesis. J Virol (1994) 0.88
Genome-wide analysis reveals novel and discrete functions for tubulin carboxy-terminal tails. Curr Biol (2014) 0.85
A proteomic comparison of immature and mature mouse gonadotrophs reveals novel differentially expressed nuclear proteins that regulate gonadotropin gene transcription and RNA splicing. Biol Reprod (2008) 0.84
A survey of the alpha-tubulin gene family in chicken: unexpected sequence heterogeneity in the polypeptides encoded by five expressed genes. EMBO J (1988) 0.83
Regulation of motility of myogenic cells in filling limb muscle anlagen by Pitx2. PLoS One (2012) 0.80
Enhanced expression of superoxide dismutase messenger RNA in viral myocarditis. An SH-dependent reduction of its expression and myocardial injury. J Clin Invest (1993) 0.80
Roles of beta-tubulin residues Ala428 and Thr429 in microtubule formation in vivo. J Biol Chem (2008) 0.79
Novel α-tubulin mutation disrupts neural development and tubulin proteostasis. Dev Biol (2015) 0.78
α-Tubulin mutations alter oryzalin affinity and microtubule assembly properties to confer dinitroaniline resistance. Eukaryot Cell (2010) 0.77
The alpha-tubulin gene family expressed during cell differentiation in Naegleria gruberi. J Cell Biol (1988) 0.77
Effect of CH-35, a novel anti-tumor colchicine analogue, on breast cancer cells overexpressing the βIII isotype of tubulin. Invest New Drugs (2015) 0.76
Directing lineage specification of human mesenchymal stem cells by decoupling electrical stimulation and physical patterning on unmodified graphene. Nanoscale (2016) 0.75
Spatio-temporal dynamics of β-tubulin isotypes during the development of the sensory auditory organ in rat. Histochem Cell Biol (2015) 0.75
Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol (1975) 503.08
Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I. J Mol Biol (1977) 205.11
Studies on transformation of Escherichia coli with plasmids. J Mol Biol (1983) 116.81
Screening lambdagt recombinant clones by hybridization to single plaques in situ. Science (1977) 83.82
Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing. J Mol Biol (1980) 61.16
Spliced early mRNAs of simian virus 40. Proc Natl Acad Sci U S A (1978) 18.67
Number and evolutionary conservation of alpha- and beta-tubulin and cytoplasmic beta- and gamma-actin genes using specific cloned cDNA probes. Cell (1980) 17.55
Isolation of the beta-tubulin gene from yeast and demonstration of its essential function in vivo. Cell (1983) 6.22
Identification of clones that encode chicken tropomyosin by direct immunological screening of a cDNA expression library. Proc Natl Acad Sci U S A (1983) 6.00
Evolutionary history of a multigene family: an expressed human beta-tubulin gene and three processed pseudogenes. Cell (1983) 4.26
Nucleotide sequence and evolution of a mammalian alpha-tubulin messenger RNA. J Mol Biol (1981) 3.18
Identification of two human beta-tubulin isotypes. Mol Cell Biol (1983) 3.15
Sequence of an expressed human beta-tubulin gene containing ten Alu family members. Nucleic Acids Res (1984) 3.08
Expression of human alpha-tubulin genes: interspecies conservation of 3' untranslated regions. Mol Cell Biol (1983) 2.85
Mutation in a testis-specific beta-tubulin in Drosophila: analysis of its effects on meiosis and map location of the gene. Cell (1980) 2.64
Mutation in a structural gene for a beta-tubulin specific to testis in Drosophila melanogaster. Proc Natl Acad Sci U S A (1979) 2.62
Sequence of a cDNA clone encoding mouse glial fibrillary acidic protein: structural conservation of intermediate filaments. Proc Natl Acad Sci U S A (1984) 2.51
Involvement of the carboxyl-terminal domain of tubulin in the regulation of its assembly. Proc Natl Acad Sci U S A (1984) 2.11
Regulation of tubulin and actin mRNA production in rat brain: expression of a new beta-tubulin mRNA with development. Mol Cell Biol (1983) 1.94
The nucleotide sequence of rat alpha-tubulin: 3'-end characteristics, and evolutionary conservation. Nucleic Acids Res (1981) 1.58
Structural features and restricted expression of a human alpha-tubulin gene. Nucleic Acids Res (1985) 1.51
Programmed expression of beta-tubulin genes during development and differentiation of the chicken. J Cell Biol (1984) 1.48
Sequence of a highly divergent beta tubulin gene reveals regional heterogeneity in the beta tubulin polypeptide. J Cell Biol (1984) 1.37
Haploid expression of a mouse testis alpha-tubulin gene. Science (1984) 1.34
Differential expression of two neural cell-specific beta-tubulin mRNAs during rat brain development. Mol Cell Biol (1984) 1.31
Pausing and termination of human RNA polymerase II transcription at a procaryotic terminator. Mol Cell Biol (1983) 1.04
