Published in J Mol Biol on August 15, 1979
A system for shotgun DNA sequencing. Nucleic Acids Res (1981) 52.99
Novel bacteriophage lambda cloning vector. Proc Natl Acad Sci U S A (1980) 8.97
Expression of bacterial genes in plant cells. Proc Natl Acad Sci U S A (1983) 8.70
pUR222, a vector for cloning and rapid chemical sequencing of DNA. Nucleic Acids Res (1981) 6.55
Fine-structure analysis of the DNA sequence requirements for autonomous replication of Saccharomyces cerevisiae plasmids. Mol Cell Biol (1986) 5.22
Short direct repeats flank the T-DNA on a nopaline Ti plasmid. Proc Natl Acad Sci U S A (1982) 4.78
Specific amino acid substitutions in bacterioopsin: Replacement of a restriction fragment in the structural gene by synthetic DNA fragments containing altered codons. Proc Natl Acad Sci U S A (1984) 3.67
pUR 250 allows rapid chemical sequencing of both DNA strands of its inserts. Nucleic Acids Res (1982) 3.40
Molecular cloning of TOL genes xylB and xylE in Escherichia coli. J Bacteriol (1981) 3.08
Cloning of antibiotic resistance and nutritional genes in streptomycetes. J Bacteriol (1982) 3.06
Cloning and restriction mapping of the alkaline phosphatase structural gene (phoA) of Escherichia coli and generation of deletion mutants in vitro. J Bacteriol (1981) 2.88
Control of pT181 replication I. The pT181 copy control function acts by inhibiting the synthesis of a replication protein. EMBO J (1984) 2.87
Molecular cloning and expression of Bacillus licheniformis beta-lactamase gene in Escherichia coli and Bacillus subtilis. J Bacteriol (1981) 2.75
Macromolecular crowding allows blunt-end ligation by DNA ligases from rat liver or Escherichia coli. Proc Natl Acad Sci U S A (1983) 2.41
Location of the active site for enzyme-adenylate formation in DNA ligases. Proc Natl Acad Sci U S A (1991) 2.32
Multiple differences between the nucleic acid sequences of the IgG2aa and IgG2ab alleles of the mouse. Proc Natl Acad Sci U S A (1981) 2.23
Hepatitis B virus core antigen: synthesis in Escherichia coli and application in diagnosis. Proc Natl Acad Sci U S A (1982) 2.19
The nucleotide sequence of the uvrD gene of E. coli. Nucleic Acids Res (1984) 2.14
Molecular cloning of staphylococcal enterotoxin B gene in Escherichia coli and Staphylococcus aureus. Proc Natl Acad Sci U S A (1985) 2.13
The nucleotide sequence of the DNA ligase gene (CDC9) from Saccharomyces cerevisiae: a gene which is cell-cycle regulated and induced in response to DNA damage. Nucleic Acids Res (1985) 2.13
Nucleotide sequence at the end of the gene for the RNA polymerase beta' subunit (rpoC). Nucleic Acids Res (1981) 1.95
Organization of the lexA gene of Escherichia coli and nucleotide sequence of the regulatory region. Nucleic Acids Res (1981) 1.90
Coding sequence for the pT181 repC product: a plasmid-coded protein uniquely required for replication. Proc Natl Acad Sci U S A (1982) 1.89
Nucleotide sequence of the tmr locus of Agrobacterium tumefaciens pTi T37 T-DNA. Nucleic Acids Res (1984) 1.62
Highlights of the DNA cutters: a short history of the restriction enzymes. Nucleic Acids Res (2013) 1.60
Structural analysis of plasmid pSN2 in Staphylococcus aureus: no involvement in enterotoxin B production. J Bacteriol (1982) 1.57
The construction of cosmid libraries of eukaryotic DNA using the Homer series of vectors. Nucleic Acids Res (1982) 1.47
Genes 55, alpha gt, 47 and 46 of bacteriophage T4: the genomic organization as deduced by sequence analysis. EMBO J (1985) 1.46
Primary structure of the replication initiation protein of plasmid R6K. Proc Natl Acad Sci U S A (1982) 1.40
A sequence-specific endonuclease (Xmn I) from Xanthomonas manihotis. Nucleic Acids Res (1980) 1.38
