Published in J Biol Chem on April 25, 1985
Cellular targets of infection and route of viral dissemination after an intravaginal inoculation of simian immunodeficiency virus into rhesus macaques. J Exp Med (1996) 5.35
Ultrastructural analysis of the dynactin complex: an actin-related protein is a component of a filament that resembles F-actin. J Cell Biol (1994) 3.74
Role of fascin in filopodial protrusion. J Cell Biol (2006) 3.52
Migrastatin analogues target fascin to block tumour metastasis. Nature (2010) 2.84
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Drosophila singed, a fascin homolog, is required for actin bundle formation during oogenesis and bristle extension. J Cell Biol (1994) 2.32
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Fascin, an actin-bundling protein, induces membrane protrusions and increases cell motility of epithelial cells. Mol Biol Cell (1998) 1.86
Preliminary biochemical characterization of the stereocilia and cuticular plate of hair cells of the chick cochlea. J Cell Biol (1989) 1.74
beta-Catenin associates with the actin-bundling protein fascin in a noncadherin complex. J Cell Biol (1996) 1.70
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Independent prognostic value of fascin immunoreactivity in stage I nonsmall cell lung cancer. Br J Cancer (2003) 1.55
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Fascin, an echinoid actin-bundling protein, is a homolog of the Drosophila singed gene product. Proc Natl Acad Sci U S A (1993) 1.49
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Intrinsic dynamic behavior of fascin in filopodia. Mol Biol Cell (2007) 1.39
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Fascin expression in human embryonic, fetal, and normal adult tissue. J Histochem Cytochem (2007) 1.30
Characterization of cell-matrix adhesion requirements for the formation of fascin microspikes. Mol Biol Cell (1997) 1.22
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Mechanism of actin filament bundling by fascin. J Biol Chem (2011) 1.18
Single amino acid mutations in Drosophila fascin disrupt actin bundling function in vivo. Genetics (1996) 1.16
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Increased expression of fascin, motility associated protein, in cell cultures derived from ovarian cancer and in borderline and carcinomatous ovarian tumors. Clin Exp Metastasis (2000) 1.14
Characterization of 83-kilodalton nonmuscle caldesmon from cultured rat cells: stimulation of actin binding of nonmuscle tropomyosin and periodic localization along microfilaments like tropomyosin. J Cell Biol (1988) 1.08
Molecular mechanism of fascin function in filopodial formation. J Biol Chem (2012) 0.99
Microinjection of nonmuscle and smooth muscle caldesmon into fibroblasts and muscle cells. J Cell Biol (1990) 0.98
Fascin1 promotes cell migration of mature dendritic cells. J Immunol (2011) 0.95
Fascin1 is dispensable for mouse development but is favorable for neonatal survival. Cell Motil Cytoskeleton (2009) 0.95
A novel Rho-dependent pathway that drives interaction of fascin-1 with p-Lin-11/Isl-1/Mec-3 kinase (LIMK) 1/2 to promote fascin-1/actin binding and filopodia stability. BMC Biol (2012) 0.94
Actin binding proteins: their ups and downs in metastatic life. Cell Adh Migr (2013) 0.90
The interplay between the proteolytic, invasive, and adhesive domains of invadopodia and their roles in cancer invasion. Cell Adh Migr (2014) 0.83
Targeted inhibition of fascin function blocks tumour invasion and metastatic colonization. Nat Commun (2015) 0.81
Isolation and partial characterization of a 110-kD dimer actin-binding protein. J Cell Biol (1986) 0.81
Fascin-positive dendritic cells and fibroblastic reticulum cells build a framework of T-cell areas in lymph nodes. Virchows Arch (2003) 0.80
Fascin confers resistance to Listeria infection in dendritic cells. J Immunol (2013) 0.78
Fascin over expression is associated with dysplastic changes in sinonasal inverted papillomas: a study of 47 cases. Head Neck Pathol (2009) 0.78
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Ca2+-dependent myosin II activation is required for uropod retraction during neutrophil migration. J Cell Sci (2000) 2.19
Rho-kinase/ROCK is involved in cytokinesis through the phosphorylation of myosin light chain and not ezrin/radixin/moesin proteins at the cleavage furrow. Oncogene (2000) 2.08
