Published in Nucleic Acids Res on April 24, 1982
Efficient cloning of genes of Neurospora crassa. Proc Natl Acad Sci U S A (1986) 6.08
The physical map and organisation of the mitochondrial genome from the fertile cytoplasm of maize. Nucleic Acids Res (1984) 4.23
Cosmid vectors for rapid genomic walking, restriction mapping, and gene transfer. Proc Natl Acad Sci U S A (1987) 4.13
A recB recC sbcB recJ host prevents recA-independent deletions in recombinant cosmid DNA propagated in Escherichia coli. J Bacteriol (1989) 1.90
Identification of an Epstein-Barr virus-coded thymidine kinase. EMBO J (1986) 1.31
Cosmid clones derived from both euchromatic and heterochromatic regions of the human Y chromosome. EMBO J (1984) 1.21
Functional analysis of a simian virus 40 super T-antigen. J Virol (1982) 1.11
Widely differing degrees of sequence conservation of the two types of rDNA insertion within the melanogaster species sub-group of Drosophila. EMBO J (1983) 0.97
The organization of the tadpole and adult alpha globin genes of Xenopus laevis. Nucleic Acids Res (1982) 0.94
A 78-kilobase region of mouse chromosome 3 contains salivary and pancreatic amylase genes and a pseudogene. Proc Natl Acad Sci U S A (1985) 0.94
Two-level factorial screening for influence of temperature, pH, and aeration on production of Serratia marcescens nuclease. Appl Environ Microbiol (1987) 0.85
Transcription of a cloned rainbow trout protamine gene is accurately initiated following transfection into HeLa cells but the majority of the transcripts fail to polyadenylate at the correct site. Nucleic Acids Res (1985) 0.77
Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol (1975) 503.08
Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I. J Mol Biol (1977) 205.11
Construction and characterization of new cloning vehicles. II. A multipurpose cloning system. Gene (1977) 114.87
Complete nucleotide sequence of the Escherichia coli plasmid pBR322. Cold Spring Harb Symp Quant Biol (1979) 43.48
Rapid and efficient cosmid cloning. Nucleic Acids Res (1981) 40.13
The isolation of structural genes from libraries of eucaryotic DNA. Cell (1978) 37.13
SV40-transformed simian cells support the replication of early SV40 mutants. Cell (1981) 34.67
A system for mapping DNA sequences in the chromosomes of Drosophila melanogaster. Cell (1974) 27.33
In vivo sequence requirements of the SV40 early promotor region. Nature (1981) 25.00
A small cosmid for efficient cloning of large DNA fragments. Gene (1980) 22.61
Expression of a beta-globin gene is enhanced by remote SV40 DNA sequences. Cell (1981) 20.72
Charon phages: safer derivatives of bacteriophage lambda for DNA cloning. Science (1977) 20.27
Trans-complementable copy-number mutants of plasmid ColE1. Nature (1980) 17.11
Plasmid screening at high colony density. Gene (1980) 16.47
Cosmids: a type of plasmid gene-cloning vector that is packageable in vitro in bacteriophage lambda heads. Proc Natl Acad Sci U S A (1978) 16.33
Enhanced autoradiographic detection of 32P and 125I using intensifying screens and hypersensitized film. FEBS Lett (1977) 15.45
Inhibition of SV40 replication in simian cells by specific pBR322 DNA sequences. Nature (1981) 13.89
A physical map of the DNA regions flanking the rabbit beta-globin gene. Cell (1977) 12.96
Identification of DNA sequences required for transcription of the human alpha 1-globin gene in a new SV40 host-vector system. Cell (1981) 9.81
The chromosomal arrangement of human alpha-like globin genes: sequence homology and alpha-globin gene deletions. Cell (1980) 9.13
Construction and analysis of viable deletion mutants of simian virus 40. J Virol (1976) 9.11
Packaging recombinant DNA molecules into bacteriophage particles in vitro. Proc Natl Acad Sci U S A (1977) 7.42