Regulation of inter- and intramolecular ligation with T4 DNA ligase in the presence of polyethylene glycol. Nucleic Acids Res (1986) 1.29
Characterization of the tetracycline resistance gene of plasmid pT181 of Staphylococcus aureus. J Bacteriol (1988) 1.28
Sequence and cloning of bacteriophage T4 gene 63 encoding RNA ligase and tail fibre attachment activities. EMBO J (1984) 1.27
T4 polynucleotide kinase; cloning of the gene (pseT) and amplification of its product. EMBO J (1985) 1.26
Initiation signals for complementary strand DNA synthesis on single-stranded plasmid DNA. Nucleic Acids Res (1983) 1.26
Nucleotide sequence of a type II DNA topoisomerase gene. Bacteriophage T4 gene 39. Nucleic Acids Res (1986) 1.25
Influence of monovalent cations on the activity of T4 DNA ligase in the presence of polyethylene glycol. Nucleic Acids Res (1985) 1.24
Molecular cloning of the spo0B sporulation locus in bacteriophage lambda. J Bacteriol (1982) 1.23
Type II restriction endonucleases--a historical perspective and more. Nucleic Acids Res (2014) 1.22
Production of immunologically active surface antigens of hepatitis B virus by Escherichia coli. Proc Natl Acad Sci U S A (1981) 1.16
Initiation and termination of the bacteriophage phi X174 rolling circle DNA replication in vivo: packaging of plasmid single-stranded DNA into bacteriophage phi X174 coats. Nucleic Acids Res (1982) 1.13
T4-induced alpha- and beta-glucosyltransferase: cloning of the genes and a comparison of their products based on sequencing data. Nucleic Acids Res (1985) 1.13
Transcription of sea urchin histone genes in Escherichia coli. Nucleic Acids Res (1981) 1.10
Primary structure and genetic organization of phage T4 DNA ligase. Nucleic Acids Res (1983) 1.10
High level synthesis in Escherichia coli of the Bacillus subtilis phage phi 29 proteins p3 and p4 under the control of phage lambda PL promoter. Nucleic Acids Res (1982) 1.10
Temperature dependence of the joining by T4 DNA ligase of termini produced by type II restriction endonucleases. Nucleic Acids Res (1981) 1.05
Construction of bacterial plasmids containing sequences complementary to chicken alpha-tropomyosin mRNA. Nucleic Acids Res (1981) 0.92
Arrangement of the central pseudoknot region of 16S rRNA in the 30S ribosomal subunit determined by site-directed 4-thiouridine crosslinking. RNA (2001) 0.91
Anthramycin inhibition of restriction endonuclease cleavage and its use as a reversible blocking agent in DNA constructions. Nucleic Acids Res (1981) 0.89
A comparison of DNA cleavage by the restriction enzymes SalPI and PstI. Nucleic Acids Res (1980) 0.87
Cloned bacteriophage phi X174 DNA sequence interferes with synthesis of the complementary strand of infecting bacteriophage phi X174. J Virol (1982) 0.87
Cloning of bacteriophage fd gene 2 and construction of a plasmid dependent on fd gene 2 protein. Proc Natl Acad Sci U S A (1981) 0.87
Double-stranded cleavage of pBR322 by a diiron complex via a "hydrolytic" mechanism. Proc Natl Acad Sci U S A (1994) 0.87
Regions of incompatibility in single-stranded DNA bacteriophages phi X174 and G4. J Virol (1984) 0.82
Specific and reversible inhibition of the blunt end joining activity of the T4 DNA ligase. Nucleic Acids Res (1981) 0.81
Critical Factors Affecting the Success of Cloning, Expression, and Mass Production of Enzymes by Recombinant E. coli. ISRN Biotechnol (2012) 0.79
Genetic transformation of Streptococcus pneumoniae by DNA cloned into the single-stranded bacteriophage f1. J Bacteriol (1983) 0.78
Genome Analysis of a Novel Broad Host Range Proteobacteria Phage Isolated from a Bioreactor Treating Industrial Wastewater. Genes (Basel) (2017) 0.75