Identification of an actin binding region and a protein kinase C phosphorylation site on human fascin. J Biol Chem (1997) 2.02
Differential expression of tropomyosin forms in the microfilaments isolated from normal and transformed rat cultured cells. J Biol Chem (1983) 1.99
Fascin, an actin-bundling protein, induces membrane protrusions and increases cell motility of epithelial cells. Mol Biol Cell (1998) 1.86
Differential modulation of actin-severing activity of gelsolin by multiple isoforms of cultured rat cell tropomyosin. Potentiation of protective ability of tropomyosins by 83-kDa nonmuscle caldesmon. J Biol Chem (1989) 1.65
Isolation and characterization of tropomyosin-containing microfilaments from cultured cells. J Biol Chem (1983) 1.61
Intracellular localization of the 55-kD actin-bundling protein in cultured cells: spatial relationships with actin, alpha-actinin, tropomyosin, and fimbrin. J Cell Biol (1986) 1.61
Phosphorylation of non-muscle caldesmon by p34cdc2 kinase during mitosis. Nature (1991) 1.58
Phosphorylation of human fascin inhibits its actin binding and bundling activities. J Biol Chem (1996) 1.57
Cell-matrix adhesions differentially regulate fascin phosphorylation. Mol Biol Cell (1999) 1.52
Dieldrin: degradation by soil microorganism. Science (1967) 1.47
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Role of the actin bundling protein fascin in growth cone morphogenesis: localization in filopodia and lamellipodia. Cell Motil Cytoskeleton (2001) 1.45
Fascin, a sensitive new marker for Reed-Sternberg cells of hodgkin's disease. Evidence for a dendritic or B cell derivation? Am J Pathol (1997) 1.39
Phenylmercuric acetate: metabolic conversion by microorganisms. Science (1971) 1.38
Cloning and sequencing of the para-type sodium channel gene from susceptible and kdr-resistant German cockroaches (Blattella germanica) and house fly (Musca domestica). Mol Gen Genet (1996) 1.36
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Purification and characterization of multiple isoforms of tropomyosin from rat cultured cells. J Biol Chem (1985) 1.32
Mitosis-specific phosphorylation causes 83K non-muscle caldesmon to dissociate from microfilaments. Nature (1990) 1.30
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Activation of myosin phosphatase targeting subunit by mitosis-specific phosphorylation. J Cell Biol (1999) 1.26
Small GTP-binding protein Rho stimulates the actomyosin system, leading to invasion of tumor cells. J Biol Chem (1998) 1.22
Circulating human dendritic cells differentially express high levels of a 55-kd actin-bundling protein. Am J Pathol (1996) 1.21
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Metabolic pathways utilized by Phanerochaete chrysosporium for degradation of the cyclodiene pesticide endosulfan. Appl Environ Microbiol (1996) 1.12
Localization of caldesmon and its dephosphorylation during cell division. J Cell Biol (1993) 1.12
Regulation of actin binding and actin bundling activities of fascin by caldesmon coupled with tropomyosin. J Biol Chem (1998) 1.10
Annealing of gelsolin-severed actin fragments by tropomyosin in the presence of Ca2+. Potentiation of the annealing process by caldesmon. J Biol Chem (1989) 1.10
Degradation of insecticides by a soil fungus, trichoderma viride. J Econ Entomol (1968) 1.08
Characterization of 83-kilodalton nonmuscle caldesmon from cultured rat cells: stimulation of actin binding of nonmuscle tropomyosin and periodic localization along microfilaments like tropomyosin. J Cell Biol (1988) 1.08
cDNA cloning and expression of the human homolog of the sea urchin fascin and Drosophila singed genes which encodes an actin-bundling protein. DNA Cell Biol (1994) 1.08
Specific inhibition of calcineurin by type II synthetic pyrethroid insecticides. Biochem Pharmacol (1992) 1.07
Tropomyosin-enriched and alpha-actinin-enriched microfilaments isolated from chicken embryo fibroblasts by monoclonal antibodies. J Cell Biol (1984) 1.07
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Studies on the bioaccumulation and microbial degradation of 2,3,7,8-tetrachlorodibenzo-p-dioxin. Environ Health Perspect (1973) 1.04
Potential role of the src gene product in inhibition of gap-junctional communication in NIH/3T3 cells. Proc Natl Acad Sci U S A (1985) 1.04