Number and evolutionary conservation of alpha- and beta-tubulin and cytoplasmic beta- and gamma-actin genes using specific cloned cDNA probes. Cell (1980) 17.55
Defining community acquired pneumonia severity on presentation to hospital: an international derivation and validation study. Thorax (2003) 9.54
Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2. Nature (1987) 8.87
RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. Nature (1998) 5.98
Inhaled corticosteroid use and bone-mineral density in patients with asthma. Lancet (2000) 5.66
Evolutionary history of a multigene family: an expressed human beta-tubulin gene and three processed pseudogenes. Cell (1983) 4.26
A cytoplasmic chaperonin that catalyzes beta-actin folding. Cell (1992) 3.50
An oral preparation to release drugs in the human colon. Br J Clin Pharmacol (1982) 3.49
Contemporary use of antibiotics in 1089 adults presenting with acute lower respiratory tract illness in general practice in the U.K.: implications for developing management guidelines. Respir Med (1997) 3.38
Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin. Cell (1998) 3.33
Dynamic association of proteasomal machinery with the centrosome. J Cell Biol (1999) 3.30
Identification of two human beta-tubulin isotypes. Mol Cell Biol (1983) 3.15
Evidence that a human beta-tubulin pseudogene is derived from its corresponding mRNA. Nature (1982) 3.08
Sequence of an expressed human beta-tubulin gene containing ten Alu family members. Nucleic Acids Res (1984) 3.08
Microtubule-associated protein MAP2 shares a microtubule binding motif with tau protein. Science (1988) 3.04
Living near a main road and the risk of wheezing illness in children. Am J Respir Crit Care Med (2001) 2.94
Expression of human alpha-tubulin genes: interspecies conservation of 3' untranslated regions. Mol Cell Biol (1983) 2.85
Projection domains of MAP2 and tau determine spacings between microtubules in dendrites and axons. Nature (1992) 2.82
The FT210 cell line is a mouse G2 phase mutant with a temperature-sensitive CDC2 gene product. Cell (1990) 2.73
Activation at M-phase of a protein kinase encoded by a starfish homologue of the cell cycle control gene cdc2+. Nature (1988) 2.71
Bicistronic vector for the creation of stable mammalian cell lines that predisposes all antibiotic-resistant cells to express recombinant protein. Biotechniques (1996) 2.60
Pathway leading to correctly folded beta-tubulin. Cell (1996) 2.55
Sequence of a cDNA clone encoding mouse glial fibrillary acidic protein: structural conservation of intermediate filaments. Proc Natl Acad Sci U S A (1984) 2.51
Increased microtubule stability and alpha tubulin acetylation in cells transfected with microtubule-associated proteins MAP1B, MAP2 or tau. J Cell Sci (1992) 2.42
Neurofilament gene expression: a major determinant of axonal caliber. Proc Natl Acad Sci U S A (1987) 2.36
The microtubule binding domain of microtubule-associated protein MAP1B contains a repeated sequence motif unrelated to that of MAP2 and tau. J Cell Biol (1989) 2.34
Chaperonin-mediated folding of vertebrate actin-related protein and gamma-tubulin. J Cell Biol (1993) 2.28
Dietary antioxidant vitamin intake and lung function in the general population. Am J Respir Crit Care Med (1995) 2.25
Genetics, evolution, and expression of the 68,000-mol-wt neurofilament protein: isolation of a cloned cDNA probe. J Cell Biol (1985) 2.20
Aberrant CFTR-dependent HCO3- transport in mutations associated with cystic fibrosis. Nature (2001) 2.19
Organization of microtubules in dendrites and axons is determined by a short hydrophobic zipper in microtubule-associated proteins MAP2 and tau. Nature (1989) 2.15
Intracellular immunoglobulin chain synthesis in non-secreting variants of a mouse myeloma: detection of inactive light-chain messenger RNA. J Mol Biol (1974) 2.14
Two cofactors and cytoplasmic chaperonin are required for the folding of alpha- and beta-tubulin. Mol Cell Biol (1993) 2.11
Six mouse alpha-tubulin mRNAs encode five distinct isotypes: testis-specific expression of two sister genes. Mol Cell Biol (1986) 2.07
ADH action: evidence for a membrane shuttle mechanism. Ann N Y Acad Sci (1981) 2.03
Free intermingling of mammalian beta-tubulin isotypes among functionally distinct microtubules. Cell (1987) 2.02
Procyclic acidic repetitive protein (PARP) genes located in an unusually small alpha-amanitin-resistant transcription unit: PARP promoter activity assayed by transient DNA transfection of Trypanosoma brucei. Mol Cell Biol (1990) 2.01
The mammalian beta-tubulin repertoire: hematopoietic expression of a novel, heterologous beta-tubulin isotype. J Cell Biol (1986) 1.97
Tubulin subunits exist in an activated conformational state generated and maintained by protein cofactors. J Cell Biol (1997) 1.97
GFAP is necessary for the integrity of CNS white matter architecture and long-term maintenance of myelination. Neuron (1996) 1.91