End labeling of enzymatically decapped mRNA. Nucleic Acids Res (1977) 6.58
Transformation in Escherichia coli: cryogenic preservation of competent cells. J Bacteriol (1977) 6.11
Isolation of beta-globin-related genes from a human cosmid library. Gene (1981) 5.97
Molecular cloning of the DNA ligase gene from bacteriophage T4. II. Amplification and preparation of the gene product. J Mol Biol (1979) 5.86
Factors affecting the transformation of Escherichia coli strain chi1776 by pBR322 plasmid DNA. Gene (1978) 5.15
DNA sequences necessary for transcription of the rabbit beta-globin gene in vivo. Nature (1982) 4.97
A new high-capacity cosmid vector and its use. Gene (1980) 4.72
Structure and genomic organization of the mouse dihydrofolate reductase gene. Cell (1980) 4.25
Restriction and modification of a self-complementary octanucleotide containing the EcoRI substrate. J Mol Biol (1975) 4.21
Plasmids useable as gene-cloning vectors in an in vitro packaging by coliphage lambda: "cosmids". Gene (1978) 3.66
Beta + thalassemia: aberrant splicing results from a single point mutation in an intron. Cell (1981) 3.51
Cloning of human satellite III DNA: different components are on different chromosomes. Nucleic Acids Res (1979) 3.01
Infectivity in mouse fibroblasts of polyoma DNA integrated into plasmid pBR322 or lambdoid phage DNA. Nature (1979) 2.92
Molecular cloning of the complete Epstein-Barr virus genome as a set of overlapping restriction endonuclease fragments. Nucleic Acids Res (1981) 2.83
Physical characterisation of the "Rac prophage" in E. coli K12. Mol Gen Genet (1979) 2.49
Regulation of ribosomal RNA gene multiplicity in Drosophila melanogaster. Genetics (1973) 2.25
Structure of the pro alpha 2 (I) collagen gene. Nature (1981) 2.16
The integrated forms of the S1 and S2 DNA elements of maize male sterile mitochondrial DNA are flanked by a large repeated sequence. Nucleic Acids Res (1981) 2.07
Cloning and characterization of the integrated viral DNA from three lines of SV40-transformed mouse cells. Cell (1981) 1.72
A DNA segment from D. melanogaster which contains five tandemly repeating units homologous to the major rDNA insertion. Cell (1980) 1.59
Fate of viral DNA in nonpermissive cells infected with simian virus 40. Proc Natl Acad Sci U S A (1981) 1.51
Isolation and characterization of the complete chicken beta-globin gene region: frequent deletion of the adult beta-globin genes in lambda. Nucleic Acids Res (1981) 1.20
Mapping of restriction sites in the attachment site region of bacteriophage lambda. Mol Gen Genet (1977) 1.12
DNA organisation in the chicken lysozyme gene region. Nucleic Acids Res (1981) 1.01
Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I. J Mol Biol (1977) 205.11
Biochemical method for mapping mutational alterations in DNA with S1 nuclease: the location of deletions and temperature-sensitive mutations in simian virus 40. Proc Natl Acad Sci U S A (1975) 7.57
Trans-acting protein factors and the regulation of eukaryotic transcription: lessons from studies on DNA tumor viruses. Genes Dev (1988) 7.52
A protein trap strategy to detect GFP-tagged proteins expressed from their endogenous loci in Drosophila. Proc Natl Acad Sci U S A (2001) 6.67
Negative regulation of viral enhancers in undifferentiated embryonic stem cells. Cell (1985) 5.88
McrA and McrB restriction phenotypes of some E. coli strains and implications for gene cloning. Nucleic Acids Res (1988) 5.76
A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo. Nature (1990) 4.69
Know your neighbors: three phenotypes in null mutants of the myogenic bHLH gene MRF4. Cell (1996) 4.55
Prion protein biology. Cell (1998) 4.20
Activation of mouse genes in transformed cells. Cell (1983) 3.85