A specific endonuclease from Arthrobacter luteus. J Mol Biol (1976) 25.89
Lambdoid phages that simplify the recovery of in vitro recombinants. Mol Gen Genet (1977) 16.76
The outbreak of West Nile virus infection in the New York City area in 1999. N Engl J Med (2001) 11.48
Hepatitis B virus genes and their expression in E. coli. Nature (1979) 10.83
Phage lambda receptor chromosomes for DNA fragments made with restriction endonuclease III of Haemophilus influenzae and restriction endonuclease I of Escherichia coli. J Mol Biol (1975) 10.57
Sequence diversity among related genes for recognition of specific targets in DNA molecules. J Mol Biol (1983) 10.16
Metabolism of benzoate and the methylbenzoates by Pseudomonas putida (arvilla) mt-2: evidence for the existence of a TOL plasmid. J Bacteriol (1974) 9.37
Packaging recombinant DNA molecules into bacteriophage particles in vitro. Proc Natl Acad Sci U S A (1977) 7.42
Manipulation of restriction targets in phage lambda to form receptor chromosomes for DNA fragments. Nature (1974) 7.22
The construction in vitro of transducing derivatives of phage lambda. Mol Gen Genet (1976) 6.50
Recognition sequence of restriction endonuclease III from Hemophilus influenzae. J Mol Biol (1975) 6.23
The metabolism of benzoate and methylbenzoates via the meta-cleavage pathway by Pseudomonas arvilla mt-2. Eur J Biochem (1972) 5.98
Restriction and modification systems. Annu Rev Genet (1991) 5.91
McrA and McrB restriction phenotypes of some E. coli strains and implications for gene cloning. Nucleic Acids Res (1988) 5.76
Recognition sequence of a restriction enzyme. Nat New Biol (1973) 5.14
The evolution of gene clusters and genetic circularity in microorganisms. Genetics (1966) 4.88
Nucleotide sequence analysis with polynucleotide kinase and nucleotide "mapping" methods. 5'-Terminal sequences of deoxyribonucleic acid from bacteriophages lambda and 424. Biochem J (1973) 4.86
Infection of humans and horses by a newly described morbillivirus. Med J Aust (1995) 4.68
The metabolic divergence in the meta cleavage of catechols by Pseudomonas putida NCIB 10015. Physiological significance and evolutionary implications. Eur J Biochem (1972) 4.16
Inhibitory control in young children and its role in emerging internalization. Child Dev (1996) 3.60
Inhibitory control as a contributor to conscience in childhood: from toddler to early school age. Child Dev (1997) 3.16
Expression in Escherichia coli of hepatitis B virus DNA sequences cloned in plasmid pBR322. Nature (1979) 3.03
Validation of the RTOG recursive partitioning analysis (RPA) classification for brain metastases. Int J Radiat Oncol Biol Phys (2000) 3.00
Platelet-derived growth factor promotes division and motility and inhibits premature differentiation of the oligodendrocyte/type-2 astrocyte progenitor cell. Nature (1988) 2.99
Nucleotide 'maps' of digests of deoxyribonucleic acid. Biochem J (1970) 2.95
Infectivity in mouse fibroblasts of polyoma DNA integrated into plasmid pBR322 or lambdoid phage DNA. Nature (1979) 2.92
A specific endonuclease from Haemophilus haemolyticus. J Mol Biol (1976) 2.92
Dental practitioners and ill health retirement: causes, outcomes and re-employment. Br Dent J (2010) 2.83
Restriction and modification in B. subtilis. Purification and general properties of a restriction endonuclease from strain R. Mol Gen Genet (1975) 2.79
Role of catechol and the methylcatechols as inducers of aromatic metabolism in Pseudomonas putida. J Bacteriol (1974) 2.78
Expression of the hepatitis B virus surface, core and E antigen genes by stable rat and mouse cell lines. J Mol Biol (1982) 2.75