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2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-induced changes in glucose transporting activity in guinea pigs, mice, and rats in vivo and in vitro. J Biochem Toxicol (1994) 1.02
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Fate of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in a model aquatic environment. Arch Environ Contam Toxicol (1978) 1.01
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Structure of vimentin 10-nm filaments probed with a monoclonal antibody that recognizes a common antigenic determinant on vimentin and tropomyosin. Cold Spring Harb Symp Quant Biol (1982) 0.99
Mutant Caldesmon lacking cdc2 phosphorylation sites delays M-phase entry and inhibits cytokinesis. Mol Biol Cell (2001) 0.99
Microinjection of nonmuscle and smooth muscle caldesmon into fibroblasts and muscle cells. J Cell Biol (1990) 0.98
Alterations in fascin-expressing germinal center dendritic cells in neoplastic follicles of B-cell lymphomas. Mod Pathol (1998) 0.98
Rabbit serum hypertriglyceridemia after administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). J Toxicol Environ Health (1988) 0.97
Modulation of actin-bundling activity of 55-kDa protein by multiple isoforms of tropomyosin. J Biol Chem (1986) 0.97
Differential effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the "adipose- type" and "brain-type" glucose transporters in mice. Mol Pharmacol (1995) 0.96
Degradation of endrin, aldrin, and DDT by soil microorganisms. Appl Microbiol (1970) 0.96
Cytotoxic, mutagenic, and cell-cell communication inhibitory properties of DDT, lindane, and chlordane on Chinese hamster cells in vitro. Arch Environ Contam Toxicol (1983) 0.96
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Expression of the actin-bundling protein fascin in cultured human dendritic cells correlates with dendritic morphology and cell differentiation. J Invest Dermatol (2000) 0.96
2,3,7,8-Tetrachlorodibenzo-p-dioxin causes reduction of glucose transporting activities in the plasma membranes of adipose tissue and pancreas from the guinea pig. J Biol Chem (1992) 0.95
Increased ErbB-2 tyrosine kinase activity, MAPK phosphorylation, and cell proliferation in the prostate cancer cell line LNCaP following treatment by select pesticides. Toxicol Sci (2001) 0.95
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The primary structure of cytoplasmic initiator transfer ribonucleic acid from Torulopsis utilis. J Biochem (1979) 0.93
Mitosis-specific phosphorylation of myosin light chain kinase. J Biol Chem (1991) 0.93
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Regulation of glucose transport in the NIH 3T3 L1 preadipocyte cell line by TCDD. Environ Health Perspect (1994) 0.91
Monocyte chemoattractant protein-1 enhances expression of intercellular adhesion molecule-1 following ischemia-reperfusion of the liver in rats. Hepatology (1998) 0.91
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Activation of c-Neu tyrosine kinase by o,p'-DDT and beta-HCH in cell-free and intact cell preparations from MCF-7 human breast cancer cells. J Biochem Mol Toxicol (1998) 0.90
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Effects of in vivo-administered 2,3,7,8-tetrachlorodibenzo-p-dioxin on receptor binding of epidermal growth factor in the hepatic plasma membrane of rat, guinea pig, mouse, and hamster. Proc Natl Acad Sci U S A (1984) 0.88
Visualization of monoclonal antibody binding to tropomyosin on native smooth muscle thin filaments by electron microscopy. J Mol Biol (1982) 0.87
TCDD (2,3,7,8-tetrachlorodibenzo-P-dioxin) causes reduction in glucose uptake through glucose transporters on the plasma membrane of the guinea pig adipocyte. J Environ Sci Health B (1992) 0.87
Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on guinea pig heart muscle. Toxicol Appl Pharmacol (1987) 0.87
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2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced activation of a protein tyrosine kinase, pp60src, in murine hepatic cytosol using a cell-free system. Mol Pharmacol (1997) 0.86
DDT metabolized by microorganisms from Lake Michigan. Nature (1971) 0.86
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