A transmembrane form of the prion protein in neurodegenerative disease. Science (1998) 3.76
Transcription factor AP-2 is expressed in neural crest cell lineages during mouse embryogenesis. Genes Dev (1991) 3.46
Scrapie-infected murine neuroblastoma cells produce protease-resistant prion proteins. J Virol (1988) 3.37
The regulation of myogenin gene expression during the embryonic development of the mouse. Genes Dev (1993) 3.15
Role of inscuteable in orienting asymmetric cell divisions in Drosophila. Nature (1996) 2.87
Accuracy of surface landmark identification for cannula cricothyroidotomy. Anaesthesia (2010) 2.83
Analysis of partner of inscuteable, a novel player of Drosophila asymmetric divisions, reveals two distinct steps in inscuteable apical localization. Cell (2000) 2.64
Strain-specified relative conformational stability of the scrapie prion protein. Protein Sci (2001) 2.60
Isolation and characterization of an alphoid centromeric repeat family from the human Y chromosome. J Mol Biol (1985) 2.39
Multiple spatially specific enhancers are required to reconstruct the pattern of Hox-2.6 gene expression. Genes Dev (1991) 2.20
The murine H19 gene is activated during embryonic stem cell differentiation in vitro and at the time of implantation in the developing embryo. Development (1991) 2.17
Gene duplication in experimental enzyme evolution. Nature (1974) 2.16
Activation of a Qa/Tla class I major histocompatibility antigen gene is a general feature of oncogenesis in the mouse. Nature (1984) 2.13
Molecular analysis of the Adh region of the genome of Drosophila melanogaster. J Mol Biol (1985) 1.99
An adenovirus E1A-like transcription factor is regulated during the differentiation of murine embryonal carcinoma stem cells. Cell (1987) 1.96
Transcripts regulated during normal embryonic development and oncogenic transformation share a repetitive element. Cell (1983) 1.94
The EAST protein of drosophila controls an expandable nuclear endoskeleton. Nat Cell Biol (2000) 1.89
A role for the TATA-box-binding protein component of the transcription factor IID complex as a general RNA polymerase III transcription factor. Proc Natl Acad Sci U S A (1992) 1.85
A dominant inhibitory version of the small GTP-binding protein Rac disrupts cytoskeletal structures and inhibits developmental cell shape changes in Drosophila. Development (1995) 1.83
Selective neuronal targeting in prion disease. Neuron (1997) 1.82
A fragment of the SV40 large T-antigen gene transforms. Nature (1982) 1.82
Regulation of RNA polymerase III transcription in response to F9 embryonal carcinoma stem cell differentiation. Cell (1989) 1.81
Two Drosophila receptor-like tyrosine phosphatase genes are expressed in a subset of developing axons and pioneer neurons in the embryonic CNS. Cell (1991) 1.81
Nramp defines a family of membrane proteins. Proc Natl Acad Sci U S A (1995) 1.78
Elimination of prions by branched polyamines and implications for therapeutics. Proc Natl Acad Sci U S A (1999) 1.73
Cloning and characterization of the integrated viral DNA from three lines of SV40-transformed mouse cells. Cell (1981) 1.72
Identification of two prion protein regions that modify scrapie incubation time. J Virol (2001) 1.63
A BAC transgenic analysis of the Mrf4/Myf5 locus reveals interdigitated elements that control activation and maintenance of gene expression during muscle development. Development (2001) 1.54
Mutation of the Adh gene of Drosophila melanogaster containing an internal tandem duplication. J Mol Biol (1985) 1.54
Regulatory elements involved in the tissue-specific expression of the yellow gene of Drosophila. Mol Gen Genet (1989) 1.54
Genetic control of phosphate-metabolizing enzymes in Neurospora crassa: relationships among regulatory mutations. Genetics (1975) 1.53