Diverse mechanisms in the generation of human beta-tubulin pseudogenes. Science (1982) 1.87
Vitamin E supplements in asthma: a parallel group randomised placebo controlled trial. Thorax (2004) 1.86
Secretion of beta-amyloid precursor protein cleaved at the amino terminus of the beta-amyloid peptide. Nature (1993) 1.85
Permeability properties of the intact mammalian bladder epithelium. Am J Physiol (1996) 1.84
Na+ transport by rabbit urinary bladder, a tight epithelium. J Membr Biol (1976) 1.84
ADP ribosylation factor-like protein 2 (Arl2) regulates the interaction of tubulin-folding cofactor D with native tubulin. J Cell Biol (2000) 1.76
Isolation of separate mRNAs for alpha- and beta-tubulin and characterization of the corresponding in vitro translation products. Cell (1978) 1.73
Hypoxia potentiates nitric oxide synthesis and transiently increases cytosolic calcium levels in pulmonary artery endothelial cells. Eur Respir J (1995) 1.72
Prefoldin-nascent chain complexes in the folding of cytoskeletal proteins. J Cell Biol (1999) 1.72
The alpha- and beta-tubulin folding pathways. Trends Cell Biol (1997) 1.70
The mechanism of Na+ transport by rabbit urinary bladder. J Membr Biol (1976) 1.70
Effect of maternal asthma, exacerbations and asthma medication use on congenital malformations in offspring: a UK population-based study. Thorax (2008) 1.68
Nystatin as a probe for investigating the electrical properties of a tight epithelium. J Gen Physiol (1977) 1.59
VSG gene 118 is transcribed from a cotransposed pol I-like promoter. Cell (1987) 1.59
Mammalian mitochondrial chaperonin 60 functions as a single toroidal ring. J Biol Chem (1992) 1.59
CT differentiation of tuberculous peritonitis and peritoneal carcinomatosis. AJR Am J Roentgenol (1996) 1.59
Immuno and functional characterization of CFTR in submandibular and pancreatic acinar and duct cells. Am J Physiol (1997) 1.56
The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology. Tuberculosis (Edinb) (2003) 1.55
Multiple functional P2X and P2Y receptors in the luminal and basolateral membranes of pancreatic duct cells. Am J Physiol (1999) 1.55
Three expressed sequences within the human beta-tubulin multigene family each define a distinct isotype. J Mol Biol (1985) 1.54
Radiologic features of vasculitis involving the gastrointestinal tract. Radiographics (2000) 1.54
Incorporation of cytoplasmic vesicles into apical membrane of mammalian urinary bladder epithelium. Nature (1982) 1.53
Recent trends of syphilis prevalence in normal population in Korea-1986. J Korean Med Sci (1988) 1.53
Processes involved in the development of latent fingerprints using the cyanoacrylate fuming method. J Forensic Sci (2001) 1.52
Respiratory symptoms in patients with treated hypothyroidism and inflammatory bowel disease. Thorax (2003) 1.51
Structural features and restricted expression of a human alpha-tubulin gene. Nucleic Acids Res (1985) 1.51
Drugs of dependence though not of abuse: fenfluramine and imipramine. Br Med J (1971) 1.50
Inflammatory pseudotumor of the liver in patients with recurrent pyogenic cholangitis: CT-histopathologic correlation. Radiology (1999) 1.48
Evolutionary conservation of the human homologue of the yeast cell cycle control gene cdc2 and assignment of Cd2 to chromosome 10. Hum Genet (1988) 1.47
Specificity in chaperonin-mediated protein folding. Nature (1995) 1.47
Purification and sequence of messenger RNA for immunoglobulin light chains. Nat New Biol (1973) 1.46
Tubulin folding cofactors as GTPase-activating proteins. GTP hydrolysis and the assembly of the alpha/beta-tubulin heterodimer. J Biol Chem (1999) 1.46
Staphylococcus aureus associated with toxic shock syndrome: phage typing and toxin capability testing. Ann Intern Med (1982) 1.45
Chronic fenfluramine administration: some cerebral effects. Br Med J (1971) 1.45
Radiologic findings of abdominal polyarteritis nodosa. AJR Am J Roentgenol (2000) 1.44
Hippocrates on necrotising fasciitis. Lancet (1994) 1.43
Reversible segmental left ventricular dysfunction after coronary angioplasty. Circulation (1990) 1.43
Structural variation among human beta-tubulin genes. Proc Natl Acad Sci U S A (1981) 1.42
Chaperonin-mediated folding of actin and tubulin. J Cell Biol (1996) 1.42
CT and MR imaging findings of bowel ischemia from various primary causes. Radiographics (2000) 1.40
Basolateral membrane potential of a tight epithelium: ionic diffusion and electrogenic pumps. J Membr Biol (1978) 1.40
Active and passive properties of rabbit descending colon: a microelectrode and nystatin study. J Membr Biol (1979) 1.40
Anomalous placement of introns in a member of the intermediate filament multigene family: an evolutionary conundrum. Mol Cell Biol (1986) 1.39