Enhanced recovery and restriction mapping of DNA fragments cloned in a new lambda vector. Nucleic Acids Res (1988) 2.71
The hsd (host specificity) genes of E. coli K 12. Mol Gen Genet (1980) 2.63
Isolation and characterization of a lambdapolA transducing phage. Proc Natl Acad Sci U S A (1977) 2.55
Determinants of diagnostic investigation sensitivities across the clinical spectrum of sporadic Creutzfeldt-Jakob disease. Brain (2006) 2.54
Physical characterisation of the "Rac prophage" in E. coli K12. Mol Gen Genet (1979) 2.49
Suppression of malignancy and differentiation in melanotic melanoma cells. Proc Natl Acad Sci U S A (1970) 2.44
Convergent transcription in bacteriophage lambda: interference with gene expression. J Mol Biol (1979) 2.32
Dietary calcium, physical activity, and risk of hip fracture: a prospective study. BMJ (1989) 2.24
Restriction and modification in B. subtilis. Nucleotide sequence recognised by restriction endonuclease R. Bsu R from strain R. Mol Gen Genet (1975) 2.20
Hepatitis B virus core antigen: synthesis in Escherichia coli and application in diagnosis. Proc Natl Acad Sci U S A (1982) 2.19
Molecular cloning of the T4 genome; organization and expression of the frd--DNA ligase region. Mol Gen Genet (1980) 2.18
Nucleoside triphosphate-dependent restriction enzymes. Nucleic Acids Res (2001) 2.12
Muscle weakness in women occurs at an earlier age than in men, but strength is preserved by hormone replacement therapy. Clin Sci (Lond) (1993) 2.12
The conversion of hepatitis B core antigen synthesized in E coli into e antigen. J Med Virol (1981) 2.11
Molecular cloning of fragments of bacteriophage T4 DNA. Mol Gen Genet (1977) 2.10
Molecular cloning of the DNA ligase gene from bacteriophage T4. I. Characterisation of the recombinants. J Mol Biol (1979) 2.06
Organization and sequence of the hsd genes of Escherichia coli K-12. J Mol Biol (1987) 1.95
Chimeric brains generated by intraventricular transplantation of fetal human brain cells into embryonic rats. Nat Biotechnol (1998) 1.95
The 3'-terminal nucleotide sequences of bacteriophage lambda DNA. Proc Natl Acad Sci U S A (1973) 1.92
Integration of hepatitis B virus DNA: evidence for integration in the single-stranded gap. Cell (1983) 1.87
Microbial metabolism of aryl sulphonates a re-assessment of colorimetric methods for the determination of sulphite and their use in measuring desulphonation of aryl and alkylbenzene sulphonates. Antonie Van Leeuwenhoek (1975) 1.87
DNA targets for the Escherichia coli K restriction system analysed genetically in recombinants between phages phi80 and lambda. Mol Gen Genet (1973) 1.84
Genetic recombination can generate altered restriction specificity. Proc Natl Acad Sci U S A (1984) 1.79
Reassortment of DNA recognition domains and the evolution of new specificities. Mol Microbiol (1987) 1.76
Updated results of the phase III Radiation Therapy Oncology Group (RTOG) trial 85-31 evaluating the potential benefit of androgen suppression following standard radiation therapy for unfavorable prognosis carcinoma of the prostate. Int J Radiat Oncol Biol Phys (2001) 1.76
Terminal nucleotide sequences of DNA from temperate coliphages. Nat New Biol (1973) 1.76
Structure and nucleotide sequence of the terminal regions of adeno-associated virus DNA. Virology (1977) 1.75
Dental practitioners and ill health retirement: a qualitative investigation into the causes and effects. Br Dent J (2010) 1.74
Yeast H3 and H4 histone messenger RNAs are transcribed from two non-allelic gene sets. J Mol Biol (1983) 1.72
Purified astrocytes promote the in vitro division of a bipotential glial progenitor cell. EMBO J (1984) 1.69