Inscuteable and numb mediate asymmetric muscle progenitor cell divisions during Drosophila myogenesis. Genes Dev (1998) 1.53
Fate of viral DNA in nonpermissive cells infected with simian virus 40. Proc Natl Acad Sci U S A (1981) 1.51
Mox2 is a component of the genetic hierarchy controlling limb muscle development. Nature (1999) 1.50
Does simian virus 40 DNA integrate into cellular DNA during productive infection? J Virol (1978) 1.48
Inscuteable and Staufen mediate asymmetric localization and segregation of prospero RNA during Drosophila neuroblast cell divisions. Cell (1997) 1.48
Cytoplasmic dynein (ddlc1) mutations cause morphogenetic defects and apoptotic cell death in Drosophila melanogaster. Mol Cell Biol (1996) 1.43
Ribitol dehydrogenase from Klebsiella aerogenes. Purification and subunit structure. Biochem J (1974) 1.39
Mapping of mutational alterations in DNA with S1 nuclease: the location of deletions, insertions and temperature-sensitive mutations in SV40. Cold Spring Harb Symp Quant Biol (1975) 1.39
Participation of small GTPases in dorsal closure of the Drosophila embryo: distinct roles for Rho subfamily proteins in epithelial morphogenesis. J Cell Sci (1999) 1.37
Drosophila rolling pebbles: a multidomain protein required for myoblast fusion that recruits D-Titin in response to the myoblast attractant Dumbfounded. Dev Cell (2001) 1.36
Branched polyamines cure prion-infected neuroblastoma cells. J Virol (2001) 1.32
Genetic control of phosphorus assimilation in Neurospora crassa: dose-dependent dominance and recessiveness in constitutive mutants. Genetics (1979) 1.31
Regulation of RNA polymerase III transcription in response to Simian virus 40 transformation. EMBO J (1990) 1.31
Hedgehog signalling is required for maintenance of myf5 and myoD expression and timely terminal differentiation in zebrafish adaxial myogenesis. Dev Biol (2001) 1.28
A family of snail-related zinc finger proteins regulates two distinct and parallel mechanisms that mediate Drosophila neuroblast asymmetric divisions. EMBO J (2001) 1.26
malvolio, the Drosophila homologue of mouse NRAMP-1 (Bcg), is expressed in macrophages and in the nervous system and is required for normal taste behaviour. EMBO J (1995) 1.25
Genetics of prions. Annu Rev Genet (1997) 1.25
Spontaneous excision of a large composite transposable element of Drosophila melanogaster. Nature (1985) 1.23
Derivatives of Moloney murine sarcoma virus capable of being transcribed in embryonal carcinoma stem cells have gained a functional Sp1 binding site. J Virol (1991) 1.23
Cloning vectors derived from animal viruses. J Gen Virol (1983) 1.22
The expression of Myf5 in the developing mouse embryo is controlled by discrete and dispersed enhancers specific for particular populations of skeletal muscle precursors. Development (2000) 1.22
cdc2 links the Drosophila cell cycle and asymmetric division machineries. Nature (2001) 1.22
Cosmid clones derived from both euchromatic and heterochromatic regions of the human Y chromosome. EMBO J (1984) 1.21
Structure and synthesis of a simian virus 40 super T-antigen. J Virol (1982) 1.21
Masquerade: a novel secreted serine protease-like molecule is required for somatic muscle attachment in the Drosophila embryo. Genes Dev (1995) 1.21
T antigens of SV40-transformed cells. Cold Spring Harb Symp Quant Biol (1980) 1.20
Receptor tyrosine phosphatases regulate axon guidance across the midline of the Drosophila embryo. Development (2000) 1.19
Metabolism of ricinine in the castor plant. Plant Physiol (1965) 1.18
The embryonal carcinoma stem cell Ela-like activity involves a differentiation-regulated transcription factor. Nucleic Acids Res (1990) 1.16
Binary sibling neuronal cell fate decisions in the Drosophila embryonic central nervous system are nonstochastic and require inscuteable-mediated asymmetry of ganglion mother cells. Genes Dev (1998) 1.16