Restriction of bacteriophage lambda by Escherichia coli K. J Mol Biol (1973) 1.68
Prophylactic cranial irradiation for lung cancer patients at high risk for development of cerebral metastasis: results of a prospective randomized trial conducted by the Radiation Therapy Oncology Group. Int J Radiat Oncol Biol Phys (1991) 1.65
Sequence evolution of the hypervariable region in the putative envelope region E2/NS1 of hepatitis C virus is correlated with specific humoral immune responses. J Virol (1995) 1.63
Structural homologies among type I restriction-modification systems. EMBO J (1982) 1.62
Purification and characterization of the methyltransferase from the type 1 restriction and modification system of Escherichia coli K12. J Biol Chem (1993) 1.62
Isolation and characterization of two sequence-specific endonucleases from Anabaena variabilis. Biochem J (1976) 1.62
Immunogenicity of peptide fusions to hepatitis B virus core antigen. Proc Natl Acad Sci U S A (1989) 1.57
Conservation of complex DNA recognition domains between families of restriction enzymes. Cell (1989) 1.57
Two DNA recognition domains of the specificity polypeptides of a family of type I restriction enzymes. Proc Natl Acad Sci U S A (1986) 1.56
Hepatitis B virus antigens made in microbial cells immunise against viral infection. EMBO J (1984) 1.54
The diversity of alleles at the hsd locus in natural populations of Escherichia coli. Genetics (1995) 1.53
The configuration of the 1,2-dihydroxy-1,2-dihydronaphthalene formed in the bacterial metabolism of naphthalene. Biochim Biophys Acta (1971) 1.51
Experiences and expectations of refugee doctors: Qualitative study. Br J Psychiatry (2006) 1.49
ACUTE PANCREATIC NECROSIS : (A review of twenty cases). Can Med Assoc J (1934) 1.48
On the structure and operation of type I DNA restriction enzymes. J Mol Biol (1999) 1.48
Conservation of organization in the specificity polypeptides of two families of type I restriction enzymes. J Mol Biol (1989) 1.48
A mutational analysis of the two motifs common to adenine methyltransferases. EMBO J (1994) 1.46
Oestrogen status in relation to the early training responses in human thumb adductor muscles. Acta Physiol (Oxf) (2006) 1.46
Clean intermittent self-catheterisation in the management of adult lower urinary tract dysfunction. Br J Urol (1984) 1.45
EcoA and EcoE: alternatives to the EcoK family of type I restriction and modification systems of Escherichia coli. J Mol Biol (1985) 1.44
Social and gender variation in the prevalence, presentation and general practitioner provisional diagnosis of chest pain. J Epidemiol Community Health (2000) 1.44
A specific endonuclease from Brevibacterium albidum. J Mol Biol (1977) 1.43
IL-12, as an adjuvant, promotes a T helper 1 cell, but does not suppress a T helper 2 cell recall response. J Immunol (1996) 1.42
Inadequacies in the Mental Health Act, 1983 in relation to mentally disordered remand prisoners. Med Sci Law (1997) 1.39
On the nature of sbcA mutations in E. coli K 12. Mol Gen Genet (1980) 1.39
Metabolism of naphthalene, 2-methylnaphthalene, salicylate, and benzoate by Pseudomonas PG: regulation of tangential pathways. J Bacteriol (1975) 1.36
Maternal reports of conscience development and temperament in young children. Child Dev (1994) 1.36
Bowel cleansing for colonoscopy: prospective randomized assessment of efficacy and of induced mucosal abnormality with three preparation agents. Endoscopy (2011) 1.35
Roles of selection and recombination in the evolution of type I restriction-modification systems in enterobacteria. Proc Natl Acad Sci U S A (1992) 1.34