Construction of intergeneric hybrids using bacteriophage P1CM: transfer of the Klebsiella aerogenes ribitol dehydrogenase gene to Escherichia coli. J Bacteriol (1976) 1.15
Identification and characterisation of a developmentally regulated mammalian gene that utilises -1 programmed ribosomal frameshifting. Nucleic Acids Res (2001) 1.12
A comparison of wild-type and mutant ribitol dehydrogenases from Klebsiella aerogenes. Biochem J (1974) 1.12
Expression and function of Pax 1 during development of the pectoral girdle. Development (1994) 1.11
Functional analysis of a simian virus 40 super T-antigen. J Virol (1982) 1.11
Regional localization of 3 Y-derived sequences on the human X and Y chromosomes. Ann Hum Genet (1984) 1.09
Dcdc42 acts in TGF-beta signaling during Drosophila morphogenesis: distinct roles for the Drac1/JNK and Dcdc42/TGF-beta cascades in cytoskeletal regulation. J Cell Sci (1999) 1.08
On the functional overlap between two Drosophila POU homeo domain genes and the cell fate specification of a CNS neural precursor. Genes Dev (1995) 1.06
The structure and expression of the preproenkephalin gene. Nucleic Acids Res (1982) 1.06
The molecular analyses of an antimorphic mutation of Drosophila melanogaster, Scutoid. Genetics (1988) 1.06
The role of a Drosophila POU homeo domain gene in the specification of neural precursor cell identity in the developing embryonic central nervous system. Genes Dev (1993) 1.04
Molecular and genetic characterization of SLC1, a putative Saccharomyces cerevisiae homolog of the metazoan cytoplasmic dynein light chain 1. Mol Gen Genet (1996) 1.01
Structure and expression of the rat epididymal secretory protein I gene. An androgen-regulated member of the lipocalin superfamily with a rare splice donor site. Biochem J (1992) 0.99
Two closely linked Drosophila POU domain genes are expressed in neuroblasts and sensory elements. Proc Natl Acad Sci U S A (1991) 0.99
SV40 and polyoma viruses: their analysis by deoxyribonucleic acid recombination in vitro and their use as vectors in eukaryotic systems. Biochem Soc Symp (1979) 0.99
Expression of the L14 lectin during mouse embryogenesis suggests multiple roles during pre- and post-implantation development. Development (1992) 0.98
Effect of passage in culture on a clone of BALB/c 3T3 cells transformed by simian virus 40. J Virol (1976) 0.97
The Drosophila bifocal gene encodes a novel protein which colocalizes with actin and is necessary for photoreceptor morphogenesis. Mol Cell Biol (1997) 0.97
Transcripts from an aberrantly re-arranged human T-cell receptor beta-chain gene. EMBO J (1985) 0.96
Dandy-Walker variant: prenatal sonographic features and clinical outcome. Radiology (1992) 0.96
The Drosophila l(2)35Ba/nocA gene encodes a putative Zn finger protein involved in the development of the embryonic brain and the adult ocellar structures. Mol Cell Biol (1994) 0.95
Apical secretion and association of the Drosophila yellow gene product with developing larval cuticle structures during embryogenesis. Mol Gen Genet (1992) 0.95
Jumeaux, a novel Drosophila winged-helix family protein, is required for generating asymmetric sibling neuronal cell fates. Development (2000) 0.94
Alternative splicing in a novel tyrosine phosphatase gene (DPTP4E) of Drosophila melanogaster generates two large receptor-like proteins which differ in their carboxyl termini. J Biol Chem (1993) 0.93
Cloning of DNA fragments from the left end of the adenovirus type 12 genome: transformation by cloned early region 1. J Gen Virol (1982) 0.93
The class I major histocompatibility antigen gene activated in a line of SV40-transformed mouse cells is H-2Dd, not Qa/Tla. Nature (1985) 0.93